Isomannide-based peptidomimetics as inhibitors for human tissue kallikreins 5 and 7

ACS Medicinal Chemistry Letters

Volumn 5, Issue 2, 2014, Pages 128-132

  Oliveira, Jocelia P C ^a   Freitas, Renato F ^b   Melo, Leandro Silva De ^a   Barros, Thalita G ^c   Santos, Jorge A N ^d   Juliano, Maria A ^e   Pinheiro, Sérgio ^c   Blaber, Michael ^f   Juliano, Luiz ^e   Muri, Estela M F ^c   Puzer, Luciano ^a  

^a UNIVERSIDADE FEDERAL DO ABC   (Brazil)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

^d Instituto Federal de Educação Cieîncia e Tecnologia Do sul de Minas Gerais   (Brazil)

^e FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^f FLORIDA STATE UNIVERSITY   (United States)

Author keywords

inhibitor; kallikrein; molecular dynamics; peptidomimetics; Serine protease

Indexed keywords

AMIDE; AMINO ACID; ENZYME INHIBITOR; ESTER DERIVATIVE; KALLIKREIN 5; PEPTIDOMIMETIC AGENT; STRATUM CORNEUM CHYMOTRYPTIC ENZYME;

ARTICLE; BINDING SITE; COMPETITIVE INHIBITION; CONFORMATION; DERMATITIS; ENZYME KINETICS; HUMAN; HUMAN TISSUE; HYDROGEN BOND; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; PRIORITY JOURNAL; SKIN CANCER; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

EID: 84894063427     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml4003698     Document Type: Article

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