Roscovitine suppresses CD4+ T cells and T cell-mediated experimental uveitis

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Zhang, Zili ^a,b   Liu, Qi ^a   Leskov, Konstantin S ^a   Wu, Xiumei ^b   Duan, Jie ^b   Zhang, Gary L ^b   Hall, Mark ^b   Rosenbaum, James T ^c,d  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d DEVERS EYE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CD134 ANTIGEN; CD28 ANTIGEN; CD3 ANTIGEN; CD44 PROTEIN, MOUSE; CDK2 PROTEIN, MOUSE; CYCLIN DEPENDENT KINASE 2; HERMES ANTIGEN; IMMUNOLOGIC FACTOR; OVALBUMIN; PROTEIN KINASE INHIBITOR; PURINE DERIVATIVE; ROSCOVITINE; TNFRSF4 PROTEIN, MOUSE;

ANIMAL; ANTAGONISTS AND INHIBITORS; AUTOIMMUNE DISEASES; BAGG ALBINO MOUSE; C57BL MOUSE; CD4+ T LYMPHOCYTE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CHEMICALLY INDUCED; DRUG EFFECTS; GENE EXPRESSION; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MOUSE; PATHOLOGY; UVEITIS;

ANIMALS; ANTIBODIES; ANTIGENS, CD28; ANTIGENS, CD3; ANTIGENS, CD44; AUTOIMMUNE DISEASES; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE 2; G1 PHASE; GENE EXPRESSION; IMMUNOLOGIC FACTORS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; OVALBUMIN; PROTEIN KINASE INHIBITORS; PURINES; RECEPTORS, OX40; S PHASE; UVEITIS;

EID: 84894044537     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0081154     Document Type: Article

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