The antitumor agent PBT-1 directly targets HSP90 and hnRNP A2/B1 and inhibits lung adenocarcinoma growth and metastasis

Journal of Medicinal Chemistry

Volumn 57, Issue 3, 2014, Pages 677-685

  Chen, Chi Yuan ^a   Yang, Shuenn Chen ^b   Lee, Kuo Hsiung ^c,d   Yang, Xiaoming ^d   Wei, Lin Yi ^d   Chow, Lu Ping ^e,f   Wang, Tzu Chien V ^g   Hong, Tse Ming ^h   Lin, Jau Chen ⁱ   Kuan, Crysline ^j   Yang, Pan Chyr ^b,e  

^a CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^b INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d University of North Carolina at Chapel Hill   (United States)

^e NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^f NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^g CHANG GUNG UNIVERSITY   (Taiwan)

^h NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

ⁱ FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^j UNIVERSITY OF WASHINGTON   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

8,11,14-EICOSATRIENOIC ACID; ADENOCARCINOMA; ANIMALS; ANTINEOPLASTIC AGENTS; CADHERINS; CELL LINE, TUMOR; CELL MOVEMENT; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEIN GROUP A-B; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LUNG NEOPLASMS; MALE; MICE; MICE, NUDE; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASM TRANSPLANTATION; PROTO-ONCOGENE PROTEINS C-AKT; PSEUDOPODIA;

EID: 84894030819     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm401686b     Document Type: Article

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