In vitro cytotoxic activity of phenanthroindolizidine alkaloids from Cynanchum vincetoxicum and Tylophora tanakae against drug-sensitive and multidrug-resistant cancer cells

Journal of Natural Products

Volumn 65, Issue 9, 2002, Pages 1299-1302

  Steerk, Dan ^a   Lykkeberg, Anne K ^a   Christensen, Jette ^a   Budnik, Bogdan A ^b   Abe, Fumiko ^c   Jaroszewski, Jerzy W ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^c FUKUOKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

13A ALPHA 6 O NORANTOFINE; 13A ALPHA 6 O NORSECANTOFINE; 13A ALPHA 7 O NORTYLOPHORINE; 13A ALPHA ANTOFINE; 13A ALPHA SECOANTOFINE; 13A ALPHA TYLOPHORINE; 13A BETA ISOTYLOCREBRINE; CYTOTOXIC AGENT; INDOLE ALKALOID; PHENANTHROINDOLIZIDINE ALKALOID; RHODAMINE 123; UNCLASSIFIED DRUG; VINBLASTINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER; CANCER CELL CULTURE; CANCER RESISTANCE; CARBON NUCLEAR MAGNETIC RESONANCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYNANCHUM VINCETOXICUM; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG SENSITIVITY; DRUG STRUCTURE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MEDICINAL PLANT; MULTIDRUG RESISTANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; OPTICAL ROTATION; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; TYLOPHORA TANAKAE;

ALKALOIDS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CYNANCHUM; DENMARK; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; INDOLES; INHIBITORY CONCENTRATION 50; ISOQUINOLINES; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHENANTHRENES; PLANT LEAVES; PLANTS, MEDICINAL; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED; UTERINE CERVICAL NEOPLASMS; VINBLASTINE;

CYNANCHUM; CYNANCHUM VINCETOXICUM; TYLOPHORA; TYLOPHORA TANAKAE; VINCETOXICUM;

EID: 0036743304     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np0106384     Document Type: Article

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