Rapid identification of Keap1-Nrf2 small-molecule inhibitors through structure-based virtual screening and hit-based substructure search

Journal of Medicinal Chemistry

Volumn 57, Issue 3, 2014, Pages 1121-1126

  Zhuang, Chunlin ^a,b   Narayanapillai, Sreekanth ^a   Zhang, Wannian ^b   Sham, Yuk Yin ^c   Xing, Chengguo ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE TRANSPORT, CELL NUCLEUS; AMIDES; ANIMALS; BENZENE DERIVATIVES; CELL NUCLEUS; COMPUTER SIMULATION; DATABASES, CHEMICAL; DRUG DESIGN; FURANS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MOLECULAR DOCKING SIMULATION; NAPHTHALENES; PC12 CELLS; PROTEIN BINDING; PYRROLES; RATS; RNA, MESSENGER; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES; THIAZOLES;

EID: 84894024670     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm4017174     Document Type: Article

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