-
1
-
-
34548036227
-
Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
-
Ballatore C, Lee VM, Trojanowski JQ (2007) Tau-mediated neurodegeneration in Alzheimer's disease and related disorders. Nat Rev Neurosci 8, 663-672.
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 663-672
-
-
Ballatore, C.1
Lee, V.M.2
Trojanowski, J.Q.3
-
2
-
-
0026001490
-
The effect of tau antisense oligonucleotides on neurite formation of cultured cerebellar macroneurons
-
Caceres A, Potrebic S, Kosik KS (1991) The effect of tau antisense oligonucleotides on neurite formation of cultured cerebellar macroneurons. J Neurosci 11, 1515-1523.
-
(1991)
J Neurosci
, vol.11
, pp. 1515-1523
-
-
Caceres, A.1
Potrebic, S.2
Kosik, K.S.3
-
3
-
-
0028316882
-
Sense and antisense transfection analysis of tau function: Tau influences net microtubule assembly, neurite outgrowth and neuritic stability
-
Esmaeli-Azad B, McCarty JH, Feinstein SC (1994) Sense and antisense transfection analysis of tau function: Tau influences net microtubule assembly, neurite outgrowth and neuritic stability. J Cell Sci 107(Pt 4), 869-879.
-
(1994)
J Cell Sci
, vol.107
, Issue.PART 4
, pp. 869-879
-
-
Esmaeli-Azad, B.1
McCarty, J.H.2
Feinstein, S.C.3
-
4
-
-
0034605045
-
Defects in axonal elongation and neuronal migration in mice with disrupted tau and map1b genes
-
Takei Y, Teng J, Harada A, Hirokawa N (2000) Defects in axonal elongation and neuronal migration in mice with disrupted tau and map1b genes. J Cell Biol 150, 989-1000.
-
(2000)
J Cell Biol
, vol.150
, pp. 989-1000
-
-
Takei, Y.1
Teng, J.2
Harada, A.3
Hirokawa, N.4
-
5
-
-
84863337843
-
Alzheimer mechanisms and therapeutic strategies
-
Huang Y, Mucke L (2012) Alzheimer mechanisms and therapeutic strategies. Cell 148, 1204-1222.
-
(2012)
Cell
, vol.148
, pp. 1204-1222
-
-
Huang, Y.1
Mucke, L.2
-
7
-
-
0032543684
-
Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17
-
Hutton M, Lendon CL, Rizzu P, Baker M, Froelich S, Houlden H, Pickering-Brown S, Chakraverty S, Isaacs A, Grover A, Hackett J, Adamson J, Lincoln S, Dickson D, Davies P, Petersen RC, Stevens M, de Graaff E, Wauters E, van Baren J, Hillebrand M, Joosse M, Kwon JM, Nowotny P, Che LK, Norton J, Morris JC, Reed LA, Trojanowski J, Basun H, Lannfelt L, Neystat M, Fahn S, Dark F, Tannenberg T, Dodd PR, Hayward N, Kwok JB, Schofield PR, Andreadis A, Snowden J, Craufurd D, Neary D, Owen F, Oostra BA, Hardy J, Goate A, van Swieten J, Mann D, Lynch T, Heutink P (1998) Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17. Nature 393, 702-705.
-
(1998)
Nature
, vol.393
, pp. 702-705
-
-
Hutton, M.1
Lendon, C.L.2
Rizzu, P.3
Baker, M.4
Froelich, S.5
Houlden, H.6
Pickering-Brown, S.7
Chakraverty, S.8
Isaacs, A.9
Grover, A.10
Hackett, J.11
Adamson, J.12
Lincoln, S.13
Dickson, D.14
Davies, P.15
Petersen, R.C.16
Stevens, M.17
De Graaff, E.18
Wauters, E.19
Van Baren, J.20
Hillebrand, M.21
Joosse, M.22
Kwon, J.M.23
Nowotny, P.24
Che, L.K.25
Norton, J.26
Morris, J.C.27
Reed, L.A.28
Trojanowski, J.29
Basun, H.30
Lannfelt, L.31
Neystat, M.32
Fahn, S.33
Dark, F.34
Tannenberg, T.35
Dodd, P.R.36
Hayward, N.37
Kwok, J.B.38
Schofield, P.R.39
Andreadis, A.40
Snowden, J.41
Craufurd, D.42
Neary, D.43
Owen, F.44
Oostra, B.A.45
Hardy, J.46
Goate, A.47
Van Swieten, J.48
Mann, D.49
Lynch, T.50
Heutink, P.51
more..
-
8
-
-
0032484089
-
Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17
-
Hong M, Zhukareva V, Vogelsberg-Ragaglia V, Wszolek Z, Reed L, Miller BI, Geschwind DH, Bird TD, McKeel D, Goate A, Morris JC,Wilhelmsen KC, Schellenberg GD, Trojanowski JQ, Lee VM (1998) Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17. Science 282, 1914-1917.
-
(1998)
Science
, vol.282
, pp. 1914-1917
-
-
Hong, M.1
Zhukareva, V.2
Vogelsberg-Ragaglia, V.3
Wszolek, Z.4
Reed, L.5
Miller, B.I.6
Geschwind, D.H.7
Bird, T.D.8
McKeel, D.9
Goate, A.10
Morris, J.C.11
Wilhelmsen, K.C.12
Schellenberg, G.D.13
Trojanowski, J.Q.14
Lee, V.M.15
-
9
-
-
0032573083
-
Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17
-
Clark LN, Poorkaj P, Wszolek Z, Geschwind DH, Nasreddine ZS, Miller B, Li D, Payami H, Awert F, Markopoulou K, Andreadis A, D'Souza I, Lee VM, Reed L, Trojanowski JQ, Zhukareva V, Bird T, Schellenberg G, Wilhelmsen KC (1998) Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17. Proc Natl Acad Sci U S A 95, 13103-13107.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 13103-13107
-
-
Clark, L.N.1
Poorkaj, P.2
Wszolek, Z.3
Geschwind, D.H.4
Nasreddine, Z.S.5
Miller, B.6
Li, D.7
Payami, H.8
Awert, F.9
Markopoulou, K.10
Andreadis, A.11
D'Souza, I.12
Lee, V.M.13
Reed, L.14
Trojanowski, J.Q.15
Zhukareva, V.16
Bird, T.17
Schellenberg, G.18
Wilhelmsen, K.C.19
-
10
-
-
0032560487
-
Mutation in the tau gene in familial multiple system tauopathy with presenile dementia
-
Spillantini MG, Murrell JR, Goedert M, FarlowMR, Klug A, Ghetti B (1998) Mutation in the tau gene in familial multiple system tauopathy with presenile dementia. Proc Natl Acad Sci U S A 95, 7737-7741.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 7737-7741
-
-
Spillantini, M.G.1
Murrell, J.R.2
Goedert, M.3
Farlow, M.R.4
Klug, A.5
Ghetti, B.6
-
11
-
-
0033663879
-
A novel tau mutation (N296N) in familial dementia with swollen achromatic neurons and corticobasal inclusion bodies
-
Spillantini M, Yoshida H, Rizzini C, Lantos PL, Khan N, Rossor MN, Goedert M, Brown J (2000) A novel tau mutation (N296N) in familial dementia with swollen achromatic neurons and corticobasal inclusion bodies. Ann Neurol 48, 939-943.
-
(2000)
Ann Neurol
, vol.48
, pp. 939-943
-
-
Spillantini, M.1
Yoshida, H.2
Rizzini, C.3
Lantos, P.L.4
Khan, N.5
Rossor, M.N.6
Goedert, M.7
Brown, J.8
-
12
-
-
0024507707
-
Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable Nterminal domains
-
Himmler A, Drechsel D, Kirschner MW, Martin DW, Jr. (1989) Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable Nterminal domains. Mol Cell Biol 9, 1381-1388.
-
(1989)
Mol Cell Biol
, vol.9
, pp. 1381-1388
-
-
Himmler, A.1
Drechsel, D.2
Kirschner, M.W.3
Martin Jr., D.W.4
-
13
-
-
0024641959
-
Developmentally regulated expression of specific tau sequences
-
Kosik KS, Orecchio LD, Bakalis S, Neve RL (1989) Developmentally regulated expression of specific tau sequences. Neuron 2, 1389-1397.
-
(1989)
Neuron
, vol.2
, pp. 1389-1397
-
-
Kosik, K.S.1
Orecchio, L.D.2
Bakalis, S.3
Neve, R.L.4
-
14
-
-
0024498630
-
Structure of the bovine tau gene: Alternatively spliced transcripts generate a protein family
-
Himmler A (1989) Structure of the bovine tau gene: Alternatively spliced transcripts generate a protein family. Mol Cell Biol 9, 1389-1396.
-
(1989)
Mol Cell Biol
, vol.9
, pp. 1389-1396
-
-
Himmler, A.1
-
15
-
-
70350455072
-
Axonal transport defects in neurodegenerative diseases
-
Morfini GA, Burns M, Binder LI, Kanaan NM, LaPointe N, Bosco DA, Brown RH Jr, Brown H, Tiwari A, Hayward L, Edgar J, Nave KA, Garberrn J, Atagi Y, Song Y, Pigino G, Brady ST (2009) Axonal transport defects in neurodegenerative diseases. J Neurosci 29, 12776-12786.
-
(2009)
J Neurosci
, vol.29
, pp. 12776-12786
-
-
Morfini, G.A.1
Burns, M.2
Binder, L.I.3
Kanaan, N.M.4
LaPointe, N.5
Bosco, D.A.6
Brown Jr., R.H.7
Brown, H.8
Tiwari, A.9
Hayward, L.10
Edgar, J.11
Nave, K.A.12
Garberrn, J.13
Atagi, Y.14
Song, Y.15
Pigino, G.16
Brady, S.T.17
-
16
-
-
84856056846
-
Mitochondrial transport in neurons: Impact on synaptic homeostasis and neurodegeneration
-
Sheng Z-H, Cai Q (2012) Mitochondrial transport in neurons: Impact on synaptic homeostasis and neurodegeneration. Nat Rev Neurosci 13, 77-93.
-
(2012)
Nat Rev Neurosci
, vol.13
, pp. 77-93
-
-
Sheng, Z.-H.1
Cai, Q.2
-
17
-
-
20044385920
-
Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease
-
Stokin GB, Lillo C, Falzone TL, Brusch RG, Rockenstein E, Mount SL, Raman R, Davies P, Masliah E, Williams DS, Goldstein LS (2005) Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease. Science 307, 1282-1288.
-
(2005)
Science
, vol.307
, pp. 1282-1288
-
-
Stokin, G.B.1
Lillo, C.2
Falzone, T.L.3
Brusch, R.G.4
Rockenstein, E.5
Mount, S.L.6
Raman, R.7
Davies, P.8
Masliah, E.9
Williams, D.S.10
Goldstein, L.S.11
-
18
-
-
0037128935
-
Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
-
Stamer K, Vogel R, Thies E, Mandelkow E, Mandelkow EM (2002) Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress. J Cell Biol 156, 1051-1063.
-
(2002)
J Cell Biol
, vol.156
, pp. 1051-1063
-
-
Stamer, K.1
Vogel, R.2
Thies, E.3
Mandelkow, E.4
Mandelkow, E.M.5
-
19
-
-
0032476645
-
Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: Implications for Alzheimer's disease
-
Ebneth A, Godemann R, Stamer K, Illenberger S, Trinczek B, Mandelkow E (1998) Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum: Implications for Alzheimer's disease. J Cell Biol 143, 777-794.
-
(1998)
J Cell Biol
, vol.143
, pp. 777-794
-
-
Ebneth, A.1
Godemann, R.2
Stamer, K.3
Illenberger, S.4
Trinczek, B.5
Mandelkow, E.6
-
20
-
-
0032799381
-
Tau regulates the attachment/detachment but not the speed of motors in microtubule-dependent transport of single vesicles and organelles
-
Trinczek B, Ebneth A, Mandelkow EM, Mandelkow E (1999) Tau regulates the attachment/detachment but not the speed of motors in microtubule-dependent transport of single vesicles and organelles. J Cell Sci 112(Pt 14), 2355-2367.
-
(1999)
J Cell Sci
, vol.112
, Issue.PART 14
, pp. 2355-2367
-
-
Trinczek, B.1
Ebneth, A.2
Mandelkow, E.M.3
Mandelkow, E.4
-
21
-
-
0345276565
-
Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses
-
Mandelkow EM, Stamer K, Vogel R, Thies E, Mandelkow E (2003) Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses. Neurobiol Aging 24, 1079-1085.
-
(2003)
Neurobiol Aging
, vol.24
, pp. 1079-1085
-
-
Mandelkow, E.M.1
Stamer, K.2
Vogel, R.3
Thies, E.4
Mandelkow, E.5
-
22
-
-
0032786370
-
Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein
-
Spittaels K, Van den Haute C, Van Dorpe J, Bruynseels K, Vandezande K, Laenen I, Geerts H, Mercken M, Sciot R, Van Lommel A, Loos R, Van Leuven F (1999) Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein. Am J Pathol 155, 2153-2165.
-
(1999)
Am J Pathol
, vol.155
, pp. 2153-2165
-
-
Spittaels, K.1
Van Den Haute, C.2
Van Dorpe, J.3
Bruynseels, K.4
Vandezande, K.5
Laenen, I.6
Geerts, H.7
Mercken, M.8
Sciot, R.9
Van Lommel, A.10
Loos, R.11
Van Leuven, F.12
-
23
-
-
39549117998
-
Axonal transport rates in vivo are unaffected by tau deletion or overexpression in mice
-
Yuan A, Kumar A, Peterhoff C, Duff K, Nixon RA (2008) Axonal transport rates in vivo are unaffected by tau deletion or overexpression in mice. J Neurosci 28, 1682-1687.
-
(2008)
J Neurosci
, vol.28
, pp. 1682-1687
-
-
Yuan, A.1
Kumar, A.2
Peterhoff, C.3
Duff, K.4
Nixon, R.A.5
-
24
-
-
34250317264
-
Tau binding to microtubules does not directly affect microtubule-based vesicle motility
-
Morfini G, Pigino G, Mizuno N, Kikkawa M, Brady ST (2007) Tau binding to microtubules does not directly affect microtubule-based vesicle motility. J Neurosci Res 85, 2620-2630.
-
(2007)
J Neurosci Res
, vol.85
, pp. 2620-2630
-
-
Morfini, G.1
Pigino, G.2
Mizuno, N.3
Kikkawa, M.4
Brady, S.T.5
-
25
-
-
0037119947
-
Single-molecule investigation of the interference between kinesin, tau and MAP2c
-
Seitz A, Kojima H, Oiwa K, Mandelkow EM, Song YH, Mandelkow E (2002) Single-molecule investigation of the interference between kinesin, tau and MAP2c. EMBO J 21, 4896-4905.
-
(2002)
EMBO J
, vol.21
, pp. 4896-4905
-
-
Seitz, A.1
Kojima, H.2
Oiwa, K.3
Mandelkow, E.M.4
Song, Y.H.5
Mandelkow, E.6
-
26
-
-
33846118789
-
Multiple-motor based transport and its regulation by Tau
-
Vershinin M, Carter BC, Razafsky DS, King SJ, Gross SP (2007) Multiple-motor based transport and its regulation by Tau. Proc Natl Acad Sci U S A 104, 87-92.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 87-92
-
-
Vershinin, M.1
Carter, B.C.2
Razafsky, D.S.3
King, S.J.4
Gross, S.P.5
-
27
-
-
39749165656
-
Differential regulation of dynein and kinesin motor proteins by tau
-
Dixit R, Ross JL, Goldman YE, Holzbaur EL (2008) Differential regulation of dynein and kinesin motor proteins by tau. Science 319, 1086-1089.
-
(2008)
Science
, vol.319
, pp. 1086-1089
-
-
Dixit, R.1
Ross, J.L.2
Goldman, Y.E.3
Holzbaur, E.L.4
-
28
-
-
0023905288
-
The primary structure and heterogeneity of tau protein from mouse brain
-
Lee G, Cowan N, Kirschner M (1988) The primary structure and heterogeneity of tau protein from mouse brain. Science 239, 285-288.
-
(1988)
Science
, vol.239
, pp. 285-288
-
-
Lee, G.1
Cowan, N.2
Kirschner, M.3
-
29
-
-
0028027088
-
Domains of tau protein and interactions with microtubules
-
GustkeN,Trinczek B, Biernat J, MandelkowEM,Mandelkow E (1994) Domains of tau protein and interactions with microtubules. Biochemistry 33, 9511-9522.
-
(1994)
Biochemistry
, vol.33
, pp. 9511-9522
-
-
Gustke, N.1
Trinczek, B.2
Biernat, J.3
Mandelkow, E.M.4
Mandelkow, E.5
-
30
-
-
0028175215
-
Identification of a novel microtubule binding and assembly domain in the developmentally regulated inter-repeat region of tau
-
Goode BL, Feinstein SC (1994) Identification of a novel microtubule binding and assembly domain in the developmentally regulated inter-repeat region of tau. J Cell Biol 124, 769-782.
-
(1994)
J Cell Biol
, vol.124
, pp. 769-782
-
-
Goode, B.L.1
Feinstein, S.C.2
-
31
-
-
0024094998
-
Tau proteins: The molecular structure and mode of binding on microtubules
-
Hirokawa N, Shiomura Y, Okabe S (1988) Tau proteins: The molecular structure and mode of binding on microtubules. J Cell Biol 107, 1449-1459.
-
(1988)
J Cell Biol
, vol.107
, pp. 1449-1459
-
-
Hirokawa, N.1
Shiomura, Y.2
Okabe, S.3
-
32
-
-
0026046950
-
Tau protein binds to microtubules through a flexible array of distributed weak sites
-
Butner KA, KirschnerMW(1991) Tau protein binds to microtubules through a flexible array of distributed weak sites. J Cell Biol 115, 717-730.
-
(1991)
J Cell Biol
, vol.115
, pp. 717-730
-
-
Butner, K.A.1
Kirschner, M.W.2
-
33
-
-
0029098802
-
Kinetic stabilization of microtubule dynamics at steady state by tau and microtubule-binding domains of tau
-
Panda D, Goode BL, Feinstein SC, Wilson L (1995) Kinetic stabilization of microtubule dynamics at steady state by tau and microtubule-binding domains of tau. Biochemistry 34, 11117-11127.
-
(1995)
Biochemistry
, vol.34
, pp. 11117-11127
-
-
Panda, D.1
Goode, B.L.2
Feinstein, S.C.3
Wilson, L.4
-
34
-
-
0026729767
-
Projection domains of MAP2 and tau determine spacings between microtubules in dendrites and axons
-
Chen J, Kanai Y, Cowan NJ, Hirokawa N (1992) Projection domains of MAP2 and tau determine spacings between microtubules in dendrites and axons. Nature 360, 674-677.
-
(1992)
Nature
, vol.360
, pp. 674-677
-
-
Chen, J.1
Kanai, Y.2
Cowan, N.J.3
Hirokawa, N.4
-
35
-
-
68949101914
-
Human microtubule-associated-protein tau regulates the number of protofilaments in microtubules: A synchrotron x-ray scattering study
-
Choi MC, Raviv U, Miller HP, Gaylord MR, Kiris E, Ventimiglia D, Needleman DJ, KimMW,Wilson L, Feinstein SC, Safinya CR (2009) Human microtubule-associated-protein tau regulates the number of protofilaments in microtubules: A synchrotron x-ray scattering study. Biophys J 97, 519-527.
-
(2009)
Biophys J
, vol.97
, pp. 519-527
-
-
Choi, M.C.1
Raviv, U.2
Miller, H.P.3
Gaylord, M.R.4
Kiris, E.5
Ventimiglia, D.6
Needleman, D.J.7
Kim, M.W.8
Wilson, L.9
Feinstein, S.C.10
Safinya, C.R.11
-
36
-
-
0032509226
-
Changes in microtubule protofilament number induced by Taxol binding to an easily accessible site. Internal microtubule dynamics
-
Diaz JF, Valpuesta JM, Chacon P, Diakun G, Andreu JM (1998) Changes in microtubule protofilament number induced by Taxol binding to an easily accessible site. Internal microtubule dynamics. J Biol Chem 273, 33803-33810.
-
(1998)
J Biol Chem
, vol.273
, pp. 33803-33810
-
-
Diaz, J.F.1
Valpuesta, J.M.2
Chacon, P.3
Diakun, G.4
Andreu, J.M.5
-
37
-
-
0042924434
-
Differential regulation of microtubule dynamics by three-and four-repeat tau: Implications for the onset of neurodegenerative disease
-
Panda D, Samuel JC, Massie M, Feinstein SC, Wilson L (2003) Differential regulation of microtubule dynamics by three-and four-repeat tau: Implications for the onset of neurodegenerative disease. Proc Natl Acad Sci U S A 100, 9548-9553.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 9548-9553
-
-
Panda, D.1
Samuel, J.C.2
Massie, M.3
Feinstein, S.C.4
Wilson, L.5
-
38
-
-
0028908695
-
Substoichiometric binding of taxol suppresses microtubule dynamics
-
Derry WB, Wilson L, Jordan MA (1995) Substoichiometric binding of taxol suppresses microtubule dynamics. Biochemistry 34, 2203-2211.
-
(1995)
Biochemistry
, vol.34
, pp. 2203-2211
-
-
Derry, W.B.1
Wilson, L.2
Jordan, M.A.3
-
39
-
-
14744280774
-
Long-range cooperative binding of kinesin to a microtubule in the presence of ATP
-
Muto E, Sakai H, Kaseda K (2005) Long-range cooperative binding of kinesin to a microtubule in the presence of ATP. J Cell Biol 168, 691-696.
-
(2005)
J Cell Biol
, vol.168
, pp. 691-696
-
-
Muto, E.1
Sakai, H.2
Kaseda, K.3
-
40
-
-
33745918018
-
Insights into the mechanism of microtubule stabilization by Taxol
-
Xiao H, Verdier-Pinard P, Fernandez-Fuentes N, Burd B, Angeletti R, Fiser A, Horwitz SB, Orr GA (2006) Insights into the mechanism of microtubule stabilization by Taxol. Proc Natl Acad Sci U S A 103, 10166-10173.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 10166-10173
-
-
Xiao, H.1
Verdier-Pinard, P.2
Fernandez-Fuentes, N.3
Burd, B.4
Angeletti, R.5
Fiser, A.6
Horwitz, S.B.7
Orr, G.A.8
-
41
-
-
0345118121
-
Complex formation with kinesin motor domains affects the structure of microtubules
-
Krebs A, Goldie KN, Hoenger A (2004) Complex formation with kinesin motor domains affects the structure of microtubules. J Mol Biol 335, 139-153.
-
(2004)
J Mol Biol
, vol.335
, pp. 139-153
-
-
Krebs, A.1
Goldie, K.N.2
Hoenger, A.3
-
42
-
-
84875903817
-
Mechanical properties of doubly stabilized microtubule filaments
-
Hawkins TL, Sept D, Mogessie B, Straube A, Ross JL (2013) Mechanical properties of doubly stabilized microtubule filaments. Biophys J 104, 1517-1528.
-
(2013)
Biophys J
, vol.104
, pp. 1517-1528
-
-
Hawkins, T.L.1
Sept, D.2
Mogessie, B.3
Straube, A.4
Ross, J.L.5
-
43
-
-
83355163345
-
The Nucleotidebinding state of microtubules modulates kinesin processivity and the ability of tau to inhibit kinesin-mediated transport
-
McVicker DP, Chrin LR, Berger CL (2012) The Nucleotidebinding state of microtubules modulates kinesin processivity and the ability of tau to inhibit kinesin-mediated transport. J Biol Chem 286, 42873-42880.
-
(2012)
J Biol Chem
, vol.286
, pp. 42873-42880
-
-
McVicker, D.P.1
Chrin, L.R.2
Berger, C.L.3
-
44
-
-
78650217997
-
Tau isoform-specific modulation of kinesin-driven microtubule gliding rates and trajectories as determined with tau-stabilized microtubules
-
Peck A, Sargin ME, LaPointe NE, Rose K, Manjunath BS, Feinstein SC, Wilson L (2011) Tau isoform-specific modulation of kinesin-driven microtubule gliding rates and trajectories as determined with tau-stabilized microtubules. Cytoskeleton 68, 44-55.
-
(2011)
Cytoskeleton
, vol.68
, pp. 44-55
-
-
Peck, A.1
Sargin, M.E.2
LaPointe, N.E.3
Rose, K.4
Manjunath, B.S.5
Feinstein, S.C.6
Wilson, L.7
-
45
-
-
77955288077
-
Preparation of microtubule protein and purified tubulin from bovine brain by cycles of assembly and disassembly and phosphocellulose chromatography
-
Wilson L, Correia, JJ, eds. Elsevier Inc., Amsterdam
-
Miller HP, Wilson L (2010) Preparation of microtubule protein and purified tubulin from bovine brain by cycles of assembly and disassembly and phosphocellulose chromatography. In Methods in Cell Biology,Wilson L, Correia, JJ, eds. Elsevier Inc., Amsterdam, pp. 3-15.
-
(2010)
Methods in Cell Biology
, pp. 3-15
-
-
Miller, H.P.1
Wilson, L.2
-
46
-
-
0025762199
-
Preparation of modified tubulins
-
Hyman A, Drechsel D, Kellogg D, Salser S, Sawin K, Steffen P, Wordeman L, Mitchison T (1991) Preparation of modified tubulins. Methods Enzymol 196, 478-485.
-
(1991)
Methods Enzymol
, vol.196
, pp. 478-485
-
-
Hyman, A.1
Drechsel, D.2
Kellogg, D.3
Salser, S.4
Sawin, K.5
Steffen, P.6
Wordeman, L.7
Mitchison, T.8
-
47
-
-
17144409371
-
Three-and four-repeat tau regulate the dynamic instability of two distinct microtubule subpopulations in qualitatively different manners. Implications for neurodegeneration
-
Levy SF, Leboeuf AC, Massie MR, Jordan MA, Wilson L, Feinstein SC (2005) Three-and four-repeat tau regulate the dynamic instability of two distinct microtubule subpopulations in qualitatively different manners. Implications for neurodegeneration. J Biol Chem 280, 13520-13528.
-
(2005)
J Biol Chem
, vol.280
, pp. 13520-13528
-
-
Levy, S.F.1
Leboeuf, A.C.2
Massie, M.R.3
Jordan, M.A.4
Wilson, L.5
Feinstein, S.C.6
-
48
-
-
0033576727
-
A structural change in the kinesin motor protein that drives motility
-
Rice S, Lin AW, Safer D, Hart CL, Naber N, Carragher BO, Cain SM, PechatnikovaE,Wilson-KubalekEM,Whittaker M, Pate E, Cooke R, Taylor EW, Milligan RA, Vale RD (1999) A structural change in the kinesin motor protein that drives motility. Nature 402, 778-784.
-
(1999)
Nature
, vol.402
, pp. 778-784
-
-
Rice, S.1
Lin, A.W.2
Safer, D.3
Hart, C.L.4
Naber, N.5
Carragher, B.O.6
Cain, S.M.7
Pechatnikova, E.8
Wilson-Kubalek, E.M.9
Whittaker, M.10
Pate, E.11
Cooke, R.12
Taylor, E.W.13
Milligan, R.A.14
Vale, R.D.15
-
49
-
-
0030874883
-
The directional preference of kinesin motors is specified by an element outside of the motor catalytic domain
-
Case RB, Pierce DW, Hom-Booher N, Hart CL, Vale RD (1997) The directional preference of kinesin motors is specified by an element outside of the motor catalytic domain. Cell 90, 959-966.
-
(1997)
Cell
, vol.90
, pp. 959-966
-
-
Case, R.B.1
Pierce, D.W.2
Hom-Booher, N.3
Hart, C.L.4
Vale, R.D.5
-
50
-
-
0019849247
-
Taxol induces microtubule assembly at low temperature
-
Thompson WC, Wilson L, Purich DL (1981) Taxol induces microtubule assembly at low temperature. Cell Motil 1, 445-454.
-
(1981)
Cell Motil
, vol.1
, pp. 445-454
-
-
Thompson, W.C.1
Wilson, L.2
Purich, D.L.3
-
51
-
-
51549097934
-
Intramolecular strain coordinates kinesin stepping behavior along microtubules
-
Yildiz A, Tomishige M, Gennerich A, Vale RD (2008) Intramolecular strain coordinates kinesin stepping behavior along microtubules. Cell 134, 1030-1041.
-
(2008)
Cell
, vol.134
, pp. 1030-1041
-
-
Yildiz, A.1
Tomishige, M.2
Gennerich, A.3
Vale, R.D.4
-
52
-
-
34447250290
-
Bending dynamics of fluctuating biopolymers probed by automated high-resolution filament tracking
-
Brangwynne CP, Koenderink GH, Barry E, Dogic Z, MacKintosh FC,Weitz DA (2007) Bending dynamics of fluctuating biopolymers probed by automated high-resolution filament tracking. Biophys J 93, 346-359.
-
(2007)
Biophys J
, vol.93
, pp. 346-359
-
-
Brangwynne, C.P.1
Koenderink, G.H.2
Barry, E.3
Dogic, Z.4
MacKintosh, F.C.5
Weitz, D.A.6
-
53
-
-
84858054734
-
Spectral analysis methods for the robust measurement of the flexural rigidity of biopolymers
-
Valdman D, Atzberger Paul J, Yu D, Kuei S, Valentine Megan T (2012) Spectral analysis methods for the robust measurement of the flexural rigidity of biopolymers. Biophy J 102, 1144-1153.
-
(2012)
Biophy J
, vol.102
, pp. 1144-1153
-
-
Valdman, D.1
Atzberger Paul, J.2
Yu, D.3
Kuei, S.4
Valentine Megan, T.5
-
54
-
-
0022365608
-
The distribution of tau in the mammalian central nervous system
-
Binder LI, Frankfurter A, Rebhun LI (1985) The distribution of tau in the mammalian central nervous system. J Cell Biol 101, 1371-1378.
-
(1985)
J Cell Biol
, vol.101
, pp. 1371-1378
-
-
Binder, L.I.1
Frankfurter, A.2
Rebhun, L.I.3
-
55
-
-
0022395021
-
Nerve growth factor-induced neurite outgrowth in PC12 cells involves the coordinate induction of microtubule assembly and assembly-promoting factors
-
Drubin DG, Feinstein SC, Shooter EM, KirschnerMW(1985) Nerve growth factor-induced neurite outgrowth in PC12 cells involves the coordinate induction of microtubule assembly and assembly-promoting factors. J Cell Biol 101, 1799-1807.
-
(1985)
J Cell Biol
, vol.101
, pp. 1799-1807
-
-
Drubin, D.G.1
Feinstein, S.C.2
Shooter, E.M.3
Kirschner, M.W.4
-
56
-
-
0027273502
-
Porters versus rowers: A unified stochastic model of motor proteins
-
Leibler S, Huse DA (1993) Porters versus rowers: A unified stochastic model of motor proteins. J Cell Biol 121, 1357-1368.
-
(1993)
J Cell Biol
, vol.121
, pp. 1357-1368
-
-
Leibler, S.1
Huse, D.A.2
-
57
-
-
60349132064
-
The role of neuroimmunomodulation in Alzheimer's disease
-
Maccioni RB, Rojo LE, Fernandez JA, Kuljis RO (2009) The role of neuroimmunomodulation in Alzheimer's disease. Ann N Y Acad Sci 1153, 240-246.
-
(2009)
Ann N Y Acad Sci
, vol.1153
, pp. 240-246
-
-
Maccioni, R.B.1
Rojo, L.E.2
Fernandez, J.A.3
Kuljis, R.O.4
-
58
-
-
0028820411
-
Domains of tau protein, differential phosphorylation, and dynamic instability of microtubules
-
Trinczek B, Biernat J, Baumann K, Mandelkow EM, Mandelkow E (1995) Domains of tau protein, differential phosphorylation, and dynamic instability of microtubules. Mol Biol Cell 6, 1887-1902.
-
(1995)
Mol Biol Cell
, vol.6
, pp. 1887-1902
-
-
Trinczek, B.1
Biernat, J.2
Baumann, K.3
Mandelkow, E.M.4
Mandelkow, E.5
-
59
-
-
0024675418
-
The microtubule binding domain of tau protein
-
Lee G, Neve RL, Kosik KS (1989) The microtubule binding domain of tau protein. Neuron 2, 1615-1624.
-
(1989)
Neuron
, vol.2
, pp. 1615-1624
-
-
Lee, G.1
Neve, R.L.2
Kosik, K.S.3
-
60
-
-
0037088687
-
Functional characterization of FTDP-17 tau gene mutations through their effects on Xenopus oocyte maturation
-
Delobel P, Flament S, Hamdane M, Jakes R, Rousseau A, Delacourte A,Vilain JP, Goedert M, BueeL(2002) Functional characterization of FTDP-17 tau gene mutations through their effects on Xenopus oocyte maturation. J BiolChem277, 9199-9205.
-
(2002)
J BiolChem
, vol.277
, pp. 9199-9205
-
-
Delobel, P.1
Flament, S.2
Hamdane, M.3
Jakes, R.4
Rousseau, A.5
Delacourte, A.6
Vilain, J.P.7
Goedert, M.8
Buee, L.9
-
61
-
-
61349120799
-
FTDP-17 mutations in tau alter the regulation of microtubule dynamics-an "Alternative Core" model for normal and pathological tau action
-
LeBoeuf AC, Levy SF, Gaylord M, Bhattacharya A, Singh AK, Jordan MA, Wilson L, Feinstein SC (2008) FTDP-17 mutations in tau alter the regulation of microtubule dynamics-an "Alternative Core" model for normal and pathological tau action. J Biol Chem 283, 36406-36415.
-
(2008)
J Biol Chem
, vol.283
, pp. 36406-36415
-
-
LeBoeuf, A.C.1
Levy, S.F.2
Gaylord, M.3
Bhattacharya, A.4
Singh, A.K.5
Jordan, M.A.6
Wilson, L.7
Feinstein, S.C.8
-
62
-
-
33744952341
-
FTDP-17 mutations compromise the ability of tau to regulate microtubule dynamics in cells
-
Bunker JM, Kamath K, Wilson L, Jordan MA, Feinstein SC (2006) FTDP-17 mutations compromise the ability of tau to regulate microtubule dynamics in cells. J Biol Chem 281, 11856-11863.
-
(2006)
J Biol Chem
, vol.281
, pp. 11856-11863
-
-
Bunker, J.M.1
Kamath, K.2
Wilson, L.3
Jordan, M.A.4
Feinstein, S.C.5
-
63
-
-
0034624014
-
Structural and functional differences between 3-repeat and 4-repeat tau isoforms. Implications for normal tau function and the onset of neurodegenetative disease
-
Goode BL, Chau M, Denis PE, Feinstein SC (2000) Structural and functional differences between 3-repeat and 4-repeat tau isoforms. Implications for normal tau function and the onset of neurodegenetative disease. J Biol Chem 275, 38182-38189.
-
(2000)
J Biol Chem
, vol.275
, pp. 38182-38189
-
-
Goode, B.L.1
Chau, M.2
Denis, P.E.3
Feinstein, S.C.4
-
64
-
-
0035996975
-
Relating molecular flexibility to function: A case study of tubulin
-
Keskin O, Durell SR, Bahar I, Jernigan RL, CovellDG(2002) Relating molecular flexibility to function: A case study of tubulin. Biophys J 83, 663-680.
-
(2002)
Biophys J
, vol.83
, pp. 663-680
-
-
Keskin, O.1
Durell, S.R.2
Bahar, I.3
Jernigan, R.L.4
Covell, D.G.5
-
65
-
-
0027058857
-
Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau
-
Drechsel DN, Hyman AA, Cobb MH, Kirschner MW (1992) Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau. Mol Biol Cell 3, 1141-1154.
-
(1992)
Mol Biol Cell
, vol.3
, pp. 1141-1154
-
-
Drechsel, D.N.1
Hyman, A.A.2
Cobb, M.H.3
Kirschner, M.W.4
-
66
-
-
0037413708
-
Repeat motifs of tau bind to the insides of microtubules in the absence of taxol
-
Kar S, Fan J, Smith MJ, Goedert M, Amos LA (2003) Repeat motifs of tau bind to the insides of microtubules in the absence of taxol. EMBO J 22, 70-77.
-
(2003)
EMBO J
, vol.22
, pp. 70-77
-
-
Kar, S.1
Fan, J.2
Smith, M.J.3
Goedert, M.4
Amos, L.A.5
-
67
-
-
0029063397
-
Structure of tubulin at 6.5 A and location of the taxolbinding site
-
Nogales E, Wolf SG, Khan IA, Luduena RF, Downing KH (1995) Structure of tubulin at 6.5 A and location of the taxolbinding site. Nature 375, 424-427.
-
(1995)
Nature
, vol.375
, pp. 424-427
-
-
Nogales, E.1
Wolf, S.G.2
Khan, I.A.3
Luduena, R.F.4
Downing, K.H.5
-
68
-
-
77958065504
-
Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy
-
Brunden KR, Zhang B, Carroll J, Yao Y, Potuzak JS, Hogan A-ML, Iba M, James MJ, Xie SX, Ballatore C, Smith AB, Lee VM-Y, Trojanowski JQ (2010) Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy. J Neurosci 30, 13861-13866.
-
(2010)
J Neurosci
, vol.30
, pp. 13861-13866
-
-
Brunden, K.R.1
Zhang, B.2
Carroll, J.3
Yao, Y.4
Potuzak, J.S.5
Hogan, A.-M.L.6
Iba, M.7
James, M.J.8
Xie, S.X.9
Ballatore, C.10
Smith, A.B.11
Lee, V.M.-Y.12
Trojanowski, J.Q.13
-
69
-
-
84863230105
-
The microtubule-stabilizing agent, epothilone d, reduces axonal dysfunction, neurotoxicity, cognitive deficits, and Alzheimer-like pathology in an interventional study with aged tau transgenic mice
-
Zhang B, Carroll J, Trojanowski JQ, Yao Y, Iba M, Potuzak JS, Hogan A-ML, Xie SX, Ballatore C, Smith AB, Lee VM-Y, Brunden KR (2012) The microtubule-stabilizing agent, epothilone d, reduces axonal dysfunction, neurotoxicity, cognitive deficits, and Alzheimer-like pathology in an interventional study with aged tau transgenic mice. J Neurosci 32, 3601-3611.
-
(2012)
J Neurosci
, vol.32
, pp. 3601-3611
-
-
Zhang, B.1
Carroll, J.2
Trojanowski, J.Q.3
Yao, Y.4
Iba, M.5
Potuzak, J.S.6
Hogan, A.-M.L.7
Xie, S.X.8
Ballatore, C.9
Smith, A.B.10
Lee, V.M.-Y.11
Brunden, K.R.12
|