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Volumn 41, Issue 3, 2014, Pages 268-275

68Ga-DOTA-NGR as a novel molecular probe for APN-positive tumor imaging using MicroPET

Author keywords

68Ga labeling; APN; CD13; NGR peptide; Tumor angiogenesis

Indexed keywords

1,4,7,10-TETRAAZACYCLODODECANE- 1,4,7,10-TETRAACETIC ACID; DIAGNOSTIC AGENT; GALLIUM; MICROSOMAL AMINOPEPTIDASE; NGR PEPTIDE; OLIGOPEPTIDE; SINGLE HETEROCYCLIC RINGS; TETRAXETAN;

EID: 84893904761     PISSN: 09698051     EISSN: 18729614     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2013.12.008     Document Type: Article
Times cited : (31)

References (37)
  • 1
    • 0024518875 scopus 로고
    • Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N
    • Look A.T., Ashmun R.A., Shapiro L.H., Peiper S.C. Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N. J Clin Invest 1989, 83:1299-1307.
    • (1989) J Clin Invest , vol.83 , pp. 1299-1307
    • Look, A.T.1    Ashmun, R.A.2    Shapiro, L.H.3    Peiper, S.C.4
  • 2
    • 0034473056 scopus 로고    scopus 로고
    • Structure and function of aminopeptidase N
    • Sjostrom H., Noren O., Olsen J. Structure and function of aminopeptidase N. Adv Exp Med Biol 2000, 477:25-34.
    • (2000) Adv Exp Med Biol , vol.477 , pp. 25-34
    • Sjostrom, H.1    Noren, O.2    Olsen, J.3
  • 3
    • 33746080895 scopus 로고    scopus 로고
    • Clinical significance of aminopeptidase N in non-small cell lung cancer
    • Tokuhara T., Hattori N., Ishida H., et al. Clinical significance of aminopeptidase N in non-small cell lung cancer. Clin Cancer Res 2006, 12:3971-3978.
    • (2006) Clin Cancer Res , vol.12 , pp. 3971-3978
    • Tokuhara, T.1    Hattori, N.2    Ishida, H.3
  • 4
    • 0036161112 scopus 로고    scopus 로고
    • Aminopeptidase N is involved in cell motility and angiogenesis: its clinical significance in human colon cancer
    • Hashida H., Takabayashi A., Kanai M., et al. Aminopeptidase N is involved in cell motility and angiogenesis: its clinical significance in human colon cancer. Gastroenterology 2002, 122:376-386.
    • (2002) Gastroenterology , vol.122 , pp. 376-386
    • Hashida, H.1    Takabayashi, A.2    Kanai, M.3
  • 5
    • 0035314018 scopus 로고    scopus 로고
    • Aminopeptidase N regulated by zinc in human prostate participates in tumor cell invasion
    • Ishii K., Usui S., Sugimura Y., et al. Aminopeptidase N regulated by zinc in human prostate participates in tumor cell invasion. Int J Cancer 2001, 92:49-54.
    • (2001) Int J Cancer , vol.92 , pp. 49-54
    • Ishii, K.1    Usui, S.2    Sugimura, Y.3
  • 7
    • 0027195127 scopus 로고
    • Role of aminopeptidase N (CD13) in tumor-cell invasion and extracellular matrix degradation
    • Saiki I., Fujii H., Yoneda J., et al. Role of aminopeptidase N (CD13) in tumor-cell invasion and extracellular matrix degradation. Int J Cancer 1993, 54:137-143.
    • (1993) Int J Cancer , vol.54 , pp. 137-143
    • Saiki, I.1    Fujii, H.2    Yoneda, J.3
  • 8
    • 0029100416 scopus 로고
    • Human melanoma invasion and metastasis enhancement by high expression of aminopeptidase N/CD13
    • Fujii H., Nakajima M., Saiki I., Yoneda J., Azuma I., Tsuruo T. Human melanoma invasion and metastasis enhancement by high expression of aminopeptidase N/CD13. Clin Exp Metastasis 1995, 13:337-344.
    • (1995) Clin Exp Metastasis , vol.13 , pp. 337-344
    • Fujii, H.1    Nakajima, M.2    Saiki, I.3    Yoneda, J.4    Azuma, I.5    Tsuruo, T.6
  • 9
    • 0032535999 scopus 로고    scopus 로고
    • Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model
    • Arap W., Pasqualini R., Ruoslahti E. Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. Science 1998, 279:377-380.
    • (1998) Science , vol.279 , pp. 377-380
    • Arap, W.1    Pasqualini, R.2    Ruoslahti, E.3
  • 10
    • 84863285169 scopus 로고    scopus 로고
    • NGR-based strategies for targeting delivery of chemotherapeutics to tumor vasculature
    • Zou M., Zhang L., Xie Y., Xu W. NGR-based strategies for targeting delivery of chemotherapeutics to tumor vasculature. Anticancer Agents Med Chem 2012, 12:239-246.
    • (2012) Anticancer Agents Med Chem , vol.12 , pp. 239-246
    • Zou, M.1    Zhang, L.2    Xie, Y.3    Xu, W.4
  • 11
    • 79951822182 scopus 로고    scopus 로고
    • Tumor vasculature targeting through NGR peptide-based drug delivery systems
    • Corti A., Curnis F. Tumor vasculature targeting through NGR peptide-based drug delivery systems. Curr Pharm Biotechnol 2011, 12:1128-1134.
    • (2011) Curr Pharm Biotechnol , vol.12 , pp. 1128-1134
    • Corti, A.1    Curnis, F.2
  • 13
    • 79953329168 scopus 로고    scopus 로고
    • Two doses of NGR-hTNF in combination with capecitabine plus oxaliplatin in colorectal cancer patients failing standard therapies
    • Mammoliti S., Andretta V., Bennicelli E., et al. Two doses of NGR-hTNF in combination with capecitabine plus oxaliplatin in colorectal cancer patients failing standard therapies. Ann Oncol 2011, 22:973-978.
    • (2011) Ann Oncol , vol.22 , pp. 973-978
    • Mammoliti, S.1    Andretta, V.2    Bennicelli, E.3
  • 14
    • 79953306455 scopus 로고    scopus 로고
    • Phase I study of NGR-hTNF, a selective vascular targeting agent, in combination with cisplatin in refractory solid tumors
    • Gregorc V., De Braud F.G., De Pas T.M., et al. Phase I study of NGR-hTNF, a selective vascular targeting agent, in combination with cisplatin in refractory solid tumors. Clin Cancer Res 2011, 17:1964-1972.
    • (2011) Clin Cancer Res , vol.17 , pp. 1964-1972
    • Gregorc, V.1    De Braud, F.G.2    De Pas, T.M.3
  • 15
    • 67650638995 scopus 로고    scopus 로고
    • Phase Ib study of NGR-hTNF, a selective vascular targeting agent, administered at low doses in combination with doxorubicin to patients with advanced solid tumours
    • Gregorc V., Santoro A., Bennicelli E., et al. Phase Ib study of NGR-hTNF, a selective vascular targeting agent, administered at low doses in combination with doxorubicin to patients with advanced solid tumours. Br J Cancer 2009, 101:219-224.
    • (2009) Br J Cancer , vol.101 , pp. 219-224
    • Gregorc, V.1    Santoro, A.2    Bennicelli, E.3
  • 16
    • 84872616128 scopus 로고    scopus 로고
    • Phase I and pharmacodynamic study of high-dose NGR-hTNF in patients with refractory solid tumours
    • Zucali P.A., Simonelli M., De Vincenzo F., et al. Phase I and pharmacodynamic study of high-dose NGR-hTNF in patients with refractory solid tumours. Br J Cancer 2013, 108:58-63.
    • (2013) Br J Cancer , vol.108 , pp. 58-63
    • Zucali, P.A.1    Simonelli, M.2    De Vincenzo, F.3
  • 17
    • 44849126076 scopus 로고    scopus 로고
    • In vivo optical imaging of CD13/APN-expression in tumor xenografts
    • von Wallbrunn A., Waldeck J., Höltke C., et al. In vivo optical imaging of CD13/APN-expression in tumor xenografts. J Biomed Opt 2008, 13:011007.
    • (2008) J Biomed Opt , vol.13 , pp. 011007
    • von Wallbrunn, A.1    Waldeck, J.2    Höltke, C.3
  • 18
    • 33751173632 scopus 로고    scopus 로고
    • CNGR: a novel homing sequence for CD13/APN targeted molecular imaging of murine cardiac angiogenesis in vivo
    • Buehler A., van Zandvoort M.A., Stelt B.J., et al. cNGR: a novel homing sequence for CD13/APN targeted molecular imaging of murine cardiac angiogenesis in vivo. Arterioscler Thromb Vasc Biol 2006, 26:2681-2687.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 2681-2687
    • Buehler, A.1    van Zandvoort, M.A.2    Stelt, B.J.3
  • 19
    • 77149180381 scopus 로고    scopus 로고
    • Molecular magnetic resonance imaging of myocardial angiogenesis after acute myocardial infarction
    • Oostendorp M., Douma K., Wagenaar A., et al. Molecular magnetic resonance imaging of myocardial angiogenesis after acute myocardial infarction. Circulation 2010, 121:775-783.
    • (2010) Circulation , vol.121 , pp. 775-783
    • Oostendorp, M.1    Douma, K.2    Wagenaar, A.3
  • 20
    • 54749156335 scopus 로고    scopus 로고
    • Quantitative molecular magnetic resonance imaging of tumor angiogenesis using cNGR-labeled paramagnetic quantum dots
    • Oostendorp M., Douma K., Hackeng T.M., et al. Quantitative molecular magnetic resonance imaging of tumor angiogenesis using cNGR-labeled paramagnetic quantum dots. Cancer Res 2008, 68:7676-7683.
    • (2008) Cancer Res , vol.68 , pp. 7676-7683
    • Oostendorp, M.1    Douma, K.2    Hackeng, T.M.3
  • 21
    • 84872125690 scopus 로고    scopus 로고
    • Synthesis and evaluation of 64Cu-labeled monomeric and dimeric NGR peptides for microPET imaging of CD13 receptor expression
    • Chen K., Ma W., Li G., et al. Synthesis and evaluation of 64Cu-labeled monomeric and dimeric NGR peptides for microPET imaging of CD13 receptor expression. Mol Pharm 2013, 10:417-427.
    • (2013) Mol Pharm , vol.10 , pp. 417-427
    • Chen, K.1    Ma, W.2    Li, G.3
  • 22
    • 84876672361 scopus 로고    scopus 로고
    • (99m)Tc-labeled monomeric and dimeric NGR peptides for SPECT imaging of CD13 receptor in tumor-bearing mice
    • Ma W., Kang F., Wang Z., et al. (99m)Tc-labeled monomeric and dimeric NGR peptides for SPECT imaging of CD13 receptor in tumor-bearing mice. Amino Acids 2013, 44:1337-1345.
    • (2013) Amino Acids , vol.44 , pp. 1337-1345
    • Ma, W.1    Kang, F.2    Wang, Z.3
  • 23
    • 77950948813 scopus 로고    scopus 로고
    • Evading tumor evasion: current concepts and perspectives of anti-angiogenic cancer therapy
    • Abdollahi A., Folkman J. Evading tumor evasion: current concepts and perspectives of anti-angiogenic cancer therapy. Drug Resist Updat 2010, 13:16-28.
    • (2010) Drug Resist Updat , vol.13 , pp. 16-28
    • Abdollahi, A.1    Folkman, J.2
  • 24
    • 33947732977 scopus 로고    scopus 로고
    • Angiogenesis: an organizing principle for drug discovery?
    • Folkman J. Angiogenesis: an organizing principle for drug discovery?. Nat Rev Drug Discov 2007, 6:273-286.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 273-286
    • Folkman, J.1
  • 25
    • 84863743045 scopus 로고    scopus 로고
    • Radiolabeled RGD peptides as integrin alpha(v)beta3-targeted PET tracers
    • Tateishi U., Oka T., Inoue T. Radiolabeled RGD peptides as integrin alpha(v)beta3-targeted PET tracers. Curr Med Chem 2012, 19:3301-3309.
    • (2012) Curr Med Chem , vol.19 , pp. 3301-3309
    • Tateishi, U.1    Oka, T.2    Inoue, T.3
  • 26
    • 72449156995 scopus 로고    scopus 로고
    • Radiolabeled cyclic RGD peptides as integrin alpha(v)beta(3)-targeted radiotracers: maximizing binding affinity via bivalency
    • Liu S. Radiolabeled cyclic RGD peptides as integrin alpha(v)beta(3)-targeted radiotracers: maximizing binding affinity via bivalency. Bioconjug Chem 2009, 20:2199-2213.
    • (2009) Bioconjug Chem , vol.20 , pp. 2199-2213
    • Liu, S.1
  • 27
    • 63849300752 scopus 로고    scopus 로고
    • Application of RGD-containing peptides as imaging probes for alphavbeta3 expression
    • Dijkgraaf I., Beer A.J., Wester H.J. Application of RGD-containing peptides as imaging probes for alphavbeta3 expression. Front Biosci 2009, 14:887-899.
    • (2009) Front Biosci , vol.14 , pp. 887-899
    • Dijkgraaf, I.1    Beer, A.J.2    Wester, H.J.3
  • 28
    • 33749449024 scopus 로고    scopus 로고
    • Aminopeptidase N (APN/CD13) is selectively expressed in vascular endothelial cells and plays multiple roles in angiogenesis
    • Fukasawa K., Fujii H., Saitoh Y., et al. Aminopeptidase N (APN/CD13) is selectively expressed in vascular endothelial cells and plays multiple roles in angiogenesis. Cancer Lett 2006, 243:135-143.
    • (2006) Cancer Lett , vol.243 , pp. 135-143
    • Fukasawa, K.1    Fujii, H.2    Saitoh, Y.3
  • 29
    • 0033950895 scopus 로고    scopus 로고
    • Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis
    • Pasqualini R., Koivunen E., Kain R., et al. Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis. Cancer Res 2000, 60:722-727.
    • (2000) Cancer Res , vol.60 , pp. 722-727
    • Pasqualini, R.1    Koivunen, E.2    Kain, R.3
  • 30
    • 27744555535 scopus 로고    scopus 로고
    • Aminopeptidase N/CD13 targeting fluorescent probes: synthesis and application to tumor cell imaging
    • Zhang Z., Harada H., Tanabe K., Hatta H., Hiraoka M., Nishimoto S. Aminopeptidase N/CD13 targeting fluorescent probes: synthesis and application to tumor cell imaging. Peptides 2005, 26:2182-2187.
    • (2005) Peptides , vol.26 , pp. 2182-2187
    • Zhang, Z.1    Harada, H.2    Tanabe, K.3    Hatta, H.4    Hiraoka, M.5    Nishimoto, S.6
  • 31
    • 84861012001 scopus 로고    scopus 로고
    • Modification of cyclic NGR tumor neovasculature-homing motif sequence to human plasminogen kringle 5 improves inhibition of tumor growth
    • Jiang W., Jin G., Ma D., et al. Modification of cyclic NGR tumor neovasculature-homing motif sequence to human plasminogen kringle 5 improves inhibition of tumor growth. PLoS ONE 2012, 7:e37132.
    • (2012) PLoS ONE , vol.7
    • Jiang, W.1    Jin, G.2    Ma, D.3
  • 32
    • 44249106830 scopus 로고    scopus 로고
    • 68Ga-PET: a powerful generator-based alternative to cyclotron-based PET radiopharmaceuticals
    • Fani M., Andre J.P., Maecke H.R. 68Ga-PET: a powerful generator-based alternative to cyclotron-based PET radiopharmaceuticals. Contrast Media Mol Imaging 2008, 3:67-77.
    • (2008) Contrast Media Mol Imaging , vol.3 , pp. 67-77
    • Fani, M.1    Andre, J.P.2    Maecke, H.R.3
  • 33
    • 35348815609 scopus 로고    scopus 로고
    • Processing of generator-produced 68Ga for medical application
    • Zhernosekov K.P., Filosofov D.V., Baum R.P., et al. Processing of generator-produced 68Ga for medical application. J Nucl Med 2007, 48:1741-1748.
    • (2007) J Nucl Med , vol.48 , pp. 1741-1748
    • Zhernosekov, K.P.1    Filosofov, D.V.2    Baum, R.P.3
  • 34
    • 79957690379 scopus 로고    scopus 로고
    • (68)Ga-labeled DOTA-peptides and (68)Ga-labeled radiopharmaceuticals for positron emission tomography: current status of research, clinical applications, and future perspectives
    • Breeman W.A.P., de Blois E., Sze Chan H., Konijnenberg M., Kwekkeboom D.J., Krenning E.P. (68)Ga-labeled DOTA-peptides and (68)Ga-labeled radiopharmaceuticals for positron emission tomography: current status of research, clinical applications, and future perspectives. Semin Nucl Med 2011, 41:314-321.
    • (2011) Semin Nucl Med , vol.41 , pp. 314-321
    • Breeman, W.A.P.1    de Blois, E.2    Sze Chan, H.3    Konijnenberg, M.4    Kwekkeboom, D.J.5    Krenning, E.P.6
  • 35
    • 77957978634 scopus 로고    scopus 로고
    • The renaissance of the (68)Ge/(68)Ga radionuclide generator initiates new developments in (68)Ga radiopharmaceutical chemistry
    • Roesch F., Riss P.J. The renaissance of the (68)Ge/(68)Ga radionuclide generator initiates new developments in (68)Ga radiopharmaceutical chemistry. Curr Top Med Chem 2010, 10:1633-1668.
    • (2010) Curr Top Med Chem , vol.10 , pp. 1633-1668
    • Roesch, F.1    Riss, P.J.2
  • 36
    • 78649354736 scopus 로고    scopus 로고
    • Procedure guidelines for PET/CT tumour imaging with 68Ga-DOTA-conjugated peptides: 68Ga-DOTA-TOC, 68Ga-DOTA-NOC, 68Ga-DOTA-TATE
    • Virgolini I., Ambrosini V., Bomanji J.B., et al. Procedure guidelines for PET/CT tumour imaging with 68Ga-DOTA-conjugated peptides: 68Ga-DOTA-TOC, 68Ga-DOTA-NOC, 68Ga-DOTA-TATE. Eur J Nucl Med Mol Imaging 2010, 37:2004-2010.
    • (2010) Eur J Nucl Med Mol Imaging , vol.37 , pp. 2004-2010
    • Virgolini, I.1    Ambrosini, V.2    Bomanji, J.B.3
  • 37
    • 27944457471 scopus 로고    scopus 로고
    • MicroPET imaging of glioma integrin αvβ3 expression using (64)Cu-labeled tetrameric RGD peptide
    • Wu Y., Zhang X., Xiong Z., et al. microPET imaging of glioma integrin αvβ3 expression using (64)Cu-labeled tetrameric RGD peptide. J Nucl Med 2005, 46:1707-1718.
    • (2005) J Nucl Med , vol.46 , pp. 1707-1718
    • Wu, Y.1    Zhang, X.2    Xiong, Z.3


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