How to determine the size of folding nuclei of protofibrils from the concentration dependence of the rate and lag-time of Aggregation. II. Experimental application for insulin and LysPro insulin: Aggregation morphology, kinetics, and sizes of nuclei

Journal of Physical Chemistry B

Volumn 118, Issue 5, 2014, Pages 1198-1206

  Selivanova, Olga M ^a   Suvorina, Maria Yu ^a   Dovidchenko, Nikita V ^a   Eliseeva, Irina A ^a   Surin, Alexey K ^a,c   Finkelstein, Alexey V ^a,b   Schmatchenko, Vadim V ^a   Galzitskaya, Oxana V ^a  

^a INSTITUTE OF PROTEIN RESEARCH   (Russian Federation)

^b MOSCOW STATE UNIVERSITY   (Russian Federation)

^c STATE RESEARCH CENTER FOR APPLIED MICROBIOLOGY AND BIOTECHNOLOGY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

AGGREGATION MORPHOLOGY; CONCENTRATION DEPENDENCE; EXPERIMENTAL APPLICATION; EXPONENTIAL GROWTH; FLUORESCENCE ASSAY; LOW CONCENTRATIONS; THEORETICAL MODELING; X-RAY DIFFRACTION METHOD;

GLYCOPROTEINS; MONOMERS; MORPHOLOGY; X RAY DIFFRACTION;

INSULIN;

AMYLOID; INSULIN; INSULIN LISPRO; RECOMBINANT PROTEIN;

ARTICLE; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; KINETICS; METABOLISM; PARTICLE SIZE; PROTEIN FOLDING; PROTEIN TERTIARY STRUCTURE;

AMYLOID; HUMANS; INSULIN; INSULIN LISPRO; KINETICS; MODELS, MOLECULAR; PARTICLE SIZE; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS;

EID: 84893867894     PISSN: 15206106     EISSN: 15205207     Source Type: Journal    
DOI: 10.1021/jp4083568     Document Type: Article

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