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Volumn 33, Issue 3, 2014, Pages 581-588

Revealing the molecular mechanism of colorectal cancer by establishing LGALS3-related protein-protein interaction network and identifying signaling pathways

Author keywords

Colorectal cancer; Differentially expressed genes; Gene ontology analysis; Protein protein interaction network; Signaling pathway

Indexed keywords

COLORECTAL NEOPLASMS; GALECTIN 3; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE REGULATORY NETWORKS; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN INTERACTION MAPS; SIGNAL TRANSDUCTION;

EID: 84893867170     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2014.1620     Document Type: Article
Times cited : (10)

References (47)
  • 2
    • 77951879165 scopus 로고    scopus 로고
    • Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: A multicentre randomised controlled trial
    • Atkin WS, Edwards R, Kralj-Hans I, et al: Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: A multicentre randomised controlled trial. Lancet 375: 1624-1633, 2010.
    • (2010) Lancet , vol.375 , pp. 1624-1633
    • Atkin, W.S.1    Edwards, R.2    Kralj-Hans, I.3
  • 3
    • 53049087109 scopus 로고    scopus 로고
    • Genomic and epigenetic instability in colorectal cancer pathogenesis
    • Grady WM and Carethers JM: Genomic and epigenetic instability in colorectal cancer pathogenesis. Gastroenterology 135: 1079-1099, 2008.
    • (2008) Gastroenterology , vol.135 , pp. 1079-1099
    • Grady, W.M.1    Carethers, J.M.2
  • 4
    • 77951647898 scopus 로고    scopus 로고
    • Role of the serrated pathway in colorectal cancer pathogenesis
    • Leggett B and Whitehall V: Role of the serrated pathway in colorectal cancer pathogenesis. Gastroenterology 138: 2088-2100, 2010.
    • (2010) Gastroenterology , vol.138 , pp. 2088-2100
    • Leggett, B.1    Whitehall, V.2
  • 6
    • 35748967324 scopus 로고    scopus 로고
    • MRNA/microRNA gene expression profile in microsatellite unstable colorectal cancer
    • Lanza G, Ferracin M, Gafa R, et al: MRNA/microRNA gene expression profile in microsatellite unstable colorectal cancer. Mol Cancer 6: 54, 2007.
    • (2007) Mol Cancer , vol.6 , pp. 54
    • Lanza, G.1    Ferracin, M.2    Gafa, R.3
  • 7
    • 52149123619 scopus 로고    scopus 로고
    • Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
    • Jones S, Zhang X, Parsons DW, et al: Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 321: 1801-1806, 2008.
    • (2008) Science , vol.321 , pp. 1801-1806
    • Jones, S.1    Zhang, X.2    Parsons, D.W.3
  • 8
    • 0037778008 scopus 로고    scopus 로고
    • The Wnt signaling pathway and its role in tumor development
    • Lustig B and Behrens J: The Wnt signaling pathway and its role in tumor development. J Cancer Res Clin Oncol 129: 199-221, 2003.
    • (2003) J Cancer Res Clin Oncol , vol.129 , pp. 199-221
    • Lustig, B.1    Behrens, J.2
  • 10
    • 80051975232 scopus 로고    scopus 로고
    • Targeting SP1 transcription factor in prostate cancer therapy
    • Sankpal UT, Goodison S, Abdelrahim M and Basha R: Targeting SP1 transcription factor in prostate cancer therapy. Med Chem 7: 518-525, 2011.
    • (2011) Med Chem , vol.7 , pp. 518-525
    • Sankpal, U.T.1    Goodison, S.2    Abdelrahim, M.3    Basha, R.4
  • 11
    • 27344451557 scopus 로고    scopus 로고
    • Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
    • Tomlins SA, Rhodes DR, Perner S, et al: Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science 310: 644-648, 2005.
    • (2005) Science , vol.310 , pp. 644-648
    • Tomlins, S.A.1    Rhodes, D.R.2    Perner, S.3
  • 12
    • 33646435815 scopus 로고    scopus 로고
    • KLF4 and KLF5 regulate proliferation, apoptosis and invasion in esophageal cancer cells
    • Yang Y, Goldstein BG, Chao HH and Katz JP: KLF4 and KLF5 regulate proliferation, apoptosis and invasion in esophageal cancer cells. Cancer Biol Ther 4: 1216-1221, 2005.
    • (2005) Cancer Biol Ther , vol.4 , pp. 1216-1221
    • Yang, Y.1    Goldstein, B.G.2    Chao, H.H.3    Katz, J.P.4
  • 15
    • 0031928731 scopus 로고    scopus 로고
    • Metastasis of human colon cancer is altered by modifying expression of the β-galactoside-binding protein galectin 3
    • Bresalier RS, Mazurek N, Sternberg LR, et al: Metastasis of human colon cancer is altered by modifying expression of the β-galactoside-binding protein galectin 3. Gastroenterology 115: 287-296, 1998.
    • (1998) Gastroenterology , vol.115 , pp. 287-296
    • Bresalier, R.S.1    Mazurek, N.2    Sternberg, L.R.3
  • 16
    • 70149097554 scopus 로고    scopus 로고
    • Circulating galectin-3 promotes metastasis by modifying MUC1 localization on cancer cell surface
    • Zhao Q, Guo X, Nash GB, et al: Circulating galectin-3 promotes metastasis by modifying MUC1 localization on cancer cell surface. Cancer Res 69: 6799-6806, 2009.
    • (2009) Cancer Res , vol.69 , pp. 6799-6806
    • Zhao, Q.1    Guo, X.2    Nash, G.B.3
  • 17
    • 77953627018 scopus 로고    scopus 로고
    • Research interaction between circulating galectin-3 and cancer-associated MUC1 enhances tumour cell homotypic aggregation and prevents anoikis
    • Zhao Q, Barclay M, Hilkens J, et al: Research interaction between circulating galectin-3 and cancer-associated MUC1 enhances tumour cell homotypic aggregation and prevents anoikis. Mol Cancer 9: 154, 2010.
    • (2010) Mol Cancer , vol.9 , pp. 154
    • Zhao, Q.1    Barclay, M.2    Hilkens, J.3
  • 18
    • 0142121516 scopus 로고    scopus 로고
    • Exploration, normalization, and summaries of high density oligonucleotide array probe level data
    • Irizarry RA, Hobbs B, Collin F, et al: Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4: 249-264, 2003.
    • (2003) Biostatistics , vol.4 , pp. 249-264
    • Irizarry, R.A.1    Hobbs, B.2    Collin, F.3
  • 19
    • 0035942271 scopus 로고    scopus 로고
    • Significance analysis of microarrays applied to the ionizing radiation response
    • Tusher VG, Tibshirani R and Chu G: Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci USA 98: 5116-5121, 2001.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5116-5121
    • Tusher, V.G.1    Tibshirani, R.2    Chu, G.3
  • 20
    • 0346801873 scopus 로고    scopus 로고
    • The gene ontology (GO) database and informatics resource
    • Harris M, Clark J, Ireland A, et al: The gene ontology (GO) database and informatics resource. Nucleic Acids Res 32: D258-D261, 2004.
    • (2004) Nucleic Acids Res , vol.32
    • Harris, M.1    Clark, J.2    Ireland, A.3
  • 21
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
    • Huang da W, Sherman BT and Lempicki RA: Systematic and integrative analysis of large gene lists using DAVID bioinfor-matics resources. Nat Protoc 4: 44-57, 2008.
    • (2008) Nat Protoc , vol.4 , pp. 44-57
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 22
    • 58049215467 scopus 로고    scopus 로고
    • A novel signaling pathway impact analysis
    • Tarca AL, Draghici S, Khatri P, et al: A novel signaling pathway impact analysis. Bioinformatics 25: 75-82, 2009.
    • (2009) Bioinformatics , vol.25 , pp. 75-82
    • Tarca, A.L.1    Draghici, S.2    Khatri, P.3
  • 23
    • 77954364953 scopus 로고    scopus 로고
    • Transcription factor regulation can be accurately predicted from the presence of target gene signatures in microarray gene expression data
    • Essaghir A, Toffalini F, Knoops L, Kallin A, van Helden J and Demoulin JB: Transcription factor regulation can be accu-rately predicted from the presence of target gene signatures in microarray gene expression data. Nucleic Acids Res 38: E120, 2010.
    • (2010) Nucleic Acids Res , vol.38
    • Essaghir, A.1    Toffalini, F.2    Knoops, L.3    Kallin, A.4    Van Helden, J.5    Demoulin, J.B.6
  • 25
    • 79952202448 scopus 로고    scopus 로고
    • Cytoscape: Software for visualization and analysis of biological networks
    • Hamacher M Eisenacher M and Stephan C (eds.). Humana Press.
    • Kohl M, Wiese S and Warscheid B: Cytoscape: Software for visualization and analysis of biological networks. In: Data Mining in Proteomics. Hamacher M Eisenacher M and Stephan C (eds.). Humana Press. pp291-303, 2011.
    • (2011) Data Mining in Proteomics. , pp. 291-303
    • Kohl, M.1    Wiese, S.2    Warscheid, B.3
  • 26
    • 33746851956 scopus 로고    scopus 로고
    • Tumor metastasis: Mechanistic insights and clinical challenges
    • Steeg PS: Tumor metastasis: Mechanistic insights and clinical challenges. Nat Med 12: 895-904, 2006.
    • (2006) Nat Med , vol.12 , pp. 895-904
    • Steeg, P.S.1
  • 27
    • 30544438805 scopus 로고    scopus 로고
    • Polymorphisms of the AURKA (STK15/Aurora Kinase) gene and breast cancer risk (United States)
    • Cox DG, Hankinson SE and Hunter DJ: Polymorphisms of the AURKA (STK15/Aurora Kinase) gene and breast cancer risk (United States). Cancer Causes Control 17: 81-83, 2006.
    • (2006) Cancer Causes Control , vol.17 , pp. 81-83
    • Cox, D.G.1    Hankinson, S.E.2    Hunter, D.J.3
  • 28
    • 34447498739 scopus 로고    scopus 로고
    • AURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: A consortium of investigators of modifiers of BRCA1/2 study
    • Couch FJ, Sinilnikova O, Vierkant RA, et al: AURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: A consortium of investigators of modifiers of BRCA1/2 study. Cancer Epidemiol Biomarkers Prev 16: 1416-1421, 2007.
    • (2007) Cancer Epidemiol Biomarkers Prev , vol.16 , pp. 1416-1421
    • Couch, F.J.1    Sinilnikova, O.2    Vierkant, R.A.3
  • 29
    • 33645828238 scopus 로고    scopus 로고
    • Significance of pituitary tumor transforming gene 1 (PTTG1) in prostate cancer
    • Zhu X, Mao Z, Na Y, Guo Y, Wang X and Xin D: Significance of pituitary tumor transforming gene 1 (PTTG1) in prostate cancer. Anticancer Res 26: 1253-1259, 2006.
    • (2006) Anticancer Res , vol.26 , pp. 1253-1259
    • Zhu, X.1    Mao, Z.2    Na, Y.3    Guo, Y.4    Wang, X.5    Xin, D.6
  • 30
    • 80455176998 scopus 로고    scopus 로고
    • Structural and functional insights into a dodecameric molecular machine - The RuvBL1/RuvBL2 complex
    • Gorynia S, Bandeiras TM, Pinho FG, et al: Structural and functional insights into a dodecameric molecular machine-the RuvBL1/RuvBL2 complex. J Struct Biol 176: 279-291, 2011.
    • (2011) J Struct Biol , vol.176 , pp. 279-291
    • Gorynia, S.1    Bandeiras, T.M.2    Pinho, F.G.3
  • 31
    • 85133405634 scopus 로고    scopus 로고
    • Bladder filling and voiding affect umbrella cell tight junction organization and function
    • Jul, Epub ahead of print)
    • Carattino MD, Prakasam HS, Ruiz WG, et al: Bladder filling and voiding affect umbrella cell tight junction organization and function. Am J Physiol Renal Physiol: Jul 24, 2013 (Epub ahead of print).
    • (2013) Am J Physiol Renal Physiol , vol.24
    • Carattino, M.D.1    Prakasam, H.S.2    Ruiz, W.G.3
  • 32
    • 58149141898 scopus 로고    scopus 로고
    • Claudin-7 and claudin-8: Immunohistochemical markers for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma
    • Osunkoya AO, Cohen C, Lawson D, Picken MM, Amin MB and Young AN: Claudin-7 and claudin-8: Immunohistochemical markers for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma. Hum Pathol 40: 206-210, 2009.
    • (2009) Hum Pathol , vol.40 , pp. 206-210
    • Osunkoya, A.O.1    Cohen, C.2    Lawson, D.3    Picken, M.M.4    Amin, M.B.5    Young, A.N.6
  • 33
    • 0842346045 scopus 로고    scopus 로고
    • CLDN23 gene, frequently down-regulated in intestinal-type gastric cancer, is a novel member of CLAUDIN gene family
    • Katoh M and Katoh M: CLDN23 gene, frequently down-regulated in intestinal-type gastric cancer, is a novel member of CLAUDIN gene family. Int J Mol Med 11: 683-689, 2003.
    • (2003) Int J Mol Med , vol.11 , pp. 683-689
    • Katoh, M.1    Katoh, M.2
  • 34
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • Vogelstein B and Kinzler KW: Cancer genes and the pathways they control. Nat Med 10: 789-799, 2004.
    • (2004) Nat Med , vol.10 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 35
    • 60749109846 scopus 로고    scopus 로고
    • Cell cycle, CDKs and cancer: A changing paradigm
    • Malumbres M and Barbacid M: Cell cycle, CDKs and cancer: A changing paradigm. Nat Rev Cancer 9: 153-166, 2009.
    • (2009) Nat Rev Cancer , vol.9 , pp. 153-166
    • Malumbres, M.1    Barbacid, M.2
  • 36
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr CJ: Cancer cell cycles. Science 274: 1672-1677, 1996.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 37
    • 84865268664 scopus 로고    scopus 로고
    • TRAF family member-associated NF-?B activator (TANK) is a negative regulator of osteoclastogenesis and bone formation
    • Maruyama K, Kawagoe T, Kondo T, Akira S and Takeuchi O: TRAF family member-associated NF-?B activator (TANK) is a negative regulator of osteoclastogenesis and bone formation. J Biol Chem 287: 29114-29124, 2012.
    • (2012) J Biol Chem , vol.287 , pp. 29114-29124
    • Maruyama, K.1    Kawagoe, T.2    Kondo, T.3    Akira, S.4    Takeuchi, O.5
  • 38
    • 0031172065 scopus 로고    scopus 로고
    • NF-?B: A crucial transcription factor for glial and neuronal cell function
    • O'neill LA and Kaltschmidt C: NF-?B: A crucial transcription factor for glial and neuronal cell function. Trends Neurosci 20: 252-258, 1997.
    • (1997) Trends Neurosci , vol.20 , pp. 252-258
    • O'neill, L.A.1    Kaltschmidt, C.2
  • 40
    • 34548536941 scopus 로고    scopus 로고
    • Nuclear factor-?B tumor expression predicts response and survival in irinotecan-refractory metastatic colorectal cancer treated with cetuximab-irinotecan therapy
    • Scartozzi M, Bearzi I, Pierantoni C, et al: Nuclear factor-?B tumor expression predicts response and survival in irinotecan-refractory metastatic colorectal cancer treated with cetuximab-irinotecan therapy. J Clin Oncol 25: 3930-3935, 2007.
    • (2007) J Clin Oncol , vol.25 , pp. 3930-3935
    • Scartozzi, M.1    Bearzi, I.2    Pierantoni, C.3
  • 41
    • 0036782706 scopus 로고    scopus 로고
    • Transcription factors as targets for cancer therapy
    • Darnell JE Jr: Transcription factors as targets for cancer therapy. Nat Rev Cancer 2: 740-749, 2002.
    • (2002) Nat Rev Cancer , vol.2 , pp. 740-749
    • Darnell Jr., J.E.1
  • 42
    • 0141765653 scopus 로고    scopus 로고
    • Quantitation of MYC gene expression in sporadic breast tumors with a real-time reverse transcription-PCR assay
    • Bièche I, Laurendeau I, Tozlu S, et al: Quantitation of MYC gene expression in sporadic breast tumors with a real-time reverse transcription-PCR assay. Cancer Res 59: 2759-2765, 1999.
    • (1999) Cancer Res , vol.59 , pp. 2759-2765
    • Bièche, I.1    Laurendeau, I.2    Tozlu, S.3
  • 43
    • 11244298718 scopus 로고    scopus 로고
    • The proinvasive activity of Wnt-2 is mediated through a noncanonical Wnt pathway coupled to GSK-3β and c-Jun/AP-1 signaling
    • Le Floch N, Rivat C, De Wever O, et al: The proinvasive activity of Wnt-2 is mediated through a noncanonical Wnt pathway coupled to GSK-3β and c-Jun/AP-1 signaling. FASEB J 19: 144-146, 2005.
    • (2005) FASEB J , vol.19 , pp. 144-146
    • Le Floch, N.1    Rivat, C.2    De Wever, O.3
  • 44
    • 77949346468 scopus 로고    scopus 로고
    • FOXO1 and TCF7L2 genes involved in metastasis and poor prognosis in clear cell renal cell carcinoma
    • Kojima T, Shimazui T, Horie R, et al: FOXO1 and TCF7L2 genes involved in metastasis and poor prognosis in clear cell renal cell carcinoma. Genes Chromosomes Cancer 49: 379-389, 2010.
    • (2010) Genes Chromosomes Cancer , vol.49 , pp. 379-389
    • Kojima, T.1    Shimazui, T.2    Horie, R.3
  • 45
    • 33747370384 scopus 로고    scopus 로고
    • Multiple roles of FOXO transcription factors in mammalian cells point to multiple roles in cancer
    • Arden KC: Multiple roles of FOXO transcription factors in mammalian cells point to multiple roles in cancer. Exp Gerontol 41: 709-717, 2006.
    • (2006) Exp Gerontol , vol.41 , pp. 709-717
    • Arden, K.C.1
  • 46
    • 77954675751 scopus 로고    scopus 로고
    • Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer
    • Roy S, Srivastava R and Shankar S: Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer. J Mol Signal 5: 10, 2010.
    • (2010) J Mol Signal , vol.5 , pp. 10
    • Roy, S.1    Srivastava, R.2    Shankar, S.3
  • 47
    • 0034956272 scopus 로고    scopus 로고
    • The role of matrix metalloproteinases in tumor angiogenesis and tumor metastasis
    • John A and Tuszynski G: The role of matrix metalloproteinases in tumor angiogenesis and tumor metastasis. Pathol Oncol Res 7: 14-23, 2001.
    • (2001) Pathol Oncol Res , vol.7 , pp. 14-23
    • John, A.1    Tuszynski, G.2


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