Identification of retinal ganglion cell neuroprotection conferred by platelet-derived growth factor through analysis of the mesenchymal stem cell secretome

Brain

Volumn 137, Issue 2, 2014, Pages 503-519

  Johnson, Thomas V ^a,b,c   Dekorver, Nicholas W ^a   Levasseur, Victoria A ^a   Osborne, Andrew ^b   Tassoni, Alessia ^b   Lorber, Barbara ^b   Heller, Janosch P ^b   Villasmil, Rafael ^a   Bull, Natalie D ^b   Martin, Keith R ^b   Tomarev, Stanislav I ^a  

^a NATIONAL EYE INSTITUTE   (United States)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

glaucoma; mesenchymal stem cell; neuroprotection; platelet derived growth factor; retinal ganglion cell

Indexed keywords

ADIPONECTIN; BRAIN DERIVED NEUROTROPHIC FACTOR; FIBROBLAST GROWTH FACTOR 2; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 11; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; MELATONIN; NEUTRALIZING ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR AA; PLATELET DERIVED GROWTH FACTOR AB; SCATTER FACTOR; SOMATOMEDIN C; STEM CELL FACTOR; THROMBOSPONDIN 1; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL SURVIVAL; CELL TRANSPLANTATION; COCULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; EXPLANT; FIBROBLAST; FLOW CYTOMETRY; GLAUCOMA; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; INTRAOCULAR HYPERTENSION; INTRAOCULAR PRESSURE; LASER COAGULATION; MESENCHYMAL STEM CELL; MONONUCLEAR CELL; MOUSE; NERVE FIBER; NEUROPROTECTION; NONHUMAN; OPTIC NERVE; PRIORITY JOURNAL; PROTEIN SECRETION; RAT; RETINA GANGLION CELL; RETINA INNER PLEXIFORM LAYER; SIGNAL TRANSDUCTION; TRABECULAR MESHWORK;

GLAUCOMA; MESENCHYMAL STEM CELL; NEUROPROTECTION; PLATELET DERIVED GROWTH FACTOR; RETINAL GANGLION CELL;

ANIMALS; AXOTOMY; COCULTURE TECHNIQUES; HUMANS; MESENCHYMAL STROMAL CELLS; NEUROPROTECTIVE AGENTS; PLATELET-DERIVED GROWTH FACTOR; RATS; RATS, SPRAGUE-DAWLEY; RATS, TRANSGENIC; RETINAL GANGLION CELLS;

EID: 84893866113     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awt292     Document Type: Article

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