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Volumn 51, Issue 12, 2010, Pages 6394-6400

Intravitreal injections of neurotrophic factors secreting mesenchymal stem cells are neuroprotective in rat eyes following optic nerve transaction

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROGOLD; NEUROTROPHIC FACTOR; PHOSPHATE BUFFERED SALINE;

EID: 79955063380     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.09-4310     Document Type: Article
Times cited : (109)

References (43)
  • 1
    • 9944259509 scopus 로고    scopus 로고
    • Stem cells to replace the optic nerve
    • Quigley HA, Iglesia DS. Stem cells to replace the optic nerve. Eye. 2004;18(11):1085-1088.
    • (2004) Eye , vol.18 , Issue.11 , pp. 1085-1088
    • Quigley, H.A.1    Iglesia, D.S.2
  • 2
  • 3
    • 70350144849 scopus 로고    scopus 로고
    • Transplantation prospects for the inner retina
    • Johnson TV, Bull ND, Martin KR. Transplantation prospects for the inner retina. Eye. 2009;23(10):1980-1984.
    • (2009) Eye , vol.23 , Issue.10 , pp. 1980-1984
    • Johnson, T.V.1    Bull, N.D.2    Martin, K.R.3
  • 4
    • 48549084132 scopus 로고    scopus 로고
    • Molecular and cell-based approaches for neuroprotection in glaucoma
    • Lebrun-Julien F, Di Polo A. Molecular and cell-based approaches for neuroprotection in glaucoma. Optom Vis Sci. 2008;85(6):417-424.
    • (2008) Optom Vis Sci , vol.85 , Issue.6 , pp. 417-424
    • Lebrun-Julien, F.1    Di, P.A.2
  • 6
    • 0035209631 scopus 로고    scopus 로고
    • Optic nerve protection, regeneration, and repair in the 21st century: LVIII Edward Jackson Memorial lecture
    • Miller NR. Optic nerve protection, regeneration, and repair in the 21st century: LVIII Edward Jackson Memorial lecture. Am J Ophthalmol. 2001;132(6):811-818.
    • (2001) Am J Ophthalmol , vol.132 , Issue.6 , pp. 811-818
    • Miller, N.R.1
  • 7
    • 34249885088 scopus 로고    scopus 로고
    • Light at the end of the tunnel? Advances in the understanding and treatment of glaucoma and inherited retinal degeneration
    • Ofri R, Narfstrom K. Light at the end of the tunnel? Advances in the understanding and treatment of glaucoma and inherited retinal degeneration. Vet J. 2007;174(1):10-22.
    • (2007) Vet J , vol.174 , Issue.1 , pp. 10-22
    • Ofri, R.1    Narfstrom, K.2
  • 8
    • 62049083974 scopus 로고    scopus 로고
    • Umbilical cord blood mesenchymal stromal cells are neuroprotective and promote regeneration in a rat optic tract model
    • Zwart I, Hill AJ, Al-Allaf F, et al. Umbilical cord blood mesenchymal stromal cells are neuroprotective and promote regeneration in a rat optic tract model. Exp Neurol. 2009;216(2):439-448.
    • (2009) Exp Neurol , vol.216 , Issue.2 , pp. 439-448
    • Zwart, I.1    Hill, A.J.2    Al-Allaf, F.3
  • 9
    • 38549165911 scopus 로고    scopus 로고
    • Transplantation of cells from eye-like structures differentiated from embryonic stem cells in vitro and in vivo regeneration of retinal ganglion-like cells
    • Aoki H, Hara A, Niwa M, et al. Transplantation of cells from eye-like structures differentiated from embryonic stem cells in vitro and in vivo regeneration of retinal ganglion-like cells. Graefes Arch Clin Exp Ophthalmol. 2008;246(2):255-265.
    • (2008) Graefes Arch Clin Exp Ophthalmol , vol.246 , Issue.2 , pp. 255-265
    • Aoki, H.1    Hara, A.2    Niwa, M.3
  • 10
    • 70349257376 scopus 로고    scopus 로고
    • Transplanted oligodendrocyte precursor cells reduce neurodegeneration in a model of glaucoma
    • Bull ND, Irvine KA, Franklin R, Martin K. Transplanted oligodendrocyte precursor cells reduce neurodegeneration in a model of glaucoma. Invest Ophthalmol Vis Sci. 2009;50:4244-4253.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 4244-4253
    • Bull, N.D.1    Irvine, K.A.2    Franklin, R.3    Martin, K.4
  • 11
    • 49049108522 scopus 로고    scopus 로고
    • Human Müller stem cell (MIO-M1) transplantation in a rat model of glaucoma: Survival, differentiation, and integration
    • Bull ND, Limb GA, Martin KR. Human Müller stem cell (MIO-M1) transplantation in a rat model of glaucoma: survival, differentiation, and integration. Invest Ophthalmol Vis Sci. 2008;49(8): 3449-3456.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , Issue.8 , pp. 3449-3456
    • Bull, N.D.1    Limb, G.A.2    Martin, K.R.3
  • 12
    • 49049120741 scopus 로고    scopus 로고
    • Engrafted chicken neural tube-derived stem cells support the innate propensity for axonal regeneration within the rat optic nerve
    • Charalambous P, Hurst LA, Thanos S. Engrafted chicken neural tube-derived stem cells support the innate propensity for axonal regeneration within the rat optic nerve. Invest Ophthalmol Vis Sci. 2008;49(8):3513-3524.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , Issue.8 , pp. 3513-3524
    • Charalambous, P.1    Hurst, L.A.2    Thanos, S.3
  • 13
    • 0036741335 scopus 로고    scopus 로고
    • Protection of retinal ganglion cells against glaucomatous neuropathy by neurotrophin-producing, genetically modified neural progenitor cells in a rat model
    • Wang N, Zeng M, Ruan Y, et al. Protection of retinal ganglion cells against glaucomatous neuropathy by neurotrophin-producing, genetically modified neural progenitor cells in a rat model. Chin Med J (Engl). 2002;115(9):1394-1400.
    • (2002) Chin Med J (Engl) , vol.115 , Issue.9 , pp. 1394-1400
    • Wang, N.1    Zeng, M.2    Ruan, Y.3
  • 14
    • 71949098755 scopus 로고    scopus 로고
    • Induction of adult human bone marrow mesenchymal stromal cells into functional astrocyte-like cells: Potential for restorative treatment in Parkinson's disease
    • Bahat-Stroomza M, Barhum Y, Levy YS, et al. Induction of adult human bone marrow mesenchymal stromal cells into functional astrocyte-like cells: potential for restorative treatment in Parkinson's disease. J Mol Neurosci. 2009;39(1-2):199-210.
    • (2009) J Mol Neurosci , vol.39 , Issue.1-2 , pp. 199-210
    • Bahat-Stroomza, M.1    Barhum, Y.2    Levy, Y.S.3
  • 15
    • 33646566806 scopus 로고    scopus 로고
    • Human mesenchymal stem cells express neural genes, suggesting a neural predisposition
    • Blondheim NR, Levy YS, Ben-Zur T, et al. Human mesenchymal stem cells express neural genes, suggesting a neural predisposition. Stem Cells Dev. 2006;15(2):141-164.
    • (2006) Stem Cells Dev , vol.15 , Issue.2 , pp. 141-164
    • Blondheim, N.R.1    Levy, Y.S.2    Ben-Zur, T.3
  • 16
    • 33749985102 scopus 로고    scopus 로고
    • Neural differentiation of human mesenchymal stem cells: Evidence for expression of neural markers and eag K channel type
    • Mareschi K, Novara M, Rustichelli D, et al. Neural differentiation of human mesenchymal stem cells: evidence for expression of neural markers and eag K channel types. Exp Hematol. 2006;34(11): 1563-1572.
    • (2006) Exp Hemato , vol.34 , Issue.11 , pp. 1563-1157
    • Mareschi, K.1    Novara, M.2    Rustichelli, D.3
  • 17
    • 16244408979 scopus 로고    scopus 로고
    • Plasticity and therapeutic potential of mesenchymal stem cells in the nervous system
    • Phinney DG, Isakova I. Plasticity and therapeutic potential of mesenchymal stem cells in the nervous system. Curr Pharm Des. 2005;11(10):1255-1265.
    • (2005) Curr Pharm Des , vol.11 , Issue.10 , pp. 1255-1265
    • Phinney, D.G.1    Isakova, I.2
  • 18
    • 15444380614 scopus 로고    scopus 로고
    • Integral therapeutic potential of bone marrow mesenchymal stem cells
    • Kan I, Melamed E, Offen D. Integral therapeutic potential of bone marrow mesenchymal stem cells. Curr Drug Targets. 2005;6(1): 31-41.
    • (2005) Curr Drug Targets , vol.6 , Issue.1 , pp. 31-41
    • Kan, I.1    Melamed, E.2    Offen, D.3
  • 19
    • 34547607603 scopus 로고    scopus 로고
    • Autotransplantation of bone marrow-derived stem cells as a therapy for neurodegenerative diseases
    • Kan I, Melamed E, Offen D. Autotransplantation of bone marrow-derived stem cells as a therapy for neurodegenerative diseases. Handb Exp Pharmacol. 2007(180):219-242.
    • (2007) Handb Exp Pharmacol , vol.180 , pp. 219-242
    • Kan, I.1    Melamed, E.2    Offen, D.3
  • 20
    • 38449109612 scopus 로고    scopus 로고
    • Intrastriatal transplantation of mouse bone marrow-derived stem cells improves motor behavior in a mouse model of Parkinson's disease
    • Offen D, Barhum Y, Levy YS, et al. Intrastriatal transplantation of mouse bone marrow-derived stem cells improves motor behavior in a mouse model of Parkinson's disease. J Neural Transm Suppl. 2007(72):133-143.
    • (2007) J Neural Transm Suppl , vol.72 , pp. 133-143
    • Offen, D.1    Barhum, Y.2    Levy, Y.S.3
  • 21
    • 49349085868 scopus 로고    scopus 로고
    • Human mesenchymal stem cell transplantation extends survival, improves motor performance and decreases neuroinflammation in mouse model of amyotrophic lateral sclerosis
    • Vercelli A, Mereuta OM, Garbossa D, et al. Human mesenchymal stem cell transplantation extends survival, improves motor performance and decreases neuroinflammation in mouse model of amyotrophic lateral sclerosis. Neurobiol Dis. 2008;31(3):395-405.
    • (2008) Neurobiol Dis , vol.31 , Issue.3 , pp. 395-405
    • Vercelli, A.1    Mereuta, O.M.2    Garbossa, D.3
  • 22
    • 50149096420 scopus 로고    scopus 로고
    • Use of bone marrow mesenchymal (stromal) stem cells in experimental ischemic stroke in rats
    • Skvortsova VI, Gubskiy LV, Tairova RT, et al. Use of bone marrow mesenchymal (stromal) stem cells in experimental ischemic stroke in rats. Bull Exp Biol Med. 2008;145(1):122-128.
    • (2008) Bull Exp Biol Med , vol.145 , Issue.1 , pp. 122-128
    • Skvortsova, V.I.1    Gubskiy, L.V.2    Tairova, R.T.3
  • 23
    • 57049089034 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stem cells for the treatment of ischemic stroke
    • Dharmasaroja P. Bone marrow-derived mesenchymal stem cells for the treatment of ischemic stroke. J Clin Neurosci. 2009;16(1): 12-20.
    • (2009) J Clin Neurosci , vol.16 , Issue.1 , pp. 12-20
    • Dharmasaroja, P.1
  • 24
    • 45149103232 scopus 로고    scopus 로고
    • Neuroprotection and immunomodulation with mesenchymal stem cells in chronic experimental autoimmune encephalomyelitis
    • Kassis I, Grigoriadis N, Gowda-Kurkalli B, et al. Neuroprotection and immunomodulation with mesenchymal stem cells in chronic experimental autoimmune encephalomyelitis. Arch Neurol. 2008; 65(6):753-761.
    • (2008) Arch Neurol , vol.65 , Issue.6 , pp. 753-761
    • Kassis, I.1    Grigoriadis, N.2    Gowda-Kurkalli, B.3
  • 25
    • 55749098498 scopus 로고    scopus 로고
    • Stem/progenitor cells from bone marrow decrease neuronal death in global ischemia by modulation of inflammatory/immune responses
    • Ohtaki H, Ylostalo JH, Foraker JE, et al. Stem/progenitor cells from bone marrow decrease neuronal death in global ischemia by modulation of inflammatory/immune responses. Proc Natl Acad Sci U S A. 2008;105(38):14638-14643.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.38 , pp. 14638-14643
    • Ohtaki, H.1    Ylostalo, J.H.2    Foraker, J.E.3
  • 26
    • 34548065507 scopus 로고    scopus 로고
    • Treatment of adult neural progenitor cells prior to transplantation affects graft survival and integration in a neonatal and adult rat model of selective retinal ganglion cell depletion
    • Mellough CB, Cui Q, Harvey AR. Treatment of adult neural progenitor cells prior to transplantation affects graft survival and integration in a neonatal and adult rat model of selective retinal ganglion cell depletion. Restor Neurol Neurosci. 2007;25(2):177-190.
    • (2007) Restor Neurol Neurosci , vol.25 , Issue.2 , pp. 177-190
    • Mellough, C.B.1    Cui, Q.2    Harvey, A.R.3
  • 27
    • 65349155750 scopus 로고    scopus 로고
    • Human umbilical cord bloodderived mesenchymal stem cells do not differentiate into neural cell types or integrate into the retina after intravitreal grafting in neonatal rats
    • Hill AJ, Zwart I, Tam HH, et al. Human umbilical cord bloodderived mesenchymal stem cells do not differentiate into neural cell types or integrate into the retina after intravitreal grafting in neonatal rats. Stem Cells Dev. 2009;18(3):399-409.
    • (2009) Stem Cells Dev , vol.18 , Issue.3 , pp. 399-409
    • Hill, A.J.1    Zwart, I.2    Tam, H.H.3
  • 28
    • 0842308889 scopus 로고    scopus 로고
    • CNTF promotes survival of retinal ganglion cells after induction of ocular hypertension in rats: The possible involvement of STAT3 pathway
    • Ji JZ, Elyaman W, Yip HK, et al. CNTF promotes survival of retinal ganglion cells after induction of ocular hypertension in rats: the possible involvement of STAT3 pathway. Eur J Neurosci. 2004; 19(2):265-272.
    • (2004) Eur J Neurosci , vol.19 , Issue.2 , pp. 265-272
    • Ji, J.Z.1    Elyaman, W.2    Yip, H.K.3
  • 29
    • 34848928410 scopus 로고    scopus 로고
    • Intravitreal injections of GDNFloaded biodegradable microspheres are neuroprotective in a ratmodel of glaucoma
    • Jiang C, Moore MJ, Zhang X, et al. Intravitreal injections of GDNFloaded biodegradable microspheres are neuroprotective in a ratmodel of glaucoma. Mol Vis. 2007;13:1783-1792.
    • (2007) Mol Vis , vol.13 , pp. 1783-1792
    • Jiang, C.1    Moore, M.J.2    Zhang, X.3
  • 30
    • 0141430092 scopus 로고    scopus 로고
    • Gene therapy with brainderived neurotrophic factor as a protection: Retinal ganglion cells in a rat glaucoma model
    • Martin KR, Quigley HA, Zack DJ, et al. Gene therapy with brainderived neurotrophic factor as a protection: retinal ganglion cells in a rat glaucoma model. Invest Ophthalmol Vis Sci. 2003;44(10): 4357-4365.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , Issue.10 , pp. 4357-4365
    • Martin, K.R.1    Quigley, H.A.2    Zack, D.J.3
  • 31
    • 65549157079 scopus 로고    scopus 로고
    • Effect of CNTF on retinal ganglion cell survival in experimental glaucoma
    • Pease ME, Zack DJ, Berlinicke CA, et al. Effect of CNTF on retinal ganglion cell survival in experimental glaucoma. Invest Ophthalmol Vis Sci. 2009;50:2194-2200.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 2194-2200
    • Pease, M.E.1    Zack, D.J.2    Berlinicke, C.A.3
  • 32
    • 27644496187 scopus 로고    scopus 로고
    • Delivery of neurotrophic factors and therapeutic proteins for retinal diseases
    • Thanos C, Emerich D. Delivery of neurotrophic factors and therapeutic proteins for retinal diseases. Expert Opin Biol Ther. 2005; 5(11):1443-1452.
    • (2005) Expert Opin Biol Ther , vol.5 , Issue.11 , pp. 1443-1452
    • Thanos, C.1    Emerich, D.2
  • 33
    • 0037258145 scopus 로고    scopus 로고
    • Delivery of ciliary neurotrophic factor via lentiviral-mediated transfer protects axotomized retinal ganglion cells for an extended period of time
    • van Adel BA, Kostic C, Deglon N, et al. Delivery of ciliary neurotrophic factor via lentiviral-mediated transfer protects axotomized retinal ganglion cells for an extended period of time. Hum Gene Ther. 2003;14(2):103-115.
    • (2003) Hum Gene Ther , vol.14 , Issue.2 , pp. 103-115
    • van Adel, B.A.1    Kostic, C.2    Deglon, N.3
  • 34
    • 33947538421 scopus 로고    scopus 로고
    • Neuroprotection of retinal ganglion cells in DBA/2J mice with GDNF-loaded biodegradable microspheres
    • Ward MS, Khoobehi A, Lavik EB, et al. Neuroprotection of retinal ganglion cells in DBA/2J mice with GDNF-loaded biodegradable microspheres. J Pharm Sci. 2007;96(3):558-568.
    • (2007) J Pharm Sci , vol.96 , Issue.3 , pp. 558-568
    • Ward, M.S.1    Khoobehi, A.2    Lavik, E.B.3
  • 35
    • 67549118438 scopus 로고    scopus 로고
    • Protective effects of neurotrophic factors secreting cells in a 6OHDA rat model of Parkinson disease
    • Sadan O, Bahat-Stromza M, Barhum Y, et al. Protective effects of neurotrophic factors secreting cells in a 6OHDA rat model of Parkinson disease. Stem Cells Dev. 2009;18(8):1179-1190.
    • (2009) Stem Cells Dev , vol.18 , Issue.8 , pp. 1179-1190
    • Sadan, O.1    Bahat-Stromza, M.2    Barhum, Y.3
  • 36
    • 55049132757 scopus 로고    scopus 로고
    • Migration of neurotrophic factors-secreting mesenchymal stem cells toward a quinolinic acid lesion as viewed by magnetic resonance imaging
    • Sadan O, Shemesh N, Barzilay R, et al. Migration of neurotrophic factors-secreting mesenchymal stem cells toward a quinolinic acid lesion as viewed by magnetic resonance imaging. Stem Cells. 2008;26(10):2542-2551.
    • (2008) Stem Cells , vol.26 , Issue.10 , pp. 2542-2551
    • Sadan, O.1    Shemesh, N.2    Barzilay, R.3
  • 37
    • 47249119239 scopus 로고    scopus 로고
    • Regenerative effect of neural-induced human mesenchymal stromal cells in rat models of Parkinson's disease
    • Levy YS, Bahat-Stroomza M, Barzilay R, et al. Regenerative effect of neural-induced human mesenchymal stromal cells in rat models of Parkinson's disease. Cytotherapy. 2008;10(4):340-352.
    • (2008) Cytotherapy , vol.10 , Issue.4 , pp. 340-352
    • Levy, Y.S.1    Bahat-Stroomza, M.2    Barzilay, R.3
  • 38
    • 33646176134 scopus 로고    scopus 로고
    • Effects of bone marrow stromal cell injection in an experimental glaucoma model
    • Yu S, Tanabe T, Dezawa M, et al. Effects of bone marrow stromal cell injection in an experimental glaucoma model. Biochem Biophys Res Commun. 2006;344(4):1071-1079.
    • (2006) Biochem Biophys Res Commun , vol.344 , Issue.4 , pp. 1071-1079
    • Yu, S.1    Tanabe, T.2    Dezawa, M.3
  • 39
    • 62149142133 scopus 로고    scopus 로고
    • Effects of bone-marrow mesenchymal stem cells transplanted into vitreous cavity of rat injured by ischemia/ reperfusion
    • Li N, Li XR, Yuan JQ. Effects of bone-marrow mesenchymal stem cells transplanted into vitreous cavity of rat injured by ischemia/ reperfusion. Graefes Arch Clin Exp Ophthalmol. 2009;247(4): 503-514.
    • (2009) Graefes Arch Clin Exp Ophthalmol , vol.247 , Issue.4 , pp. 503-514
    • Li, N.1    Li, X.R.2    Yuan, J.Q.3
  • 40
    • 41049110191 scopus 로고    scopus 로고
    • Retinal cells integrate into the outer nuclear layer and differentiate into mature photoreceptors after subretinal transplantation into adult mice
    • Bartsch U, Oriyakhel W, Kenna PF, et al. Retinal cells integrate into the outer nuclear layer and differentiate into mature photoreceptors after subretinal transplantation into adult mice. Exp Eye Res. 2008;86(4):691-700.
    • (2008) Exp Eye Res , vol.86 , Issue.4 , pp. 691-700
    • Bartsch, U.1    Oriyakhel, W.2    Kenna, P.F.3
  • 41
    • 33750861299 scopus 로고    scopus 로고
    • Retinal repair by transplantation of photoreceptor precursors
    • MacLaren RE, Pearson RA, MacNeil A, et al. Retinal repair by transplantation of photoreceptor precursors. Nature. 2006; 444(7116):203-207.
    • (2006) Nature , vol.444 , Issue.7116 , pp. 203-207
    • Maclaren, R.E.1    Pearson, R.A.2    Macneil, A.3
  • 42
    • 15244346393 scopus 로고    scopus 로고
    • Photoreceptor differentiation and integration of retinal progenitor cells transplanted into transgenic rats
    • Qiu G, Seiler MJ, Mui C, et al. Photoreceptor differentiation and integration of retinal progenitor cells transplanted into transgenic rats. Exp Eye Res. 2005;80(4):515-525.
    • (2005) Exp Eye Res , vol.80 , Issue.4 , pp. 515-525
    • Qiu, G.1    Seiler, M.J.2    Mui, C.3
  • 43
    • 33947095602 scopus 로고    scopus 로고
    • Transplantation of bone marrow-derived mesenchymal stem cells rescue photoreceptor cells in the dystrophic retina of the rhodopsin knockout mouse
    • Arnhold S, Absenger Y, Klein H, et al. Transplantation of bone marrow-derived mesenchymal stem cells rescue photoreceptor cells in the dystrophic retina of the rhodopsin knockout mouse. Graefes Arch Clin Exp Ophthalmol. 2007;245(3):414-422.
    • (2007) Graefes Arch Clin Exp Ophthalmol , vol.245 , Issue.3 , pp. 414-422
    • Arnhold, S.1    Absenger, Y.2    Klein, H.3


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