Using weighted entropy to rank chemicals in quantitative high-throughput screening experiments

Journal of Biomolecular Screening

Volumn 19, Issue 3, 2014, Pages 344-353

  Shockley, Keith R ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

concentration response; information theory; quantitative high throughput screening; Tox21

Indexed keywords

1,3 DIIMINOBENZ(F)ISOINDOLINE; 4 (1 METHYL 1 PHENYLETHYL)PHENOL; 5BETA ANDROSTANOLONE; 6 HYDROXY 2 NAPHTHYL DISULFIDE; AMINOACRIDINE; ANDROGEN RECEPTOR AGONIST; ANDROSTENEDIONE; CORTICOSTERONE; CROTON OIL; DACTINOMYCIN; DAUNORUBICIN; DEXAMETHASONE; DIGOXIN; DOXORUBICIN; ESTRADIOL; ESTROGEN RECEPTOR AGONIST; FLUOXYMESTERONE; HORMONE RECEPTOR STIMULATING AGENT; MALACHITE GREEN; MEDROXYPROGESTERONE ACETATE; METHYLTESTOSTERONE; OXYMETHOLONE; PREDNISONE; PROGESTERONE; TESTOSTERONE; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; HIGH THROUGHPUT SCREENING; INFORMATION SCIENCE; LIMIT OF DETECTION; MATHEMATICAL MODEL; MATHEMATICAL PHENOMENA; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RECEIVER OPERATING CHARACTERISTIC; SHANNON ENTROPY; STATISTICAL MODEL;

CONCENTRATION RESPONSE; INFORMATION THEORY; QUANTITATIVE HIGH-THROUGHPUT SCREENING; TOX21;

ALGORITHMS; COMPUTER SIMULATION; DRUG EVALUATION, PRECLINICAL; ENTROPY; HIGH-THROUGHPUT SCREENING ASSAYS; MODELS, THEORETICAL; ORPHAN NUCLEAR RECEPTORS; SMALL MOLECULE LIBRARIES;

EID: 84893863908     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057113505325     Document Type: Article

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