-
1
-
-
79952232216
-
Global cancer statistics
-
21296855 10.3322/caac.20107
-
Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D (2011) Global cancer statistics. CA Cancer J Clin 61:69-90
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
2
-
-
33745297408
-
New signals from the invasive front
-
DOI 10.1038/nature04872, PII NATURE04872
-
Christofori G (2006) New signals from the invasive front. Nature 441:444-450 (Pubitemid 44050139)
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 444-450
-
-
Christofori, G.1
-
3
-
-
7944236785
-
Src family kinases, key regulators of signal transduction
-
DOI 10.1038/sj.onc.1208160
-
Parsons SJ, Parsons JT (2004) Src family kinases, key regulators of signal transduction. Oncogene 23:7906-7909 (Pubitemid 39468849)
-
(2004)
Oncogene
, vol.23
, Issue.48 REV. ISSUE 7
, pp. 7906-7909
-
-
Parsons, S.J.1
Parsons, J.T.2
-
4
-
-
2942618768
-
A renaissance for SRC
-
Yeatman TJ (2004) A renaissance for SRC. Nat Rev Cancer 4:470-480 (Pubitemid 38745532)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.6
, pp. 470-480
-
-
Yeatman, T.J.1
-
6
-
-
48749118203
-
Targeting Src in breast cancer
-
1:STN:280:DC%2BD1cvotV2rsw%3D%3D 18487549 10.1093/annonc/mdn291
-
Finn RS (2008) Targeting Src in breast cancer. Ann Oncol 19:1379-1386
-
(2008)
Ann Oncol
, vol.19
, pp. 1379-1386
-
-
Finn, R.S.1
-
7
-
-
75749103348
-
Src signaling in cancer invasion
-
1:CAS:528:DC%2BC3cXhtlSit70%3D 20049846
-
Guarino M (2010) Src signaling in cancer invasion. J Cell Physiol 223:14-26
-
(2010)
J Cell Physiol
, vol.223
, pp. 14-26
-
-
Guarino, M.1
-
8
-
-
7244247062
-
Endothelial barrier disruption by VEGF-mediated Src activity potentiates tumor cell extravasation and metastasis
-
DOI 10.1083/jcb.200408130
-
Weis S, Cui J, Barnes L, Cheresh D (2004) Endothelial barrier disruption by VEGF-mediated Src activity potentiates tumor cell extravasation and metastasis. J Cell Biol 167:223-229 (Pubitemid 39435066)
-
(2004)
Journal of Cell Biology
, vol.167
, Issue.2
, pp. 223-229
-
-
Weis, S.1
Cui, J.2
Barnes, L.3
Cheresh, D.4
-
10
-
-
77955505020
-
Targeted inhibition of SRC kinase signaling attenuates pancreatic tumorigenesis
-
1:CAS:528:DC%2BC3cXpvVOjsbY%3D 3449211 20682659 10.1158/1535-7163.MCT-09- 1212
-
Nagaraj NS, Smith JJ, Revetta F, Washington MK, Merchant NB (2010) Targeted inhibition of SRC kinase signaling attenuates pancreatic tumorigenesis. Mol Cancer Ther 9:2322-2332
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 2322-2332
-
-
Nagaraj, N.S.1
Smith, J.J.2
Revetta, F.3
Washington, M.K.4
Merchant, N.B.5
-
11
-
-
0030795220
-
Trypanocidal activity and redox potential of heterocyclic- and 2-hydroxy-naphthoquinones
-
DOI 10.1016/S0960-894X(97)00354-5, PII S0960894X97003545
-
Goulart MOF, Zani CL, Tonholo J, Freitas LR, deAbreu FC, Oliveira AB, Raslan DS, Starling S, Chiari E (1997) Trypanocidal activity and redox potential of heterocyclic- and 2-hydroxy-naphthoquinones. Bioorg Med Chem Lett 7:2043-2048 (Pubitemid 27338962)
-
(1997)
Bioorganic and Medicinal Chemistry Letters
, vol.7
, Issue.15
, pp. 2043-2048
-
-
Goulart, M.O.F.1
Zani, C.L.2
Tonholo, J.3
Freitas, L.R.4
De Abreu, F.C.5
Oliveira, A.B.6
Raslan, D.S.7
Starling, S.8
Chiari, E.9
-
12
-
-
0038800018
-
Potent antitumor activity of synthetic 1,2-naphthoquinones and 1,4-naphthoquinones
-
DOI 10.1016/S0968-0896(03)00226-8
-
Kongkathip N, Kongkathip B, Siripong P, Sangma C, Luangkamin S, Niyomdecha M, Pattanapa S, Piyaviriyagul S, Kongsaeree P (2003) Potent antitumor activity of synthetic 1,2-naphthoquinones and 1,4-naphthoquinones. Bioorg Med Chem 11:3179-3191 (Pubitemid 36773578)
-
(2003)
Bioorganic and Medicinal Chemistry
, vol.11
, Issue.14
, pp. 3179-3191
-
-
Kongkathip, N.1
Kongkathip, B.2
Siripong, P.3
Sangma, C.4
Luangkamin, S.5
Niyomdecha, M.6
Pattanapa, S.7
Piyaviriyagul, S.8
Kongsaeree, P.9
-
13
-
-
0000277423
-
Naphthofuranone phytoalexins from the grey mangrove, Avicennia Marina
-
1:CAS:528:DyaL28XhtVKntLs%3D 10.1016/0031-9422(85)80018-2
-
Sutton DC, Gillan FT, Susic M (1985) Naphthofuranone phytoalexins from the grey mangrove, Avicennia Marina. Phytochemistry 24:2877-2879
-
(1985)
Phytochemistry
, vol.24
, pp. 2877-2879
-
-
Sutton, D.C.1
Gillan, F.T.2
Susic, M.3
-
14
-
-
69249129139
-
Furo[3′,2′:3,4]naphtho[1,2-d]imidazole derivatives as potential inhibitors of inflammatory factors in sepsis
-
1:CAS:528:DC%2BD1MXhtVOisL%2FL 19699097 10.1016/j.bmc.2009.07.054
-
Tseng CH, Lin CS, Shih PK, Tsao LT, Wang JP, Cheng CM, Tzeng CC, Chen YL (2009) Furo[3′,2′:3,4]naphtho[1,2-d]imidazole derivatives as potential inhibitors of inflammatory factors in sepsis. Bioorg Med Chem 17:6773-6779
-
(2009)
Bioorg Med Chem
, vol.17
, pp. 6773-6779
-
-
Tseng, C.H.1
Lin, C.S.2
Shih, P.K.3
Tsao, L.T.4
Wang, J.P.5
Cheng, C.M.6
Tzeng, C.C.7
Chen, Y.L.8
-
15
-
-
33646410929
-
Distinct roles of nonmuscle myosin II isoforms in the regulation of MDA-MB-231 breast cancer cell spreading and migration
-
1:CAS:528:DC%2BD28XjvF2ktr8%3D 16651425 10.1158/0008-5472.CAN-05-4236
-
Betapudi V, Licate LS, Egelhoff TT (2006) Distinct roles of nonmuscle myosin II isoforms in the regulation of MDA-MB-231 breast cancer cell spreading and migration. Cancer Res 66:4725-4733
-
(2006)
Cancer Res
, vol.66
, pp. 4725-4733
-
-
Betapudi, V.1
Licate, L.S.2
Egelhoff, T.T.3
-
16
-
-
72049088250
-
Naphtho[1,2-b]furan-4,5-dione induces apoptosis and S-phase arrest of MDA-MB-231 cells through JNK and ERK signaling activation
-
1:CAS:528:DC%2BD1MXhsFyktLrL 19747539 10.1016/j.tiv.2009.09.002
-
Lin KL, Su JC, Chien CM, Tseng CH, Chen YL, Chang LS, Lin SR (2010) Naphtho[1,2-b]furan-4,5-dione induces apoptosis and S-phase arrest of MDA-MB-231 cells through JNK and ERK signaling activation. Toxicol In Vitro 24:61-70
-
(2010)
Toxicol in Vitro
, vol.24
, pp. 61-70
-
-
Lin, K.L.1
Su, J.C.2
Chien, C.M.3
Tseng, C.H.4
Chen, Y.L.5
Chang, L.S.6
Lin, S.R.7
-
17
-
-
77954394708
-
Inhibition of epithelial to mesenchymal transition in metastatic breast carcinoma cells by c-Src suppression
-
1:CAS:528:DC%2BC3cXotlCjtbo%3D 20705589 10.1093/abbs/gmq043
-
Liu X, Feng R (2010) Inhibition of epithelial to mesenchymal transition in metastatic breast carcinoma cells by c-Src suppression. Acta Biochim Biophys Sin 42:496-501
-
(2010)
Acta Biochim Biophys Sin
, vol.42
, pp. 496-501
-
-
Liu, X.1
Feng, R.2
-
18
-
-
82455192399
-
PH006, a novel and selective Src kinase inhibitor, suppresses human breast cancer growth and metastasis in vitro and in vivo
-
1:CAS:528:DC%2BC3MXht1Giu7zF 21181437 10.1007/s10549-010-1302-4
-
Ma JG, Huang H, Chen SM, Chen Y, Xin XL, Lin LP, Ding J, Liu H, Meng LH (2011) PH006, a novel and selective Src kinase inhibitor, suppresses human breast cancer growth and metastasis in vitro and in vivo. Breast Cancer Res Treat 130:85-96
-
(2011)
Breast Cancer Res Treat
, vol.130
, pp. 85-96
-
-
Ma, J.G.1
Huang, H.2
Chen, S.M.3
Chen, Y.4
Xin, X.L.5
Lin, L.P.6
Ding, J.7
Liu, H.8
Meng, L.H.9
-
19
-
-
53149139896
-
Phosphorylation of p130Cas initiates Rac activation and membrane ruffling
-
2553404 18793427 10.1186/1471-2121-9-50
-
Sharma A, Mayer BJ (2008) Phosphorylation of p130Cas initiates Rac activation and membrane ruffling. BMC Cell Biol 9:50
-
(2008)
BMC Cell Biol
, vol.9
, pp. 50
-
-
Sharma, A.1
Mayer, B.J.2
-
20
-
-
67650588774
-
Characterisation of fibronectin-mediated FAK signalling pathways in lung cancer cell migration and invasion
-
1:CAS:528:DC%2BD1MXoslOmu7g%3D 2720209 19568240 10.1038/sj.bjc.6605154
-
Meng XN, Jin Y, Yu Y, Bai J, Liu GY, Zhu J, Zhao YZ, Wang Z, Chen F, Lee KY, Fu SB (2009) Characterisation of fibronectin-mediated FAK signalling pathways in lung cancer cell migration and invasion. Br J Cancer 101:327-334
-
(2009)
Br J Cancer
, vol.101
, pp. 327-334
-
-
Meng, X.N.1
Jin, Y.2
Yu, Y.3
Bai, J.4
Liu, G.Y.5
Zhu, J.6
Zhao, Y.Z.7
Wang, Z.8
Chen, F.9
Lee, K.Y.10
Fu, S.B.11
-
21
-
-
0036890288
-
Activation of c-Src is inversely correlated with biological aggressiveness of breast carcinoma
-
DOI 10.1023/A:1020860221099
-
Ito Y, Kawakatsu H, Takeda T, Tani N, Kawaguchi N, Noguchi S, Sakai T, Matsuura N (2002) Activation of c-Src is inversely correlated with biological aggressiveness of breast carcinoma. Breast Cancer Res Treat 76:261-267 (Pubitemid 35335215)
-
(2002)
Breast Cancer Research and Treatment
, vol.76
, Issue.3
, pp. 261-267
-
-
Ito, Y.1
Kawakatsu, H.2
Takeda, T.3
Tani, N.4
Kawaguchi, N.5
Noguchi, S.6
Sakai, T.7
Matsuura, N.8
-
22
-
-
33745257077
-
Inhibition of protein kinase c-Src reduces the incidence of breast cancer metastases and increases survival in mice: Implications for therapy
-
1:CAS:528:DC%2BD28XmsFymsbY%3D 16627750 10.1124/jpet.106.102004
-
Rucci N, Recchia I, Angelucci A, Alamanou M, Del Fattore A, Fortunati D, Susa M, Fabbro D, Bologna M, Teti A (2006) Inhibition of protein kinase c-Src reduces the incidence of breast cancer metastases and increases survival in mice: implications for therapy. J Pharmacol Exp Ther 318:161-172
-
(2006)
J Pharmacol Exp Ther
, vol.318
, pp. 161-172
-
-
Rucci, N.1
Recchia, I.2
Angelucci, A.3
Alamanou, M.4
Del Fattore, A.5
Fortunati, D.6
Susa, M.7
Fabbro, D.8
Bologna, M.9
Teti, A.10
-
23
-
-
0037509990
-
Focal adhesion kinase: The first ten years
-
DOI 10.1242/jcs.00373
-
Parsons JT (2003) Focal adhesion kinase: the first ten years. J Cell Sci 116:1409-1416 (Pubitemid 36527488)
-
(2003)
Journal of Cell Science
, vol.116
, Issue.8
, pp. 1409-1416
-
-
Parsons, J.T.1
-
24
-
-
4644305806
-
Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate (CAS) are sufficient to promote cell migration
-
DOI 10.1074/jbc.M404675200
-
Shin NY, Dise RS, Schneider-Mergener J, Ritchie MD, Kilkenny DM, Hanks SK (2004) Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate (CAS) are sufficient to promote cell migration. J Biol Chem 279:38331-38337 (Pubitemid 39295981)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.37
, pp. 38331-38337
-
-
Shin, N.-Y.1
Dise, R.S.2
Schneider-Mergener, J.3
Ritchie, M.D.4
Kilkenny, D.M.5
Hanks, S.K.6
-
25
-
-
21344443681
-
Crk-associated substrate tyrosine phosphorylation sites are critical for invasion and metastasis of Src-transformed cells
-
DOI 10.1158/1541-7786.MCR-05-0015
-
Brabek J, Constancio SS, Siesser PF, Shin NY, Pozzi A, Hanks SK (2005) Crk-associated substrate tyrosine phosphorylation sites are critical for invasion and metastasis of SRC-transformed cells. Mol Cancer Res 3:307-315 (Pubitemid 40905622)
-
(2005)
Molecular Cancer Research
, vol.3
, Issue.6
, pp. 307-315
-
-
Brabek, J.1
Constancio, S.S.2
Siesser, P.F.3
Shin, N.-Y.4
Pozzi, A.5
Hanks, S.K.6
-
26
-
-
13944282937
-
Identification of Src-specific phosphorylation site on focal adhesion kinase: Dissection of the role of Src SH2 and catalytic functions and their consequences for tumor cell behavior
-
DOI 10.1158/0008-5472.CAN-04-1949
-
Brunton VG, Avizienyte E, Fincham VJ, Serrels B, Metcalf CA 3rd, Sawyer TK, Frame MC (2005) Identification of Src-specific phosphorylation site on focal adhesion kinase: dissection of the role of Src SH2 and catalytic functions and their consequences for tumor cell behavior. Cancer Res 65:1335-1342 (Pubitemid 40270160)
-
(2005)
Cancer Research
, vol.65
, Issue.4
, pp. 1335-1342
-
-
Brunton, V.G.1
Avizienyte, E.2
Fincham, V.J.3
Serrels, B.4
Metcalf III, C.A.5
Sawyer, T.K.6
Frame, M.C.7
-
27
-
-
27144545759
-
Specific induction of pp125 focal adhesion kinase in human breast cancer
-
DOI 10.1038/sj.bjc.6602744, PII 6602744
-
Watermann DO, Gabriel B, Jager M, Orlowska-Volk M, Hasenburg A, zur Hausen A, Gitsch G, Stickeler E (2005) Specific induction of pp125 focal adhesion kinase in human breast cancer. Br J Cancer 93:694-698 (Pubitemid 41486461)
-
(2005)
British Journal of Cancer
, vol.93
, Issue.6
, pp. 694-698
-
-
Watermann, D.O.1
Gabriel, B.2
Jager, M.3
Orlowska-Volk, M.4
Hasenburg, A.5
Zur Hausen, A.6
Gitsch, G.7
Stickeler, E.8
-
28
-
-
33646557326
-
P130Cas: A versatile scaffold in signaling networks
-
DOI 10.1016/j.tcb.2006.03.003, PII S0962892406000833
-
Defilippi P, Di Stefano P, Cabodi S (2006) p130Cas: a versatile scaffold in signaling networks. Trends Cell Biol 16:257-263 (Pubitemid 43728873)
-
(2006)
Trends in Cell Biology
, vol.16
, Issue.5
, pp. 257-263
-
-
Defilippi, P.1
Di Stefano, P.2
Cabodi, S.3
-
29
-
-
49849096075
-
SKI-606 (bosutinib), a novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells
-
1:CAS:528:DC%2BD1cXlvFamsrw%3D 2794837 18483306 10.1158/1535-7163.MCT-08- 0126
-
Vultur A, Buettner R, Kowolik C, Liang W, Smith D, Boschelli F, Jove R (2008) SKI-606 (bosutinib), a novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells. Mol Cancer Ther 7:1185-1194
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 1185-1194
-
-
Vultur, A.1
Buettner, R.2
Kowolik, C.3
Liang, W.4
Smith, D.5
Boschelli, F.6
Jove, R.7
-
30
-
-
79960318305
-
Denbinobin suppresses breast cancer metastasis through the inhibition of Src-mediated signaling pathways
-
1:CAS:528:DC%2BC3MXptVWrsbs%3D 21062671 10.1016/j.jnutbio.2010.06.004
-
Chen PH, Peng CY, Pai HC, Teng CM, Chen CC, Yang CR (2011) Denbinobin suppresses breast cancer metastasis through the inhibition of Src-mediated signaling pathways. J Nutr Biochem 22:732-740
-
(2011)
J Nutr Biochem
, vol.22
, pp. 732-740
-
-
Chen, P.H.1
Peng, C.Y.2
Pai, H.C.3
Teng, C.M.4
Chen, C.C.5
Yang, C.R.6
-
31
-
-
21744435478
-
The role of focal-adhesion kinase in cancer - A new therapeutic opportunity
-
DOI 10.1038/nrc1647
-
McLean GW, Carragher NO, Avizienyte E, Evans J, Brunton VG, Frame MC (2005) The role of focal-adhesion kinase in cancer - a new therapeutic opportunity. Nat Rev Cancer 5:505-515 (Pubitemid 40942827)
-
(2005)
Nature Reviews Cancer
, vol.5
, Issue.7
, pp. 505-515
-
-
McLean, G.W.1
Carragher, N.O.2
Avizienyte, E.3
Evans, J.4
Brunton, V.G.5
Frame, M.C.6
-
32
-
-
27144547509
-
Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells
-
DOI 10.1158/0008-5472.CAN-05-1731
-
Nam S, Kim D, Cheng JQ, Zhang S, Lee JH, Buettner R, Mirosevich J, Lee FY, Jove R (2005) Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells. Cancer Res 65:9185-9189 (Pubitemid 41507982)
-
(2005)
Cancer Research
, vol.65
, Issue.20
, pp. 9185-9189
-
-
Nam, S.1
Kim, D.2
Cheng, J.Q.3
Zhang, S.4
Lee, J.-H.5
Buettner, R.6
Mirosevich, J.7
Lee, F.Y.8
Jove, R.9
-
33
-
-
0035475321
-
Paxillin: A focal adhesion-associated adaptor protein
-
DOI 10.1038/sj.onc.1204786
-
Schaller MD (2001) Paxillin: a focal adhesion-associated adaptor protein. Oncogene 20:6459-6472 (Pubitemid 32977851)
-
(2001)
Oncogene
, vol.20
, Issue.44 REV. ISSUE 5
, pp. 6459-6472
-
-
Schaller, M.D.1
-
34
-
-
62149084526
-
Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion
-
2651180 19138410 10.1186/1471-2407-9-12
-
Sachdev S, Bu Y, Gelman IH (2009) Paxillin-Y118 phosphorylation contributes to the control of Src-induced anchorage-independent growth by FAK and adhesion. BMC Cancer 9:12
-
(2009)
BMC Cancer
, vol.9
, pp. 12
-
-
Sachdev, S.1
Bu, Y.2
Gelman, I.H.3
-
35
-
-
33646576169
-
Matrix metalloproteinases and tumor metastasis
-
DOI 10.1007/s10555-006-7886-9, Metalloproteinases and Cancer
-
Deryugina EI, Quigley JP (2006) Matrix metalloproteinases and tumor metastasis. Cancer Metastasis Rev 25:9-34 (Pubitemid 43723979)
-
(2006)
Cancer and Metastasis Reviews
, vol.25
, Issue.1
, pp. 9-34
-
-
Deryugina, E.I.1
Quigley, J.P.2
-
36
-
-
56449100212
-
Inhibition of Src family kinases with dasatinib blocks migration and invasion of human melanoma cells
-
1:CAS:528:DC%2BD1cXhtlOmtLzJ 2768340 19010823 10.1158/1541-7786.MCR-08- 0169
-
Buettner R, Mesa T, Vultur A, Lee F, Jove R (2008) Inhibition of Src family kinases with dasatinib blocks migration and invasion of human melanoma cells. Mol Cancer Res 6:1766-1774
-
(2008)
Mol Cancer Res
, vol.6
, pp. 1766-1774
-
-
Buettner, R.1
Mesa, T.2
Vultur, A.3
Lee, F.4
Jove, R.5
-
37
-
-
82655162059
-
Nitidine chloride inhibits breast cancer cells migration and invasion by suppressing c-Src/FAK associated signaling pathway
-
1:CAS:528:DC%2BC3MXhsVKhsrzM 21959111 10.1016/j.canlet.2011.09.001
-
Pan X, Han H, Wang L, Yang L, Li R, Li Z, Liu J, Zhao Q, Qian M, Liu M, Du B (2011) Nitidine chloride inhibits breast cancer cells migration and invasion by suppressing c-Src/FAK associated signaling pathway. Cancer Lett 313:181-191
-
(2011)
Cancer Lett
, vol.313
, pp. 181-191
-
-
Pan, X.1
Han, H.2
Wang, L.3
Yang, L.4
Li, R.5
Li, Z.6
Liu, J.7
Zhao, Q.8
Qian, M.9
Liu, M.10
Du, B.11
|