메뉴 건너뛰기




Volumn 75, Issue 5, 2014, Pages 386-397

A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation

(82)  Bramon, Elvira a,b,ai   Pirinen, Matti c   Strange, Amy c   Lin, Kuang b   Freeman, Colin c   Bellenguez, Céline c   Su, Zhan c   Band, Gavin c   Pearson, Richard c   Jankowski, Janusz al,am,an   Langford, Cordelia d,ak   Deloukas, Panos d,ak   Hunt, Sarah d   Gray, Emma d,ak   Dronov, Serge d,ak   Potter, Simon C d,ak   Tashakkori Ghanbaria, Avazeh d,ak   Viswanathan, Ananth C au   Bumpstead, Suzannah J d,ak   Arranz, Maria J b,e   more..


Author keywords

Bipolar disorder; genome wide association; meta analysis; polygenic score analysis; psychosis; schizophrenia

Indexed keywords

ALLELE; ARTICLE; BIPOLAR DISORDER; CONTROLLED STUDY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; PHENOTYPE; POPULATION STRUCTURE; PRIORITY JOURNAL; PSYCHOSIS; SCHIZOAFFECTIVE PSYCHOSIS; SCHIZOPHRENIA; SCORING SYSTEM; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 84893814574     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2013.03.033     Document Type: Article
Times cited : (43)

References (115)
  • 1
    • 0034730786 scopus 로고    scopus 로고
    • Strauss (1969) revisited: A psychosis continuum in the general population?
    • J. van Os, M. Hanssen, R.V. Bijl, and A. Ravelli Strauss (1969) revisited: A psychosis continuum in the general population? Schizophr Res 45 2000 11 20
    • (2000) Schizophr Res , vol.45 , pp. 11-20
    • Van Os, J.1    Hanssen, M.2    Bijl, R.V.3    Ravelli, A.4
  • 2
    • 0034939252 scopus 로고    scopus 로고
    • Prevalence of psychotic disorder and community level of psychotic symptoms: An urban-rural comparison
    • J. van Os, M. Hanssen, R.V. Bijl, and W. Vollebergh Prevalence of psychotic disorder and community level of psychotic symptoms: An urban-rural comparison Arch Gen Psychiatry 58 2001 663 668
    • (2001) Arch Gen Psychiatry , vol.58 , pp. 663-668
    • Van Os, J.1    Hanssen, M.2    Bijl, R.V.3    Vollebergh, W.4
  • 3
    • 0026436979 scopus 로고
    • Schizophrenia - Manifestations, incidence and course in different cultures - A World Health Organization ten-country study
    • A. Jablensky, N. Sartorius, G. Ernberg, M. Anker, A. Korten, and J.E. Cooper et al. Schizophrenia - manifestations, incidence and course in different cultures - a World Health Organization ten-country study Psychological Med 20 1992 1 97
    • (1992) Psychological Med , vol.20 , pp. 1-97
    • Jablensky, A.1    Sartorius, N.2    Ernberg, G.3    Anker, M.4    Korten, A.5    Cooper, J.E.6
  • 6
    • 70349137111 scopus 로고    scopus 로고
    • How common are psychotic and bipolar disorders? A 50-year follow-up of the Lundby population
    • M. Bogren, C. Mattisson, P.E. Isberg, and P. Nettelbladt How common are psychotic and bipolar disorders? A 50-year follow-up of the Lundby population Nord J Psychiatry 63 2009 336 346
    • (2009) Nord J Psychiatry , vol.63 , pp. 336-346
    • Bogren, M.1    Mattisson, C.2    Isberg, P.E.3    Nettelbladt, P.4
  • 7
    • 84893723793 scopus 로고    scopus 로고
    • The World Health Report 2001 - Mental health, new understanding, new hope
    • 117-117
    • WHO The World Health Report 2001 - Mental health, new understanding, new hope Eur J Psychiatry 16 2002 117-117
    • (2002) Eur J Psychiatry , vol.16
    • Who1
  • 8
    • 84863980709 scopus 로고    scopus 로고
    • Genetic architectures of psychiatric disorders: The emerging picture and its implications
    • P.F. Sullivan, M.J. Daly, and M. O'Donovan Genetic architectures of psychiatric disorders: the emerging picture and its implications Nat Rev Genet 13 2012 537 551
    • (2012) Nat Rev Genet , vol.13 , pp. 537-551
    • Sullivan, P.F.1    Daly, M.J.2    O'Donovan, M.3
  • 10
    • 70449732249 scopus 로고    scopus 로고
    • Rare structural variants in schizophrenia: One disorder, multiple mutations; One mutation, multiple disorders
    • J. Sebat, D.L. Levy, and S.E. McCarthy Rare structural variants in schizophrenia: One disorder, multiple mutations; one mutation, multiple disorders Trends Genet 25 2009 528 535
    • (2009) Trends Genet , vol.25 , pp. 528-535
    • Sebat, J.1    Levy, D.L.2    McCarthy, S.E.3
  • 13
    • 80355135154 scopus 로고    scopus 로고
    • Identification of new schizophrenia susceptibility loci in an ethnically homogeneous, family-based, Arab-Israeli sample
    • A. Alkelai, S. Lupoli, L. Greenbaum, I. Giegling, Y. Kohn, and K. Sarner-Kanyas et al. Identification of new schizophrenia susceptibility loci in an ethnically homogeneous, family-based, Arab-Israeli sample FASEB J 25 2011 4011 4023
    • (2011) FASEB J , vol.25 , pp. 4011-4023
    • Alkelai, A.1    Lupoli, S.2    Greenbaum, L.3    Giegling, I.4    Kohn, Y.5    Sarner-Kanyas, K.6
  • 14
    • 77955426959 scopus 로고    scopus 로고
    • Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort
    • L. Athanasiu, M. Mattingsdal, A.K. Kähler, A. Brown, O. Gustafsson, and I. Agartz et al. Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort J Psychiatr Research 44 2010 748 753
    • (2010) J Psychiatr Research , vol.44 , pp. 748-753
    • Athanasiu, L.1    Mattingsdal, M.2    Kähler, A.K.3    Brown, A.4    Gustafsson, O.5    Agartz, I.6
  • 15
    • 77954510735 scopus 로고    scopus 로고
    • The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia
    • E.K. Green, D. Grozeva, I. Jones, L. Jones, G. Kirov, and S. Caesar et al. The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia Mol Psychiatry 15 2010 1016 1022
    • (2010) Mol Psychiatry , vol.15 , pp. 1016-1022
    • Green, E.K.1    Grozeva, D.2    Jones, I.3    Jones, L.4    Kirov, G.5    Caesar, S.6
  • 17
    • 61449229353 scopus 로고    scopus 로고
    • A genome-wide investigation of SNPs and CNVs in schizophrenia
    • A.C. Need, D. Ge, M.E. Weale, J. Maia, S. Feng, and E.L. Heinzen et al. A genome-wide investigation of SNPs and CNVs in schizophrenia PLoS Genet 5 2009 e1000373
    • (2009) PLoS Genet , vol.5 , pp. 1000373
    • Need, A.C.1    Ge, D.2    Weale, M.E.3    Maia, J.4    Feng, S.5    Heinzen, E.L.6
  • 18
    • 50449100461 scopus 로고    scopus 로고
    • Identification of loci associated with schizophrenia by genome-wide association and follow-up
    • M.C. O'Donovan, N. Craddock, N. Norton, H. Williams, T. Peirce, and V. Moskvina et al. Identification of loci associated with schizophrenia by genome-wide association and follow-up Nat Genet 40 2008 1053 1055
    • (2008) Nat Genet , vol.40 , pp. 1053-1055
    • O'Donovan, M.C.1    Craddock, N.2    Norton, N.3    Williams, H.4    Peirce, T.5    Moskvina, V.6
  • 19
    • 58049218976 scopus 로고    scopus 로고
    • Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroblast growth factor receptor 2
    • M.C. O'Donovan, N. Norton, H. Williams, T. Peirce, V. Moskvina, and I. Nikolov et al. Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroblast growth factor receptor 2 Mol Psychiatry 14 2009 30 36
    • (2009) Mol Psychiatry , vol.14 , pp. 30-36
    • O'Donovan, M.C.1    Norton, N.2    Williams, H.3    Peirce, T.4    Moskvina, V.5    Nikolov, I.6
  • 20
    • 0035117713 scopus 로고    scopus 로고
    • Schizophrenia-like psychosis following traumatic brain injury: A chart-based descriptive and case-control study
    • P. Sachdev, J.S. Smith, and S. Cathcart Schizophrenia-like psychosis following traumatic brain injury: A chart-based descriptive and case-control study Psychol Med 31 2001 231 239
    • (2001) Psychol Med , vol.31 , pp. 231-239
    • Sachdev, P.1    Smith, J.S.2    Cathcart, S.3
  • 21
    • 82255175590 scopus 로고    scopus 로고
    • Common variants on 8p12 and 1q24.2 confer risk of schizophrenia
    • Y. Shi, Z. Li, Q. Xu, T. Wang, T. Li, and J. Shen et al. Common variants on 8p12 and 1q24.2 confer risk of schizophrenia Nat Genet 43 2011 1224 1227
    • (2011) Nat Genet , vol.43 , pp. 1224-1227
    • Shi, Y.1    Li, Z.2    Xu, Q.3    Wang, T.4    Li, T.5    Shen, J.6
  • 22
    • 40149105889 scopus 로고    scopus 로고
    • Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women
    • S. Shifman, M. Johannesson, M. Bronstein, S.X. Chen, D.A. Collier, and N.J. Craddock et al. Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women PLoS Genet 4 2008 e28
    • (2008) PLoS Genet , vol.4 , pp. 28
    • Shifman, S.1    Johannesson, M.2    Bronstein, M.3    Chen, S.X.4    Collier, D.A.5    Craddock, N.J.6
  • 23
    • 68449096727 scopus 로고    scopus 로고
    • Common variants on chromosome 6p22.1 are associated with schizophrenia
    • J. Shi, D.F. Levinson, J. Duan, A.R. Sanders, Y. Zheng, and I. Pe'er et al. Common variants on chromosome 6p22.1 are associated with schizophrenia Nature 460 2009 753 757
    • (2009) Nature , vol.460 , pp. 753-757
    • Shi, J.1    Levinson, D.F.2    Duan, J.3    Sanders, A.R.4    Zheng, Y.5    Pe'Er, I.6
  • 26
    • 68449086236 scopus 로고    scopus 로고
    • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
    • S.M. Purcell, N.R. Wray, J.L. Stone, P.M. Visscher, M.C. O'Donovan, and P.F. Sullivan et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder Nature 460 2009 748 752
    • (2009) Nature , vol.460 , pp. 748-752
    • Purcell, S.M.1    Wray, N.R.2    Stone, J.L.3    Visscher, P.M.4    O'Donovan, M.C.5    Sullivan, P.F.6
  • 27
    • 84866616686 scopus 로고    scopus 로고
    • Schizophrenia Genomics Consortium Wellcome Trust Case-Control Consortium 2 I Genome-wide association study implicates HLA-C*01:02 as a risk factor at the major histocompatibility complex locus in schizophrenia
    • Irish Schizophrenia Genomics Consortium, Wellcome Trust Case-Control Consortium 2 Genome-wide association study implicates HLA-C*01:02 as a risk factor at the major histocompatibility complex locus in schizophrenia Biol Psychiatry 72 2012 620 628
    • (2012) Biol Psychiatry , vol.72 , pp. 620-628
  • 28
    • 80053385384 scopus 로고    scopus 로고
    • Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4
    • P. Sklar, S. Ripke, L.J. Scott, O.A. Andreassen, S. Cichon, and N. Craddock et al. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4 Nat Genet 43 2011 977 983
    • (2011) Nat Genet , vol.43 , pp. 977-983
    • Sklar, P.1    Ripke, S.2    Scott, L.J.3    Andreassen, O.A.4    Cichon, S.5    Craddock, N.6
  • 29
    • 84873058959 scopus 로고    scopus 로고
    • Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder
    • D.T. Chen, X. Jiang, N. Akula, Y.Y. Shugart, J.R. Wendland, and C.J.M. Steele et al. Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder Mol Psychiatry 18 2011 195 205
    • (2011) Mol Psychiatry , vol.18 , pp. 195-205
    • Chen, D.T.1    Jiang, X.2    Akula, N.3    Shugart, Y.Y.4    Wendland, J.R.5    Steele, C.J.M.6
  • 30
    • 79952485391 scopus 로고    scopus 로고
    • Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder
    • S. Cichon, T.W. Muhleisen, F.A. Degenhardt, M. Mattheisen, X. Miro, and J. Strohmaier et al. Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder Am J Hum Genet 88 2011 372 381
    • (2011) Am J Hum Genet , vol.88 , pp. 372-381
    • Cichon, S.1    Muhleisen, T.W.2    Degenhardt, F.A.3    Mattheisen, M.4    Miro, X.5    Strohmaier, J.6
  • 31
    • 75649122572 scopus 로고    scopus 로고
    • Strong genetic evidence for a selective influence of GABA(A) receptors on a component of the bipolar disorder phenotype
    • Craddock N, Jones L, Jones IR, Kirov G, Green EK, Grozeva D, et al. (2008): Strong genetic evidence for a selective influence of GABA(A) receptors on a component of the bipolar disorder phenotype. Mol Psychiatry 15:146-153
    • (2008) Mol Psychiatry , vol.15 , pp. 146-153
    • Craddock, N.1    Jones, L.2    Jones, I.R.3    Kirov, G.4    Green, E.K.5    Grozeva, D.6
  • 32
    • 77956262527 scopus 로고    scopus 로고
    • A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample
    • S. Djurovic, O. Gustafsson, M. Mattingsdal, L. Athanasiu, T. Bjella, and M. Tesli et al. A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample J Affect Disord 126 2010 312 316
    • (2010) J Affect Disord , vol.126 , pp. 312-316
    • Djurovic, S.1    Gustafsson, O.2    Mattingsdal, M.3    Athanasiu, L.4    Bjella, T.5    Tesli, M.6
  • 33
    • 50449089356 scopus 로고    scopus 로고
    • Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder
    • M.A. Ferreira, M.C. O'Donovan, Y.A. Meng, I.R. Jones, D.M. Ruderfer, and L. Jones et al. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder Nat Genet 40 2008 1056 1058
    • (2008) Nat Genet , vol.40 , pp. 1056-1058
    • Ferreira, M.A.1    O'Donovan, M.C.2    Meng, Y.A.3    Jones, I.R.4    Ruderfer, D.M.5    Jones, L.6
  • 34
    • 78751547278 scopus 로고    scopus 로고
    • Propensity score-based nonparametric test revealing genetic variants underlying bipolar disorder
    • Y. Jiang, and H. Zhang Propensity score-based nonparametric test revealing genetic variants underlying bipolar disorder Genet Epidemiol 35 2011 125 132
    • (2011) Genet Epidemiol , vol.35 , pp. 125-132
    • Jiang, Y.1    Zhang, H.2
  • 35
    • 83755174462 scopus 로고    scopus 로고
    • Genome-wide association study in bipolar patients stratified by co-morbidity
    • B. Kerner, C.G. Lambert, and B.O. Muthén Genome-wide association study in bipolar patients stratified by co-morbidity PLoS One 6 2011 e28477
    • (2011) PLoS One , vol.6 , pp. 28477
    • Kerner, B.1    Lambert, C.G.2    Muthén, B.O.3
  • 36
    • 79955473843 scopus 로고    scopus 로고
    • Genome-wide association study of bipolar i disorder in the Han Chinese population
    • M.T.M. Lee, C.H. Chen, C.S. Lee, C.C. Chen, M.Y. Chong, and W.C. Ouyang et al. Genome-wide association study of bipolar I disorder in the Han Chinese population Mol Psychiatry 16 2011 548 556
    • (2011) Mol Psychiatry , vol.16 , pp. 548-556
    • Lee, M.T.M.1    Chen, C.H.2    Lee, C.S.3    Chen, C.C.4    Chong, M.Y.5    Ouyang, W.C.6
  • 37
    • 78650510203 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder
    • Y. Liu, D.H. Blackwood, S. Caesar, E.J. de Geus, A. Farmer, and M.A. Ferreira et al. Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder Mol Psychiatry 16 2011 2 4
    • (2011) Mol Psychiatry , vol.16 , pp. 2-4
    • Liu, Y.1    Blackwood, D.H.2    Caesar, S.3    De Geus, E.J.4    Farmer, A.5    Ferreira, M.A.6
  • 38
    • 66149092770 scopus 로고    scopus 로고
    • Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry
    • L.J. Scott, P. Muglia, X.Q. Kong, W. Guan, M. Flickinger, and R. Upmanyu et al. Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry Proc Natl Acad Sci U S A 106 2009 7501 7506
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 7501-7506
    • Scott, L.J.1    Muglia, P.2    Kong, X.Q.3    Guan, W.4    Flickinger, M.5    Upmanyu, R.6
  • 40
    • 67651158803 scopus 로고    scopus 로고
    • Genome-wide association study of bipolar disorder in European American and African American individuals
    • E.N. Smith, C.S. Bloss, J.A. Badner, T. Barrett, P.L. Belmonte, and W. Berrettini et al. Genome-wide association study of bipolar disorder in European American and African American individuals Mol Psychiatry 14 2009 755 763
    • (2009) Mol Psychiatry , vol.14 , pp. 755-763
    • Smith, E.N.1    Bloss, C.S.2    Badner, J.A.3    Barrett, T.4    Belmonte, P.L.5    Berrettini, W.6
  • 41
    • 79959813723 scopus 로고    scopus 로고
    • Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes
    • E.N. Smith, D.L. Koller, C. Panganiban, S. Szelinger, P. Zhang, and J.A. Badner et al. Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes PLoS Genet 7 2011 e1002134
    • (2011) PLoS Genet , vol.7 , pp. 1002134
    • Smith, E.N.1    Koller, D.L.2    Panganiban, C.3    Szelinger, S.4    Zhang, P.5    Badner, J.A.6
  • 42
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: A toolset for whole-genome association and population-based linkage analysis
    • S. Purcell, B. Neale, K. Todd-Brown, L. Thomas, M. Ferreira, and D. Bender et al. PLINK: A toolset for whole-genome association and population-based linkage analysis Am J Hum Genet 81 2007 559 575
    • (2007) Am J Hum Genet , vol.81 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3    Thomas, L.4    Ferreira, M.5    Bender, D.6
  • 44
    • 79951481957 scopus 로고    scopus 로고
    • Initial impact of the sequencing of the human genome
    • E.S. Lander Initial impact of the sequencing of the human genome Nature 470 2011 187 197
    • (2011) Nature , vol.470 , pp. 187-197
    • Lander, E.S.1
  • 46
    • 77955359525 scopus 로고    scopus 로고
    • Genome-wide association study of major recurrent depression in the U.K population
    • C.M. Lewis, M.Y. Ng, A.W. Butler, S. Cohen-Woods, R. Uher, and K. Pirlo et al. Genome-wide association study of major recurrent depression in the U.K. population Am J Psychiatry 167 2010 949 957
    • (2010) Am J Psychiatry , vol.167 , pp. 949-957
    • Lewis, C.M.1    Ng, M.Y.2    Butler, A.W.3    Cohen-Woods, S.4    Uher, R.5    Pirlo, K.6
  • 47
    • 77952927126 scopus 로고    scopus 로고
    • Systematic reviews of categorical versus continuum models in psychosis: Evidence for discontinuous subpopulations underlying a psychometric continuum. Implications for DSM-V, DSM-VI, and DSM-VII
    • R.J. Linscott, and J. van Os Systematic reviews of categorical versus continuum models in psychosis: Evidence for discontinuous subpopulations underlying a psychometric continuum. Implications for DSM-V, DSM-VI, and DSM-VII Annu Rev Clin Psychol 6 2010 391 419
    • (2010) Annu Rev Clin Psychol , vol.6 , pp. 391-419
    • Linscott, R.J.1    Van Os, J.2
  • 48
    • 50949102049 scopus 로고    scopus 로고
    • Meta-analysis, database, and meta-regression of 98 structural imaging studies in bipolar disorder
    • M.J. Kempton, J.R. Geddes, U. Ettinger, S.C. Williams, and P.M. Grasby Meta-analysis, database, and meta-regression of 98 structural imaging studies in bipolar disorder Arch Gen Psychiatry 65 2008 1017 1032
    • (2008) Arch Gen Psychiatry , vol.65 , pp. 1017-1032
    • Kempton, M.J.1    Geddes, J.R.2    Ettinger, U.3    Williams, S.C.4    Grasby, P.M.5
  • 49
    • 0002616202 scopus 로고    scopus 로고
    • The common genetic liability between schizophrenia and bipolar disorder: A review
    • E. Bramon, and P. Sham The common genetic liability between schizophrenia and bipolar disorder: A review Curr Psychiatry Rep 3 2001 332 337
    • (2001) Curr Psychiatry Rep , vol.3 , pp. 332-337
    • Bramon, E.1    Sham, P.2
  • 50
    • 54249161209 scopus 로고    scopus 로고
    • The shared genetic architecture which underlies schizophrenia and bipolar disorder
    • C. McDonald, K. Schulze, R. Murray, P. Wright, Taylor & Francis London
    • E. Bramon, and P. Sham The shared genetic architecture which underlies schizophrenia and bipolar disorder C. McDonald, K. Schulze, R. Murray, P. Wright, Schizophrenia, Challenging the Orthodox 2004 Taylor & Francis London 173 181
    • (2004) Schizophrenia, Challenging the Orthodox , pp. 173-181
    • Bramon, E.1    Sham, P.2
  • 51
    • 58049194158 scopus 로고    scopus 로고
    • A framework for interpreting genome-wide association studies of psychiatric disorders
    • P. Sullivan, S. Cichon, N. Craddock, M. Daly, S.V. Faraone, and P.V. Gejman et al. A framework for interpreting genome-wide association studies of psychiatric disorders Mol Psychiatry 14 2009 10 17
    • (2009) Mol Psychiatry , vol.14 , pp. 10-17
    • Sullivan, P.1    Cichon, S.2    Craddock, N.3    Daly, M.4    Faraone, S.V.5    Gejman, P.V.6
  • 52
    • 78049303903 scopus 로고    scopus 로고
    • Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: A genome-wide analysis
    • N.M. Williams, I. Zaharieva, A. Martin, K. Langley, K. Mantripragada, and R. Fossdal et al. Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: A genome-wide analysis Lancet 376 2010 1401 1408
    • (2010) Lancet , vol.376 , pp. 1401-1408
    • Williams, N.M.1    Zaharieva, I.2    Martin, A.3    Langley, K.4    Mantripragada, K.5    Fossdal, R.6
  • 54
    • 77957960817 scopus 로고    scopus 로고
    • Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression
    • J. Huang, R.H. Perlis, P.H. Lee, A.J. Rush, M. Fava, and G.S. Sachs et al. Cross-disorder genomewide analysis of schizophrenia, bipolar disorder, and depression Am J Psychiatry 167 2010 1254 1263
    • (2010) Am J Psychiatry , vol.167 , pp. 1254-1263
    • Huang, J.1    Perlis, R.H.2    Lee, P.H.3    Rush, A.J.4    Fava, M.5    Sachs, G.S.6
  • 55
    • 78650565096 scopus 로고    scopus 로고
    • Most genome-wide significant susceptibility loci for schizophrenia and bipolar disorder reported to date cross-traditional diagnostic boundaries
    • H.J. Williams, N. Craddock, G. Russo, M.L. Hamshere, V. Moskvina, and S. Dwyer et al. Most genome-wide significant susceptibility loci for schizophrenia and bipolar disorder reported to date cross-traditional diagnostic boundaries Hum Mol Genet 20 2011 387 391
    • (2011) Hum Mol Genet , vol.20 , pp. 387-391
    • Williams, H.J.1    Craddock, N.2    Russo, G.3    Hamshere, M.L.4    Moskvina, V.5    Dwyer, S.6
  • 56
    • 77957914609 scopus 로고    scopus 로고
    • The Psychiatric GWAS Consortium: Big science comes to psychiatry
    • P.F. Sullivan The Psychiatric GWAS Consortium: Big science comes to psychiatry Neuron 68 2010 182 186
    • (2010) Neuron , vol.68 , pp. 182-186
    • Sullivan, P.F.1
  • 57
    • 84855360075 scopus 로고    scopus 로고
    • Genome-wide association study of major depressive disorder: New results, meta-analysis, and lessons learned
    • N.R. Wray, M.L. Pergadia, D.H.R. Blackwood, BWJH Penninx, S.D. Gordon, and D.R. Nyholt et al. Genome-wide association study of major depressive disorder: New results, meta-analysis, and lessons learned Mol Psychiatry 17 2012 36 48
    • (2012) Mol Psychiatry , vol.17 , pp. 36-48
    • Wray, N.R.1    Pergadia, M.L.2    Blackwood, D.H.R.3    Penninx, B.4    Gordon, S.D.5    Nyholt, D.R.6
  • 58
    • 84859574757 scopus 로고    scopus 로고
    • Intellectual disability and major psychiatric disorders: A continuum of neurodevelopmental causality
    • M.J. Owen Intellectual disability and major psychiatric disorders: A continuum of neurodevelopmental causality Br J Psychiatry 200 2012 268 269
    • (2012) Br J Psychiatry , vol.200 , pp. 268-269
    • Owen, M.J.1
  • 59
    • 84856706805 scopus 로고    scopus 로고
    • Puzzling over schizophrenia: Schizophrenia as a pathway disease
    • P.F. Sullivan Puzzling over schizophrenia: schizophrenia as a pathway disease Nat Med 18 2012 210 211
    • (2012) Nat Med , vol.18 , pp. 210-211
    • Sullivan, P.F.1
  • 62
    • 0018119373 scopus 로고
    • A diagnostic interview: The schedule for affective disorders and schizophrenia
    • J. Endicott, and R.L. Spitzer A diagnostic interview: The schedule for affective disorders and schizophrenia Arch Gen Psychiatry 35 1978 837 844
    • (1978) Arch Gen Psychiatry , vol.35 , pp. 837-844
    • Endicott, J.1    Spitzer, R.L.2
  • 63
    • 0026769858 scopus 로고
    • The Structured Clinical Interview for DSM-III-R (SCID). 1. History, rationale, and description
    • R.L. Spitzer, J.B.W. Williams, M. Gibbon, and M.B. First The Structured Clinical Interview for DSM-III-R (SCID). 1. History, rationale, and description Arch Gen Psychiatry 49 1992 624 629
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 624-629
    • Spitzer, R.L.1    Williams, J.B.W.2    Gibbon, M.3    First, M.B.4
  • 64
    • 34347344976 scopus 로고    scopus 로고
    • A new multipoint method for genome-wide association studies by imputation of genotypes
    • J. Marchini, B. Howie, S. Myers, G. McVean, and P. Donnelly A new multipoint method for genome-wide association studies by imputation of genotypes Nat Genet 39 2007 906 913
    • (2007) Nat Genet , vol.39 , pp. 906-913
    • Marchini, J.1    Howie, B.2    Myers, S.3    McVean, G.4    Donnelly, P.5
  • 65
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Wellcome Trust Case Control Consortium Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls Nature 447 2007 661 U667
    • (2007) Nature , vol.447
  • 66
    • 24044550689 scopus 로고    scopus 로고
    • PEDSTATS: Descriptive statistics, graphics and quality assessment for gene mapping data
    • J.E. Wigginton, and G.R. Abecasis PEDSTATS: Descriptive statistics, graphics and quality assessment for gene mapping data Bioinformatics 21 2005 3445 3447
    • (2005) Bioinformatics , vol.21 , pp. 3445-3447
    • Wigginton, J.E.1    Abecasis, G.R.2
  • 68
    • 33846006923 scopus 로고    scopus 로고
    • Population structure and eigenanalysis
    • N. Patterson, A.L. Price, and D. Reich Population structure and eigenanalysis PLoS Genet 2 2006 e190
    • (2006) PLoS Genet , vol.2 , pp. 190
    • Patterson, N.1    Price, A.L.2    Reich, D.3
  • 69
    • 33746512512 scopus 로고    scopus 로고
    • Principal components analysis corrects for stratification in genome-wide association studies
    • A.L. Price, N.J. Patterson, R.M. Plenge, M.E. Weinblatt, N.A. Shadick, and D. Reich Principal components analysis corrects for stratification in genome-wide association studies Nat Genet 38 2006 904 909
    • (2006) Nat Genet , vol.38 , pp. 904-909
    • Price, A.L.1    Patterson, N.J.2    Plenge, R.M.3    Weinblatt, M.E.4    Shadick, N.A.5    Reich, D.6
  • 70
    • 0035528921 scopus 로고    scopus 로고
    • Genomic control, a new approach to genetic-based association studies
    • B. Devlin, K. Roeder, and L. Wasserman Genomic control, a new approach to genetic-based association studies Theor Popul Biol 60 2001 155 166
    • (2001) Theor Popul Biol , vol.60 , pp. 155-166
    • Devlin, B.1    Roeder, K.2    Wasserman, L.3
  • 71
    • 41649094148 scopus 로고    scopus 로고
    • Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data
    • F. Dudbridge Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data Hum Hered 66 2008 87 98
    • (2008) Hum Hered , vol.66 , pp. 87-98
    • Dudbridge, F.1
  • 72
    • 67249117049 scopus 로고    scopus 로고
    • Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
    • L.A. Hindorff, P. Sethupathy, H.A. Junkins, E.M. Ramos, J.P. Mehta, and F.S. Collins et al. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits Proc Natl Acad Sci 106 2009 9362 9367
    • (2009) Proc Natl Acad Sci , vol.106 , pp. 9362-9367
    • Hindorff, L.A.1    Sethupathy, P.2    Junkins, H.A.3    Ramos, E.M.4    Mehta, J.P.5    Collins, F.S.6
  • 73
    • 84975742565 scopus 로고    scopus 로고
    • A map of human genome variation from population-scale sequencing
    • The 1000 Genomes Project Consortium A map of human genome variation from population-scale sequencing Nature 467 2010 1061 1073
    • (2010) Nature , vol.467 , pp. 1061-1073
  • 76
    • 75749138608 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1
    • F.J. McMahon, N. Akula, T.G. Schulze, P. Muglia, F. Tozzi, and S.D. Detera-Wadleigh et al. Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1 Nat Genet 42 2010 128 131
    • (2010) Nat Genet , vol.42 , pp. 128-131
    • McMahon, F.J.1    Akula, N.2    Schulze, T.G.3    Muglia, P.4    Tozzi, F.5    Detera-Wadleigh, S.D.6
  • 77
    • 84858982485 scopus 로고    scopus 로고
    • Genome-wide association study of treatment refractory schizophrenia in Han Chinese
    • Y.-J. Liou, H.-H. Wang, M.-T.M. Lee, S.-C. Wang, H.-L. Chiang, and C.-C. Chen et al. Genome-wide association study of treatment refractory schizophrenia in Han Chinese PLoS One 7 2012 e33598
    • (2012) PLoS One , vol.7 , pp. 33598
    • Liou, Y.-J.1    Wang, H.-H.2    Lee, M.-T.M.3    Wang, S.-C.4    Chiang, H.-L.5    Chen, C.-C.6
  • 79
    • 77956903409 scopus 로고    scopus 로고
    • Common variants in major histocompatibility complex region and TCF4 gene are significantly associated with schizophrenia in Han Chinese
    • T. Li, Z. Li, P. Chen, Q. Zhao, T. Wang, and K. Huang et al. Common variants in major histocompatibility complex region and TCF4 gene are significantly associated with schizophrenia in Han Chinese Biol Psychiatry 68 2010 671 673
    • (2010) Biol Psychiatry , vol.68 , pp. 671-673
    • Li, T.1    Li, Z.2    Chen, P.3    Zhao, Q.4    Wang, T.5    Huang, K.6
  • 80
    • 82255175589 scopus 로고    scopus 로고
    • Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2
    • W.-H. Yue, H.-F. Wang, L.-D. Sun, F.-L. Tang, Z.-H. Liu, and H.-X. Zhang et al. Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2 Nat Genet 43 2011 1228 1231
    • (2011) Nat Genet , vol.43 , pp. 1228-1231
    • Yue, W.-H.1    Wang, H.-F.2    Sun, L.-D.3    Tang, F.-L.4    Liu, Z.-H.5    Zhang, H.-X.6
  • 81
    • 78249259373 scopus 로고    scopus 로고
    • A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder
    • K.-S. Wang, X.-F. Liu, and N. Aragam A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder Schizophr Res 124 2010 192 199
    • (2010) Schizophr Res , vol.124 , pp. 192-199
    • Wang, K.-S.1    Liu, X.-F.2    Aragam, N.3
  • 82
    • 84866358306 scopus 로고    scopus 로고
    • Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder
    • S.E. Bergen, C.T. O'Dushlaine, S. Ripke, P.H. Lee, D.M. Ruderfer, and S. Akterin et al. Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder Mol Psychiatry 17 2012 880 886
    • (2012) Mol Psychiatry , vol.17 , pp. 880-886
    • Bergen, S.E.1    O'Dushlaine, C.T.2    Ripke, S.3    Lee, P.H.4    Ruderfer, D.M.5    Akterin, S.6
  • 83
    • 67349153674 scopus 로고    scopus 로고
    • Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder
    • T.G. Schulze, S.D. Detera-Wadleigh, N. Akula, A. Gupta, L. Kassem, and J. Steele et al. Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder Mol Psychiatry 14 2009 487 491
    • (2009) Mol Psychiatry , vol.14 , pp. 487-491
    • Schulze, T.G.1    Detera-Wadleigh, S.D.2    Akula, N.3    Gupta, A.4    Kassem, L.5    Steele, J.6
  • 87
    • 84861528006 scopus 로고    scopus 로고
    • Association study of a new schizophrenia susceptibility locus of 10q24.32-33 in a Han Chinese population
    • F. Guan, S. Wei, J. Feng, C. Zhang, B. Xing, and H. Zhang et al. Association study of a new schizophrenia susceptibility locus of 10q24.32-33 in a Han Chinese population Schizophr Res 138 2012 63 68
    • (2012) Schizophr Res , vol.138 , pp. 63-68
    • Guan, F.1    Wei, S.2    Feng, J.3    Zhang, C.4    Xing, B.5    Zhang, H.6
  • 90
    • 38349128462 scopus 로고    scopus 로고
    • A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder
    • A.E. Baum, N. Akula, M. Cabanero, I. Cardona, W. Corona, and B. Klemens et al. A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder Mol Psychiatry 13 2007 197 207
    • (2007) Mol Psychiatry , vol.13 , pp. 197-207
    • Baum, A.E.1    Akula, N.2    Cabanero, M.3    Cardona, I.4    Corona, W.5    Klemens, B.6
  • 91
    • 42349094538 scopus 로고    scopus 로고
    • Meta-analysis of two genome-wide association studies of bipolar disorder reveals important points of agreement
    • A.E. Baum, M. Hamshere, E. Green, S. Cichon, M. Rietschel, and M.M. Noethen et al. Meta-analysis of two genome-wide association studies of bipolar disorder reveals important points of agreement Mol Psychiatry 13 2008 466 467
    • (2008) Mol Psychiatry , vol.13 , pp. 466-467
    • Baum, A.E.1    Hamshere, M.2    Green, E.3    Cichon, S.4    Rietschel, M.5    Noethen, M.M.6
  • 93
    • 62849086589 scopus 로고    scopus 로고
    • Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort
    • H.M. Ollila, P. Soronen, K. Silander, O.M. Palo, T. Kieseppa, and M.A. Kaunisto et al. Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort Mol Psychiatry 14 2008 351 353
    • (2008) Mol Psychiatry , vol.14 , pp. 351-353
    • Ollila, H.M.1    Soronen, P.2    Silander, K.3    Palo, O.M.4    Kieseppa, T.5    Kaunisto, M.A.6
  • 95
    • 84861527496 scopus 로고    scopus 로고
    • Association between schizophrenia and common variation in neurocan (NCAN), a genetic risk factor for bipolar disorder
    • T.W. Mühleisen, M. Mattheisen, J. Strohmaier, F. Degenhardt, L. Priebe, and C.C. Schultz et al. Association between schizophrenia and common variation in neurocan (NCAN), a genetic risk factor for bipolar disorder Schizophr Res 138 2012 69 73
    • (2012) Schizophr Res , vol.138 , pp. 69-73
    • Mühleisen, T.W.1    Mattheisen, M.2    Strohmaier, J.3    Degenhardt, F.4    Priebe, L.5    Schultz, C.C.6
  • 96
    • 0034060459 scopus 로고    scopus 로고
    • Twin studies of schizophrenia: From bow-and-arrow concordances to star wars mx and functional genomics
    • A. Cardno, and I. Gottesman Twin studies of schizophrenia: From bow-and-arrow concordances to star wars mx and functional genomics Am J Med Genet B Neuropsychiatr Genet 97 2000 12 17
    • (2000) Am J Med Genet B Neuropsychiatr Genet , vol.97 , pp. 12-17
    • Cardno, A.1    Gottesman, I.2
  • 98
    • 0344305525 scopus 로고    scopus 로고
    • Schizophrenia as a complex trait - Evidence from a meta-analysis of twin studies
    • P.F. Sullivan, K.S. Kendler, and M.C. Neale Schizophrenia as a complex trait - evidence from a meta-analysis of twin studies Arch Gen Psychiatry 60 2003 1187 1192
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 1187-1192
    • Sullivan, P.F.1    Kendler, K.S.2    Neale, M.C.3
  • 99
    • 34248193787 scopus 로고    scopus 로고
    • Gene polymorphisms and behavior
    • P. McGuffin Gene polymorphisms and behavior Pediatr Blood Cancer 48 2007 736 737
    • (2007) Pediatr Blood Cancer , vol.48 , pp. 736-737
    • McGuffin, P.1
  • 100
    • 58149464318 scopus 로고    scopus 로고
    • Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: A population-based study
    • P. Lichtenstein, B.H. Yip, C. Bjork, Y. Pawitan, T.D. Cannon, and P.F. Sullivan et al. Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: A population-based study Lancet 373 2009 234 239
    • (2009) Lancet , vol.373 , pp. 234-239
    • Lichtenstein, P.1    Yip, B.H.2    Bjork, C.3    Pawitan, Y.4    Cannon, T.D.5    Sullivan, P.F.6
  • 101
    • 77951131269 scopus 로고    scopus 로고
    • Mendelian disorders and multifactorial traits: The big divide or one for all?
    • S.E. Antonarakis, A. Chakravarti, J.C. Cohen, and J. Hardy Mendelian disorders and multifactorial traits: The big divide or one for all? Nat Rev Genet 11 2010 380 384
    • (2010) Nat Rev Genet , vol.11 , pp. 380-384
    • Antonarakis, S.E.1    Chakravarti, A.2    Cohen, J.C.3    Hardy, J.4
  • 102
    • 40449131639 scopus 로고    scopus 로고
    • Whole genome association studies: Deciding when persistence becomes perseveration
    • J. Hardy, N. Low, and A. Singleton Whole genome association studies: deciding when persistence becomes perseveration Am J Med Genet B Neuropsychiatr Genet 147B 2008 131 133
    • (2008) Am J Med Genet B Neuropsychiatr Genet , vol.147 B , pp. 131-133
    • Hardy, J.1    Low, N.2    Singleton, A.3
  • 103
    • 79955578449 scopus 로고    scopus 로고
    • Genes and environment in psychiatry: Winner's curse or cure?
    • J. Hardy, and N.C. Low Genes and environment in psychiatry: Winner's curse or cure? Arch Gen Psychiatry 68 2011 455 456
    • (2011) Arch Gen Psychiatry , vol.68 , pp. 455-456
    • Hardy, J.1    Low, N.C.2
  • 104
    • 77954513019 scopus 로고    scopus 로고
    • Suggestion of roles for both common and rare risk variants in genome-wide studies of schizophrenia
    • M.J. Owen, N. Craddock, and M.C. O'Donovan Suggestion of roles for both common and rare risk variants in genome-wide studies of schizophrenia Arch Gen Psychiatry 67 2010 667 673
    • (2010) Arch Gen Psychiatry , vol.67 , pp. 667-673
    • Owen, M.J.1    Craddock, N.2    O'Donovan, M.C.3
  • 105
    • 84863393715 scopus 로고    scopus 로고
    • Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke
    • C. Bellenguez, S. Bevan, A. Gschwendtner, C.C. Spencer, A.I. Burgess, and M. Pirinen et al. Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke Nat Genet 44 2012 328 333
    • (2012) Nat Genet , vol.44 , pp. 328-333
    • Bellenguez, C.1    Bevan, S.2    Gschwendtner, A.3    Spencer, C.C.4    Burgess, A.I.5    Pirinen, M.6
  • 106
    • 80051684615 scopus 로고    scopus 로고
    • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
    • S. Sawcer, G. Hellenthal, M. Pirinen, C.C. Spencer, N.A. Patsopoulos, and L. Moutsianas et al. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis Nature 476 2011 214 219
    • (2011) Nature , vol.476 , pp. 214-219
    • Sawcer, S.1    Hellenthal, G.2    Pirinen, M.3    Spencer, C.C.4    Patsopoulos, N.A.5    Moutsianas, L.6
  • 107
    • 78650550275 scopus 로고    scopus 로고
    • Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21
    • C.C. Spencer, V. Plagnol, A. Strange, M. Gardner, C. Paisan-Ruiz, and G. Band et al. Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21 Hum Mol Genet 20 2011 345 353
    • (2011) Hum Mol Genet , vol.20 , pp. 345-353
    • Spencer, C.C.1    Plagnol, V.2    Strange, A.3    Gardner, M.4    Paisan-Ruiz, C.5    Band, G.6
  • 108
    • 60149102060 scopus 로고    scopus 로고
    • Size matters: Just how big is BIG?: Quantifying realistic sample size requirements for human genome epidemiology
    • P.R. Burton, A.L. Hansell, I. Fortier, T.A. Manolio, M.J. Khoury, and J. Little et al. Size matters: Just how big is BIG?: Quantifying realistic sample size requirements for human genome epidemiology Int J Epidemiol 38 2009 263 273
    • (2009) Int J Epidemiol , vol.38 , pp. 263-273
    • Burton, P.R.1    Hansell, A.L.2    Fortier, I.3    Manolio, T.A.4    Khoury, M.J.5    Little, J.6
  • 109
    • 66149185456 scopus 로고    scopus 로고
    • Genomewide association studies: History, rationale, and prospects for psychiatric disorders
    • S. Cichon, N. Craddock, M. Daly, S.V. Faraone, P.V. Gejman, and J. Kelsoe et al. Genomewide association studies: History, rationale, and prospects for psychiatric disorders Am J Psychiatry 166 2009 540 556
    • (2009) Am J Psychiatry , vol.166 , pp. 540-556
    • Cichon, S.1    Craddock, N.2    Daly, M.3    Faraone, S.V.4    Gejman, P.V.5    Kelsoe, J.6
  • 112
    • 79953057217 scopus 로고    scopus 로고
    • Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia
    • V. Vacic, S. McCarthy, D. Malhotra, F. Murray, H.H. Chou, and A. Peoples et al. Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia Nature 471 2011 499 503
    • (2011) Nature , vol.471 , pp. 499-503
    • Vacic, V.1    McCarthy, S.2    Malhotra, D.3    Murray, F.4    Chou, H.H.5    Peoples, A.6
  • 114
    • 50549104256 scopus 로고    scopus 로고
    • Why most discovered true associations are inflated
    • J.P. Ioannidis Why most discovered true associations are inflated Epidemiology 19 2008 640 648
    • (2008) Epidemiology , vol.19 , pp. 640-648
    • Ioannidis, J.P.1
  • 115
    • 34147119077 scopus 로고    scopus 로고
    • Overcoming the winner's curse: Estimating penetrance parameters from case-control data
    • S. Zollner, and J.K. Pritchard Overcoming the winner's curse: Estimating penetrance parameters from case-control data Am J Hum Genet 80 2007 605 615
    • (2007) Am J Hum Genet , vol.80 , pp. 605-615
    • Zollner, S.1    Pritchard, J.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.