메뉴 건너뛰기




Volumn 32, Issue 1, 2014, Pages 1-9

Role of local vitamin D signaling and cellular calcium transport system in bone homeostasis

Author keywords

Calcium absorption; Osteoclasts; Transient receptor potential vanilloid; TRPV; Vitamin D receptor

Indexed keywords

25 HYDROXYVITAMIN D; CALCIUM; CALCIUM CHANNEL; VANILLOID RECEPTOR 4;

EID: 84893784295     PISSN: 09148779     EISSN: 14355604     Source Type: Journal    
DOI: 10.1007/s00774-013-0508-z     Document Type: Review
Times cited : (22)

References (56)
  • 2
    • 0030610422 scopus 로고    scopus 로고
    • Targeted ablation of the vitamin D receptor: An animal model of vitamin D-dependent rickets type II with alopecia
    • 1:CAS:528:DyaK2sXlvVWls7Y%3D 9275211 10.1073/pnas.94.18.9831
    • Li YC, Pirro AE, Amling M, Delling G, Baron R, Bronson R, Demay MB (1997) Targeted ablation of the vitamin D receptor: an animal model of vitamin D-dependent rickets type II with alopecia. Proc Natl Acad Sci USA 94:9831-9835
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 9831-9835
    • Li, Y.C.1    Pirro, A.E.2    Amling, M.3    Delling, G.4    Baron, R.5    Bronson, R.6    Demay, M.B.7
  • 4
    • 85047685376 scopus 로고    scopus 로고
    • Deletion of deoxyribonucleic acid binding domain of the vitamin D receptor abrogates genomic and nongenomic functions of vitamin D
    • 1:CAS:528:DC%2BD38XlsVGitbg%3D 12089348
    • Erben RG, Soegiarto DW, Weber K, Zeitz U, Lieberherr M, Gniadecki R, Moller G, Adamski J, Balling R (2002) Deletion of deoxyribonucleic acid binding domain of the vitamin D receptor abrogates genomic and nongenomic functions of vitamin D. Mol Endocrinol 16:1524-1537
    • (2002) Mol Endocrinol , vol.16 , pp. 1524-1537
    • Erben, R.G.1    Soegiarto, D.W.2    Weber, K.3    Zeitz, U.4    Lieberherr, M.5    Gniadecki, R.6    Moller, G.7    Adamski, J.8    Balling, R.9
  • 5
    • 0034984919 scopus 로고    scopus 로고
    • Targeted inactivation of the 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase gene (CYP27B1) creates an animal model of pseudovitamin D-deficiency rickets
    • 1:CAS:528:DC%2BD3MXkslelt7g%3D 11416036
    • Dardenne O, Prud'homme J, Arabian A, Glorieux FH, St-Arnaud R (2001) Targeted inactivation of the 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase gene (CYP27B1) creates an animal model of pseudovitamin D-deficiency rickets. Endocrinology 142:3135-3141
    • (2001) Endocrinology , vol.142 , pp. 3135-3141
    • Dardenne, O.1    Prud'Homme, J.2    Arabian, A.3    Glorieux, F.H.4    St-Arnaud, R.5
  • 6
    • 0035912707 scopus 로고    scopus 로고
    • Targeted ablation of the 25-hydroxyvitamin D 1alpha -hydroxylase enzyme: Evidence for skeletal, reproductive, and immune dysfunction
    • 1:CAS:528:DC%2BD3MXkslWlsrY%3D 11416220 10.1073/pnas.131029498
    • Panda DK, Miao D, Tremblay ML, Sirois J, Farookhi R, Hendy GN, Goltzman D (2001) Targeted ablation of the 25-hydroxyvitamin D 1alpha -hydroxylase enzyme: evidence for skeletal, reproductive, and immune dysfunction. Proc Natl Acad Sci USA 98:7498-7503
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 7498-7503
    • Panda, D.K.1    Miao, D.2    Tremblay, M.L.3    Sirois, J.4    Farookhi, R.5    Hendy, G.N.6    Goltzman, D.7
  • 8
    • 78650705554 scopus 로고    scopus 로고
    • Molecular mechanisms for regulation of intestinal calcium absorption by vitamin D and other factors
    • 1:CAS:528:DC%2BC3cXhs1Srt7vJ 3235806 21182397 10.3109/10408363.2010. 536429
    • Fleet JC, Schoch RD (2010) Molecular mechanisms for regulation of intestinal calcium absorption by vitamin D and other factors. Crit Rev Clin Lab Sci 47:181-195
    • (2010) Crit Rev Clin Lab Sci , vol.47 , pp. 181-195
    • Fleet, J.C.1    Schoch, R.D.2
  • 12
    • 14044249546 scopus 로고    scopus 로고
    • Convergent signaling by acidosis and receptor activator of NF-kappaB ligand (RANKL) on the calcium/calcineurin/NFAT pathway in osteoclasts
    • 1:CAS:528:DC%2BD2MXhvFKhsrw%3D 15695591 10.1073/pnas.0406874102
    • Komarova SV, Pereverzev A, Shum JW, Sims SM, Dixon SJ (2005) Convergent signaling by acidosis and receptor activator of NF-kappaB ligand (RANKL) on the calcium/calcineurin/NFAT pathway in osteoclasts. Proc Natl Acad Sci USA 102:2643-2648
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 2643-2648
    • Komarova, S.V.1    Pereverzev, A.2    Shum, J.W.3    Sims, S.M.4    Dixon, S.J.5
  • 13
    • 80052229506 scopus 로고    scopus 로고
    • Calcemic actions of vitamin D: Effects on the intestine, kidney and bone
    • 1:CAS:528:DC%2BC3MXhtFSru7jO 21872798 10.1016/j.beem.2011.05.008
    • Lieben L, Carmeliet G, Masuyama R (2011) Calcemic actions of vitamin D: effects on the intestine, kidney and bone. Best Pract Res Clin Endocrinol Metab 25:561-572
    • (2011) Best Pract Res Clin Endocrinol Metab , vol.25 , pp. 561-572
    • Lieben, L.1    Carmeliet, G.2    Masuyama, R.3
  • 15
    • 62949178699 scopus 로고    scopus 로고
    • Intestinal vitamin D receptor is required for normal calcium and bone metabolism in mice
    • e1311-1312
    • Xue Y, Fleet JC (2009) Intestinal vitamin D receptor is required for normal calcium and bone metabolism in mice. Gastroenterology 136:1317-1327, e1311-1312
    • (2009) Gastroenterology , vol.136 , pp. 1317-1327
    • Xue, Y.1    Fleet, J.C.2
  • 16
    • 84866705387 scopus 로고    scopus 로고
    • Villin promoter-mediated transgenic expression of transient receptor potential cation channel, subfamily V, member 6 (TRPV6) increases intestinal calcium absorption in wild-type and vitamin D receptor knockout mice
    • 1:CAS:528:DC%2BC38XhtlKjt7%2FM 3430830 22589201 10.1002/jbmr.1662
    • Cui M, Li Q, Johnson R, Fleet JC (2012) Villin promoter-mediated transgenic expression of transient receptor potential cation channel, subfamily V, member 6 (TRPV6) increases intestinal calcium absorption in wild-type and vitamin D receptor knockout mice. J Bone Miner Res 27:2097-2107
    • (2012) J Bone Miner Res , vol.27 , pp. 2097-2107
    • Cui, M.1    Li, Q.2    Johnson, R.3    Fleet, J.C.4
  • 17
    • 0022462199 scopus 로고
    • Long-term nocturnal calcium infusions can cure rickets and promote normal mineralization in hereditary resistance to 1,25-dihydroxyvitamin D
    • 1:STN:280:DyaL287ps1Ohtw%3D%3D 424571 3009551 10.1172/JCI112483
    • Balsan S, Garabedian M, Larchet M, Gorski AM, Cournot G, Tau C, Bourdeau A, Silve C, Ricour C (1986) Long-term nocturnal calcium infusions can cure rickets and promote normal mineralization in hereditary resistance to 1,25-dihydroxyvitamin D. J Clin Invest 77:1661-1667
    • (1986) J Clin Invest , vol.77 , pp. 1661-1667
    • Balsan, S.1    Garabedian, M.2    Larchet, M.3    Gorski, A.M.4    Cournot, G.5    Tau, C.6    Bourdeau, A.7    Silve, C.8    Ricour, C.9
  • 18
    • 0032780531 scopus 로고    scopus 로고
    • The vitamin D receptor and the syndrome of hereditary 1,25-dihydroxyvitamin D-resistant rickets
    • 1:CAS:528:DyaK1MXisFygsrg%3D 10204116
    • Malloy PJ, Pike JW, Feldman D (1999) The vitamin D receptor and the syndrome of hereditary 1,25-dihydroxyvitamin D-resistant rickets. Endocr Rev 20:156-188
    • (1999) Endocr Rev , vol.20 , pp. 156-188
    • Malloy, P.J.1    Pike, J.W.2    Feldman, D.3
  • 19
    • 0000524953 scopus 로고    scopus 로고
    • Normalization of mineral ion homeostasis by dietary means prevents hyperparathyroidism, rickets, and osteomalacia, but not alopecia in vitamin D receptor-ablated mice
    • 1:CAS:528:DyaK1cXmsVGms7Y%3D 9751523
    • Li YC, Amling M, Pirro AE, Priemel M, Meuse J, Baron R, Delling G, Demay MB (1998) Normalization of mineral ion homeostasis by dietary means prevents hyperparathyroidism, rickets, and osteomalacia, but not alopecia in vitamin D receptor-ablated mice. Endocrinology 139:4391-4396
    • (1998) Endocrinology , vol.139 , pp. 4391-4396
    • Li, Y.C.1    Amling, M.2    Pirro, A.E.3    Priemel, M.4    Meuse, J.5    Baron, R.6    Delling, G.7    Demay, M.B.8
  • 21
    • 10744224186 scopus 로고    scopus 로고
    • Dietary calcium and phosphorus ratio regulates bone mineralization and turnover in vitamin D receptor knockout mice by affecting intestinal calcium and phosphorus absorption
    • 1:CAS:528:DC%2BD3sXlsFGktLw%3D 12854831 10.1359/jbmr.2003.18.7.1217
    • Masuyama R, Nakaya Y, Katsumata S, Kajita Y, Uehara M, Tanaka S, Sakai A, Kato S, Nakamura T, Suzuki K (2003) Dietary calcium and phosphorus ratio regulates bone mineralization and turnover in vitamin D receptor knockout mice by affecting intestinal calcium and phosphorus absorption. J Bone Miner Res 18:1217-1226
    • (2003) J Bone Miner Res , vol.18 , pp. 1217-1226
    • Masuyama, R.1    Nakaya, Y.2    Katsumata, S.3    Kajita, Y.4    Uehara, M.5    Tanaka, S.6    Sakai, A.7    Kato, S.8    Nakamura, T.9    Suzuki, K.10
  • 25
    • 57149120511 scopus 로고    scopus 로고
    • Modulation of mouse RANKL gene expression by Runx2 and vitamin D3
    • 1:CAS:528:DC%2BD1cXhsFWgt7%2FJ 18814144 10.1002/jcb.21929
    • Kitazawa R, Mori K, Yamaguchi A, Kondo T, Kitazawa S (2008) Modulation of mouse RANKL gene expression by Runx2 and vitamin D3. J Cell Biochem 105:1289-1297
    • (2008) J Cell Biochem , vol.105 , pp. 1289-1297
    • Kitazawa, R.1    Mori, K.2    Yamaguchi, A.3    Kondo, T.4    Kitazawa, S.5
  • 26
    • 0038754646 scopus 로고    scopus 로고
    • Stimulation of osteoclast formation by 1,25-dihydroxyvitamin D requires its binding to vitamin D receptor (VDR) in osteoblastic cells: Studies using VDR knockout mice
    • 1:CAS:528:DyaK1MXntl2lug%3D%3D 9927335
    • Takeda S, Yoshizawa T, Nagai Y, Yamato H, Fukumoto S, Sekine K, Kato S, Matsumoto T, Fujita T (1999) Stimulation of osteoclast formation by 1,25-dihydroxyvitamin D requires its binding to vitamin D receptor (VDR) in osteoblastic cells: studies using VDR knockout mice. Endocrinology 140:1005-1008
    • (1999) Endocrinology , vol.140 , pp. 1005-1008
    • Takeda, S.1    Yoshizawa, T.2    Nagai, Y.3    Yamato, H.4    Fukumoto, S.5    Sekine, K.6    Kato, S.7    Matsumoto, T.8    Fujita, T.9
  • 27
    • 0033303655 scopus 로고    scopus 로고
    • Rescue of the skeletal phenotype of vitamin D receptor-ablated mice in the setting of normal mineral ion homeostasis: Formal histomorphometric and biomechanical analyses
    • 1:CAS:528:DyaK1MXmvFemsLY%3D 10537122
    • Amling M, Priemel M, Holzmann T, Chapin K, Rueger JM, Baron R, Demay MB (1999) Rescue of the skeletal phenotype of vitamin D receptor-ablated mice in the setting of normal mineral ion homeostasis: formal histomorphometric and biomechanical analyses. Endocrinology 140:4982-4987
    • (1999) Endocrinology , vol.140 , pp. 4982-4987
    • Amling, M.1    Priemel, M.2    Holzmann, T.3    Chapin, K.4    Rueger, J.M.5    Baron, R.6    Demay, M.B.7
  • 28
    • 0037384951 scopus 로고    scopus 로고
    • Correction of the abnormal mineral ion homeostasis with a high-calcium, high-phosphorus, high-lactose diet rescues the PDDR phenotype of mice deficient for the 25-hydroxyvitamin D-1alpha-hydroxylase (CYP27B1)
    • 1:CAS:528:DC%2BD3sXislenu7Y%3D 12689675 10.1016/S8756-3282(03)00023-1
    • Dardenne O, Prud'homme J, Hacking SA, Glorieux FH, St-Arnaud R (2003) Correction of the abnormal mineral ion homeostasis with a high-calcium, high-phosphorus, high-lactose diet rescues the PDDR phenotype of mice deficient for the 25-hydroxyvitamin D-1alpha-hydroxylase (CYP27B1). Bone 32:332-340
    • (2003) Bone , vol.32 , pp. 332-340
    • Dardenne, O.1    Prud'Homme, J.2    Hacking, S.A.3    Glorieux, F.H.4    St-Arnaud, R.5
  • 29
    • 1942469303 scopus 로고    scopus 로고
    • Inactivation of the 25-hydroxyvitamin D 1α-hydroxylase and vitamin D receptor demonstrates independent and interdependent effects of calcium and vitamin D on skeletal and mineral homeostasis
    • 1:CAS:528:DC%2BD2cXivF2qu7k%3D 14739296 10.1074/jbc.M310271200
    • Panda DK, Miao D, Bolivar I, Li J, Huo R, Hendy GN, Goltzman D (2004) Inactivation of the 25-hydroxyvitamin D 1α-hydroxylase and vitamin D receptor demonstrates independent and interdependent effects of calcium and vitamin D on skeletal and mineral homeostasis. J Biol Chem 279:16754-16766
    • (2004) J Biol Chem , vol.279 , pp. 16754-16766
    • Panda, D.K.1    Miao, D.2    Bolivar, I.3    Li, J.4    Huo, R.5    Hendy, G.N.6    Goltzman, D.7
  • 30
    • 67649877960 scopus 로고    scopus 로고
    • Hyperparathyroidism
    • 1:CAS:528:DC%2BD1MXotl2ks7k%3D 19595349 10.1016/S0140-6736(09)60507-9
    • Fraser WD (2009) Hyperparathyroidism. Lancet 374:145-158
    • (2009) Lancet , vol.374 , pp. 145-158
    • Fraser, W.D.1
  • 31
    • 33747792713 scopus 로고    scopus 로고
    • Parathyroid hormone controls receptor activator of NF-κB ligand gene expression via a distant transcriptional enhancer
    • 1:CAS:528:DC%2BD28XovFyhu7s%3D 1592840 16914731 10.1128/MCB.00356-06
    • Fu Q, Manolagas SC, O'Brien CA (2006) Parathyroid hormone controls receptor activator of NF-κB ligand gene expression via a distant transcriptional enhancer. Mol Cell Biol 26:6453-6468
    • (2006) Mol Cell Biol , vol.26 , pp. 6453-6468
    • Fu, Q.1    Manolagas, S.C.2    O'Brien, C.A.3
  • 32
    • 33747787316 scopus 로고    scopus 로고
    • Activation of receptor activator of NF-kappaB ligand gene expression by 1,25-dihydroxyvitamin D3 is mediated through multiple long-range enhancers
    • 1:CAS:528:DC%2BD28XovFyhu7g%3D 1592822 16914732 10.1128/MCB.00353-06
    • Kim S, Yamazaki M, Zella LA, Shevde NK, Pike JW (2006) Activation of receptor activator of NF-kappaB ligand gene expression by 1,25-dihydroxyvitamin D3 is mediated through multiple long-range enhancers. Mol Cell Biol 26:6469-6486
    • (2006) Mol Cell Biol , vol.26 , pp. 6469-6486
    • Kim, S.1    Yamazaki, M.2    Zella, L.A.3    Shevde, N.K.4    Pike, J.W.5
  • 33
    • 37549006425 scopus 로고    scopus 로고
    • Targeted deletion of a distant transcriptional enhancer of the receptor activator of nuclear factor-kappaB ligand gene reduces bone remodeling and increases bone mass
    • 1:CAS:528:DC%2BD1cXjtVyhtQ%3D%3D 17932217 10.1210/en.2007-0734
    • Galli C, Zella LA, Fretz JA, Fu Q, Pike JW, Weinstein RS, Manolagas SC, O'Brien CA (2008) Targeted deletion of a distant transcriptional enhancer of the receptor activator of nuclear factor-kappaB ligand gene reduces bone remodeling and increases bone mass. Endocrinology 149:146-153
    • (2008) Endocrinology , vol.149 , pp. 146-153
    • Galli, C.1    Zella, L.A.2    Fretz, J.A.3    Fu, Q.4    Pike, J.W.5    Weinstein, R.S.6    Manolagas, S.C.7    O'Brien, C.A.8
  • 34
    • 84874593853 scopus 로고    scopus 로고
    • Vitamin D receptor in osteoblasts is a negative regulator of bone mass control
    • 1:CAS:528:DC%2BC3sXjsF2rsb4%3D 23389957 10.1210/en.2012-1542
    • Yamamoto Y, Yoshizawa T, Fukuda T, Shirode-Fukuda Y, Yu T, et al (2013) Vitamin D receptor in osteoblasts is a negative regulator of bone mass control. Endocrinology 154:1008-1020
    • (2013) Endocrinology , vol.154 , pp. 1008-1020
    • Yamamoto, Y.1    Yoshizawa, T.2    Fukuda, T.3    Shirode-Fukuda, Y.4    Yu, T.5
  • 37
    • 21644452584 scopus 로고    scopus 로고
    • Osteoblasts lacking the vitamin D receptor display enhanced osteogenic potential in vitro
    • 1:CAS:528:DC%2BD2MXmvFCl 15517598 10.1002/jcb.20313
    • Sooy K, Sabbagh Y, Demay MB (2005) Osteoblasts lacking the vitamin D receptor display enhanced osteogenic potential in vitro. J Cell Biochem 94:81-87
    • (2005) J Cell Biochem , vol.94 , pp. 81-87
    • Sooy, K.1    Sabbagh, Y.2    Demay, M.B.3
  • 38
    • 0038125598 scopus 로고    scopus 로고
    • Calcium signalling: Dynamics, homeostasis and remodelling
    • 1:CAS:528:DC%2BD3sXltVWmsr8%3D 12838335 10.1038/nrm1155
    • Berridge MJ, Bootman MD, Roderick HL (2003) Calcium signalling: dynamics, homeostasis and remodelling. Nat Rev Mol Cell Biol 4:517-529
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 517-529
    • Berridge, M.J.1    Bootman, M.D.2    Roderick, H.L.3
  • 39
    • 0043267987 scopus 로고    scopus 로고
    • Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels
    • 1:CAS:528:DC%2BD3sXls1aqsbs%3D 12879072 10.1038/nature01807
    • Watanabe H, Vriens J, Prenen J, Droogmans G, Voets T, Nilius B (2003) Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels. Nature 424:434-438
    • (2003) Nature , vol.424 , pp. 434-438
    • Watanabe, H.1    Vriens, J.2    Prenen, J.3    Droogmans, G.4    Voets, T.5    Nilius, B.6
  • 40
    • 0347719316 scopus 로고    scopus 로고
    • Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4
    • 1:CAS:528:DC%2BD2cXjvFaksQ%3D%3D 14691263 10.1073/pnas.0303329101
    • Vriens J, Watanabe H, Janssens A, Droogmans G, Voets T, Nilius B (2004) Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4. Proc Natl Acad Sci USA 101:396-401
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 396-401
    • Vriens, J.1    Watanabe, H.2    Janssens, A.3    Droogmans, G.4    Voets, T.5    Nilius, B.6
  • 42
    • 0038604287 scopus 로고    scopus 로고
    • Impaired pressure sensation in mice lacking TRPV4
    • 1:CAS:528:DC%2BD3sXksF2it7s%3D 12692122 10.1074/jbc.M302561200
    • Suzuki M, Mizuno A, Kodaira K, Imai M (2003) Impaired pressure sensation in mice lacking TRPV4. J Biol Chem 278:22664-22668
    • (2003) J Biol Chem , vol.278 , pp. 22664-22668
    • Suzuki, M.1    Mizuno, A.2    Kodaira, K.3    Imai, M.4
  • 44
    • 77952748007 scopus 로고    scopus 로고
    • Novel and recurrent TRPV4 mutations and their association with distinct phenotypes within the TRPV4 dysplasia family
    • Dai J, Kim OH, Cho TJ, Schmidt-Rimpler M, Tonoki H, et al (2010) Novel and recurrent TRPV4 mutations and their association with distinct phenotypes within the TRPV4 dysplasia family. J Med Genet 47:704-709
    • (2010) J Med Genet , vol.47 , pp. 704-709
    • Dai, J.1    Kim, O.H.2    Cho, T.J.3    Schmidt-Rimpler, M.4    Tonoki, H.5
  • 45
    • 75749129360 scopus 로고    scopus 로고
    • Alterations in the ankyrin domain of TRPV4 cause congenital distal SMA, scapuloperoneal SMA and HMSN2C
    • 1:CAS:528:DC%2BD1MXhs1SktbvL 3272392 20037588 10.1038/ng.508
    • Auer-Grumbach M, Olschewski A, Papic L, Kremer H, McEntagart ME, et al (2010) Alterations in the ankyrin domain of TRPV4 cause congenital distal SMA, scapuloperoneal SMA and HMSN2C. Nat Genet 42:160-164
    • (2010) Nat Genet , vol.42 , pp. 160-164
    • Auer-Grumbach, M.1    Olschewski, A.2    Papic, L.3    Kremer, H.4    McEntagart, M.E.5
  • 47
    • 75749139617 scopus 로고    scopus 로고
    • Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C
    • 1:CAS:528:DC%2BD1MXhs1Skur%2FM 2812627 20037586 10.1038/ng.512
    • Landoure G, Zdebik AA, Martinez TL, Burnett BG, Stanescu HC, et al (2010) Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C. Nat Genet 42:170-174
    • (2010) Nat Genet , vol.42 , pp. 170-174
    • Landoure, G.1    Zdebik, A.A.2    Martinez, T.L.3    Burnett, B.G.4    Stanescu, H.C.5
  • 50
    • 78649443616 scopus 로고    scopus 로고
    • RANKL-induced TRPV2 expression regulates osteoclastogenesis via calcium oscillations
    • 1:CAS:528:DC%2BC3cXhsVyhsLjN 20980052 10.1016/j.ceca.2010.09.010
    • Kajiya H, Okamoto F, Nemoto T, Kimachi K, Toh-Goto K, Nakayana S, Okabe K (2010) RANKL-induced TRPV2 expression regulates osteoclastogenesis via calcium oscillations. Cell Calcium 48:260-269
    • (2010) Cell Calcium , vol.48 , pp. 260-269
    • Kajiya, H.1    Okamoto, F.2    Nemoto, T.3    Kimachi, K.4    Toh-Goto, K.5    Nakayana, S.6    Okabe, K.7
  • 51
    • 0038609734 scopus 로고    scopus 로고
    • Structural determinant of TRPV1 desensitization interacts with calmodulin
    • 1:CAS:528:DC%2BD3sXlt1WqtL8%3D 12808128 10.1073/pnas.1337252100
    • Numazaki M, Tominaga T, Takeuchi K, Murayama N, Toyooka H, Tominaga M (2003) Structural determinant of TRPV1 desensitization interacts with calmodulin. Proc Natl Acad Sci USA 100:8002-8006
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8002-8006
    • Numazaki, M.1    Tominaga, T.2    Takeuchi, K.3    Murayama, N.4    Toyooka, H.5    Tominaga, M.6
  • 52
    • 77957726026 scopus 로고    scopus 로고
    • 2+-dependent desensitization of TRPV2 channels is mediated by hydrolysis of phosphatidylinositol 4,5-bisphosphate
    • 1:CAS:528:DC%2BC3cXhtlars7bE 3001133 20926660 10.1523/JNEUROSCI.2108-10. 2010
    • 2+-dependent desensitization of TRPV2 channels is mediated by hydrolysis of phosphatidylinositol 4,5-bisphosphate. J Neurosci 30:13338-13347
    • (2010) J Neurosci , vol.30 , pp. 13338-13347
    • Mercado, J.1    Gordon-Shaag, A.2    Zagotta, W.N.3    Gordon, S.E.4
  • 54
    • 30044448541 scopus 로고    scopus 로고
    • Calmodulin is a critical regulator of osteoclastic differentiation, function, and survival
    • 1:CAS:528:DC%2BD28XivV2lsA%3D%3D 16216008 10.1002/jcb.20659
    • Seales EC, Micoli KJ, McDonald JM (2006) Calmodulin is a critical regulator of osteoclastic differentiation, function, and survival. J Cell Biochem 97:45-55
    • (2006) J Cell Biochem , vol.97 , pp. 45-55
    • Seales, E.C.1    Micoli, K.J.2    McDonald, J.M.3
  • 55
    • 23844504243 scopus 로고    scopus 로고
    • Fas binding to calmodulin regulates apoptosis in osteoclasts
    • 1:CAS:528:DC%2BD2MXns1SltLg%3D 1351015 15965236 10.1074/jbc.M500710200
    • Wu X, Ahn EY, McKenna MA, Yeo H, McDonald JM (2005) Fas binding to calmodulin regulates apoptosis in osteoclasts. J Biol Chem 280:29964-29970
    • (2005) J Biol Chem , vol.280 , pp. 29964-29970
    • Wu, X.1    Ahn, E.Y.2    McKenna, M.A.3    Yeo, H.4    McDonald, J.M.5
  • 56


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.