-
1
-
-
18744366041
-
Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts
-
Takayanagi H., Kim S., Koga T., Nishina H., Isshiki M., Yoshida H., Saiura A., Isobe M., Yokochi T., Inoue J., Wagner E.F., Mak T.W., Kodama T., Taniguchi T. Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. Dev. Cell 2002, 3:889-901.
-
(2002)
Dev. Cell
, vol.3
, pp. 889-901
-
-
Takayanagi, H.1
Kim, S.2
Koga, T.3
Nishina, H.4
Isshiki, M.5
Yoshida, H.6
Saiura, A.7
Isobe, M.8
Yokochi, T.9
Inoue, J.10
Wagner, E.F.11
Mak, T.W.12
Kodama, T.13
Taniguchi, T.14
-
2
-
-
33845539490
-
Regulation of osteoclast differentiation and function by the CaMK-CREB pathway
-
Sato K., Suematsu A., Nakashima T., Takemoto-Kimura S., Aoki K., Morishita Y., Asahara H., Ohya K., Yamaguchi A., Takai T., Kodama T., Chatila T.A., Bito H., Takayanagi H. Regulation of osteoclast differentiation and function by the CaMK-CREB pathway. Nat. Med. 2006, 12:1410-1416.
-
(2006)
Nat. Med.
, vol.12
, pp. 1410-1416
-
-
Sato, K.1
Suematsu, A.2
Nakashima, T.3
Takemoto-Kimura, S.4
Aoki, K.5
Morishita, Y.6
Asahara, H.7
Ohya, K.8
Yamaguchi, A.9
Takai, T.10
Kodama, T.11
Chatila, T.A.12
Bito, H.13
Takayanagi, H.14
-
4
-
-
33750597150
-
PLCγ2 regulates osteoclastogenesis via its interaction with ITAM proteins and GAB2
-
Mao D., Epple H., Uthgenannt B., Novack D.V., Faccio R. PLCγ2 regulates osteoclastogenesis via its interaction with ITAM proteins and GAB2. J. Clin. Invest. 2006, 116:2869-2879.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 2869-2879
-
-
Mao, D.1
Epple, H.2
Uthgenannt, B.3
Novack, D.V.4
Faccio, R.5
-
6
-
-
39749180445
-
Tyrosine kinase Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals
-
Shinohara M., Koga T., Okamoto K., Sakaguchi S., Arai K., Yasuda H., Takai T., Kodama T., Morio T., Geha R.S., Kitamura D., Kurosaki T., Ellmeier W., Takayanagi H. Tyrosine kinase Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals. Cell 2008, 132:794-806.
-
(2008)
Cell
, vol.132
, pp. 794-806
-
-
Shinohara, M.1
Koga, T.2
Okamoto, K.3
Sakaguchi, S.4
Arai, K.5
Yasuda, H.6
Takai, T.7
Kodama, T.8
Morio, T.9
Geha, R.S.10
Kitamura, D.11
Kurosaki, T.12
Ellmeier, W.13
Takayanagi, H.14
-
8
-
-
0037155588
-
Signal transduction. Hot and cold TRP ion channels
-
Clapham D.E. Signal transduction. Hot and cold TRP ion channels. Science 2002, 295:2228-2229.
-
(2002)
Science
, vol.295
, pp. 2228-2229
-
-
Clapham, D.E.1
-
9
-
-
0347504835
-
TRP channels as cellular sensors
-
Clapham D.E. TRP channels as cellular sensors. Nature 2003, 426:517-524.
-
(2003)
Nature
, vol.426
, pp. 517-524
-
-
Clapham, D.E.1
-
10
-
-
0033119629
-
A capsaicin-receptor homologue with a high threshod for noxious heat
-
Cateria M.J., Rosen T.A., Tominaga M., Brake A.J., Julius D. A capsaicin-receptor homologue with a high threshod for noxious heat. Nature 1999, 396:436-441.
-
(1999)
Nature
, vol.396
, pp. 436-441
-
-
Cateria, M.J.1
Rosen, T.A.2
Tominaga, M.3
Brake, A.J.4
Julius, D.5
-
11
-
-
0033162068
-
Translocation of a calcium-permeable cation channel induced by insulin-like growth factor I
-
Kanzaki M., Zhang Y.Q., Mashima H., Li L., Shibata H., Kojima I. Translocation of a calcium-permeable cation channel induced by insulin-like growth factor I. Nat. Cell Biol. 1999, 1:165-170.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 165-170
-
-
Kanzaki, M.1
Zhang, Y.Q.2
Mashima, H.3
Li, L.4
Shibata, H.5
Kojima, I.6
-
12
-
-
1242296878
-
Immunoreactive TRPV-2 (VRL-1), a capsaicin receptor homolog, in the spinal cord of the rat
-
Lewinter R.D., Skinner K., Julius D., Basbaum A.I. Immunoreactive TRPV-2 (VRL-1), a capsaicin receptor homolog, in the spinal cord of the rat. J. Comp. Neurol. 2004, 470:400-408.
-
(2004)
J. Comp. Neurol.
, vol.470
, pp. 400-408
-
-
Lewinter, R.D.1
Skinner, K.2
Julius, D.3
Basbaum, A.I.4
-
13
-
-
0242266967
-
TRPV2 is a component of osmotically sensitive cation channels in murine aortic myocytes
-
Muraki K., Iwata Y., Katanosaka Y., Ito T., Ohya S., Shigekawa M., Imaizemi Y. TRPV2 is a component of osmotically sensitive cation channels in murine aortic myocytes. Circ. Res. 2003, 93:829-838.
-
(2003)
Circ. Res.
, vol.93
, pp. 829-838
-
-
Muraki, K.1
Iwata, Y.2
Katanosaka, Y.3
Ito, T.4
Ohya, S.5
Shigekawa, M.6
Imaizemi, Y.7
-
15
-
-
3242784060
-
A TRAPV2-PKA signaling module for transduction of physical stimuli in mast cells
-
Stokes A.J., Shimoda L.M.N., Koblan-Huberson M., Adra C.N., Turner H. A TRAPV2-PKA signaling module for transduction of physical stimuli in mast cells. J. Exp. Med. 2004, 200:137-147.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 137-147
-
-
Stokes, A.J.1
Shimoda, L.M.N.2
Koblan-Huberson, M.3
Adra, C.N.4
Turner, H.5
-
16
-
-
33846807748
-
Transient receptor potential cation channels in disease
-
Nilius B., Owsianik G., Voets T., Peters J.A. Transient receptor potential cation channels in disease. Physiol. Rev. 2007, 87:165-217.
-
(2007)
Physiol. Rev.
, vol.87
, pp. 165-217
-
-
Nilius, B.1
Owsianik, G.2
Voets, T.3
Peters, J.A.4
-
17
-
-
70349100754
-
2+-NFATc1 signaling is an essential axis of osteoclast differentiation
-
2+-NFATc1 signaling is an essential axis of osteoclast differentiation. Immunol. Rev. 2009, 231:241-256.
-
(2009)
Immunol. Rev.
, vol.231
, pp. 241-256
-
-
Negishi-Koga, T.1
Takayanagi, H.2
-
18
-
-
77951213242
-
2+ oscillation essential for osteoclastogenesis
-
2+ oscillation essential for osteoclastogenesis. J. Biol. Chem. 2010, 285:6913-6921.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 6913-6921
-
-
Kim, M.S.1
Yang, Y.M.2
Son, A.3
Tian, Y.S.4
Lee, S.L.5
Kang, S.W.6
Muallem, S.7
Shin, D.M.8
-
19
-
-
0034759617
-
2+-permeable channel GRC
-
2+-permeable channel GRC. J. Cell Sci. 2001, 114:3599-3606.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 3599-3606
-
-
Boels, K.1
Glassmeier, G.2
Herrmann, D.3
Riedel, I.B.4
Hampe, W.5
Kojima, I.6
Schwarz, J.R.7
Schaller, C.8
-
21
-
-
33646495512
-
PI3-kinase promotes TRPV2 activity independently of channel translocation to the plasma membrane
-
Penna A., Juvin V., Chemin J., Compan V., Monet M., Rassendren F.A. PI3-kinase promotes TRPV2 activity independently of channel translocation to the plasma membrane. Cell calcium 2006, 39:493-507.
-
(2006)
Cell calcium
, vol.39
, pp. 493-507
-
-
Penna, A.1
Juvin, V.2
Chemin, J.3
Compan, V.4
Monet, M.5
Rassendren, F.A.6
-
22
-
-
21744446898
-
Formation of a physiological complex between TRPV2 and RGA proteins promotes cell surface expression of TRPV2
-
Stokes A.J., Wakano C., Del Carmen K.A., Koblan-Huberson M., Turner H. Formation of a physiological complex between TRPV2 and RGA proteins promotes cell surface expression of TRPV2. J. Cell Biochem. 2005, 94:669-683.
-
(2005)
J. Cell Biochem.
, vol.94
, pp. 669-683
-
-
Stokes, A.J.1
Wakano, C.2
Del Carmen, K.A.3
Koblan-Huberson, M.4
Turner, H.5
-
23
-
-
11144354330
-
Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis
-
Koga T., Inui M., Inoue K., Kim S., Suemaru A., Kobayashi E., Iwata T., Ohnishi H., Matozaki T., Kodama T., Taniguchi T., Takayanagi H., Takai T. Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis. Nature 2004, 428:758-763.
-
(2004)
Nature
, vol.428
, pp. 758-763
-
-
Koga, T.1
Inui, M.2
Inoue, K.3
Kim, S.4
Suemaru, A.5
Kobayashi, E.6
Iwata, T.7
Ohnishi, H.8
Matozaki, T.9
Kodama, T.10
Taniguchi, T.11
Takayanagi, H.12
Takai, T.13
-
24
-
-
11144355389
-
The immunomodulatory adapter proteins DAP12 and Fc receptor γ-chain (FcRγ) regulate development of functional osteoclasts through the Syk tyrosine kinase
-
Mocsai A., Humphrey M.B., Van Ziffle J.A.G., Hu Y., Burghardt A., Spusta S.C., Majumdar S., Lanier L.L., Lowell C.A., Nakamura M.C. The immunomodulatory adapter proteins DAP12 and Fc receptor γ-chain (FcRγ) regulate development of functional osteoclasts through the Syk tyrosine kinase. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:6153-6158.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 6153-6158
-
-
Mocsai, A.1
Humphrey, M.B.2
Van Ziffle, J.A.G.3
Hu, Y.4
Burghardt, A.5
Spusta, S.C.6
Majumdar, S.7
Lanier, L.L.8
Lowell, C.A.9
Nakamura, M.C.10
-
25
-
-
0037314230
-
Osteopetrosis and thalamic hypomyelinosis with synaptic degeration in DAP12-deficient mice
-
Kaifu T., Nakahara J., Inui M., Mishima K., Momiyama T., Kaji M., Sugahara A., Koito H., Ujike-Asai A., Nakamura A., Kanazawa K., Tan-Takeuchi, Iwasaki K., Yokoyama W.M., Kudo A., Fujiwara M., Asou H., Takai T. Osteopetrosis and thalamic hypomyelinosis with synaptic degeration in DAP12-deficient mice. J. Clin. Invest. 2003, 111:323-332.
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 323-332
-
-
Kaifu, T.1
Nakahara, J.2
Inui, M.3
Mishima, K.4
Momiyama, T.5
Kaji, M.6
Sugahara, A.7
Koito, H.8
Ujike-Asai, A.9
Nakamura, A.10
Kanazawa, K.11
Tan-Takeuchi Iwasaki, K.12
Yokoyama, W.M.13
Kudo, A.14
Fujiwara, M.15
Asou, H.16
Takai, T.17
-
26
-
-
45549099188
-
The Tec family tyrosine kinase Btk regulates RANKL-induced osteoclast maturation
-
Lee S.H., Kim T., Jeong D., Kim N., Choi Y. The Tec family tyrosine kinase Btk regulates RANKL-induced osteoclast maturation. J. Biol. Chem. 2008, 283:11526-11534.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 11526-11534
-
-
Lee, S.H.1
Kim, T.2
Jeong, D.3
Kim, N.4
Choi, Y.5
-
27
-
-
33947240223
-
Syk, c-Src, the αvβ3 integrin, and ITAM immunoreceptors, in coccert, regulate osteoclastic bone resorption
-
Zou W., Kitaura H., Reeve J., Long F., Tybulewicz V.L.J., Shattil S.J., Ginsberg M.H., Patrick Ross F., Teitelbaum S.L. Syk, c-Src, the αvβ3 integrin, and ITAM immunoreceptors, in coccert, regulate osteoclastic bone resorption. J. Cell Biol. 2007, 176:877-888.
-
(2007)
J. Cell Biol.
, vol.176
, pp. 877-888
-
-
Zou, W.1
Kitaura, H.2
Reeve, J.3
Long, F.4
Tybulewicz, V.L.J.5
Shattil, S.J.6
Ginsberg, M.H.7
Patrick Ross, F.8
Teitelbaum, S.L.9
-
28
-
-
2542637189
-
The role of Tec family kinases in myeloid cells
-
Schmidt U., Boucheron N., Unger B., Ellmeier W. The role of Tec family kinases in myeloid cells. Int. Arch. Allergy Immunol. 2004, 134:65-78.
-
(2004)
Int. Arch. Allergy Immunol.
, vol.134
, pp. 65-78
-
-
Schmidt, U.1
Boucheron, N.2
Unger, B.3
Ellmeier, W.4
-
29
-
-
0038125598
-
Calcium signaling; dynamics, homeostasis and remodeling
-
Berridge M.J., Bootman M.D., Roderick H.L. Calcium signaling; dynamics, homeostasis and remodeling. Nat. Rev. Mol. Cell Biol. 2003, 4:517-525.
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 517-525
-
-
Berridge, M.J.1
Bootman, M.D.2
Roderick, H.L.3
-
30
-
-
50049122815
-
TRPV4-mediated calcium influx regulates terminal differentiation of osteoclasts
-
Masuyama R., Vriens J., Voets T., Karashima Y., Owsianik G., Vennekens R., Lieben L., Torrekens S., Moermans K., Bosch A.V., Bouillon R., Nilius B. TRPV4-mediated calcium influx regulates terminal differentiation of osteoclasts. Cell Metab. 2008, 8:257-265.
-
(2008)
Cell Metab.
, vol.8
, pp. 257-265
-
-
Masuyama, R.1
Vriens, J.2
Voets, T.3
Karashima, Y.4
Owsianik, G.5
Vennekens, R.6
Lieben, L.7
Torrekens, S.8
Moermans, K.9
Bosch, A.V.10
Bouillon, R.11
Nilius, B.12
-
31
-
-
0032580202
-
Calcium oscillation increase the efficiency and specificity of gene expression
-
Dolmetsch R.E., Xu J., Lewis R.S. Calcium oscillation increase the efficiency and specificity of gene expression. Nature 1998, 392:933-936.
-
(1998)
Nature
, vol.392
, pp. 933-936
-
-
Dolmetsch, R.E.1
Xu, J.2
Lewis, R.S.3
-
34
-
-
0037134461
-
Capacitative calcium entry contributes to nuclear factor of activated T-cells nuclear translocation and hypertrophy in cardiomyocytes
-
Hunton D.L., Lucchesi P.A., Pang Y., Cheng X., Dell'talia L.J., Marchase R.B. Capacitative calcium entry contributes to nuclear factor of activated T-cells nuclear translocation and hypertrophy in cardiomyocytes. J. Biol. Chem. 2002, 277:14266-14273.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 14266-14273
-
-
Hunton, D.L.1
Lucchesi, P.A.2
Pang, Y.3
Cheng, X.4
Dell'talia, L.J.5
Marchase, R.B.6
-
35
-
-
0027500251
-
Inositol 1,4,5-triphosphate receptor expression in cardiac myocytes
-
Moschella M.C., Marks A.R. Inositol 1,4,5-triphosphate receptor expression in cardiac myocytes. J. Cell Biol. 1993, 120:1137-1146.
-
(1993)
J. Cell Biol.
, vol.120
, pp. 1137-1146
-
-
Moschella, M.C.1
Marks, A.R.2
|