-
3
-
-
0033611472
-
A trial of Etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate
-
Weinblatt ME, Kremer JM, Bankhurst AD, Bulpitt KJ, Fleischmann RM, Fox RI et al (1999) A trial of Etanercept, a recombinant tumor necrosis factor receptor:Fc fusion protein, in patients with rheumatoid arthritis receiving methotrexate. NEJM 340:253-259
-
(1999)
NEJM
, vol.340
, pp. 253-259
-
-
Weinblatt, M.E.1
Kremer, J.M.2
Bankhurst, A.D.3
Bulpitt, K.J.4
Fleischmann, R.M.5
Fox, R.I.6
-
4
-
-
0027415109
-
Lymphotoxin beta, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface
-
Browning JL, Ngam-ek A, Lawton P, DeMarinis J, Tizard R, Chow EP et al (1993) Lymphotoxin beta, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface. Cell 26:847-856
-
(1993)
Cell
, vol.26
, pp. 847-856
-
-
Browning, J.L.1
Ngam-Ek, A.2
Lawton, P.3
Demarinis, J.4
Tizard, R.5
Chow, E.P.6
-
5
-
-
0037083571
-
Innate direct anticancer effector function of human immature dendritic cells. II. Role of TNF, Lymphotoxin-[alpha]1[beta]2, fas ligand, and TNF-related apoptosis-inducing ligand
-
Lu G, Janjic BM, Janjic J, Whiteside TL, Storkus WJ, Vujanovic NL (2002) Innate direct anticancer effector function of human immature dendritic cells. II. Role of TNF, Lymphotoxin-[alpha]1[beta]2, fas ligand, and TNF-related apoptosis-inducing ligand. J Immunol 168:1831-1839
-
(2002)
J Immunol
, vol.168
, pp. 1831-1839
-
-
Lu, G.1
Janjic, B.M.2
Janjic, J.3
Whiteside, T.L.4
Storkus, W.J.5
Vujanovic, N.L.6
-
6
-
-
0037218879
-
Expression of lymphotoxin-beta (LT-Beta) in chronic inflammatory conditions
-
Agyekum S, Church A, Sohail M, Krausz T, Van Noorden S, Polak J et al (2003) Expression of lymphotoxin-beta (LT-Beta) in chronic inflammatory conditions. J Pathol 199:115-21
-
(2003)
J Pathol
, vol.199
, pp. 115-21
-
-
Agyekum, S.1
Church, A.2
Sohail, M.3
Krausz, T.4
Van Noorden, S.5
Polak, J.6
-
7
-
-
0034092320
-
Autocrine regulation of collagenase 3 (Matrix Metallo Proteinase 13) during osteoarthritis
-
Shlopov BV, Gumanovskaya ML, Hasty KA (2000) Autocrine regulation of collagenase 3 (Matrix Metallo Proteinase 13) during osteoarthritis. Arthritis Rheum 43:195-205
-
(2000)
Arthritis Rheum
, vol.43
, pp. 195-205
-
-
Shlopov, B.V.1
Gumanovskaya, M.L.2
Hasty, K.A.3
-
8
-
-
0029778869
-
Lymphotoxin beta receptor triggering induces activation of the nuclear factor kappaB transcription factor in some cell types
-
Mackay F, Majeau GR, Hochman PS, Browning JL. (1996) Lymphotoxin beta receptor triggering induces activation of the nuclear factor kappaB transcription factor in some cell types. J Biol Chem 271:24934-8
-
(1996)
J Biol Chem
, vol.271
, pp. 24934-8
-
-
MacKay, F.1
Majeau, G.R.2
Hochman, P.S.3
Browning, J.L.4
-
9
-
-
19244364722
-
Genetic variability in the tumor necrosis factor-lymphotoxin region influences susceptibility to rheumatoid arthritis
-
3
-
Mulcahy B, Waldron-Lynch F, McDermott MF, Adams C, Amos CI, Zhu DK, Ward RH, Clegg DO, Shanahan F, Molloy MG, O'Gara F (1996) Genetic variability in the tumor necrosis factor-lymphotoxin region influences susceptibility to rheumatoid arthritis. Am J Hum Genet 59(3):676-683
-
(1996)
Am J Hum Genet
, vol.59
, pp. 676-683
-
-
Mulcahy, B.1
Waldron-Lynch, F.2
McDermott, M.F.3
Adams, C.4
Amos, C.I.5
Zhu, D.K.6
Ward, R.H.7
Clegg, D.O.8
Shanahan, F.9
Molloy, M.G.10
O'Gara, F.11
-
11
-
-
0037195132
-
Despite ubiquitous autoantigen expression arthrogenic autoantibody response initiates in the local lymph node
-
Mandik-Nayak L, Wipke BT, Shih FF, Unanue ER, Allen PM (2002) Despite ubiquitous autoantigen expression arthrogenic autoantibody response initiates in the local lymph node. PNAS 99:14368-14373
-
(2002)
PNAS
, vol.99
, pp. 14368-14373
-
-
Mandik-Nayak, L.1
Wipke, B.T.2
Shih, F.F.3
Unanue, E.R.4
Allen, P.M.5
-
12
-
-
0035879123
-
Lymphoid neogenesis in rheumatoid synovitis
-
Takemura S, Braun A, Crowson C, Kurtin PJ, Cofield RH, O'Fallon WM et al (2001) Lymphoid neogenesis in rheumatoid synovitis. J Immunol 167:1072-1080
-
(2001)
J Immunol
, vol.167
, pp. 1072-1080
-
-
Takemura, S.1
Braun, A.2
Crowson, C.3
Kurtin, P.J.4
Cofield, R.H.5
O'Fallon, W.M.6
-
13
-
-
0032127288
-
Lymph node genesis is induced by signaling through the lymphotoxin beta receptor
-
Rennert PD, James D, Mackay F, Browning JL, Hochman PS (1998) Lymph node genesis is induced by signaling through the lymphotoxin beta receptor. Immunity 9:71-79
-
(1998)
Immunity
, vol.9
, pp. 71-79
-
-
Rennert, P.D.1
James, D.2
MacKay, F.3
Browning, J.L.4
Hochman, P.S.5
-
14
-
-
84988231240
-
The health assessment questionnaire 1992: Status and review
-
Ramey DR, Raynaud JP, Fries JF (1992) The health assessment questionnaire 1992: status and review. Arthritis Care Res 5:119-129
-
(1992)
Arthritis Care Res
, vol.5
, pp. 119-129
-
-
Ramey, D.R.1
Raynaud, J.P.2
Fries, J.F.3
-
15
-
-
0027413819
-
Sensitivity to change of rheumatoid arthritis clinical trial outcome measures
-
Anderson JJ, Chernoff MC (1993) Sensitivity to change of rheumatoid arthritis clinical trial outcome measures. J Rheumatol 20:535-537
-
(1993)
J Rheumatol
, vol.20
, pp. 535-537
-
-
Anderson, J.J.1
Chernoff, M.C.2
-
16
-
-
0021339874
-
Immunohistologic characterization of synovial membrane lymphocytes in rheumatoid arthritis
-
Young CL, Adamson TC, Vaughan JH, Fox RI (1984) Immunohistologic characterization of synovial membrane lymphocytes in rheumatoid arthritis. Arthritis Rheum 27:32-39
-
(1984)
Arthritis Rheum
, vol.27
, pp. 32-39
-
-
Young, C.L.1
Adamson, T.C.2
Vaughan, J.H.3
Fox, R.I.4
-
17
-
-
0033913994
-
Hitopathology and molecular pathology of synovial B-lymphocytes in rheumatoid arthritis
-
Krenn V, Souto-Carneiro MM, Kim HJ, Berek C, Starostik P, Konig A et al (2000) Hitopathology and molecular pathology of synovial B-lymphocytes in rheumatoid arthritis. Histol Histopathol 15:791-798
-
(2000)
Histol Histopathol
, vol.15
, pp. 791-798
-
-
Krenn, V.1
Souto-Carneiro, M.M.2
Kim, H.J.3
Berek, C.4
Starostik, P.5
Konig, A.6
-
18
-
-
0032944731
-
Synovitis in rheumatoid arthritis: Scoring of characteristic histopathological features
-
Koizumi F, Matsuno H, Wakaki K, Ishii Y, Kurashige Y, Nakamura H (1999) Synovitis in rheumatoid arthritis: scoring of characteristic histopathological features. Pathol Int 49:298-304
-
(1999)
Pathol Int
, vol.49
, pp. 298-304
-
-
Koizumi, F.1
Matsuno, H.2
Wakaki, K.3
Ishii, Y.4
Kurashige, Y.5
Nakamura, H.6
-
19
-
-
0030921694
-
Design and testing of beta-actin primers for RT-PCR that do not co-amplify pseudogenes
-
Raff T, Van der Giet M, Endemann D, Wiederholt T, Paul M (1997) Design and testing of beta-actin primers for RT-PCR that do not co-amplify pseudogenes. Biotechniques 23:456-460
-
(1997)
Biotechniques
, vol.23
, pp. 456-460
-
-
Raff, T.1
Van Der Giet, M.2
Endemann, D.3
Wiederholt, T.4
Paul, M.5
-
20
-
-
3142724043
-
Lymphotoxin beta-mediated stimulation of synoviocytes in rheumatoid arthritis
-
Braun A, Takemura S, Vallejo AN, Goronzy JJ, Weyand CM (2004) Lymphotoxin beta-mediated stimulation of synoviocytes in rheumatoid arthritis. Arthritis Rheum 50:2140-2150
-
(2004)
Arthritis Rheum
, vol.50
, pp. 2140-2150
-
-
Braun, A.1
Takemura, S.2
Vallejo, A.N.3
Goronzy, J.J.4
Weyand, C.M.5
-
21
-
-
0034691531
-
A Chemokine-driven positive feedback loop organizes lymphoid follicles
-
Ansel KM, Ngo VN, Hyman PL, Luther SA, Forster R, Sedgwick JD et al (2000) A Chemokine-driven positive feedback loop organizes lymphoid follicles. Nature 406:309-314
-
(2000)
Nature
, vol.406
, pp. 309-314
-
-
Ansel, K.M.1
Ngo, V.N.2
Hyman, P.L.3
Luther, S.A.4
Forster, R.5
Sedgwick, J.D.6
-
22
-
-
0036839571
-
Is NFkB a useful therapeutic target in rheumatoid arthritis
-
Suppl 2
-
Feldmann M, Andreakos E, Smith C, Bondeson J, Yoshimura S, Kiriakidis S et al (2002) Is NFkB a useful therapeutic target in rheumatoid arthritis. Ann Rheum Dis 61(Suppl 2):13-18
-
(2002)
Ann Rheum Dis
, vol.61
, pp. 13-18
-
-
Feldmann, M.1
Andreakos, E.2
Smith, C.3
Bondeson, J.4
Yoshimura, S.5
Kiriakidis, S.6
-
23
-
-
0029923540
-
Functional analysis of the lymphotoxin-B promoter
-
Kuprash DV, Osipovich OA, Pokholok DK, Alimzhanov MB, Biragyn A, Turetskaya RL et al (1996) Functional analysis of the lymphotoxin-B promoter. J Immunol 156:2465-2472
-
(1996)
J Immunol
, vol.156
, pp. 2465-2472
-
-
Kuprash, D.V.1
Osipovich, O.A.2
Pokholok, D.K.3
Alimzhanov, M.B.4
Biragyn, A.5
Turetskaya, R.L.6
-
24
-
-
0035677859
-
Regulation of lymphotoxin-beta by tumor necrosis factor, phorbol myristate acetate, and ionomycin in Jurkat T cells
-
Voon DC, Subrata LS, Abraham LJ (2001) Regulation of lymphotoxin-beta by tumor necrosis factor, phorbol myristate acetate, and ionomycin in Jurkat T cells. J Interferon Cytokine Res 21:921-930
-
(2001)
J Interferon Cytokine Res
, vol.21
, pp. 921-930
-
-
Voon, D.C.1
Subrata, L.S.2
Abraham, L.J.3
-
25
-
-
0025332578
-
Effects of tumor necrosis factor alpha and beta on resorption of human articular cartilage and production of plasminogen activator by human articular chondrocytes
-
Campbell IK, Piccoli DS, Roberts MJ, Muirden KD, Hamilton JA (1990) Effects of tumor necrosis factor alpha and beta on resorption of human articular cartilage and production of plasminogen activator by human articular chondrocytes. Arthritis Rheum 33:542-552
-
(1990)
Arthritis Rheum
, vol.33
, pp. 542-552
-
-
Campbell, I.K.1
Piccoli, D.S.2
Roberts, M.J.3
Muirden, K.D.4
Hamilton, J.A.5
-
26
-
-
0023095815
-
Tumour necrosis factor alpha and beta induce osteoblastic cells to stimulate osteoclast bone resorption
-
Thomson BM, Mundy GR, Chambers TJ (1987) Tumour necrosis factor alpha and beta induce osteoblastic cells to stimulate osteoclast bone resorption. J Immunol 138:775-779
-
(1987)
J Immunol
, vol.138
, pp. 775-779
-
-
Thomson, B.M.1
Mundy, G.R.2
Chambers, T.J.3
-
27
-
-
0024263751
-
Tumour necrosis factor-beta modulates human neutrophil-mediated cartilage damage
-
Kowanko IC, Bates EJ, Ferrante A (1988) Tumour necrosis factor-beta modulates human neutrophil-mediated cartilage damage. Scand J Immunol 28:591-598
-
(1988)
Scand J Immunol
, vol.28
, pp. 591-598
-
-
Kowanko, I.C.1
Bates, E.J.2
Ferrante, A.3
-
28
-
-
0036720395
-
Cyclosporin a blocks the expression of lymphotoxin alpha, but not lymphotoxin beta in human peripheral blood mononuclear cells
-
Kuprash DV, Boitchenko VE, Yarovinsky FO, Rice NR, Nordheim A, Ruhlmann A et al (2002) Cyclosporin A blocks the expression of lymphotoxin alpha, but not lymphotoxin beta in human peripheral blood mononuclear cells. Blood 100:1721-1727
-
(2002)
Blood
, vol.100
, pp. 1721-1727
-
-
Kuprash, D.V.1
Boitchenko, V.E.2
Yarovinsky, F.O.3
Rice, N.R.4
Nordheim, A.5
Ruhlmann, A.6
-
29
-
-
0033818479
-
The role of tumour necrosis factor and lymphotoxin in lymphoid organ development
-
Ettinger R (2000) The role of tumour necrosis factor and lymphotoxin in lymphoid organ development. Curr Top Microbiol Immunol 251:203-210
-
(2000)
Curr Top Microbiol Immunol
, vol.251
, pp. 203-210
-
-
Ettinger, R.1
-
30
-
-
0035889229
-
NK-kB-inducing kinase is dispensible for activation of NF-kB in inflammatory settings but essential for lymphotoxin B receptor activation of NFkB in primary human fibroblasts
-
Smith C, Andreakos E, Crawley JB, Brennan FM, Feldmann M, Foxwell B (2001) NK-kB-inducing kinase is dispensible for activation of NF-kB in inflammatory settings but essential for lymphotoxin B receptor activation of NFkB in primary human fibroblasts. J Immunol 167:5895-5903
-
(2001)
J Immunol
, vol.167
, pp. 5895-5903
-
-
Smith, C.1
Andreakos, E.2
Crawley, J.B.3
Brennan, F.M.4
Feldmann, M.5
Foxwell, B.6
-
31
-
-
0034253390
-
Functional effects of TNF and lymphotoxin alpha1beta2 on FDC-like cells
-
Husson H, Lugli SM, Ghia P, Cardosso A, Roth A, Brohmi K et al (2000) Functional effects of TNF and lymphotoxin alpha1beta2 on FDC-like cells. Cell Immunol 203:134-143
-
(2000)
Cell Immunol
, vol.203
, pp. 134-143
-
-
Husson, H.1
Lugli, S.M.2
Ghia, P.3
Cardosso, A.4
Roth, A.5
Brohmi, K.6
-
32
-
-
0025274640
-
Cytokine and cytokine inhibitors or antagonists in rheumatoid arthritis
-
Arend WP, Dayer J-M (1990) Cytokine and cytokine inhibitors or antagonists in rheumatoid arthritis. Arthritis Rheum 33:305-315
-
(1990)
Arthritis Rheum
, vol.33
, pp. 305-315
-
-
Arend, W.P.1
Dayer, J.-M.2
-
33
-
-
0025789094
-
Enhancers and transcription factors controlling inducibility of the tumor necrosis factor-alpha promoter in primary macrophages
-
Drouet C, Shahhov AN, Jongeneel CV (1991) Enhancers and transcription factors controlling inducibility of the tumor necrosis factor-alpha promoter in primary macrophages. J Immunol 147:1694-1700
-
(1991)
J Immunol
, vol.147
, pp. 1694-1700
-
-
Drouet, C.1
Shahhov, A.N.2
Jongeneel, C.V.3
-
34
-
-
47249085362
-
What lessons can we learn from the study of pain pathways in rheumatic disease?
-
Kidd B (2004) What lessons can we learn from the study of pain pathways in rheumatic disease? J RCPE 34:66-67
-
(2004)
J RCPE
, vol.34
, pp. 66-67
-
-
Kidd, B.1
-
35
-
-
0035806277
-
Reversal of spontaneous autoimmune insulitis in nonobese diabetic mice by soluble lymphotoxin receptor
-
Wu Q, Saloman B, Chen M, Wang Y, Hoffman LM, Bluestone JA et al (2001) Reversal of spontaneous autoimmune insulitis in nonobese diabetic mice by soluble lymphotoxin receptor. J Exp Med 193:1327-1332
-
(2001)
J Exp Med
, vol.193
, pp. 1327-1332
-
-
Wu, Q.1
Saloman, B.2
Chen, M.3
Wang, Y.4
Hoffman, L.M.5
Bluestone, J.A.6
-
36
-
-
0031760741
-
Both the lymphotoxin and tumour necrosis pathways are involved in experimental murine models of colitis
-
Mackay F, Browning JL, Lawton P, Shah SA, Comiskey M, Bhan AK et al (1998) Both the lymphotoxin and tumour necrosis pathways are involved in experimental murine models of colitis. Gastroenterology 115:1464-1475
-
(1998)
Gastroenterology
, vol.115
, pp. 1464-1475
-
-
MacKay, F.1
Browning, J.L.2
Lawton, P.3
Shah, S.A.4
Comiskey, M.5
Bhan, A.K.6
-
37
-
-
85047686597
-
Blockage of LIGHT / Ltbeta and CD 40 signalling induces allospecific T cell anergy, preventing graft-versus-host disease
-
Tamada K, Tamura H, Flies D, Fu YX, Celis E, Pease LR et al (2002) Blockage of LIGHT / Ltbeta and CD 40 signalling induces allospecific T cell anergy, preventing graft-versus-host disease. J Clin Invest 109:549-557
-
(2002)
J Clin Invest
, vol.109
, pp. 549-557
-
-
Tamada, K.1
Tamura, H.2
Flies, D.3
Fu, Y.X.4
Celis, E.5
Pease, L.R.6
|