-
1
-
-
84893785374
-
-
Available from URL: Accessed 20 August 2013.
-
Available from URL: http://www.cdc.gov/obesity/data/adult.html. Accessed 20 August 2013.
-
-
-
-
2
-
-
2942554887
-
Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002
-
Hedley AA, Ogden CL, Johnson CL, Carroll MD, Curtin LR, Flegal KM. Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002. JAMA 2004; 291: 2847-2850.
-
(2004)
JAMA
, vol.291
, pp. 2847-2850
-
-
Hedley, A.A.1
Ogden, C.L.2
Johnson, C.L.3
Carroll, M.D.4
Curtin, L.R.5
Flegal, K.M.6
-
3
-
-
35948958973
-
Body mass index predicts aldosterone production in normotensive adults on a high-salt diet
-
Bentley-Lewis R, Adler GK, Perlstein T et al. Body mass index predicts aldosterone production in normotensive adults on a high-salt diet. J Clin Endocrinol Metab 2007; 92: 4472-4475.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 4472-4475
-
-
Bentley-Lewis, R.1
Adler, G.K.2
Perlstein, T.3
-
4
-
-
47549088476
-
Body mass index predicts plasma aldosterone concentrations in overweight-obese primary hypertensive patients
-
Rossi GP, Belfiore A, Bernini G et al. Body mass index predicts plasma aldosterone concentrations in overweight-obese primary hypertensive patients. J Clin Endocrinol Metab 2008; 93: 2566-2571.
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 2566-2571
-
-
Rossi, G.P.1
Belfiore, A.2
Bernini, G.3
-
6
-
-
84860729652
-
Role of mineralocorticoid receptor in insulin resistance
-
Garg R, Adler GK. Role of mineralocorticoid receptor in insulin resistance. Curr Opin Endocrinol Diabetes Obes 2012; 19: 168-175.
-
(2012)
Curr Opin Endocrinol Diabetes Obes
, vol.19
, pp. 168-175
-
-
Garg, R.1
Adler, G.K.2
-
7
-
-
84873027749
-
Mineralocorticoid receptor-mediated vascular insulin resistance: an early contributor to diabetes-related vascular disease?
-
Bender SB, McGraw AP, Jaffe IZ, Sowers JR. Mineralocorticoid receptor-mediated vascular insulin resistance: an early contributor to diabetes-related vascular disease? Diabetes 2013; 62: 313-319.
-
(2013)
Diabetes
, vol.62
, pp. 313-319
-
-
Bender, S.B.1
McGraw, A.P.2
Jaffe, I.Z.3
Sowers, J.R.4
-
8
-
-
33646366660
-
Spironolactone prevents diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats
-
Han SY, Kim CH, Kim HS et al. Spironolactone prevents diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats. J Am Soc Nephrol 2006; 17: 1362-1372.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 1362-1372
-
-
Han, S.Y.1
Kim, C.H.2
Kim, H.S.3
-
9
-
-
63849107748
-
Aldosterone inhibits insulin-induced glucose uptake by degradation of insulin receptor substrate (IRS) 1 and IRS2 via a reactive oxygen species-mediated pathway in 3 T3-L1 adipocytes
-
Wada T, Ohshima S, Fujisawa E, Koya D, Tsuneki H, Sasaoka T. Aldosterone inhibits insulin-induced glucose uptake by degradation of insulin receptor substrate (IRS) 1 and IRS2 via a reactive oxygen species-mediated pathway in 3 T3-L1 adipocytes. Endocrinology 2009; 150: 1662-1669.
-
(2009)
Endocrinology
, vol.150
, pp. 1662-1669
-
-
Wada, T.1
Ohshima, S.2
Fujisawa, E.3
Koya, D.4
Tsuneki, H.5
Sasaoka, T.6
-
10
-
-
70449718904
-
Blockade of mineralocorticoid receptor reverses adipocyte dysfunction and insulin resistance in obese mice
-
Hirata A, Maeda N, Hiuge A et al. Blockade of mineralocorticoid receptor reverses adipocyte dysfunction and insulin resistance in obese mice. Cardiovasc Res 2009; 84: 164-172.
-
(2009)
Cardiovasc Res
, vol.84
, pp. 164-172
-
-
Hirata, A.1
Maeda, N.2
Hiuge, A.3
-
11
-
-
44049097881
-
Mineralocorticoid receptor blockade reverses obesity-related changes in expression of adiponectin, peroxisome proliferator-activated receptor-gamma, and proinflammatory adipokines
-
Guo C, Ricchiuti V, Lian BQ et al. Mineralocorticoid receptor blockade reverses obesity-related changes in expression of adiponectin, peroxisome proliferator-activated receptor-gamma, and proinflammatory adipokines. Circulation 2008; 117: 2253-2261.
-
(2008)
Circulation
, vol.117
, pp. 2253-2261
-
-
Guo, C.1
Ricchiuti, V.2
Lian, B.Q.3
-
12
-
-
13444283520
-
Mineralocorticoid receptor inhibition ameliorates the transition to myocardial failure and decreases oxidative stress and inflammation in mice with chronic pressure overload
-
Kuster GM, Kotlyar E, Rude MK et al. Mineralocorticoid receptor inhibition ameliorates the transition to myocardial failure and decreases oxidative stress and inflammation in mice with chronic pressure overload. Circulation 2005; 111: 420-427.
-
(2005)
Circulation
, vol.111
, pp. 420-427
-
-
Kuster, G.M.1
Kotlyar, E.2
Rude, M.K.3
-
13
-
-
33751236177
-
Mineralocorticoid receptor antagonist reduces renal injury in rodent models of types 1 and 2 diabetes mellitus
-
Guo C, Martinez-Vasquez D, Mendez GP et al. Mineralocorticoid receptor antagonist reduces renal injury in rodent models of types 1 and 2 diabetes mellitus. Endocrinology 2006; 147: 5363-5373.
-
(2006)
Endocrinology
, vol.147
, pp. 5363-5373
-
-
Guo, C.1
Martinez-Vasquez, D.2
Mendez, G.P.3
-
14
-
-
77953165944
-
Spironolactone improves glucose and lipid metabolism by ameliorating hepatic steatosis and inflammation and suppressing enhanced gluconeogenesis induced by high-fat and high-fructose diet
-
Wada T, Kenmochi H, Miyashita Y et al. Spironolactone improves glucose and lipid metabolism by ameliorating hepatic steatosis and inflammation and suppressing enhanced gluconeogenesis induced by high-fat and high-fructose diet. Endocrinology 2010; 151: 2040-2049.
-
(2010)
Endocrinology
, vol.151
, pp. 2040-2049
-
-
Wada, T.1
Kenmochi, H.2
Miyashita, Y.3
-
15
-
-
33748752420
-
Insulin sensitivity in patients with primary aldosteronism: a follow-up study
-
Catena C, Lapenna R, Baroselli S et al. Insulin sensitivity in patients with primary aldosteronism: a follow-up study. J Clin Endocrinol Metab 2006; 91: 3457-3463.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 3457-3463
-
-
Catena, C.1
Lapenna, R.2
Baroselli, S.3
-
16
-
-
2942604308
-
Effect of spironolactone on endothelial function in patients with congestive heart failure on conventional medical therapy
-
Abiose AK, Mansoor GA, Barry M, Soucier R, Nair CK, Hager D. Effect of spironolactone on endothelial function in patients with congestive heart failure on conventional medical therapy. Am J Cardiol 2004; 93: 1564-1566.
-
(2004)
Am J Cardiol
, vol.93
, pp. 1564-1566
-
-
Abiose, A.K.1
Mansoor, G.A.2
Barry, M.3
Soucier, R.4
Nair, C.K.5
Hager, D.6
-
17
-
-
0033818040
-
Troglitazone reduces reactive oxygen species generation by leukocytes and lipid peroxidation and improves flow-mediated vasodilatation in obese subjects
-
Garg R, Kumbkarni Y, Aljada A et al. Troglitazone reduces reactive oxygen species generation by leukocytes and lipid peroxidation and improves flow-mediated vasodilatation in obese subjects. Hypertension 2000; 36: 430-435.
-
(2000)
Hypertension
, vol.36
, pp. 430-435
-
-
Garg, R.1
Kumbkarni, Y.2
Aljada, A.3
-
18
-
-
0032783492
-
Renal response to captopril reflects state of local renin system in healthy humans
-
Fisher ND, Price DA, Litchfield WR, Williams GH, Hollenberg NK. Renal response to captopril reflects state of local renin system in healthy humans. Kidney Int 1999; 56: 635-641.
-
(1999)
Kidney Int
, vol.56
, pp. 635-641
-
-
Fisher, N.D.1
Price, D.A.2
Litchfield, W.R.3
Williams, G.H.4
Hollenberg, N.K.5
-
19
-
-
0032821965
-
Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp
-
Matsuda M, DeFronzo RA. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 1999; 22: 1462-1470.
-
(1999)
Diabetes Care
, vol.22
, pp. 1462-1470
-
-
Matsuda, M.1
DeFronzo, R.A.2
-
20
-
-
84890453201
-
Mineralocorticoid receptor throughout the vessel: a key to vascular dysfunction in obesity
-
Pojoga LH, Baudrand R, Adler GK. Mineralocorticoid receptor throughout the vessel: a key to vascular dysfunction in obesity. Eur Heart J 2013; 34: 3475-3477.
-
(2013)
Eur Heart J
, vol.34
, pp. 3475-3477
-
-
Pojoga, L.H.1
Baudrand, R.2
Adler, G.K.3
-
21
-
-
84873106278
-
Role of Rac1-mineralocorticoid-receptor signalling in renal and cardiac disease
-
Nagase M, Fujita T. Role of Rac1-mineralocorticoid-receptor signalling in renal and cardiac disease. Nat Rev Nephrol 2013; 9: 86-98.
-
(2013)
Nat Rev Nephrol
, vol.9
, pp. 86-98
-
-
Nagase, M.1
Fujita, T.2
-
22
-
-
0034651798
-
Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure
-
Farquharson CA, Struthers AD. Spironolactone increases nitric oxide bioactivity, improves endothelial vasodilator dysfunction, and suppresses vascular angiotensin I/angiotensin II conversion in patients with chronic heart failure. Circulation 2000; 101: 594-597.
-
(2000)
Circulation
, vol.101
, pp. 594-597
-
-
Farquharson, C.A.1
Struthers, A.D.2
-
23
-
-
79960916860
-
Aldosterone decreases glucose-stimulated insulin secretion in vivo in mice and in murine islets
-
Luther JM, Luo P, Kreger MT et al. Aldosterone decreases glucose-stimulated insulin secretion in vivo in mice and in murine islets. Diabetologia 2011; 54: 2152-2163.
-
(2011)
Diabetologia
, vol.54
, pp. 2152-2163
-
-
Luther, J.M.1
Luo, P.2
Kreger, M.T.3
-
24
-
-
77956265232
-
Mineralocorticoid receptor antagonists and the metabolic syndrome
-
Tirosh A, Garg R, Adler GK. Mineralocorticoid receptor antagonists and the metabolic syndrome. Curr Hypertens Rep 2010; 12: 252-257.
-
(2010)
Curr Hypertens Rep
, vol.12
, pp. 252-257
-
-
Tirosh, A.1
Garg, R.2
Adler, G.K.3
-
25
-
-
33745995176
-
Insulin sensitivity indices: a proposal of cut-off points for simple identification of insulin-resistant subjects
-
Radikova Z, Koska J, Huckova M et al. Insulin sensitivity indices: a proposal of cut-off points for simple identification of insulin-resistant subjects. Exp Clin Endocrinol Diabetes 2006; 114: 249-256.
-
(2006)
Exp Clin Endocrinol Diabetes
, vol.114
, pp. 249-256
-
-
Radikova, Z.1
Koska, J.2
Huckova, M.3
-
26
-
-
84867885350
-
Spironolactone, but not eplerenone, impairs glucose tolerance in a rat model of metabolic syndrome
-
Homma T, Fujisawa M, Arai K, Ishii M, Sada T, Ikeda M. Spironolactone, but not eplerenone, impairs glucose tolerance in a rat model of metabolic syndrome. J Vet Med Sci 2012; 74: 1015-1022.
-
(2012)
J Vet Med Sci
, vol.74
, pp. 1015-1022
-
-
Homma, T.1
Fujisawa, M.2
Arai, K.3
Ishii, M.4
Sada, T.5
Ikeda, M.6
-
27
-
-
34447136169
-
Beneficial effects of eplerenone versus hydrochlorothiazide on coronary circulatory function in patients with diabetes mellitus
-
Joffe HV, Kwong RY, Gerhard-Herman MD, Rice C, Feldman K, Adler GK. Beneficial effects of eplerenone versus hydrochlorothiazide on coronary circulatory function in patients with diabetes mellitus. J Clin Endocrinol Metab 2007; 92: 2552-2558.
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 2552-2558
-
-
Joffe, H.V.1
Kwong, R.Y.2
Gerhard-Herman, M.D.3
Rice, C.4
Feldman, K.5
Adler, G.K.6
-
28
-
-
11144344961
-
Spironolactone impairs endothelial function and heart rate variability in patients with type 2 diabetes
-
Davies JI, Band M, Morris A, Struthers AD. Spironolactone impairs endothelial function and heart rate variability in patients with type 2 diabetes. Diabetologia 2004; 47: 1687-1694.
-
(2004)
Diabetologia
, vol.47
, pp. 1687-1694
-
-
Davies, J.I.1
Band, M.2
Morris, A.3
Struthers, A.D.4
-
29
-
-
0345012078
-
Lifestyle modification improves endothelial function in obese subjects with the insulin resistance syndrome
-
Hamdy O, Ledbury S, Mullooly C et al. Lifestyle modification improves endothelial function in obese subjects with the insulin resistance syndrome. Diabetes Care 2003; 26: 2119-2125.
-
(2003)
Diabetes Care
, vol.26
, pp. 2119-2125
-
-
Hamdy, O.1
Ledbury, S.2
Mullooly, C.3
|