Renal response to captopril reflects state of local renin system in healthy humans

Kidney International

Volumn 56, Issue 2, 1999, Pages 635-641

  Fisher, Naomi D L ^a   Price, Deborah A ^a   Litchfield, W Reid ^a   Williams, Gordon H ^a   Hollenberg, Norman K ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Angiotensin converting enzyme inhibition; Angiotensin II; Angiotensinogen; Hypertension; Renal circulation; Sodium; Vasoconstriction

Indexed keywords

ANGIOTENSINOGEN; CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR;

ADULT; ARTICLE; DRUG RESPONSE; ENZYME INHIBITION; HUMAN; HYPERTENSION; KIDNEY CIRCULATION; KIDNEY CLEARANCE; KIDNEY PLASMA FLOW; MALE; MOUSE; NORMAL HUMAN; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SODIUM RESTRICTION; VASOCONSTRICTION;

EID: 0032783492     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.1999.00579.x     Document Type: Article

References (26)

1. 1. SHOBACK DM, WILLIAMS GH, MOORE TH, DLUHY RG, PODOLSKY S. HOLLENBERG NK: Defect in the sodium-modulated tissue responsiveness to angiotensin II in essential hypertension. J Clin Invest 72:2115-2124, 1983
2. 2. LEWIS EJ, HUNSICKER LG, BAIN RP, ROHDE RD: The effect of angiotensin-converting enzyme inhibition on diabetic nephropathy. The Collaborative Study Group. N Engl J Med 329:1456-1462, 1993
3. 3. COHN JN, JOHNSON G, ZIESCHE S, COBB F, FRANCIS G, TRISTANI F, SMITH R, DUNKMAN WB, WEB H, WONG M: A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic CHF. N Engl J Med 325:303-310, 1991
4. 4. SOLVD INVESTIGATORS: Effect of enalapril on survival in patients with reduced left ventricular function and CHF. N Engl J Med 325:293-302, 1991
5. 5. JEUNEMAITRE X, SOUBRIER F, KOTELEVTSEV Y, LIFTON RP, WILLIAMS CS, CHARRU A, HUNT SC, HOPKINS PN, WILLIAMS RR, LALOUEL JM, CORVOL P: Molecular basis of human hypertension. Role of angiotensinogen. Cell 71:169-178, 1992
6. 6. DORIA A, WARRAN JH, KROLEWSKI AS: Genetic predisposition to diabetic nephropathy: Evidence for a role of the angiotensin I converting enzyme gene. Diabetes 43:384-388, 1994
7. 7. MARRE, M, JEUNEMATIRE X, GALLOIS Y, RODIER M, CHATELLIER G, SERT C, DUSSELIER L, KAHAI Z, CHAILLOUS L, HALIME S, MULLER A, SACKMANN H, BAUDUCEAU B, BLED F, PASSA P, ALHENC-GELAS F: Contribution of genetic polymorphism in the renin-angiotensin system to the development of renal complications in insulin-dependent diabetes: Genetique de la Nephropathie Diabetique (GENEDIAB) study group. J Clin Invest 99:1585-1595, 1997
8. 8. PARVING HH, TARNOW L, ROSSING P: Genetics of diabetic nephropathy. J Am Soc Nephrol 7:2509-2517, 1996
9. 9. SCHMIDT S, RITZ E: Genetic determinants of diabetic renal disease and their impact on therapeutic interventions. Kidney Int 63(Suppl):S27-S31, 1997
10. 10. WILLIAMS GH, DLUHY RG, LIFTON RP, MOORE TJ, GLEASON R, WILLIAMS R, HUNT SC, HOPKINS PN, HOLLENBERG NK: Non-modulation as an intermediate phenotype in essential hypertension. Hypertension 20:788-796, 1992
11. 11. HOPKINS PN, LIFTON RP, HOLLENBERG NK, JEUNEMAITRE X, HAELOUIN MC, SKUPPIN J, WILLIAMS CS, DLUHY RG, LALOUEL JM, WILLIAMS RR, WILLIAMS GH: Blunted renal vascular response to angiotensin II is associated with a common variant of the angiotensinogen gene and obesity. J Hypertens 14:199-207, 1996
12. 12. REDGRAVE J, RABINOWE S, HOLLENBERG NK, WILLIAMS G: Correction of abnormal renal blood flow response to angiotensin II by converting enzyme inhibition in essential hypertensives. J Clin Invest 4:1285-1290, 1985
13. 13. DE'OLIVEIRA J, PRICE D, FISHER NDL, ALLAN D, MCNIGHT J, WILLIAMS GH, HOLLENBERG NK: Autonomy of the renin system in type II diabetes mellitus: Dietary sodium and renal hemodynamic responses to ACE inhibition. Kidney Int 52:771-777, 1997
14. 14. HOLLENBERG NK, MEGGS LG, WILLIAMS GH, GARNIC JD, HARRINGTON DP: Sodium intake and renal responses to captopril in normal man and in essential hypertension. Kidney Int 20:240-245, 1981
15. 15. FISHER NDL, ALLAN D, KIFOR I, GABOURY CL, WILLIAMS GH, MOORE TJ, HOLLENBERG NK: Responses to converting enzyme and renin inhibition: Role of angiotensin II in humans. Hypertension 23:44-51, 1994
16. 16. EMANUEL R, CAIN JP, WILLIAMS GH: Double antibody radioimmunoassay of renin activity and angiotEnsin II in human peripheral plasma. J Lab Clin Med 81:632-640, 1973
17. 17. ERDOS EG: Angiotensin I converting enzyme. Circ Res 36:247-255, 1975
18. 18. RAD L: Mechanisms of vascular injury. The emerging role of the endothelium. J Am Soc Nephrol 2(Suppl):S2-S8, 1991
19. 19. HOLLENBERG NK, PASSAN DR: Specificity of renal vasodilation with captopril: Saralasin prevents the response in the DOCA-treated, salt-loaded rabbit. Life Sci 31:329-334, 1982
20. 20. TONGCHUAN L, ZIMMERMAN BG: Relation between inhibition of renal angiotensin II production and hemodynamic effect of captopril in anaesthetized rabbit. J Hypertens 10:795-802, 1992
21. 21. RAVID M, SAVIN H, JUTRIN I, BENTAL T, KATZ B, LISHNER M: Long-term stabilizing effect of angiotensin-converting enzyme inhibition on plasma creatinine and on proteinuria in normotensive type II diabetic patients. Ann Intern Med 118:577-581, 1993
22. 22. SANCHEZ RA, GIMENEZ MI, MIGLIORINI M, GIANNONE C, RAMIREZ AJ, WEDER AB: Erythrocyte sodium-lithium countertransport in non-modulating offspring and essential hypertensive individuals: Response to enalapril. Hypertension 30:99-105, 1997
23. 23. DZAU VJ, RE R: Tissue angiotensin system in cardiovascular medicine: A paradigm shift? Circulation 89:493-498, 1994
24. 24. LIFTON RP, HOPKINS PN, WILLIAMS RR, HOLLENBERG NK, WILLIAMS GH, DLUHY RG: Evidence for heritability of non-modulating hypertension. Hypertension 13:884-889, 1989
25. 25. HOLLENBERG NK, FISHER NDL: Renal circulation and blockade of the renin-angiotensin system. Is angiotensin-converting enzyme inhibition the last word? Hypertension 26:602-609, 1995
26. 26. INGELFINGER JR, ZUO WM, FON EA, ELLISON KE, DZAU VJ: In situ hybridization evidence for angiotensinogen messenger RNA in the rat proximal tubule. An hypothesis for the intrarenal renin angiotensin system. J Clin Invest 85:417-423, 1990