Exploring the associations between genetic variants in genes encoding for subunits of calcium channel and subtypes of bipolar disorder

Journal of Affective Disorders

Volumn 157, Issue , 2014, Pages 80-86

  Jan, Wen Chi ^a   Yang, Shi Yi ^a   Chuang, Li Chung ^b   Lu, Ru Band ^c   Lu, Ming Kun ^d   Sun, H Sunny ^c   Kuo, Po Hsiu ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b CARDINAL TIEN COLLEGE OF HEALTHCARE AND MANAGEMENT   (Taiwan)

^c NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^d Jianan Mental Hospital   (Taiwan)

Author keywords

Associations; Bipolar disorder subtypes; Calcium channels; Gene gene interactions

Indexed keywords

CALCIUM CHANNEL;

ADULT; ARTICLE; BIPOLAR DISORDER; CACNA1C GENE; CACNA1E GENE; CACNB2 GENE; CACNG2 GENE; CONTROLLED STUDY; FEMALE; GENE; GENE FREQUENCY; GENE INTERACTION; GENETIC ASSOCIATION; GENETIC CODE; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; MACHINE LEARNING; MALE; MULTIFACTOR DIMENSIONALITY REDUCTION; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ASSOCIATIONS; BIPOLAR DISORDER SUBTYPES; CALCIUM CHANNELS; GENE-GENE INTERACTIONS;

ASIAN CONTINENTAL ANCESTRY GROUP; BIPOLAR DISORDER; CALCIUM CHANNELS; FEMALE; GENETIC LINKAGE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; TAIWAN;

EID: 84893771237     PISSN: 01650327     EISSN: 15732517     Source Type: Journal    
DOI: 10.1016/j.jad.2013.12.044     Document Type: Article

References (45)

1. J. Arikkath, and K.P. Campbell Auxiliary subunits: essential components of the voltage-gated calcium channel complex Curr. Opin. Neurobiol. 13 2003 298 307 (Pubitemid 36792242)
2. J.C. Barrett, B. Fry, J. Maller, and M.J. Daly Haploview: analysis and visualization of LD and haplotype maps Bioinformatics 21 2005 263 265 (Pubitemid 40202029)
3. A.E. Baum, N. Akula, M. Cabanero, I. Cardona, W. Corona, B. Klemens, T.G. Schulze, S. Cichon, M. Rietschel, M.M. Nothen, A. Georgi, J. Schumacher, M. Schwarz, R. Abou Jamra, S. Hofels, P. Propping, J. Satagopan, S.D. Detera-Wadleigh, J. Hardy, and F.J. McMahon A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder Mol. Psychiatry 13 2008 197 207
4. 2+ channels Physiol. Rev. 90 2010 1461 1506
5. F. Casamassima, A.C. Hay, A. Benedetti, L. Lattanzi, G.B. Cassano, and R.H. Perlis L-type calcium channels and psychiatric disorders: a brief review Am. J. Med. Genet. Part B, Neuropsychiatr. Genet.: Off. Publ. Int. Soc. Psychiatr. Genet. 153B 2010 1373 1390
6. F. Casamassima, J. Huang, M. Fava, G.S. Sachs, J.W. Smoller, G.B. Cassano, L. Lattanzi, J. Fagerness, J.P. Stange, and R.H. Perlis Phenotypic effects of a bipolar liability gene among individuals with major depressive disorder Am. J. Med. Genet. Part b, Neuropsychiatr. Genet.: Off. Publ. Int. Soc. Psychiatr. Genet. 153B 2010 303 309
7. S. Dai, D.D. Hall, and J.W. Hell Supramolecular assemblies and localized regulation of voltage-gated ion channels Physiol. Rev. 89 2009 411 452
8. M.A. Ferreira, M.C. O'Donovan, Y.A. Meng, I.R. Jones, D.M. Ruderfer, L. Jones, J. Fan, G. Kirov, R.H. Perlis, E.K. Green, J.W. Smoller, D. Grozeva, J. Stone, I. Nikolov, K. Chambert, M.L. Hamshere, V.L. Nimgaonkar, V. Moskvina, M.E. Thase, S. Caesar, G.S. Sachs, J. Franklin, K. Gordon-Smith, K.G. Ardlie, S.B. Gabriel, C. Fraser, B. Blumenstiel, M. Defelice, G. Breen, M. Gill, D.W. Morris, A. Elkin, W.J. Muir, K.A. McGhee, R. Williamson, D.J. MacIntyre, A.W. MacLean, C.D. St, M. Robinson, M. Van Beck, A.C. Pereira, R. Kandaswamy, A. McQuillin, D.A. Collier, N.J. Bass, A.H. Young, J. Lawrence, I.N. Ferrier, A. Anjorin, A. Farmer, D. Curtis, E.M. Scolnick, P. McGuffin, M.J. Daly, A.P. Corvin, P.A. Holmans, D.H. Blackwood, H.M. Gurling, M.J. Owen, S.M. Purcell, P. Sklar, and N. Craddock Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder Nat. Genet. 40 2008 1056 1058
9. R.A. Fisher Combining independent tests of significance Am. Stat. 2 1948 30 31
10. J.J. Gargus Ion channel functional candidate genes in multigenic neuropsychiatric disease Biol. Psychiatry 60 2006 177 185
11. E.K. Green, D. Grozeva, I. Jones, L. Jones, G. Kirov, S. Caesar, K. Gordon-Smith, C. Fraser, L. Forty, E. Russell, M.L. Hamshere, V. Moskvina, I. Nikolov, A. Farmer, P. McGuffin, P.A. Holmans, M.J. Owen, M.C. O'Donovan, and N. Craddock The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia Mol. Psychiatry 15 2010 1016 1022
12. L.W. Hahn, M.D. Ritchie, and J.H. Moore Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions Bioinformatics 19 2003 376 382 (Pubitemid 36284937)
13. J. Holmkvist, D. Tojjar, P. Almgren, V. Lyssenko, C.M. Lindgren, B. Isomaa, T. Tuomi, G. Berglund, E. Renstrom, and L. Groop Polymorphisms in the gene encoding the voltage-dependent Ca(2+) channel Ca (V)2.3 (CACNA1E) are associated with type 2 diabetes and impaired insulin secretion Diabetologia 50 2007 2467 2475 (Pubitemid 350064246)
14. T. Kato Molecular neurobiology of bipolar disorder: a disease of 'mood-stabilizing neurons'? Trends Neurosci. 31 2008 495 503
15. R.C. Kessler, P. Berglund, O. Demler, R. Jin, K.R. Merikangas, and E.E. Walters Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication Arch. Gen. Psychiatry 62 2005 593 602 (Pubitemid 40973434)
16. R.C. Kessler, and T.B. Ustun The World mental health (WMH) Survey initiative version of the world health organization (WHO) Composite international diagnostic interview (CIDI) Int. J. Methods Psychiatr. Res. 13 2004 93 121
17. K.R. Krishnan Psychiatric and medical comorbidities of bipolar disorder Psychosom. Med. 67 2005 1 8
18. H. Le Hir, A. Nott, and M.J. Moore How introns influence and enhance eukaryotic gene expression Trends Biochem. Sci. 28 2003 215 220 (Pubitemid 36507161)
19. M.T. Lee, C.H. Chen, C.S. Lee, C.C. Chen, M.Y. Chong, W.C. Ouyang, N.Y. Chiu, L.J. Chuo, C.Y. Chen, H.K. Tan, H.Y. Lane, T.J. Chang, C.H. Lin, S.H. Jou, Y.M. Hou, J. Feng, T.J. Lai, C.L. Tung, T.J. Chen, C.J. Chang, F.W. Lung, C.K. Chen, I.S. Shiah, C.Y. Liu, P.R. Teng, K.H. Chen, L.J. Shen, C.S. Cheng, T.P. Chang, C.F. Li, C.H. Chou, K.H. Wang, C.S. Fann, J.Y. Wu, Y.T. Chen, and A.T. Cheng Genome-wide association study of bipolar I disorder in the Han Chinese population Mol. Psychiatry 16 2011 548 556
20. S.Y. Lee, S.L. Chen, Y.H. Chang, S.H. Chen, C.H. Chu, S.Y. Huang, N.S. Tzeng, C.L. Wang, I.H. Lee, T.L. Yeh, Y.K. Yang, and R.B. Lu The ALDH2 and DRD2/ANKK1 genes interacted in bipolar II but not bipolar I disorder. Pharmacogenetics and genomics 2010 500 506
21. S.Y. Lee, S.L. Chen, S.H. Chen, S.Y. Huang, N.S. Tzeng, Y.H. Chang, C.L. Wang, I.H. Lee, T.L. Yeh, Y.K. Yang, and R.B. Lu The COMT and DRD3 genes interacted in bipolar I but not bipolar II disorder. The world journal of biological psychiatry: the official journal of the World Federation of Societies of Biological Psychiatry 12 2011 385 391
22. R.H. Lenox, and L. Wang Molecular basis of lithium action: integration of lithium-responsive signaling and gene expression networks Mol. Psychiatry 8 2003 135 144 (Pubitemid 36315220)
23. D. Levy, G.B. Ehret, K. Rice, G.C. Verwoert, L.J. Launer, A. Dehghan, N.L. Glazer, A.C. Morrison, A.D. Johnson, T. Aspelund, Y. Aulchenko, T. Lumley, A. Kottgen, R.S. Vasan, F. Rivadeneira, G. Eiriksdottir, X. Guo, D.E. Arking, G.F. Mitchell, F.U. Mattace-Raso, A.V. Smith, K. Taylor, R.B. Scharpf, S.J. Hwang, E.J. Sijbrands, J. Bis, T.B. Harris, S.K. Ganesh, C.J. O'Donnell, A. Hofman, J.I. Rotter, J. Coresh, E.J. Benjamin, A.G. Uitterlinden, G. Heiss, C.S. Fox, J.C. Witteman, E. Boerwinkle, T.J. Wang, V. Gudnason, M.G. Larson, A. Chakravarti, B.M. Psaty, and C.M. van Duijn Genome-wide association study of blood pressure and hypertension Nat. Genet. 41 2009 677 687
24. Y. Li, C. Willer, S. Sanna, and G Abecasis Genotype imputation Annu. Rev. Genomics Hum. Genet. 10 2009 387 406
25. X. Liang, M. Slifer, E.R. Martin, N. Schnetz-Boutaud, J. Bartlett, B. Anderson, S. Zuchner, H. Gwirtsman, J.R. Gilbert, M.A. Pericak-Vance, and J.L. Haines Genomic convergence to identify candidate genes for Alzheimer disease on chromosome 10 Hum. Mutat. 30 2009 463 471
26. Y.M. Lin, F. Davamani, W.C. Yang, T.J. Lai, and H.S. Sun Association analysis of monoamine oxidase A gene and bipolar affective disorder in Han Chinese Behav. Brain Funct. 4 2008 21
27. Y.L. Liu, C.S. Fann, C.M. Liu, W.J. Chen, J.Y. Wu, S.I. Hung, C.H. Chen, Y.S. Jou, S.K. Liu, T.J. Hwang, M.H. Hsieh, C.C. Chang, W.C. Yang, J.J. Lin, F.H. Chou, S.V. Faraone, M.T. Tsuang, and H.G. Hwu RASD2, MYH9, and CACNG2 genes at chromosome 22q12 associated with the subgroup of schizophrenia with non-deficit in sustained attention and executive function Biol. Psychiatry 64 2008 789 796
28. R.B. Lu, J.F. Lee, S.Y. Huang, S.Y. Lee, Y.H. Chang, P.H. Kuo, S.L. Chen, S.H. Chen, C.H. Chu, W.W. Lin, P.L. Wu, and H.C. Ko Interaction between ALDHâ FOR VERIFICATION 1 and DRD2/ANKK1 TaqI A1A1 genes may be associated with antisocial personality disorder not co-morbid with alcoholism Addict. Biol. 17 2012 865 874
29. P. McGuffin, F. Rijsdijk, M. Andrew, P. Sham, R. Katz, and A. Cardno The heritability of bipolar affective disorder and the genetic relationship to unipolar depression Arch. Gen. Psychiatry 60 2003 497 502 (Pubitemid 36539059)
30. F.J. McMahon, S.G. Simpson, M.G. McInnis, J.A. Badner, D.F. MacKinnon, and J.R. DePaulo Linkage of bipolar disorder to chromosome 18q and the validity of bipolar II disorder Arch. Gen. Psychiatry 58 2001 1025 1031 (Pubitemid 33051827)
31. M.B. McQueen, B. Devlin, S.V. Faraone, V.L. Nimgaonkar, P. Sklar, J.W. Smoller, R. Abou Jamra, M. Albus, S.A. Bacanu, M. Baron, T.B. Barrett, W. Berrettini, D. Blacker, W. Byerley, S. Cichon, W. Coryell, N. Craddock, M.J. Daly, J.R. Depaulo, H.J. Edenberg, T. Foroud, M. Gill, T.C. Gilliam, M. Hamshere, I. Jones, L. Jones, S.H. Juo, J.R. Kelsoe, D. Lambert, C. Lange, B. Lerer, J. Liu, W. Maier, J.D. Mackinnon, M.G. McInnis, F.J. McMahon, D.L. Murphy, M.M. Nothen, J.I. Nurnberger, C.N. Pato, M.T. Pato, J.B. Potash, P. Propping, A.E. Pulver, J.P. Rice, M. Rietschel, W. Scheftner, J. Schumacher, R. Segurado, K. Van Steen, W. Xie, P.P. Zandi, and N.M. Laird Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. Am. J. Hum. Genet. 77 2005 582 595 (Pubitemid 41361605)
32. A.C. Need, R.S. Keefe, D. Ge, I. Grossman, S. Dickson, J.P. McEvoy, and D.B. Goldstein Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis Eur. J. Hum. Genet. 17 2009 946 957
33. M.C. Ng, W.Y. So, V.K. Lam, C.S. Cockram, G.I. Bell, N.J. Cox, and J.C. Chan Genome-wide scan for metabolic syndrome and related quantitative traits in Hong Kong Chinese and confirmation of a susceptibility locus on chromosome 1q21-q25 Diabetes 53 2004 2676 2683 (Pubitemid 39299278)
34. E.A. Nwulia, K. Miao, P.P. Zandi, D.F. Mackinnon, J.R. DePaulo Jr., and M.G. McInnis Genome-wide scan of bipolar II disorder Bipolar Disord. 9 2007 580 588 (Pubitemid 47365625)
35. W.H. Pan, C.S. Fann, J.Y. Wu, Y.T. Hung, M.S. Ho, T.H. Tai, Y.J. Chen, C.J. Liao, M.L. Yang, A.T. Cheng, and Y.T. Chen Han Chinese cell and genome bank in Taiwan: purpose, design and ethical considerations Hum. Hered. 61 2006 27 30 (Pubitemid 43800650)
36. S. Purcell, B. Neale, K. Todd-Brown, L. Thomas, M.A. Ferreira, D. Bender, J. Maller, P. Sklar, P.I. de Bakker, M.J. Daly, and P.C. Sham PLINK: a tool set for whole-genome association and population-based linkage analyses Am. J. Hum. Genet. 81 2007 559 575 (Pubitemid 47330214)
37. R. Segurado, S.D. Detera-Wadleigh, D.F. Levinson, C.M. Lewis, M. Gill, J.I. Nurnberger Jr., N. Craddock, J.R. DePaulo, M. Baron, E.S. Gershon, J. Ekholm, S. Cichon, G. Turecki, S. Claes, J.R. Kelsoe, P.R. Schofield, R.F. Badenhop, J. Morissette, H. Coon, D. Blackwood, L.A. McInnes, T. Foroud, H.J. Edenberg, T. Reich, J.P. Rice, A. Goate, M.G. McInnis, F.J. McMahon, J.A. Badner, L.R. Goldin, P. Bennett, V.L. Willour, P.P. Zandi, J. Liu, C. Gilliam, S.H. Juo, W.H. Berrettini, T. Yoshikawa, L. Peltonen, J. Lonnqvist, M.M. Nothen, J. Schumacher, C. Windemuth, M. Rietschel, P. Propping, W. Maier, M. Alda, P. Grof, G.A. Rouleau, J. Del-Favero, C. Van Broeckhoven, J. Mendlewicz, R. Adolfsson, M.A. Spence, H. Luebbert, L.J. Adams, J.A. Donald, P.B. Mitchell, N. Barden, E. Shink, W. Byerley, W. Muir, P.M. Visscher, S. Macgregor, H. Gurling, G. Kalsi, A. McQuillin, M.A. Escamilla, V.I. Reus, P. Leon, N.B. Freimer, H. Ewald, T.A. Kruse, O. Mors, U. Radhakrishna, J.L. Blouin, S.E. Antonarakis, and N. Akarsu Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: bipolar disorder Am. J. Hum. Genet. 73 2003 49 62 (Pubitemid 36793779)
38. A. Serretti, and L. Mandelli The genetics of bipolar disorder: genome 'hot regions,' genes, new potential candidates and future directions Mol. Psychiatry 13 2008 742 771 (Pubitemid 352032111)
39. G. Silberberg, A. Levit, D. Collier, D. St Clair, J. Munro, R.W. Kerwin, L. Tondo, G. Floris, G. Breen, and R. Navon Stargazin involvement with bipolar disorder and response to lithium treatment Pharmacogenet. Genomics 18 2008 403 412 (Pubitemid 351535941)
40. P. Sklar, J.W. Smoller, J. Fan, M.A. Ferreira, R.H. Perlis, K. Chambert, V.L. Nimgaonkar, M.B. McQueen, S.V. Faraone, A. Kirby, P.I. de Bakker, M.N. Ogdie, M.E. Thase, G.S. Sachs, K. Todd-Brown, S.B. Gabriel, C. Sougnez, C. Gates, B. Blumenstiel, M. Defelice, K.G. Ardlie, J. Franklin, W.J. Muir, K.A. McGhee, D.J. MacIntyre, A. McLean, M. VanBeck, A. McQuillin, N.J. Bass, M. Robinson, J. Lawrence, A. Anjorin, D. Curtis, E.M. Scolnick, M.J. Daly, D.H. Blackwood, H.M. Gurling, and S.M. Purcell Whole-genome association study of bipolar disorder Mol. Psychiatry 13 2008 558 569 (Pubitemid 351704939)
41. J.W. Smoller, N. Craddock, K. Kendler, P.H. Lee, B.M. Neale, J.I. Nurnberger, S. Ripke, S. Santangelo, and P.F. Sullivan Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis Lancet 381 2013 1371 1379
42. H.C. Tsai, M.K. Lu, Y.K. Yang, M.C. Huang, T.L. Yeh, W.J. Chen, R.B. Lu, and P.H. Kuo Empirically derived subgroups of bipolar I patients with different comorbidity patterns of anxiety and substance use disorders in Han Chinese population J. Affect. Disord. 136 2012 81 89
43. H. Vacher, D.P. Mohapatra, and J.S. Trimmer Localization and targeting of voltage-dependent ion channels in mammalian central neurons Physiol. Rev. 88 2008 1407 1447
44. WTCCC Genome-wide association study of 14,000 cases of seven common diseases and 3000 shared controls Nature 447 2007 661 678
45. G. Zheng, B. Freidlin, Z. Li, and J.L. Gastwirth Choice of Scores in Trend Tests for Case-Control Studies of Candidate-Gene Associations Biom. J. 45 2003 335 348 10.1002/bimj.200390016 (Pubitemid 36571153)