Genome-wide scan of bipolar II disorder

Bipolar Disorders

Volumn 9, Issue 6, 2007, Pages 580-588

  Nwulia, Evaristus A ^a,d   Miao, Kuangyi ^a   Zandi, Peter P ^a,b   Mackinnon, Dean F ^a   Depaulo Jr , J Raymond ^a   Mcinnis, Melvin G ^a,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

^d HOWARD UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Bipolar disorder; Bipolar II disorder; Genehunter chromosomes; Genome wide scan; Non parametricanalysis; Phenotype

Indexed keywords

ARTICLE; BIPOLAR II DISORDER; CHROMOSOME 18Q; CHROMOSOME 9P; CHROMOSOME 9Q; CONTROLLED STUDY; FAMILY STUDY; GENETIC DATABASE; GENETIC LINKAGE; GENOME ANALYSIS; HUMAN; LINKAGE ANALYSIS; MAJOR CLINICAL STUDY; PEDIGREE ANALYSIS; PHENOTYPE; PRIORITY JOURNAL; PSYCHOLOGICAL MODEL; SAMPLING; SCORING SYSTEM;

AGE OF ONSET; BIPOLAR DISORDER; CHROMOSOMES, HUMAN; FEMALE; GENETIC LINKAGE; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; GENOME, HUMAN; HAPLOTYPES; HUMANS; MALE; PEDIGREE;

EID: 34548443748     PISSN: 13985647     EISSN: 13995618     Source Type: Journal    
DOI: 10.1111/j.1399-5618.2007.00437.x     Document Type: Article

References (71)

1. Regier DA, Farmer ME, Rae DS et al. Comorbidity of mental disorders with alcohol and other drug abuse results from the epidemiologic catchment area (ECA) study. JAMA 1990; 264: 2511-2518.
2. Akiskal HS, Bourgeois ML, Angst J, Post R, Moller H, Hirschfeld R. Re-evaluating the prevalence of and diagnostic composition within the broad clinical spectrum of bipolar disorders. J Affect Disord 2000; 59 (Suppl. 1): S5-S30.
3. Hirschfeld RM. The mood disorder questionnaire: A simple, patient-rated screening instrument for bipolar disorder. Prim Care Comp J Clin Psychiatry 2002; 4: 9-11.
4. Leonhard K. Pathogenesis of manic-depressive disease. Nervenarzt 1957; 28: 271-272.
5. Angst J, Felder W, Frey R, Stassen HH. The course of affective disorders I. change of diagnosis of monopolar, unipolar, and bipolar illness. Arch Psychiatr Nervenkr 1978; 226: 57.
6. Perris C. The concept of polarity and nosology of depressive psychoses. Arch Psicol Neurol Psichiatr 1968; 29: 111-128.
7. Dunner DL, Dwyer T, Fieve RR. Depressive symptoms in patients with unipolar and bipolar affective disorder. Compr Psychiatry 1976; 17: 447-451.
8. Akiskal HS. Subaffective disorders: Dysthymic, cyclothymic and bipolar II disorders in the 'borderline' realm. Psychiatr Clin North Am 1981; 4: 25-46.
9. Coryell W, Endicott J, Andreasen N, Keller M. Bipolar I, bipolar II, and nonbipolar major depression among the relatives of affectively ill probands. Am J Psychiatry 1985; 142: 817-821.
10. Simpson SG, Folstein SE, Meyers DA, McMahon FJ, Brusco DM, DePaulo Jr JR. Bipolar II: The most common bipolar phenotype? Am J Psychiatry 1993; 150: 901-903.
11. Gershon ES, Hamovit J, Guroff JJ et al. A family study of schizoaffective, bipolar I, bipolar II, unipolar, and normal control probands. Arch Gen Psychiatry 1982; 39: 1157-1167.
12. Coryell W, Endicott J, Reich T, Andreasen N, Keller M. A family study of bipolar II disorder. Br J Psychiatry 1984; 145: 49-54.
13. DePaulo Jr JR, Simpson SG, Gayle JO, Folstein SE. Bipolar II disorder in six sisters. J Affect Disord 1990; 19: 259-264.
14. Andreasen NC, Grove WM, Shapiro RW, Keller MB, Hirschfeld RMA, McDonald-Scott P. Reliability of lifetime diagnosis: A multicenter collaborative perspective. Arch Gen Psychiatry 1981; 38: 400-405.
15. Simpson SG, McMahon FJ, McInnis MG et al. Diagnostic reliability of bipolar II disorder. Arch Gen Psychiatry 2002; 59: 736-740.
16. McMahon FJ, Simpson SG, McInnis MG, Badner JA, MacKinnon DF, DePaulo JR. Linkage of bipolar disorder to chromosome 18q and the validity of bipolar II disorder. Arch Gen Psychiatry 2001; 58: 1025-1031.
17. Berrettini WH, Ferraro TN, Goldin LR et al. Chromosome 18 DNA markers and manic-depressive illness: Evidence for a susceptibility gene. Proc Natl Acad Sci U S A 1994; 91: 5918-5921.
18. Stine OC, Xu J, Koskela R et al. Evidence for linkage of bipolar disorder to chromosome 18 with a parent-of-origin effect. Am J Hum Genet 1995; 57: 1384-1394.
19. Nothen MM, Cichon S, Rohleder H et al. Evaluation of linkage of bipolar affective disorder to chromosome 18 in a sample of 57 German families. Mol Psychiatry 1999; 4: 76-84.
20. McMahon FJ, Hopkins PJ, Xu J et al. Linkage of bipolar affective disorder to chromosome 18 markers in a new pedigree series. Am J Hum Genet 1997; 61: 1397-1404.
21. Freimer NB, Reus VI, Escamilla MA et al. Genetic mapping using haplotype, association and linkage methods suggests a locus for severe bipolar disorder (BPI) at 18q22-q23. Nat Genet 1996; 12: 436-441.
22. Coon H, Hoff M, Holik J et al. Analysis of chromosome 18 DNA markers in multiplex pedigrees with manic depression. Biol Psychiatry 1996; 39: 689-696.
23. Fallin MD, Lasseter VK, Wolyniec PS et al. Genomewide linkage scan for bipolar-disorder susceptibility loci among ashkenazi Jewish families. Am J Hum Genet 2004; 75: 204-219.
24. Straub RE, Lehner T, Luo Y et al. A possible vulnerability locus for bipolar affective disorder on chromosome 21q22.3. Nat Genet 1994; 8: 291-296.
25. Smyth C, Kalsi G, Curtis D et al. Two-locus admixture linkage analysis of bipolar and unipolar affective disorder supports the presence of susceptibility loci on chromosomes 11p15 and 21q22. Genomics 1997; 39: 271-278.
26. Aita VM, Liu J, Knowles JA et al. A comprehensive linkage analysis of chromosome 21q22 supports prior evidence for a putative bipolar affective disorder locus. Am J Hum Genet 1999; 64: 210-217.
27. Kelsoe JR, Spence MA, Loetscher E et al. A genome survey indicates a possible susceptibility locus for bipolar disorder on chromosome 22. Proc Natl Acad Sci U S A 2001; 98: 585-590.
28. Blackwood DH, He L, Morris SW et al. A locus for bipolar affective disorder on chromosome 4p. Nat Genet 1996; 12: 427-430.
29. Detera-Wadleigh SD. Chromosomes 12 and 16 workshop. Am J Med Genet 1999; 88: 255-259.
30. Ewald H, Degn B, Mors O, Kruse TA. Support for the possible locus on chromosome 4p16 for bipolar affective disorder. Mol Psychiatry 1998; 3: 442-448.
31. Adams LJ, Mitchell PB, Fielder SL, Rosso A, Donald JA, Schofield PR. A susceptibility locus for bipolar affective disorder on chromosome 4q35. Am J Hum Genet 1998; 62: 1084-1091.
32. Kennedy JL, Basile VS, Macciardi FM. Chromosome 4 workshop summary: Sixth world congress on psychiatric genetics, bonn, germany, october 6-10, 1998. Am J Med Genet 1999; 88: 224-228.
33. Willour VL, Zandi PP, Huo Y et al. Genome scan of the fifty-six bipolar pedigrees from the NIMH genetics initiative replication sample: Chromosomes 4, 7, 9, 18, 19, 20, and 21. Am J Med Genet B Neuropsychiatr Genet 2003; 121: 21-27.
34. Dawson E, Parfitt E, Roberts Q et al. Linkage studies of bipolar disorder in the region of the darier's disease gene on chromosome 12q23-24.1. Am J Med Genet 1995; 60: 94-102.
35. Ewald H, Degn B, Mors O, Kruse TA. Significant linkage between bipolar affective disorder and chromosome 12q24. Psychiatr Genet 1998; 8: 131-140.
36. Detera-Wadleigh SD, Badner JA et al. A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2. Proc Natl Acad Sci U S A 1999; 96: 5604-5609.
37. Pulver AE, Nestadt G, Goldberg R et al. Psychotic illness in patients diagnosed with velo-cardio-facial syndrome and their relatives. J Nerv Ment Dis 1994; 182: 476-478.
38. Papolos DF, Faedda GL, Veit S et al. Bipolar spectrum disorders in patients diagnosed with velo-cardio-facial syndrome: Does a hemizygous deletion of chromosome 22q11 result in bipolar affective disorder? Am J Psychiatry 1996; 153: 1541-1547.
39. Pekkarinen P, Terwilliger J, Bredbacka PE, Lonnqvist J, Peltonen L. Evidence of a predisposing locus to bipolar disorder on Xq24-q27.1 in an extended Finnish pedigree. Genome Res 1995; 5: 105-115.
40. Bocchetta A, Piccardi MP, Martinelli V, Quesada G, Del Zompo M. Maternal inheritance of manic depression in hemizygotes for the G6PD-mediterranean mutation. indirect evidence for Xq28 transmission in sardinia. Psychiatr Genet 1999; 9: 63-68.
41. McInnis MG, Lan TH, Willour VL et al. Genome-wide scan of bipolar disorder in 65 pedigrees: Supportive evidence for linkage at 8q24, 18q22, 4q32, 2p12, and 13q12. Mol Psychiatry 2003; 8: 288-298.
42. Cichon S, Schumacher J, Muller DJ et al. A genome screen for genes predisposing to bipolar affective disorder detects a new susceptibility locus on 8q. Hum Mol Genet 2001; 10: 2933-2944.
43. Schumacher J, Cichon S, Rietschel M, Nothen MM, Propping P. Genetics of bipolar affective disorders. current status of research for identification of susceptibility genes. Nervenarzt 2002; 73: 581-592.
44. Lander ES, Green P. Construction of multilocus genetic linkage maps in humans. Proc Natl Acad Sci USA 1987; 84: 2363-2367.
45. Broman KW, Murray JC, Sheffield VC, White RL, Weber JL. Comprehensive human genetic maps: Individual and sex-specific variation in recombination. Am J Hum Genet 1998; 63: 861-869.
46. Kruglyak L, Daly MJ, Reeve-Daly MP, Lander ES. Parametric and nonparametric linkage analysis: A unified multipoint approach. Am J Hum Genet 1996; 58: 1347-1363.
47. Nyholt DR. GENEHUNTER: Your 'one-stop shop' for statistical genetic analysis? Hum Hered 2002; 53: 2-7.
48. Whittemore AS, Halpern J. A class of tests for linkage using affected pedigree members. Biometrics 1994; 50: 118-127.
49. Markianos K, Daly MJ, Kruglyak L. Efficient multipoint linkage analysis through reduction of inheritance space. Am J Hum Genet 2001; 68: 963-977.
50. Strauch K, Fimmers R, Kurz T, Deichmann KA, Wienker TF, Baur MP. Parametric and nonparametric multipoint linkage analysis with imprinting and two-locus-trait models: Application to mite sensitization. Am J Hum Genet 2000; 66: 1945-1957.
51. Abecasis GR, Cherny SS, Cookson WO, Cardon LR. Merlin-rapid analysis of dense genetic maps using sparse gene flow trees. Nat Genet 2002; 30: 97-101.
52. Badenhop RF, Moses MJ, Scimone A et al. A genome screen of 13 bipolar affective disorder pedigrees provides evidence for susceptibility loci on chromosome 3 as well as chromosomes 9, 13 and 19. Mol Psychiatry 2002; 7: 851-859.
53. Detera-Wadleigh SD, Badner JA, Yoshikawa T et al. Initial genome scan of the NIMH genetics initiative bipolar pedigrees: Chromosomes 4, 7, 9, 18, 19, 20, and 21q. Am J Med Genet 1997; 74: 254-262.
54. Venken T, Claes S, Sluijs S et al. Genomewide scan for affective disorder susceptibility loci in families of a northern swedish isolated population. Am J Hum Genet 2005; 76: 237-248.
55. Goldin LR, Gershon ES, Berrettini WH et al. Description of the genetic analysis workshop 10 bipolar disorder linkage data sets. Genet Epidemiol 1997; 14: 563-568.
56. Ewald H, Mors O, Koed K, Eiberg H, Kruse TA. Susceptibility loci for bipolar affective disorder on chromosome 18? A review and a study of Danish families. Psychiatr Genet 1997; 7: 1-12.
57. Liu J, Juo SH, Dewan A et al. Evidence for a putative bipolar disorder locus on 2p13-16 and other potential loci on 4q31, 7q34, 8q13, 9q31, 10q21-24, 13q32, 14q21 and 17q11-12. Mol Psychiatry 2003; 8: 333-342.
58. Craddock N, Jones I. Genetics of bipolar disorder. J Med Genet 1999; 36: 585-594.
59. Mundo E, Tharmalingham S, Neves-Pereira M et al. Evidence that the N -methyl- d -aspartate subunit 1 receptor gene (GRIN1) confers susceptibility to bipolar disorder. Mol Psychiatry 2003; 8: 241-245.
60. Heun R, Maier W. The distinction of bipolar II disorder from bipolar I and recurrent unipolar depression: Results of a controlled family study. Acta Psychiatr Scand 1993; 87: 279-284.
61. Coryell W, Endicott J, Maser JD, Keller MB, Leon AC, Akiskal HS. Long-term stability of polarity distinctions in the affective disorders. Am J Psychiatry 1995; 152: 385-390.
62. Coryell W. Bipolar II disorder: A progress report. J Affect Disord 1996; 41: 159-162.
63. Hadjipavlou G, Mok H, Yatham LN. Bipolar II disorder: An overview of recent developments. Can J Psychiatry 2004; 49: 802-812.
64. Parker G. Highlighting bipolar II disorder. Can J Psychiatry 2004; 49: 791-793.
65. Lozano BE, Johnson SL. Can personality traits predict increases in manic and depressive symptoms? J Affect Disord 2001; 63: 103-111.
66. Sen S, Nesse RM, Stoltenberg SF et al. A BDNF coding variant is associated with the NEO personality inventory domain neuroticism, a risk factor for depression. Neuropsychopharmacology 2003; 28: 397-401.
67. Sen S, Burmeister M, Ghosh D. Meta-analysis of the association between a serotonin transporter promoter polymorphism (5-HTTLPR) and anxiety-related personality traits. Am J Med Genet B Neuropsychiatr Genet 2004; 127: 85-89.
68. Samochowiec J, Syrek S, Michal P et al. Polymorphisms in the serotonin transporter and monoamine oxidase A genes and their relationship to personality traits measured by the temperament and character inventory and NEO five-factor inventory in healthy volunteers. Neuropsychobiology 2004; 50: 174-181.
69. Kendler KS, Kuhn J, Prescott CA. The interrelationship of neuroticism, sex, and stressful life events in the prediction of episodes of major depression. Am J Psychiatry 2004; 161: 631-636.
70. Nash MW, Huezo-Diaz P, Williamson RJ et al. Genome-wide linkage analysis of a composite index of neuroticism and mood-related scales in extreme selected sibships. Hum Mol Genet 2004; 13: 2173-2182.
71. Flint J. The genetic basis of neuroticism. Neurosci Biobehav Rev 2004; 28: 307-316.