The COMT and DRD3 genes interacted in bipolar i but not bipolar II disorder

World Journal of Biological Psychiatry

Volumn 12, Issue 5, 2011, Pages 385-391

  Lee, Sheng Yu ^a,b   Chen, Shiou Lan ^a   Chen, Shih Heng ^a   Huang, San Yuan ^c   Tzeng, Nian Sheng ^c   Chang, Yun Hsuan ^a   Wang, Chen Lin ^b   Lee, I Hui ^a,b   Yeh, Tzung Lieh ^a,b   Yang, Yen Kuang ^a,b   Lu, Ru Band ^a,b  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

^c TRI SERVICE GENERAL HOSPITAL   (Taiwan)

Author keywords

Bipolar disorder; COMT; DRD3; Gene; Interaction

Indexed keywords

CATECHOL METHYLTRANSFERASE; DOPAMINE 3 RECEPTOR;

ADULT; ARTICLE; BIPOLAR I DISORDER; BIPOLAR II DISORDER; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GENE INTERACTION; GENETIC ANALYSIS; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT;

ADULT; BIPOLAR DISORDER; CASE-CONTROL STUDIES; CATECHOL O-METHYLTRANSFERASE; FEMALE; GENE FREQUENCY; GENES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LOGISTIC MODELS; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, DOPAMINE D3;

EID: 79960827211     PISSN: 15622975     EISSN: 18141412     Source Type: Journal    
DOI: 10.3109/15622975.2010.505298     Document Type: Article

References (58)

1. Akiskal HS. 1995. The bipolar spectrum: research and clinical perspectives. Encephale 21(Spec No 6):3-11.
2. Akiskal HS. 2003. Validating ' hard ' and ' soft ' phenotypes within the bipolar spectrum: continuity or discontinuity? J Affect Disord 73:1-5. (Pubitemid 36044627)
3. Akiskal HS, Pinto O. 1999. The evolving bipolar spectrum. Prototypes I, II, III, and I V. Psychiatr Clin North Am 22(3):517-534, vii. (Pubitemid 29463705)
4. Akiskal HS, Djenderedjian AM, Rosenthal RH, Khani MK. 1977. Cyclothymic disorder: validating criteria for inclusion in the bipolar affective group. Am J Psychiatry 134:1227-1233. (Pubitemid 8228220)
5. Akiskal HS, Rosenthal RH, Rosenthal TL, Kashgarian M, Khani MK, Puzantian VR. 1979. Differentiation of primary affective illness from situational, symptomatic, and secondary depressions. Arch Gen Psychiatry 36:635-643. (Pubitemid 10117064)
6. American Psychiatric Association. 2000. Diagnostic and statistical manual of mental disorders. 4th ed. (DSM-IV). Washington, DC: American Psychiatric Association.
7. Angst J. 1998. The emerging epidemiology of hypomania and bipolar II disorder. J Affect Disord 50:143-151. (Pubitemid 28551784)
8. Angst J, Gamma A, Benazzi F, Ajdacic V, Eich D, Rossler W. 2003. Toward a re-defi nition of subthreshold bipolarity: epidemiology and proposed criteria for bipolar II, minor bipolar disorders and hypomania. J Affect Disord 73:133-146. (Pubitemid 36044641)
9. Benazzi F. 2001. Is 4 days the minimum duration of hypomania in bipolar II disorder? Eur Arch Psychiatry Clin Neurosci 251:32-34. (Pubitemid 32267313)
10. Berk M, Dodd S. 2005. Bipolar II disorder: a review. Bipolar Disord 7:11-21. (Pubitemid 40227832)
11. Buchner A, Faul F, Erdfelder E. 1996. G-power: A Priori, Post Hoc, and Compromise Power Analyses for the Macintosh, Version 2.1.1. University of Trier, Trier, Germany.
12. Carlson CS, Eberle MA, Kruglyak L, Nickerson DA. 2004. Mapping complex disease loci in whole-genome association studies. Nature 429:446-452. (Pubitemid 38715138)
13. Chen J, Lipska BK, Halim N, Ma QD, Matsumoto M, Melhem Set al. 2004. Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain. Am J Hum Genet 75:807-821. (Pubitemid 39390488)
14. Chiaroni P, Azorin JM, Dassa D, Henry JM, Giudicelli S, Malthiery Yet al. 2000. Possible involvement of the dopamine D3 receptor locus in subtypes of bipolar affective disorder. Psy-chiatr Genet 10:43-49. (Pubitemid 30345192)
15. Coryell W, Endicott J, Reich T, Andreasen N, Keller M. 1984. A family study of bipolar II disorder. Br J Psychiatry 145:49-54. (Pubitemid 14120335)
16. Coryell W, Endicott J, Maser JD, Keller MB, Leon AC, Akiskal HS. 1995. Long-term stability of polarity distinctions in the affective disorders. Am J Psychiatry 152:385-390.
17. Cumming P, Brown E, Damsma G, Fibiger H. 1992. Formation and clearance of interstitial metabolites of dopamine and serotonin in the rat striatum: an in vivo microdialysis study. J Neurochem 59:1905-1914.
18. Elvidge G, Jones I, McCandless F, Asherson P, Owen MJ, Craddock N. 2001. Allelic variation of a BalI polymorphism in the DRD3 gene does not infl uence susceptibility to bipolar disorder: results of analysis and meta-analysis. Am J Med Genet 105:307-311. (Pubitemid 32578225)
19. Endicott J, Spitzer RL. 1987. A diagnostic interview: the schedule for affective disorders and schizophrenia. Arch Gen Psychiatry 35:837-844.
20. Faul F, Erdfelder E, Buchner A, Lang AG. 2009. Statistical power analyses using G ? Power 3.1: tests for correlation and regression analyses. Behav Res Methods 41:1149-60.
21. Huang SY, Lin WW, Ko HC, Lee JF, Wang TJ, Chou YHet al. 2004. Possible interaction of alcohol dehydrogenase and aldehyde dehydrogenase genes with the dopamine D2 receptor gene in anxiety-depressive alcohol dependence. Alcohol Clin Exp Res 28:374-384.
22. Jonsson E, Sedvall G, Brene S, Gustavsson JP, Geijer T, Terenius Let al. 1996. Dopamine-related genes and their relationships to monoamine metabolites in CSF. Biol Psychiatry 40:1032-1043. (Pubitemid 26391681)
23. Judd LL, Akiskal HS, Schettler PJ, Coryell W, Endicott J, Maser JDet al. 2003a. A prospective investigation of the natural history of the long-term weekly symptomatic status of bipolar II disorder. Arch Gen Psychiatry 60:261-269. (Pubitemid 36307437)
24. Judd LL, Akiskal HS, Schettler PJ, Coryell W, Maser J, Rice JAet al. 2003b. The comparative clinical phenotype and long term longitudinal episode course of bipolar I and II: a clinical spectrum or distinct disorders? J Affect Disord 73:19-32. (Pubitemid 36044629)
25. Kelsoe JR. 2003. Arguments for the genetic basis of the bipolar spectrum. J Affect Disord 73:183-197. (Pubitemid 36044646)
26. Kendler KS, Pedersen NL, Neale MC, Mathe AA. 1995. A pilot Swedish twin study of affective illness including hospital-and population-ascertained subsamples: results of model fi tting. Behav Genet 25:217-232.
27. Kirov G, Murphy KC, Arranz MJ, Jones I, McCandles F, Kunugi Het al. 1998. Low activity allele of catechol-O-meth-yltransferase gene associated with rapid cycling bipolar disorder. Mol Psychiatry 3:342-345. (Pubitemid 28379919)
28. Kirov G, Jones I, McCandless F, Craddock N, Owen MJ. 1999. Family-based association studies of bipolar disorder with candidate genes involved in dopamine neurotransmission: DBH, DAT1, COMT, DRD2, DRD3 and DRD5. Mol Psychiatry 4:558-565.
29. Kunugi H, Vallada HP, Hoda F, Kirov G, Gill M, Aitchison KJet al. 1997. No evidence for an association of affective disorders with high-or low-activity allele of catechol-o-methyltransferase gene. Biol Psychiatry 42(4):282-285. (Pubitemid 27325816)
30. Lachman HM, Papolos DF, Saito T, Yu YM, Szumlanski CL, Weinshilboum RM. 1996. Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders.Phar-macogenetics 6:243-250. (Pubitemid 26226317)
31. Lannfelt L, Sokoloff P, Martres M-P, Pilon C, Giros B, J ö nsson Eet al. 1992. Amino acid substitution in the dopamine D3 receptor gene as a useful polymorphism for investigating psychiatric disorders. Psychiatr Genet 2:249-256.
32. Li T, Vallada H, Curtis D, Arranz M, Xu K, Cai Get al. 1997. Catechol-O-methyltransferase Val158Met polymorphism: frequency analysis in Han Chinese subjects and allelic association of the low activity allele with bipolar affective disorder. Phar-macogenetics 7:349-353. (Pubitemid 27427543)
33. Lundstrom K, Turpin MP. 1996. Proposed schizophrenia-related gene polymorphism: expression of the Ser9Gly mutant human dopamine D3 receptor with the Semliki Forest virus system. Biochem Biophys Res Commun 225:1068-1072. (Pubitemid 26319228)
34. Mannisto PT, Kaakkola S. 1999. Catechol-O-methyltransferase (COMT): biochemistry, molecular biology, pharmacology, and clinical effi cacy of the new selective COMT inhibitors. Pharmacol Rev 51:593-628.
35. McGuffi n P, Rijsdijk F, Andrew M, Sham P, Katz R, Cardno A. 2003. The heritability of bipolar affective disorder and the genetic relationship to unipolar depression. Arch Gen Psychiatry. 60:497-502. (Pubitemid 36539059)
36. McMahon FJ, Simpson SG, McInnis MG, Badner JA, MacKinnon DF, DePaulo JR. 2001. Linkage of bipolar disorder to chromosome 18q and the validity of bipolar II disorder. Arch Gen Psychiatry 58:025-1031.
37. Mynett-Johnson LA, Murphy VE, Claffey E, Shields DC, McKeon P. 1998. Preliminary evidence of an association between bipolar disorder in females and the catechol-O-methyltransferase gene. Psychiatr Genet 8(4):221-225. (Pubitemid 28550213)
38. Nierenberg AA, Dougherty D, Rosenbaum JF. 1998. Dopamin-ergic agents and stimulants as antidepressant augmentation strategies. J Clin Psychiatry 59 Suppl 5:60-63; discussion 64.
39. Papolos DF, Veit S, Faedda GL, Saito T, Lachman HM. 1998. Ultra-ultra rapid cycling bipolar disorder is associated with the low activity catecholamine-O-methyltransferase allele. Mol Psychiatry 3:346-349. (Pubitemid 28379920)
40. Parsian A, Chakraverty S, Todd RD. 1995. Possible association between the dopamine D3 receptor gene and bipolar affective disorder. Am J Med Genet 60:234-237.
41. Quraishi S, Frangou S. 2002. Neuropsychology of bipolar disorder: a review. J Affect Disord 72:209-226. (Pubitemid 35351281)
42. Rihmer Z, Angst A. 2004. Mood Disorders: Epidemiology. In: Sadock BJ, Sadock VA, editors. Comprehensive textbook of psychiatry. 8th ed. Baltimore, MD: Lippincott Williams & Wilkins.
43. Sadovnick AD, Remick RA, Lam R, Zis AP, Yee IM, Huggins MJet al. 1994. Mood Disorders Service Genetic Database: morbidity risks for mood disorders in 3942 first-degree relatives of 671 index cases with single depression, recurrent depression, bipolar I or bipolar II. Am J Med Genet 54:132-140. (Pubitemid 24176739)
44. Saint-Cyr JA, Taylor AE, Lang AE. 1993. Neuropsychological and psychiatric side effects in the treatment of Parkinson's disease. Neurology 43(12 Suppl 6):S47-52. (Pubitemid 24006990)
45. Scharfetter J, Chaudhry HR, Hornik K, Fuchs K, Sieghart W, Kasper Set al. 1999. Dopamine D3 receptor gene polymorphism and response to clozapine in schizophrenic Pakastani patients. Eur Neuropsychopharmacol 10:17-20.
46. Schwartz JC, Diaz J, Pilon C, Sokoloff P. 2000. Possible implications of the dopamine D(3) receptor in schizophrenia and in antipsy-chotic drug actions. Brain Res Brain Res Rev 31:277-287. (Pubitemid 30136182)
47. Sesack SR, Hawrylak VA, Matus C, Guido MA, Levey AI. 1998. Dopamine axon varicosities in the prelimbic division of the rat prefrontal cortex exhibit sparse immunoreactivity for the dopamine transporter. J Neurosci 18:2697-2708. (Pubitemid 28141815)
48. Shaikh S, Ball D, Craddock N, Castle D, Hunt N, Mant Ret al. 1993. The dopamine D3 receptor gene: no association with bipolar affective disorder. J Med Genet 30:308-309. (Pubitemid 23120487)
49. Shaikh S, Collier DA, Sham PC, Ball D, Aitchison K, Vallada Het al. 1996. Allelic association between a Ser-9-Gly polymorphism in the dopamine D3 receptor gene and schizophrenia. Hum Genet 97:714-719. (Pubitemid 26150837)
50. Silverstone T, Romans-Clarkson S. 1989. Bipolar affective disorder: causes and prevention of relapse. Br J Psychiatry 154: 321-335. (Pubitemid 19091808)
51. Sokoloff P, Giros B, Martres MP, Bouthenet ML, Schwartz JC. 1990. Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics. Nature 347:146-151.
52. Souery D, Lipp O, Mahieu B, Mendelbaum K, De Martelaer V, Van Broeckhoven Cet al. 1996. Association study of bipolar disorder with candidate genes involved in catecholamine neu-rotransmission: DRD2, DRD3, DAT1, and TH genes. Am J Med Genet 67:551-555.
53. Spitzer RL, Endicott J, Williams JB. 1979. Research diagnostic criteria. Arch Gen Psychiatry 36:1381-1383.
54. Staner L, Hilger C, Hentges F, Monreal J, Hoffmann A, Couturier Met al. 1998. Association between novelty-seeking and the dopamine D3 receptor gene in bipolar patients: a preliminary report. Am J Med Genet 1998;81:192-194. (Pubitemid 28259102)
55. Taylor AE, Saint-Cyr JA. 1990. Depression in Parkinson's disease: reconciling physiological and psychological perspectives. J Neuropsychiatry Clin Neurosci 2(1):92-98. (Pubitemid 20125851)
56. Tokunaga K, Ishikawa K. 1992. Evidence for different sites of monoamine oxidase and catechol-O-methyltransferase in the striatum. Brain Res 575:164-166.
57. Tsuchiya KJ, Byrne M, Mortensen PB. 2003. Risk factors in relation to an emergence of bipolar disorder: a systematic review. Bipolar Disord 5:231-242. (Pubitemid 37009887)
58. Urata T, Takahashi N, Hakamata Y, Iijima Y, Kuwahara N, Ozaki Net al. 2007. Gene-gene interaction analysis of personality traits in a Japanese population using an electrochemical DNA array chip analysis. Neurosci Lett 414:209-212.