Synthetic phosphorylation of p38α recapitulates protein kinase activity

Journal of the American Chemical Society

Volumn 136, Issue 5, 2014, Pages 1698-1701

  Chooi, K Phin ^a   Galan, Sébastien R G ^a   Raj, Ritu ^a   McCullagh, James ^a   Mohammed, Shabaz ^a   Jones, Lyn H ^b   Davis, Benjamin G ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION LOOPS; COOPERATIVITY; DETAILED KINETICS; KINASE INHIBITION; KINETIC ANALYSIS; NATURAL PROTEINS; PROTEIN KINASE; PROTEIN KINASE ACTIVITIES;

CHEMICAL ACTIVATION; CHEMICAL MODIFICATION; ENZYMES; PROTEINS;

PHOSPHORYLATION;

CYSTEINE; MITOGEN ACTIVATED PROTEIN KINASE 14;

ARTICLE; CHEMICAL MODIFICATION; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME SUBSTRATE; IN VITRO STUDY; KINETICS; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; STOICHIOMETRY;

ACTIVATING TRANSCRIPTION FACTOR 2; BINDING SITES; CYSTEINE; ENZYME ACTIVATION; KINETICS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 14; MODELS, MOLECULAR; PHOSPHORYLATION; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY;

EID: 84893770102     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja4095318     Document Type: Article

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