메뉴 건너뛰기




Volumn 30, Issue 2, 2015, Pages 461-467

Improving the translation of animal ischemic stroke studies to humans

Author keywords

Animal models; Cerebrovascular disease; Clinical trial; Stroke

Indexed keywords

TISSUE PLASMINOGEN ACTIVATOR;

EID: 84893700628     PISSN: 08857490     EISSN: 15737365     Source Type: Journal    
DOI: 10.1007/s11011-014-9499-2     Document Type: Article
Times cited : (46)

References (70)
  • 2
    • 80052404082 scopus 로고    scopus 로고
    • Stroke Treatment Academic Industry Roundtable (STAIR) recommendations for maximizing the use of intravenous thrombolytics and expanding treatment options with intra-arterial and neuroprotective therapies
    • Albers GW, Goldstein LB, Hess DC, Wechsler LR, Furie KL, Gorelick PB, Hurn P, Liebeskind DS, Nogueira RG, Saver JL, Consortium SV (2011) Stroke Treatment Academic Industry Roundtable (STAIR) recommendations for maximizing the use of intravenous thrombolytics and expanding treatment options with intra-arterial and neuroprotective therapies. Stroke J Cereb Circ 42(9):2645–2650. doi:10.1161/STROKEAHA.111.618850
    • (2011) Stroke J Cereb Circ , vol.42 , Issue.9 , pp. 2645-2650
    • Albers, G.W.1    Goldstein, L.B.2    Hess, D.C.3    Wechsler, L.R.4    Furie, K.L.5    Gorelick, P.B.6    Hurn, P.7    Liebeskind, D.S.8    Nogueira, R.G.9    Saver, J.L.10    Consortium, S.V.11
  • 3
    • 66849101991 scopus 로고    scopus 로고
    • Potential animal models of lacunar stroke: a systematic review
    • Bailey EL, McCulloch J, Sudlow C, Wardlaw JM (2009) Potential animal models of lacunar stroke: a systematic review. Stroke J Cereb Circ 40(6):e451–e458. doi:10.1161/STROKEAHA.108.528430
    • (2009) Stroke J Cereb Circ , vol.40 , Issue.6 , pp. 451-458
    • Bailey, E.L.1    McCulloch, J.2    Sudlow, C.3    Wardlaw, J.M.4
  • 4
    • 80053196178 scopus 로고    scopus 로고
    • Is the spontaneously hypertensive stroke prone rat a pertinent model of sub cortical ischemic stroke? A systematic review
    • Bailey EL, Smith C, Sudlow CL, Wardlaw JM (2011a) Is the spontaneously hypertensive stroke prone rat a pertinent model of sub cortical ischemic stroke? A systematic review. Int J Stroke Off J Int Stroke Soc 6(5):434–444. doi:10.1111/j.1747-4949.2011.00659.x
    • (2011) Int J Stroke Off J Int Stroke Soc , vol.6 , Issue.5 , pp. 434-444
    • Bailey, E.L.1    Smith, C.2    Sudlow, C.L.3    Wardlaw, J.M.4
  • 5
    • 80055070713 scopus 로고    scopus 로고
    • Cerebral small vessel endothelial structural changes predate hypertension in stroke-prone spontaneously hypertensive rats: a blinded, controlled immunohistochemical study of 5- to 21-week-old rats
    • COI: 1:CAS:528:DC%2BC3MXhs1KjsbjK, PID: 21392049
    • Bailey EL, Wardlaw JM, Graham D, Dominiczak AF, Sudlow CL, Smith C (2011b) Cerebral small vessel endothelial structural changes predate hypertension in stroke-prone spontaneously hypertensive rats: a blinded, controlled immunohistochemical study of 5- to 21-week-old rats. Neuropathol Appl Neurobiol 37(7):711–726. doi:10.1111/j.1365-2990.2011.01170.x
    • (2011) Neuropathol Appl Neurobiol , vol.37 , Issue.7 , pp. 711-726
    • Bailey, E.L.1    Wardlaw, J.M.2    Graham, D.3    Dominiczak, A.F.4    Sudlow, C.L.5    Smith, C.6
  • 6
    • 33947526659 scopus 로고    scopus 로고
    • Outcomes validity and reliability of the modified Rankin scale: implications for stroke clinical trials: a literature review and synthesis
    • Banks JL, Marotta CA (2007) Outcomes validity and reliability of the modified Rankin scale: implications for stroke clinical trials: a literature review and synthesis. Stroke J Cereb Circ 38(3):1091–1096. doi:10.1161/01.STR.0000258355.23810.c6
    • (2007) Stroke J Cereb Circ , vol.38 , Issue.3 , pp. 1091-1096
    • Banks, J.L.1    Marotta, C.A.2
  • 7
    • 0029839695 scopus 로고    scopus 로고
    • Middle cerebral artery occlusion in the rat by intraluminal suture. Neurological and pathological evaluation of an improved model
    • COI: 1:STN:280:DyaK28znvVGktw%3D%3D, discussion 1623
    • Belayev L, Alonso OF, Busto R, Zhao W, Ginsberg MD (1996) Middle cerebral artery occlusion in the rat by intraluminal suture. Neurological and pathological evaluation of an improved model. Stroke J Cereb Circ 27(9):1616–1622, discussion 1623
    • (1996) Stroke J Cereb Circ , vol.27 , Issue.9 , pp. 1616-1622
    • Belayev, L.1    Alonso, O.F.2    Busto, R.3    Zhao, W.4    Ginsberg, M.D.5
  • 9
    • 0034745243 scopus 로고    scopus 로고
    • Comparison of TNK with wild-type tissue plasminogen activator in a rabbit embolic stroke model
    • COI: 1:CAS:528:DC%2BD3MXisVCjtrk%3D
    • Chapman DF, Lyden P, Lapchak PA, Nunez S, Thibodeaux H, Zivin J (2001) Comparison of TNK with wild-type tissue plasminogen activator in a rabbit embolic stroke model. Stroke J Cereb Circ 32(3):748–752
    • (2001) Stroke J Cereb Circ , vol.32 , Issue.3 , pp. 748-752
    • Chapman, D.F.1    Lyden, P.2    Lapchak, P.A.3    Nunez, S.4    Thibodeaux, H.5    Zivin, J.6
  • 10
    • 73949111725 scopus 로고    scopus 로고
    • Modes of defining atherosclerosis in mouse models: relative merits and evolving standards
    • PID: 19763919
    • Daugherty A, Lu H, Howatt DA, Rateri DL (2009) Modes of defining atherosclerosis in mouse models: relative merits and evolving standards. Methods Mol Biol 573:1–15. doi:10.1007/978-1-60761-247-6_1
    • (2009) Methods Mol Biol , vol.573 , pp. 1-15
    • Daugherty, A.1    Lu, H.2    Howatt, D.A.3    Rateri, D.L.4
  • 12
    • 84870941797 scopus 로고    scopus 로고
    • Prestroke modified rankin stroke scale has moderate interobserver reliability and validity in an acute stroke setting
    • Fearon P, McArthur KS, Garrity K, Graham LJ, McGroarty G, Vincent S, Quinn TJ (2012) Prestroke modified rankin stroke scale has moderate interobserver reliability and validity in an acute stroke setting. Stroke J Cereb Circ 43(12):3184–3188. doi:10.1161/STROKEAHA.112.670422
    • (2012) Stroke J Cereb Circ , vol.43 , Issue.12 , pp. 3184-3188
    • Fearon, P.1    McArthur, K.S.2    Garrity, K.3    Graham, L.J.4    McGroarty, G.5    Vincent, S.6    Quinn, T.J.7
  • 14
    • 0037975646 scopus 로고    scopus 로고
    • Recommendations for advancing development of acute stroke therapies: Stroke Therapy Academic Industry Roundtable 3
    • COI: 1:CAS:528:DC%2BD3sXktVKmsrc%3D
    • Fisher M, Stroke Therapy Academic Industry R (2003) Recommendations for advancing development of acute stroke therapies: Stroke Therapy Academic Industry Roundtable 3. Stroke J Cereb Circ 34(6):1539–1546. doi:10.1161/01.STR.0000072983.64326.53
    • (2003) Stroke J Cereb Circ , vol.34 , Issue.6 , pp. 1539-1546
    • Fisher, M.1    Stroke Therapy Academic Industry, R.2
  • 16
    • 33846633732 scopus 로고    scopus 로고
    • Recommendations from the STAIR V meeting on acute stroke trials, technology and outcomes
    • Fisher M, Hanley DF, Howard G, Jauch EC, Warach S, Group S (2007) Recommendations from the STAIR V meeting on acute stroke trials, technology and outcomes. Stroke J Cereb Circ 38(2):245–248. doi:10.1161/01.STR.0000255951.37434.aa
    • (2007) Stroke J Cereb Circ , vol.38 , Issue.2 , pp. 245-248
    • Fisher, M.1    Hanley, D.F.2    Howard, G.3    Jauch, E.C.4    Warach, S.5    Group, S.6
  • 18
    • 84865286421 scopus 로고    scopus 로고
    • Anesthetic management of patients with acute stroke
    • PID: 22901605
    • Flexman AM, Donovan AL, Gelb AW (2012) Anesthetic management of patients with acute stroke. Anesthesiol Clin 30(2):175–190. doi:10.1016/j.anclin.2012.04.002
    • (2012) Anesthesiol Clin , vol.30 , Issue.2 , pp. 175-190
    • Flexman, A.M.1    Donovan, A.L.2    Gelb, A.W.3
  • 19
    • 0021946451 scopus 로고
    • Laboratory-animal medicine changes and challenges
    • COI: 1:STN:280:DyaL2M7ltlaqtg%3D%3D, PID: 3884262
    • Fox JG (1985) Laboratory-animal medicine changes and challenges. Cornell Vet 75(1):159–170
    • (1985) Cornell Vet , vol.75 , Issue.1 , pp. 159-170
    • Fox, J.G.1
  • 20
    • 84867529644 scopus 로고    scopus 로고
    • Anesthesia for endovascular treatment of acute ischemic stroke
    • COI: 1:CAS:528:DC%2BC38XhsVWmtrnJ, PID: 23008394
    • Froehler MT, Fifi JT, Majid A, Bhatt A, Ouyang M, McDonagh DL (2012) Anesthesia for endovascular treatment of acute ischemic stroke. Neurology 79(13 Suppl 1):S167–S173. doi:10.1212/WNL.0b013e31826959c2
    • (2012) Neurology , vol.79 , pp. 167-173
    • Froehler, M.T.1    Fifi, J.T.2    Majid, A.3    Bhatt, A.4    Ouyang, M.5    McDonagh, D.L.6
  • 21
    • 80053318746 scopus 로고    scopus 로고
    • Preclinical evidence toward the use of ketamine for recombinant tissue-type plasminogen activator-mediated thrombolysis under anesthesia or sedation
    • COI: 1:CAS:528:DC%2BC3MXht1eqtLjI
    • Gakuba C, Gauberti M, Mazighi M, Defer G, Hanouz JL, Vivien D (2011) Preclinical evidence toward the use of ketamine for recombinant tissue-type plasminogen activator-mediated thrombolysis under anesthesia or sedation. Stroke J Cereb Circ 42(10):2947–2949. doi:10.1161/STROKEAHA.111.620468
    • (2011) Stroke J Cereb Circ , vol.42 , Issue.10 , pp. 2947-2949
    • Gakuba, C.1    Gauberti, M.2    Mazighi, M.3    Defer, G.4    Hanouz, J.L.5    Vivien, D.6
  • 22
    • 0036237417 scopus 로고    scopus 로고
    • Propofol anesthesia compared to awake reduces infarct size in rats
    • COI: 1:CAS:528:DC%2BD38Xkt1Cku7o%3D, PID: 11981160
    • Gelb AW, Bayona NA, Wilson JX, Cechetto DF (2002) Propofol anesthesia compared to awake reduces infarct size in rats. Anesthesiology 96(5):1183–1190
    • (2002) Anesthesiology , vol.96 , Issue.5 , pp. 1183-1190
    • Gelb, A.W.1    Bayona, N.A.2    Wilson, J.X.3    Cechetto, D.F.4
  • 25
    • 56649103770 scopus 로고    scopus 로고
    • Do in vivo experimental models reflect human cerebral small vessel disease? A systematic review
    • Hainsworth AH, Markus HS (2008) Do in vivo experimental models reflect human cerebral small vessel disease? A systematic review. J Cereb Blood Flow Metab Off J Int Soc Cereb Blood Flow Metab 28(12):1877–1891. doi:10.1038/jcbfm.2008.91
    • (2008) J Cereb Blood Flow Metab Off J Int Soc Cereb Blood Flow Metab , vol.28 , Issue.12 , pp. 1877-1891
    • Hainsworth, A.H.1    Markus, H.S.2
  • 26
    • 34548676161 scopus 로고    scopus 로고
    • Anesthetics and brain protection
    • PID: 17873591
    • Head BP, Patel P (2007) Anesthetics and brain protection. Curr Opin Anaesthesiol 20(5):395–399
    • (2007) Curr Opin Anaesthesiol , vol.20 , Issue.5 , pp. 395-399
    • Head, B.P.1    Patel, P.2
  • 27
    • 33646699101 scopus 로고    scopus 로고
    • Comparison of ischemic lesion evolution in embolic versus mechanical middle cerebral artery occlusion in Sprague Dawley rats using diffusion and perfusion imaging
    • Henninger N, Sicard KM, Schmidt KF, Bardutzky J, Fisher M (2006) Comparison of ischemic lesion evolution in embolic versus mechanical middle cerebral artery occlusion in Sprague Dawley rats using diffusion and perfusion imaging. Stroke J Cereb Circ 37(5):1283–1287. doi:10.1161/01.STR.0000217223.72193.98
    • (2006) Stroke J Cereb Circ , vol.37 , Issue.5 , pp. 1283-1287
    • Henninger, N.1    Sicard, K.M.2    Schmidt, K.F.3    Bardutzky, J.4    Fisher, M.5
  • 28
    • 84863496244 scopus 로고    scopus 로고
    • The two pathophysiologies of focal brain ischemia: implications for translational stroke research
    • Hossmann KA (2012) The two pathophysiologies of focal brain ischemia: implications for translational stroke research. J Cereb Blood Flow Metab Off J Int Soc Cereb Blood Flow Metab 32(7):1310–1316. doi:10.1038/jcbfm.2011.186
    • (2012) J Cereb Blood Flow Metab Off J Int Soc Cereb Blood Flow Metab , vol.32 , Issue.7 , pp. 1310-1316
    • Hossmann, K.A.1
  • 29
    • 0038691956 scopus 로고    scopus 로고
    • Efficacy of IV tissue plasminogen activator in acute stroke: does stroke subtype really matter?
    • COI: 1:CAS:528:DC%2BD3sXks1OktLg%3D, PID: 12847159
    • Hsia AW, Sachdev HS, Tomlinson J, Hamilton SA, Tong DC (2003) Efficacy of IV tissue plasminogen activator in acute stroke: does stroke subtype really matter? Neurology 61(1):71–75
    • (2003) Neurology , vol.61 , Issue.1 , pp. 71-75
    • Hsia, A.W.1    Sachdev, H.S.2    Tomlinson, J.3    Hamilton, S.A.4    Tong, D.C.5
  • 30
    • 34547155270 scopus 로고    scopus 로고
    • The Barthel Index and modified Rankin Scale as prognostic tools for long-term outcomes after stroke: a qualitative review of the literature
    • PID: 17559756
    • Huybrechts KF, Caro JJ (2007) The Barthel Index and modified Rankin Scale as prognostic tools for long-term outcomes after stroke: a qualitative review of the literature. Curr Med Res Opin 23(7):1627–1636. doi:10.1185/030079907X210444
    • (2007) Curr Med Res Opin , vol.23 , Issue.7 , pp. 1627-1636
    • Huybrechts, K.F.1    Caro, J.J.2
  • 33
    • 79957929098 scopus 로고    scopus 로고
    • Thrombotic distal middle cerebral artery occlusion produced by topical FeCl(3) application: a novel model suitable for intravital microscopy and thrombolysis studies
    • COI: 1:CAS:528:DC%2BC3MXmvFyjtL4%3D
    • Karatas H, Erdener SE, Gursoy-Ozdemir Y, Gurer G, Soylemezoglu F, Dunn AK, Dalkara T (2011) Thrombotic distal middle cerebral artery occlusion produced by topical FeCl(3) application: a novel model suitable for intravital microscopy and thrombolysis studies. J Cereb Blood Flow Metab Off J Int Soc Cereb Blood Flow Metab 31(6):1452–1460. doi:10.1038/jcbfm.2011.8
    • (2011) J Cereb Blood Flow Metab Off J Int Soc Cereb Blood Flow Metab , vol.31 , Issue.6 , pp. 1452-1460
    • Karatas, H.1    Erdener, S.E.2    Gursoy-Ozdemir, Y.3    Gurer, G.4    Soylemezoglu, F.5    Dunn, A.K.6    Dalkara, T.7
  • 35
    • 0029844999 scopus 로고    scopus 로고
    • Anesthetics and cerebroprotection: experimental aspects
    • COI: 1:CAS:528:DyaK2sXivVCisQ%3D%3D, PID: 8956065
    • Kirsch JR, Traystman RJ, Hurn PD (1996) Anesthetics and cerebroprotection: experimental aspects. Int Anesthesiol Clin 34(4):73–93
    • (1996) Int Anesthesiol Clin , vol.34 , Issue.4 , pp. 73-93
    • Kirsch, J.R.1    Traystman, R.J.2    Hurn, P.D.3
  • 36
    • 33748669435 scopus 로고    scopus 로고
    • Brain protection by anesthetic agents
    • PID: 16960478
    • Koerner IP, Brambrink AM (2006) Brain protection by anesthetic agents. Curr Opin Anaesthesiol 19(5):481–486
    • (2006) Curr Opin Anaesthesiol , vol.19 , Issue.5 , pp. 481-486
    • Koerner, I.P.1    Brambrink, A.M.2
  • 38
    • 79958253393 scopus 로고    scopus 로고
    • RAPID automated patient selection for reperfusion therapy: a pooled analysis of the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) and the Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution (DEFUSE) Study
    • Lansberg MG, Lee J, Christensen S, Straka M, De Silva DA, Mlynash M, Campbell BC, Bammer R, Olivot JM, Desmond P, Davis SM, Donnan GA, Albers GW (2011) RAPID automated patient selection for reperfusion therapy: a pooled analysis of the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET) and the Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution (DEFUSE) Study. Stroke J Cereb Circ 42(6):1608–1614. doi:10.1161/STROKEAHA.110.609008
    • (2011) Stroke J Cereb Circ , vol.42 , Issue.6 , pp. 1608-1614
    • Lansberg, M.G.1    Lee, J.2    Christensen, S.3    Straka, M.4    De Silva, D.A.5    Mlynash, M.6    Campbell, B.C.7    Bammer, R.8    Olivot, J.M.9    Desmond, P.10    Davis, S.M.11    Donnan, G.A.12    Albers, G.W.13
  • 40
    • 70249144995 scopus 로고    scopus 로고
    • Effect of internal carotid artery reperfusion in combination with Tenecteplase on clinical scores and hemorrhage in a rabbit embolic stroke model
    • COI: 1:CAS:528:DC%2BD1MXhtFGlur3E, PID: 19643097
    • Lapchak PA (2009) Effect of internal carotid artery reperfusion in combination with Tenecteplase on clinical scores and hemorrhage in a rabbit embolic stroke model. Brain Res 1294:211–217. doi:10.1016/j.brainres.2009.07.058
    • (2009) Brain Res , vol.1294 , pp. 211-217
    • Lapchak, P.A.1
  • 41
    • 77953639695 scopus 로고    scopus 로고
    • Translational stroke research using a rabbit embolic stroke model: a correlative analysis hypothesis for novel therapy development
    • PID: 20539748
    • Lapchak PA (2010) Translational stroke research using a rabbit embolic stroke model: a correlative analysis hypothesis for novel therapy development. Transl Stroke Res 1(2):96–107. doi:10.1007/s12975-010-0018-4
    • (2010) Transl Stroke Res , vol.1 , Issue.2 , pp. 96-107
    • Lapchak, P.A.1
  • 42
    • 0036712353 scopus 로고    scopus 로고
    • Microplasmin: a novel thrombolytic that improves behavioral outcome after embolic strokes in rabbits
    • COI: 1:CAS:528:DC%2BD38XntVKku70%3D
    • Lapchak PA, Araujo DM, Pakola S, Song D, Wei J, Zivin JA (2002a) Microplasmin: a novel thrombolytic that improves behavioral outcome after embolic strokes in rabbits. Stroke J Cereb Circ 33(9):2279–2284
    • (2002) Stroke J Cereb Circ , vol.33 , Issue.9 , pp. 2279-2284
    • Lapchak, P.A.1    Araujo, D.M.2    Pakola, S.3    Song, D.4    Wei, J.5    Zivin, J.A.6
  • 43
    • 0036098259 scopus 로고    scopus 로고
    • Neuroprotective effects of the spin trap agent disodium-[(tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (generic NXY-059) in a rabbit small clot embolic stroke model: combination studies with the thrombolytic tissue plasminogen activator
    • COI: 1:CAS:528:DC%2BD38Xkt1SmsLg%3D
    • Lapchak PA, Araujo DM, Song D, Wei J, Zivin JA (2002b) Neuroprotective effects of the spin trap agent disodium-[(tert-butylimino)methyl]benzene-1,3-disulfonate N-oxide (generic NXY-059) in a rabbit small clot embolic stroke model: combination studies with the thrombolytic tissue plasminogen activator. Stroke J Cereb Circ 33(5):1411–1415
    • (2002) Stroke J Cereb Circ , vol.33 , Issue.5 , pp. 1411-1415
    • Lapchak, P.A.1    Araujo, D.M.2    Song, D.3    Wei, J.4    Zivin, J.A.5
  • 44
    • 84877134982 scopus 로고    scopus 로고
    • RIGOR Guidelines: Escalating STAIR and STEPS for effective translational research
    • PID: 23658596
    • Lapchak PA, Zhang JH, Noble-Haeusslein LJ (2013) RIGOR Guidelines: Escalating STAIR and STEPS for effective translational research. Transl Stroke Res 4(3):279–285. doi:10.1007/s12975-012-0209-2
    • (2013) Transl Stroke Res , vol.4 , Issue.3 , pp. 279-285
    • Lapchak, P.A.1    Zhang, J.H.2    Noble-Haeusslein, L.J.3
  • 45
    • 84857715780 scopus 로고    scopus 로고
    • The impact of pharmacogenomics research on drug development
    • COI: 1:CAS:528:DC%2BC38Xnt1Ggsbc%3D, PID: 22214937
    • Liou SY, Stringer F, Hirayama M (2012) The impact of pharmacogenomics research on drug development. Drug Metab Pharmacokinet 27(1):2–8
    • (2012) Drug Metab Pharmacokinet , vol.27 , Issue.1 , pp. 2-8
    • Liou, S.Y.1    Stringer, F.2    Hirayama, M.3
  • 46
    • 84888289689 scopus 로고    scopus 로고
    • Antiplatelet loading improves behavioral outcome in a rabbit model of stroke
    • COI: 1:CAS:528:DC%2BC3sXhvV2gs7fE
    • Meyer DM, Compton P, Eastwood JA, Gylys K, Zivin JA (2013) Antiplatelet loading improves behavioral outcome in a rabbit model of stroke. Stroke J Cereb Circ 44(11):3246–3248. doi:10.1161/STROKEAHA.113.002565
    • (2013) Stroke J Cereb Circ , vol.44 , Issue.11 , pp. 3246-3248
    • Meyer, D.M.1    Compton, P.2    Eastwood, J.A.3    Gylys, K.4    Zivin, J.A.5
  • 49
    • 84881315517 scopus 로고    scopus 로고
    • Validating therapeutic targets through human genetics
    • COI: 1:CAS:528:DC%2BC3sXhtFalsLrI, PID: 23868113
    • Plenge RM, Scolnick EM, Altshuler D (2013) Validating therapeutic targets through human genetics. Nat Rev Drug Discov 12(8):581–594. doi:10.1038/nrd4051
    • (2013) Nat Rev Drug Discov , vol.12 , Issue.8 , pp. 581-594
    • Plenge, R.M.1    Scolnick, E.M.2    Altshuler, D.3
  • 50
    • 70349686724 scopus 로고    scopus 로고
    • Reliability of the modified Rankin Scale: a systematic review
    • Quinn TJ, Dawson J, Walters MR, Lees KR (2009) Reliability of the modified Rankin Scale: a systematic review. Stroke J Cereb Circ 40(10):3393–3395. doi:10.1161/STROKEAHA.109.557256
    • (2009) Stroke J Cereb Circ , vol.40 , Issue.10 , pp. 3393-3395
    • Quinn, T.J.1    Dawson, J.2    Walters, M.R.3    Lees, K.R.4
  • 51
    • 40449086665 scopus 로고    scopus 로고
    • Dose translation from animal to human studies revisited
    • COI: 1:CAS:528:DC%2BD1cXjtVaqsrY%3D
    • Reagan-Shaw S, Nihal M, Ahmad N (2008) Dose translation from animal to human studies revisited. FASEB J Off Publ Fed Am Soc Exp Biol 22(3):659–661. doi:10.1096/fj.07-9574LSF
    • (2008) FASEB J Off Publ Fed Am Soc Exp Biol , vol.22 , Issue.3 , pp. 659-661
    • Reagan-Shaw, S.1    Nihal, M.2    Ahmad, N.3
  • 53
    • 33751067468 scopus 로고    scopus 로고
    • Small animal models of cardiovascular disease: tools for the study of the roles of metabolic syndrome, dyslipidemia, and atherosclerosis
    • COI: 1:CAS:528:DC%2BD28Xht1Cgsb3L
    • Russell JC, Proctor SD (2006) Small animal models of cardiovascular disease: tools for the study of the roles of metabolic syndrome, dyslipidemia, and atherosclerosis. Cardiovasc Pathol Off J Soc Cardiovasc Pathol 15(6):318–330. doi:10.1016/j.carpath.2006.09.001
    • (2006) Cardiovasc Pathol Off J Soc Cardiovasc Pathol , vol.15 , Issue.6 , pp. 318-330
    • Russell, J.C.1    Proctor, S.D.2
  • 54
    • 67650079318 scopus 로고    scopus 로고
    • Stroke Therapy Academic Industry Roundtable (STAIR) recommendations for extended window acute stroke therapy trials
    • Saver JL, Albers GW, Dunn B, Johnston KC, Fisher M, Consortium SV (2009) Stroke Therapy Academic Industry Roundtable (STAIR) recommendations for extended window acute stroke therapy trials. Stroke J Cereb Circ 40(7):2594–2600. doi:10.1161/STROKEAHA.109.552554
    • (2009) Stroke J Cereb Circ , vol.40 , Issue.7 , pp. 2594-2600
    • Saver, J.L.1    Albers, G.W.2    Dunn, B.3    Johnston, K.C.4    Fisher, M.5    Consortium, S.V.6
  • 55
    • 77953234766 scopus 로고    scopus 로고
    • Animal models of focal brain ischemia
    • PID: 20150985
    • Sicard KM, Fisher M (2009) Animal models of focal brain ischemia. Exp Transl Stroke Med 1:7–7
    • (2009) Exp Transl Stroke Med , vol.1 , pp. 7
    • Sicard, K.M.1    Fisher, M.2
  • 56
    • 33644896517 scopus 로고    scopus 로고
    • Preclinical pharmacokinetics: an approach towards safer and efficacious drugs
    • COI: 1:CAS:528:DC%2BD28Xht1Oms70%3D
    • Singh SS (2006) Preclinical pharmacokinetics: an approach towards safer and efficacious drugs. Current Drug Metab 7(2):165–182
    • (2006) Current Drug Metab , vol.7 , Issue.2 , pp. 165-182
    • Singh, S.S.1
  • 58
    • 0034943173 scopus 로고    scopus 로고
    • Recommendations for clinical trial evaluation of acute stroke therapies
    • Stroke Therapy Academic Industry R, II (2001) Recommendations for clinical trial evaluation of acute stroke therapies. Stroke J Cereb Circ 32(7):1598–1606
    • (2001) Stroke J Cereb Circ , vol.32 , Issue.7 , pp. 1598-1606
    • Stroke Therapy Academic Industry R,, I.I.1
  • 59
    • 0031444569 scopus 로고    scopus 로고
    • Reproducibility and reliability of middle cerebral artery occlusion using a silicone-coated suture (Koizumi) in rats
    • COI: 1:STN:280:DyaK1c7hsFGjtA%3D%3D, PID: 9455971
    • Takano K, Tatlisumak T, Bergmann AG, Gibson DG 3rd, Fisher M (1997) Reproducibility and reliability of middle cerebral artery occlusion using a silicone-coated suture (Koizumi) in rats. J Neurol Sci 153(1):8–11
    • (1997) J Neurol Sci , vol.153 , Issue.1 , pp. 8-11
    • Takano, K.1    Tatlisumak, T.2    Bergmann, A.G.3    Gibson, D.G.4    Fisher, M.5
  • 60
    • 0035205029 scopus 로고    scopus 로고
    • Blood genomic responses differ after stroke, seizures, hypoglycemia, and hypoxia: blood genomic fingerprints of disease
    • COI: 1:CAS:528:DC%2BD38Xhs1KnsA%3D%3D, PID: 11761467
    • Tang Y, Lu A, Aronow BJ, Sharp FR (2001) Blood genomic responses differ after stroke, seizures, hypoglycemia, and hypoxia: blood genomic fingerprints of disease. Ann Neurol 50(6):699–707
    • (2001) Ann Neurol , vol.50 , Issue.6 , pp. 699-707
    • Tang, Y.1    Lu, A.2    Aronow, B.J.3    Sharp, F.R.4
  • 63
    • 33846985962 scopus 로고    scopus 로고
    • Experimental models of thrombosis and atherosclerosis
    • PID: 17243266
    • Verbeuren TJ (2006) Experimental models of thrombosis and atherosclerosis. Therapie 61(5):379–387
    • (2006) Therapie , vol.61 , Issue.5 , pp. 379-387
    • Verbeuren, T.J.1
  • 64
    • 41149099184 scopus 로고    scopus 로고
    • Glutamate-induced c-Jun expression in neuronal PC12 cells: the effects of ketamine and propofol
    • PID: 18362774
    • Wang L, Jing W, Hang YN (2008) Glutamate-induced c-Jun expression in neuronal PC12 cells: the effects of ketamine and propofol. J Neurosurg Anesthesiol 20(2):124–130
    • (2008) J Neurosurg Anesthesiol , vol.20 , Issue.2 , pp. 124-130
    • Wang, L.1    Jing, W.2    Hang, Y.N.3
  • 65
    • 50049108859 scopus 로고    scopus 로고
    • What should be defined as good outcome in stroke trials; a modified Rankin score of 0–1 or 0–2?
    • COI: 1:STN:280:DC%2BD1crivVCmsw%3D%3D, PID: 18338195
    • Weisscher N, Vermeulen M, Roos YB, de Haan RJ (2008) What should be defined as good outcome in stroke trials; a modified Rankin score of 0–1 or 0–2? J Neurol 255(6):867–874. doi:10.1007/s00415-008-0796-8
    • (2008) J Neurol , vol.255 , Issue.6 , pp. 867-874
    • Weisscher, N.1    Vermeulen, M.2    Roos, Y.B.3    de Haan, R.J.4
  • 66
    • 3242656169 scopus 로고    scopus 로고
    • The laboratory rabbit: an animal model of atherosclerosis research
    • COI: 1:CAS:528:DC%2BD2cXotVyitLw%3D, PID: 15207035
    • Yanni AE (2004) The laboratory rabbit: an animal model of atherosclerosis research. Lab Anim 38(3):246–256. doi:10.3201/eid0905.020321
    • (2004) Lab Anim , vol.38 , Issue.3 , pp. 246-256
    • Yanni, A.E.1
  • 67
    • 84863470227 scopus 로고    scopus 로고
    • Standards and pitfalls of focal ischemia models in spontaneously hypertensive rats: with a systematic review of recent articles
    • PID: 22770528
    • Yao H, Nabika T (2012) Standards and pitfalls of focal ischemia models in spontaneously hypertensive rats: with a systematic review of recent articles. J Transl Med 10:139. doi:10.1186/1479-5876-10-139
    • (2012) J Transl Med , vol.10 , pp. 139
    • Yao, H.1    Nabika, T.2
  • 68
    • 77953778852 scopus 로고    scopus 로고
    • Establishment of a novel hemodynamic cerebral ischemia model of atherosclerotic rabbit
    • PID: 20508334
    • Zhang GY, Chen ZQ, Ling F, Li YJ, Wang Y, Gu BX (2010) Establishment of a novel hemodynamic cerebral ischemia model of atherosclerotic rabbit. Neurol India 58(2):191–194. doi:10.4103/0028-3886.63782
    • (2010) Neurol India , vol.58 , Issue.2 , pp. 191-194
    • Zhang, G.Y.1    Chen, Z.Q.2    Ling, F.3    Li, Y.J.4    Wang, Y.5    Gu, B.X.6
  • 69
    • 72149126888 scopus 로고    scopus 로고
    • The modified Rankin Scale in acute stroke has good inter-rater-reliability but questionable validity
    • PID: 20029188
    • Zhao H, Collier JM, Quah DM, Purvis T, Bernhardt J (2010) The modified Rankin Scale in acute stroke has good inter-rater-reliability but questionable validity. Cerebrovasc Dis 29(2):188–193. doi:10.1159/000267278
    • (2010) Cerebrovasc Dis , vol.29 , Issue.2 , pp. 188-193
    • Zhao, H.1    Collier, J.M.2    Quah, D.M.3    Purvis, T.4    Bernhardt, J.5
  • 70
    • 0022405261 scopus 로고
    • Tissue plasminogen activator reduces neurological damage after cerebral embolism
    • COI: 1:CAS:528:DyaL28XksFGitw%3D%3D, PID: 3934754
    • Zivin JA, Fisher M, DeGirolami U, Hemenway CC, Stashak JA (1985) Tissue plasminogen activator reduces neurological damage after cerebral embolism. Science 230(4731):1289–1292
    • (1985) Science , vol.230 , Issue.4731 , pp. 1289-1292
    • Zivin, J.A.1    Fisher, M.2    DeGirolami, U.3    Hemenway, C.C.4    Stashak, J.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.