Concomitant manipulation of murine NMDA- and AMPA-receptors to produce pro-cognitive drug effects in mice

European Neuropsychopharmacology

Volumn 24, Issue 2, 2014, Pages 309-320

  Vignisse, Julie ^a,b   Steinbusch, Harry W M ^a   Grigoriev, Vladimir ^c   Bolkunov, Alexei ^c   Proshin, Alexey ^c   Bettendorff, Lucien ^b   Bachurin, Sergey ^c   Strekalova, Tatyana ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c INSTITUTE OF PHYSIOLOGICALLY ACTIVE COMPOUNDS   (Russian Federation)

Author keywords

Low affinity NMDA receptor blockade; Mouse; Multi target mechanism; Positive modulation of AMPA receptor

Indexed keywords

AMPA RECEPTOR; GLUTAMATE RECEPTOR; IPAC 1; IPAC 2; IPAC 3; IPAC 4; IPAC 5; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; QXX; SULFAMIDE DERIVATIVE; THIOUREA DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONDITIONING; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; IC 50; LATENT PERIOD; LEARNING; LIGHT-DARK TEST; MALE; MEMORY; MOLECULE; MOUSE; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NONHUMAN; PRIORITY JOURNAL; PURKINJE CELL; RAT; STEP-DOWN PASSIVE AVOIDANCE; TASK PERFORMANCE;

LOW-AFFINITY NMDA RECEPTOR BLOCKADE; MOUSE; MULTI-TARGET MECHANISM; POSITIVE MODULATION OF AMPA RECEPTOR;

ALLYL COMPOUNDS; ANIMALS; ANXIETY; AVOIDANCE LEARNING; BRAIN; CONDITIONING (PSYCHOLOGY); DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; EXTINCTION, PSYCHOLOGICAL; FEAR; LEARNING; MALE; MEMANTINE; MEMORY; MENTAL RECALL; MICE; MICE, INBRED C57BL; RATS; RECEPTORS, AMPA; RECEPTORS, N-METHYL-D-ASPARTATE; THIOUREA;

EID: 84893682532     PISSN: 0924977X     EISSN: 18737862     Source Type: Journal    
DOI: 10.1016/j.euroneuro.2013.06.010     Document Type: Article

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