Anhedonic-like traits and lack of affective deficits in 18-month-old C57BL/6 mice: Implications for modeling elderly depression

Experimental Gerontology

Volumn 47, Issue 8, 2012, Pages 552-564

  Malatynska, Ewa ^a   Steinbusch, Harry W M ^b   Redkozubova, Olga ^c   Bolkunov, Alexei ^c   Kubatiev, Aslan ^d   Yeritsyan, Naira B ^e   Vignisse, Julie ^b   Bachurin, Sergei ^c   Strekalova, Tatyana ^b  

^a ELI LILLY AND COMPANY   (United States)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c INSTITUTE OF PHYSIOLOGICALLY ACTIVE COMPOUNDS   (Russian Federation)

^d INSTITUTE OF GENERAL PATHOLOGY AND PATHOPHYSIOLOGY   (Russian Federation)

^e LEIBNIZ INSTITUTE FOR NEUROBIOLOGY   (Germany)

Author keywords

Anhedonia; Behavioral despair; Dimebon; Elderly depression; Imipramine; Mouse; Sucrose test

Indexed keywords

DIMEBON; IMIPRAMINE;

AFFECT; AGE DISTRIBUTION; AGING; ANHEDONIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; CONTROLLED STUDY; DEPRESSION; EXPLORATORY BEHAVIOR; FLUID INTAKE; FORCED SWIMMING TEST; GROOMING; IMMOBILIZATION; LOCOMOTION; MOTOR PERFORMANCE; MOUSE; NEOPHOBIA; NONHUMAN; PRIORITY JOURNAL; SUGAR INTAKE; TASTE;

AGING; ANHEDONIA; ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; ANXIETY; BEHAVIOR, ANIMAL; DEPRESSIVE DISORDER, MAJOR; DISEASE MODELS, ANIMAL; DRINKING BEHAVIOR; EXPLORATORY BEHAVIOR; GROOMING; HINDLIMB SUSPENSION; IMIPRAMINE; INDOLES; MALE; MICE; MICE, INBRED C57BL; MOOD DISORDERS; MOTOR ACTIVITY; SUCROSE; SWIMMING;

ANIMALIA; MUS; RODENTIA;

EID: 84863103763     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2012.04.010     Document Type: Article

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