Reconsidering sufficient and optimal test design in acute toxicity testing

Ecotoxicology

Volumn 23, Issue 1, 2014, Pages 38-44

  Jager, Tjalling ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Experimental design; GUTS; LC50; Survival; TKTD modelling

Indexed keywords

DICHLOROBUTENE; DIMPYLATE; NAPHTHALENE; UNCLASSIFIED DRUG; 3,4-DICHLORO-1-BUTENE; CHLORINATED HYDROCARBON; INSECTICIDE; NAPHTHALENE DERIVATIVE; WATER POLLUTANT;

CONCENTRATION (COMPOSITION); DOSE-RESPONSE RELATIONSHIP; ECOTOXICOLOGY; ENVIRONMENTAL RISK; EXPERIMENTAL DESIGN; HYPOTHESIS TESTING; MORTALITY; OPTIMIZATION; REGRESSION ANALYSIS; RISK ASSESSMENT; TOXICITY TEST;

ACUTE TOXICITY; ARTICLE; CLINICAL PROTOCOL; CONCENTRATION (PARAMETERS); CONFIDENCE INTERVAL; CONTROLLED STUDY; DOSE RESPONSE; DYNAMICS; ECOTOXICOLOGY; ENVIRONMENTAL IMPACT ASSESSMENT; GAMMARUS PULEX; LC 50; MORTALITY; NONHUMAN; OBSERVATIONAL STUDY; PIMEPHALES PROMELAS; PRIORITY JOURNAL; REGRESSION ANALYSIS; STATISTICAL ANALYSIS; TOXICITY TESTING; TOXICOKINETICS; AMPHIPODA; ANIMAL; BIOLOGICAL MODEL; CYPRINIDAE; DRUG EFFECTS; EVALUATION STUDY; LD50; METABOLISM; PROCEDURES; RISK ASSESSMENT; TOXICITY; WATER POLLUTANT;

ANIMALIA;

AMPHIPODA; ANIMALS; CYPRINIDAE; DIAZINON; DOSE-RESPONSE RELATIONSHIP, DRUG; HYDROCARBONS, CHLORINATED; INSECTICIDES; LETHAL DOSE 50; MODELS, BIOLOGICAL; NAPHTHALENES; RISK ASSESSMENT; TOXICITY TESTS, ACUTE; WATER POLLUTANTS, CHEMICAL;

EID: 84893666840     PISSN: 09639292     EISSN: 15733017     Source Type: Journal    
DOI: 10.1007/s10646-013-1149-7     Document Type: Article

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