IFNγ inhibits Th17 differentiation and function via Tbet-dependent and Tbet-independent mechanisms

Journal of Neuroimmunology

Volumn 267, Issue 1-2, 2014, Pages 20-27

  Yeh, Wen I ^a   McWilliams, Ian L ^a   Harrington, Laurie E ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

CD4 T cell; Experimental autoimmune encephalomyelitis; IFN ; IL 17A; Tbet

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 17F; PROTEIN ROR GAMMA T; STAT1 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR T BET; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CELL LINEAGE; CONTROLLED STUDY; CYTOKINE PRODUCTION; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TH17 CELL;

CD4 T CELL; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; IFNΓ; IL-17A; TBET;

ANIMALS; ANTIGENS, CD4; ANTIGENS, CD45; CELL DIFFERENTIATION; CELL POLARITY; CENTRAL NERVOUS SYSTEM; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; INTERLEUKIN-12 SUBUNIT P40; INTERLEUKIN-17; INTERLEUKINS; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, TRANSGENIC; NUCLEAR RECEPTOR SUBFAMILY 1, GROUP F, MEMBER 3; STAT1 TRANSCRIPTION FACTOR; T-BOX DOMAIN PROTEINS; TH17 CELLS;

EID: 84893664708     PISSN: 01655728     EISSN: 18728421     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2013.12.001     Document Type: Article

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