Facilitated brain delivery of poly (ethylene glycol)-poly (lactic acid) nanoparticles by microbubble-enhanced unfocused ultrasound

Biomaterials

Volumn 35, Issue 10, 2014, Pages 3384-3395

  Yao, Lei ^a   Song, Qingxiang ^a   Bai, Wenkun ^b   Zhang, Jizhen ^b   Miao, Deyu ^c   Jiang, Mengyin ^c   Wang, Yu ^b   Shen, Zhiyong ^b   Hu, Quanyin ^c   Gu, Xiao ^a   Huang, Meng ^a   Zheng, Gang ^d   Gao, Xiaoling ^a   Hu, Bing ^b   Chen, Jun ^c   Chen, Hongzhuan ^a  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SHANGHAI JIAO TONG UNIVERSITY AFFILIATED SIXTH PEOPLE S HOSPITAL   (China)

^c FUDAN UNIVERSITY   (China)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

Brain delivery; Microbubble; Nanoparticles; Unfocused ultrasound

Indexed keywords

ALZHEIMER'S DISEASE; BLOOD-BRAIN BARRIER; BRAIN DELIVERY; FLEXIBLE PLATFORMS; MECHANICAL INDEXES; MECHANICAL STRETCHING; MICRO-BUBBLE; TRANSMISSION ELECTRON;

BLOOD; DAMAGE DETECTION; DIAGNOSIS; DISEASE CONTROL; DRUG DELIVERY; LACTIC ACID; POLYETHYLENE GLYCOLS; TRANSMISSION ELECTRON MICROSCOPY; ULTRASONIC APPLICATIONS; ULTRASONICS;

NANOPARTICLES;

AMYLOID BETA PROTEIN ANTIBODY; AMYLOID BETA PROTEIN ANTIBODY 6E10; MACROGOL; POLYLACTIC ACID; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOMECHANICS; BLOOD VESSEL WALL; BRAIN; BRAIN PARENCHYMA; CONFOCAL MICROSCOPY; CONTROLLED STUDY; IN VITRO STUDY; IN VIVO STUDY; MICROBUBBLE ENHANCED UNFOCUSED ULTRASOUND; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; QUANTITATIVE ANALYSIS; RADIATION DOSE; STAINING; TRANSCYTOSIS; TRANSMISSION ELECTRON MICROSCOPY; ULTRASOUND THERAPY;

BRAIN DELIVERY; MICROBUBBLE; NANOPARTICLES; UNFOCUSED ULTRASOUND;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; COUMARINS; FLUORESCENT DYES; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; POLYETHYLENE GLYCOLS; ULTRASONICS;

EID: 84893636634     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.12.043     Document Type: Article

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