메뉴 건너뛰기




Volumn 44, Issue 2, 2014, Pages 469-479

PD-1 modulates steady-state and infection-induced IL-10 production in vivo

Author keywords

IL 10; PD 1; Toxoplasma gondii

Indexed keywords

CD11B ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR; INTERLEUKIN 12; INTERLEUKIN 12P40; INTERLEUKIN 12P70; PROGRAMMED DEATH 1 LIGAND 1;

EID: 84893615972     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201343658     Document Type: Article
Times cited : (18)

References (61)
  • 1
    • 80051915459 scopus 로고    scopus 로고
    • CD8α+ dendritic cells are the critical source of interleukin-12 that controls acute infection by Toxoplasma gondii tachyzoites
    • Mashayekhi, M., Sandau, M. M., Dunay, I. R., Frickel, E. M., Khan, A., Goldszmid, R. S., Sher, A. et al., CD8α+ dendritic cells are the critical source of interleukin-12 that controls acute infection by Toxoplasma gondii tachyzoites. Immunity 2011. 35: 249-259.
    • (2011) Immunity , vol.35 , pp. 249-259
    • Mashayekhi, M.1    Sandau, M.M.2    Dunay, I.R.3    Frickel, E.M.4    Khan, A.5    Goldszmid, R.S.6    Sher, A.7
  • 2
    • 0034662258 scopus 로고    scopus 로고
    • Cutting edge: IL-12 is required for the maintenance of IFN-γ production in T cells mediating chronic resistance to the intracellular pathogen, Toxoplasma gondii
    • Yap, G., Pesin, M. and Sher, A., Cutting edge: IL-12 is required for the maintenance of IFN-γ production in T cells mediating chronic resistance to the intracellular pathogen, Toxoplasma gondii. J. Immunol. 2000. 165: 628-631.
    • (2000) J. Immunol. , vol.165 , pp. 628-631
    • Yap, G.1    Pesin, M.2    Sher, A.3
  • 3
    • 0030294163 scopus 로고    scopus 로고
    • In the absence of endogenous IFN-gamma, mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection
    • Scharton-Kersten, T., Wynn, T., Denkers, E., Bala, S., Hieny, S., Gazzinelli, R. and Sher, A., In the absence of endogenous IFN-gamma, mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection. J. Immunol. 1996. 157: 4045-4054.
    • (1996) J. Immunol. , vol.157 , pp. 4045-4054
    • Scharton-Kersten, T.1    Wynn, T.2    Denkers, E.3    Bala, S.4    Hieny, S.5    Gazzinelli, R.6    Sher, A.7
  • 4
    • 33745327590 scopus 로고    scopus 로고
    • Cutting edge: dendritic cells are essential for in vivo IL-12 production and development of resistance against Toxoplasma gondii infection in mice
    • Liu, C., Fan, Y., Dias, A., Esper, L., Corn, R., Bafica, A., Machado, F. et al., Cutting edge: dendritic cells are essential for in vivo IL-12 production and development of resistance against Toxoplasma gondii infection in mice. J. Immunol. 2006. 177: 31-35.
    • (2006) J. Immunol. , vol.177 , pp. 31-35
    • Liu, C.1    Fan, Y.2    Dias, A.3    Esper, L.4    Corn, R.5    Bafica, A.6    Machado, F.7
  • 5
    • 0033567090 scopus 로고    scopus 로고
    • Murine neutrophil stimulation by Toxoplama gondii antigen drives high level production of IFN-gamma-independent IL-12
    • Bliss, S., Zhang, Y. and Denkers, E., Murine neutrophil stimulation by Toxoplama gondii antigen drives high level production of IFN-gamma-independent IL-12. J. Immunol. 1999. 163: 2081-2088.
    • (1999) J. Immunol. , vol.163 , pp. 2081-2088
    • Bliss, S.1    Zhang, Y.2    Denkers, E.3
  • 6
    • 0000060327 scopus 로고    scopus 로고
    • In vivo microbial stimulation induces rapid CD40 ligand-indepedent production of interleukin 12 by dendritic cells and their redistribution to T cell areas
    • Reis e Sousa, C., Hieny, S., Scharton-Kersten, T., Jankovic, D., Charest, H., Germain, R. N. and Sher, A., In vivo microbial stimulation induces rapid CD40 ligand-indepedent production of interleukin 12 by dendritic cells and their redistribution to T cell areas. J. Exp. Med. 1997. 186: 1819-1829.
    • (1997) J. Exp. Med. , vol.186 , pp. 1819-1829
    • Reis e Sousa, C.1    Hieny, S.2    Scharton-Kersten, T.3    Jankovic, D.4    Charest, H.5    Germain, R.N.6    Sher, A.7
  • 7
    • 0029959459 scopus 로고    scopus 로고
    • In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha
    • Gazzinelli, R., Wysocka, M., Hieny, S., Scharton-Kersten, T., Cheever, A., Kuhn, R., Muller, W. et al., In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha. J. Immunol. 1996. 157: 798-805.
    • (1996) J. Immunol. , vol.157 , pp. 798-805
    • Gazzinelli, R.1    Wysocka, M.2    Hieny, S.3    Scharton-Kersten, T.4    Cheever, A.5    Kuhn, R.6    Muller, W.7
  • 8
    • 0027939611 scopus 로고
    • Parasite-induced IL-12 stimulates early IFN-gamma synthesis and resistance during acute infection with Toxoplasma gondii
    • Gazzinelli, R., Wysocka, M., Hayashi, S., Denkers, E., Hieny, S., Casper, P., Trinchieri, G. et al., Parasite-induced IL-12 stimulates early IFN-gamma synthesis and resistance during acute infection with Toxoplasma gondii. J. Immunol. 1994. 153: 2533-2543.
    • (1994) J. Immunol. , vol.153 , pp. 2533-2543
    • Gazzinelli, R.1    Wysocka, M.2    Hayashi, S.3    Denkers, E.4    Hieny, S.5    Casper, P.6    Trinchieri, G.7
  • 9
    • 1842417179 scopus 로고    scopus 로고
    • Role of interleukin-10 in regulation of T-cell-dependent and T-cell-independent mechanisms of resistance to Toxoplasma gondii
    • Neyer, L., Gruning, G., Fort, M., Remington, J., Rennick, D. and Hunter, C., Role of interleukin-10 in regulation of T-cell-dependent and T-cell-independent mechanisms of resistance to Toxoplasma gondii. Infect Immun. 1997. 65: 1675-1682.
    • (1997) Infect Immun. , vol.65 , pp. 1675-1682
    • Neyer, L.1    Gruning, G.2    Fort, M.3    Remington, J.4    Rennick, D.5    Hunter, C.6
  • 10
    • 0037020861 scopus 로고    scopus 로고
    • Parasite-induced lipoxin A4 is an endogenous regulator of IL-12 production and immunopathology in Toxoplasma gondii infection
    • Aliberti, J., Serhan, C. and Sher, A., Parasite-induced lipoxin A4 is an endogenous regulator of IL-12 production and immunopathology in Toxoplasma gondii infection. J. Exp. Med. 2002. 196: 1253-1262.
    • (2002) J. Exp. Med. , vol.196 , pp. 1253-1262
    • Aliberti, J.1    Serhan, C.2    Sher, A.3
  • 11
    • 0031091746 scopus 로고    scopus 로고
    • The role of the CD28/B7 interaction in the regulation of NK cell responses during infection with Toxoplasma gondii
    • Hunter, C., Ellis-Neyer, L., Gabriel, K., Kennedy, M., Grabstein, K., Linsley, P. and Remington, J., The role of the CD28/B7 interaction in the regulation of NK cell responses during infection with Toxoplasma gondii. J. Immunol. 1997. 158: 2285-2293.
    • (1997) J. Immunol. , vol.158 , pp. 2285-2293
    • Hunter, C.1    Ellis-Neyer, L.2    Gabriel, K.3    Kennedy, M.4    Grabstein, K.5    Linsley, P.6    Remington, J.7
  • 12
    • 1842581712 scopus 로고    scopus 로고
    • CTLA-4 blockage increases resistance to infection with the intracellular protozoan Trypanosoma cruzi
    • Martins, G., Tadokoro, C., Silva, R., Silva, J. and Rizzo, L., CTLA-4 blockage increases resistance to infection with the intracellular protozoan Trypanosoma cruzi. J. Immunol. 2004. 172: 4893-4901.
    • (2004) J. Immunol. , vol.172 , pp. 4893-4901
    • Martins, G.1    Tadokoro, C.2    Silva, R.3    Silva, J.4    Rizzo, L.5
  • 13
    • 0032532640 scopus 로고    scopus 로고
    • Blockade of CTLA-4 enhances host resistance to the intracellular pathogen, Leishmania donovani
    • Murphy, M., Cotterell, S., Gorak, P., Engwerda, C. and Kaye, P., Blockade of CTLA-4 enhances host resistance to the intracellular pathogen, Leishmania donovani. J. Immunol. 1998. 161: 4153-4160.
    • (1998) J. Immunol. , vol.161 , pp. 4153-4160
    • Murphy, M.1    Cotterell, S.2    Gorak, P.3    Engwerda, C.4    Kaye, P.5
  • 14
    • 68249162080 scopus 로고    scopus 로고
    • Cytotoxic T-lymphocyte antigen 4 blockade augments the T-cell response primed by attenuated Listeria monocytogenes resulting in more rapid clearance of virulent bacterial challenge
    • Rowe, J., Johanns, T., Ertelt, J., Lai, J. and Way, S., Cytotoxic T-lymphocyte antigen 4 blockade augments the T-cell response primed by attenuated Listeria monocytogenes resulting in more rapid clearance of virulent bacterial challenge. Immunology 2009. 128: e471-e478.
    • (2009) Immunology , vol.128
    • Rowe, J.1    Johanns, T.2    Ertelt, J.3    Lai, J.4    Way, S.5
  • 15
    • 34247884612 scopus 로고    scopus 로고
    • The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection
    • Sharpe, A. H., Wherry, E. J., Ahmed, R. and Freeman, G. J., The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection. Nat. Immunol. 2007. 8: 239-245.
    • (2007) Nat. Immunol. , vol.8 , pp. 239-245
    • Sharpe, A.H.1    Wherry, E.J.2    Ahmed, R.3    Freeman, G.J.4
  • 16
    • 67651099087 scopus 로고    scopus 로고
    • PD-1 on dendritic cells impedes innate immunity against bacterial infection
    • Yao, S., Wang, S., Zhu, Y., Luo, L., Zhu, G., Flies, S., Xu, H. et al., PD-1 on dendritic cells impedes innate immunity against bacterial infection. Blood 2009. 113: 5811-5818.
    • (2009) Blood , vol.113 , pp. 5811-5818
    • Yao, S.1    Wang, S.2    Zhu, Y.3    Luo, L.4    Zhu, G.5    Flies, S.6    Xu, H.7
  • 17
    • 65549084772 scopus 로고    scopus 로고
    • PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis
    • Huang, X., Venet, F., Wang, Y., Lepape, A., Yuan, Z., Chen, Y., Swan, R. et al., PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis. PNAS 2009. 106: 6308-6308.
    • (2009) PNAS , vol.106 , pp. 6308-6308
    • Huang, X.1    Venet, F.2    Wang, Y.3    Lepape, A.4    Yuan, Z.5    Chen, Y.6    Swan, R.7
  • 18
    • 44449142522 scopus 로고    scopus 로고
    • Dendritic cell programming by cytomegalovirus stunts naive T cell responses via the PD-L1/PD-1 pathway
    • Benedict, C., Loewendorf, A., Garcia, Z., Blazar, B. and Janssen, E., Dendritic cell programming by cytomegalovirus stunts naive T cell responses via the PD-L1/PD-1 pathway. J. Immunol. 2008. 180: 4836-4847.
    • (2008) J. Immunol. , vol.180 , pp. 4836-4847
    • Benedict, C.1    Loewendorf, A.2    Garcia, Z.3    Blazar, B.4    Janssen, E.5
  • 20
    • 77955636377 scopus 로고    scopus 로고
    • Programmed death-1 (PD-1)-deficient mice are extraordinarily sensitive to tuberculosis
    • Lazar-Molnar, E., Chen, B., Sweeney, K., Wang, E., Liu, W., Lin, J., Porcelli, S. et al., Programmed death-1 (PD-1)-deficient mice are extraordinarily sensitive to tuberculosis. PNAS 2010. 107: 13402-13407.
    • (2010) PNAS , vol.107 , pp. 13402-13407
    • Lazar-Molnar, E.1    Chen, B.2    Sweeney, K.3    Wang, E.4    Liu, W.5    Lin, J.6    Porcelli, S.7
  • 21
    • 79251578015 scopus 로고    scopus 로고
    • CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition
    • Barber, D., Mayer-Barber, K., Feng, C., Sharpe, A. and Sher, A., CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition. J. Immunol. 2011. 186: 1598-1607.
    • (2011) J. Immunol. , vol.186 , pp. 1598-1607
    • Barber, D.1    Mayer-Barber, K.2    Feng, C.3    Sharpe, A.4    Sher, A.5
  • 23
    • 0037815272 scopus 로고    scopus 로고
    • PD-1 inhibits antiviral immunity at the effector phase in the liver
    • Iwai, Y., Terawaki, S., Ikegawa, M., Okazaki, T. and Honjo, T., PD-1 inhibits antiviral immunity at the effector phase in the liver. J. Exp. Med. 2003. 198: 39-50.
    • (2003) J. Exp. Med. , vol.198 , pp. 39-50
    • Iwai, Y.1    Terawaki, S.2    Ikegawa, M.3    Okazaki, T.4    Honjo, T.5
  • 24
    • 84863007648 scopus 로고    scopus 로고
    • NK cell-derived interferon-γ orchestrates cellular dynamics and the differentiation of monocytes into dendritic cells at the site of infection
    • Goldszmid, Romina S., Casper, P., Rivollier, A., White, S., Dsutsev, A., Hieny, S., Kelsall, B. et al., NK cell-derived interferon-γ orchestrates cellular dynamics and the differentiation of monocytes into dendritic cells at the site of infection. Immunity 2012. 36: 1047-1059.
    • (2012) Immunity , vol.36 , pp. 1047-1059
    • Goldszmid, R.S.1    Casper, P.2    Rivollier, A.3    White, S.4    Dsutsev, A.5    Hieny, S.6    Kelsall, B.7
  • 25
    • 0033230388 scopus 로고    scopus 로고
    • Paralysis of dendritic cell IL-12 production by microbial products prevents infection-induced immunopathology
    • Reis e Sousa, C., Yap, G., Schulz, O., Rogers, N., Schito, M., Aliberti, J., Hieny, S. et al., Paralysis of dendritic cell IL-12 production by microbial products prevents infection-induced immunopathology. Immunity 1999. 11: 637-647.
    • (1999) Immunity , vol.11 , pp. 637-647
    • Reis e Sousa, C.1    Yap, G.2    Schulz, O.3    Rogers, N.4    Schito, M.5    Aliberti, J.6    Hieny, S.7
  • 26
    • 0033230388 scopus 로고    scopus 로고
    • Paralysis of dendritic cell IL-12 production by microbial products prevents infection-induced immunopathology
    • Reis e Sousa, C., Yap, G., Schulz, O., Rogers, N., Schito, M., Aliberti, J., Hieny, S. et al., Paralysis of dendritic cell IL-12 production by microbial products prevents infection-induced immunopathology. Immunity 1999. 11: 637-647.
    • (1999) Immunity , vol.11 , pp. 637-647
    • Reis e Sousa, C.1    Yap, G.2    Schulz, O.3    Rogers, N.4    Schito, M.5    Aliberti, J.6    Hieny, S.7
  • 27
    • 0036141930 scopus 로고    scopus 로고
    • Lipoxin-mediated inhibition of IL-12 production by DCs: a mechanism for regulation of microbial immunity
    • Aliberti, J., Hieny, S., Reis e Sousa, C., Serhan, C. N. and Sher, A., Lipoxin-mediated inhibition of IL-12 production by DCs: a mechanism for regulation of microbial immunity. Nat. Immunol. 2002. 3: 76-82.
    • (2002) Nat. Immunol. , vol.3 , pp. 76-82
    • Aliberti, J.1    Hieny, S.2    Reis e Sousa, C.3    Serhan, C.N.4    Sher, A.5
  • 28
    • 0027240219 scopus 로고
    • Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells
    • D'Andrea, A., Aste-Amezaga, M., Valiante, N., Ma, X., Kubin, M. and Trinchieri, G., Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells. J. Exp. Med. 1993. 178: 1041-1048.
    • (1993) J. Exp. Med. , vol.178 , pp. 1041-1048
    • D'Andrea, A.1    Aste-Amezaga, M.2    Valiante, N.3    Ma, X.4    Kubin, M.5    Trinchieri, G.6
  • 29
    • 0032526338 scopus 로고    scopus 로고
    • Molecular mechanisms of the induction of IL-12 and its inhibition by IL-10
    • Aste-Amezaga, M., Ma, X., Sartori, A. and Trinchieri, G., Molecular mechanisms of the induction of IL-12 and its inhibition by IL-10. J. Immunol. 1998. 160: 5936-5944.
    • (1998) J. Immunol. , vol.160 , pp. 5936-5944
    • Aste-Amezaga, M.1    Ma, X.2    Sartori, A.3    Trinchieri, G.4
  • 30
    • 0032738991 scopus 로고    scopus 로고
    • Development of an assay to measure in vivo cytokine production in the mouse
    • Finkelman, F. and Morris, S., Development of an assay to measure in vivo cytokine production in the mouse. Int. Immunol. 1999. 11: 1811-1818.
    • (1999) Int. Immunol. , vol.11 , pp. 1811-1818
    • Finkelman, F.1    Morris, S.2
  • 31
    • 77649184739 scopus 로고    scopus 로고
    • The regulation of IL-10 production by immune cells
    • Saraiva, M. and O'Garra, A., The regulation of IL-10 production by immune cells. Nat. Rev. Immunol. 2010. 10: 170-181.
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 170-181
    • Saraiva, M.1    O'Garra, A.2
  • 33
    • 0026529405 scopus 로고
    • IL-10 inhibits parasite killing and nitrogen oxide production by IFN-gamma-activated macrophages
    • Gazzinelli, R., Oswald, I., James, S. and Sher, A., IL-10 inhibits parasite killing and nitrogen oxide production by IFN-gamma-activated macrophages. J. Immunol. 1992. 148: 1792-1796.
    • (1992) J. Immunol. , vol.148 , pp. 1792-1796
    • Gazzinelli, R.1    Oswald, I.2    James, S.3    Sher, A.4
  • 34
    • 0028272528 scopus 로고
    • Production of gamma interferon by natural killer cells from Toxoplasma gondii-infected SCID mice: regulation by interleukin-10, interleukin-12, and tumor necrosis factor alpha
    • Hunter, C., Subauste, C., Van Cleave, V. and Remington, J., Production of gamma interferon by natural killer cells from Toxoplasma gondii-infected SCID mice: regulation by interleukin-10, interleukin-12, and tumor necrosis factor alpha. Infect Immun. 1994. 62: 2818-2824.
    • (1994) Infect Immun. , vol.62 , pp. 2818-2824
    • Hunter, C.1    Subauste, C.2    Van Cleave, V.3    Remington, J.4
  • 35
    • 0029959459 scopus 로고    scopus 로고
    • In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha
    • Gazzinelli, R. T., Wysocka, M., Hieny, S., Scharton-Kersten, T., Cheever, A., Kuhn, R., Muller, W. et al., In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha. J. Immunol. 1996. 157: 798-805.
    • (1996) J. Immunol. , vol.157 , pp. 798-805
    • Gazzinelli, R.T.1    Wysocka, M.2    Hieny, S.3    Scharton-Kersten, T.4    Cheever, A.5    Kuhn, R.6    Muller, W.7
  • 36
    • 0031736936 scopus 로고    scopus 로고
    • Regulation and function of T-cell-mediated immunity during Toxoplasma gondii infection
    • Denkers, E. and Gazzinelli, R., Regulation and function of T-cell-mediated immunity during Toxoplasma gondii infection. Clin. Microbiol. Rev. 1998. 11: 569-588.
    • (1998) Clin. Microbiol. Rev. , vol.11 , pp. 569-588
    • Denkers, E.1    Gazzinelli, R.2
  • 37
    • 55149116512 scopus 로고    scopus 로고
    • The role of cytokines in the initiation, expansion, and control of cellular immunity to tuberculosis
    • Cooper, A. and Khader, S., The role of cytokines in the initiation, expansion, and control of cellular immunity to tuberculosis. Immunol. Rev. 2008. 226: 191-204.
    • (2008) Immunol. Rev. , vol.226 , pp. 191-204
    • Cooper, A.1    Khader, S.2
  • 38
    • 0030766165 scopus 로고    scopus 로고
    • The cytokine stew and innate resistance to L. monocytogenes
    • Mocci, S. and Dalrymple, S., The cytokine stew and innate resistance to L. monocytogenes. Immunol. Rev. 1997. 158: 107-114.
    • (1997) Immunol. Rev. , vol.158 , pp. 107-114
    • Mocci, S.1    Dalrymple, S.2
  • 39
    • 0037313578 scopus 로고    scopus 로고
    • Interleukin-12 and the regulation of innate resistance and adaptive immunity
    • Trinchieri, G., Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol. 2003. 3: 133-146.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 133-146
    • Trinchieri, G.1
  • 40
    • 70350738353 scopus 로고    scopus 로고
    • Programmed death-1 receptor negatively regulates LPS-mediated IL-12 production and differentiation of murine macrophage RAW264.7 cells
    • Cho, H., Choi, E., Lee, S., Jung, K., Seo, S., Choi, I., Park, S. et al., Programmed death-1 receptor negatively regulates LPS-mediated IL-12 production and differentiation of murine macrophage RAW264.7 cells. Immunol. Lett. 2009. 127: 39-47.
    • (2009) Immunol. Lett. , vol.127 , pp. 39-47
    • Cho, H.1    Choi, E.2    Lee, S.3    Jung, K.4    Seo, S.5    Choi, I.6    Park, S.7
  • 41
    • 84861536242 scopus 로고    scopus 로고
    • PD-1-mediated attrition of polyfunctional memory CD8+ T cells in chronic toxoplasma infection
    • Bhadra, R., Gigley, J. P. and Khan, I. A., PD-1-mediated attrition of polyfunctional memory CD8+ T cells in chronic toxoplasma infection. J. Infect Dis. 2012. 206: 125-134.
    • (2012) J. Infect Dis. , vol.206 , pp. 125-134
    • Bhadra, R.1    Gigley, J.P.2    Khan, I.A.3
  • 42
    • 79959357729 scopus 로고    scopus 로고
    • Control of toxoplasma reactivation by rescue of dysfunctional CD8+ T-cell response via PD-1-PDL-1 blockade
    • Bhadra, R., Gigley, J. P., Weiss, L. M. and Khan, I. A., Control of toxoplasma reactivation by rescue of dysfunctional CD8+ T-cell response via PD-1-PDL-1 blockade. Proc. Natl. Acad. Sci. USA 2011. 108: 9196-9201.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 9196-9201
    • Bhadra, R.1    Gigley, J.P.2    Weiss, L.M.3    Khan, I.A.4
  • 44
    • 75149188275 scopus 로고    scopus 로고
    • Systemic but not local infections elicit immunosuppressive IL-10 production by natural killer cells
    • Perona-Wright, G., Morhs, K., Szaba, F., Kummer, L., Madan, R., Karp, C., Johnson, L. et al., Systemic but not local infections elicit immunosuppressive IL-10 production by natural killer cells. Cell Host Microbe 2006. 6: 503-512.
    • (2006) Cell Host Microbe , vol.6 , pp. 503-512
    • Perona-Wright, G.1    Morhs, K.2    Szaba, F.3    Kummer, L.4    Madan, R.5    Karp, C.6    Johnson, L.7
  • 46
    • 0038273853 scopus 로고    scopus 로고
    • Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity
    • Curiel, T. J., Wei, S., Dong, H., Alvarez, X., Cheng, P., Mottram, P., Krzysiek, R. et al., Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity. Nat. Med. 2003. 9: 562-567.
    • (2003) Nat. Med. , vol.9 , pp. 562-567
    • Curiel, T.J.1    Wei, S.2    Dong, H.3    Alvarez, X.4    Cheng, P.5    Mottram, P.6    Krzysiek, R.7
  • 47
    • 84883493901 scopus 로고    scopus 로고
    • PD-L1 enhances CNS inflammation and infarct volume following experimental stroke in mice in opposition to PD-1
    • Bodhankar, S., Chen, Y., Vandenbark, A. A., Murphy, S. J. and Offner, H., PD-L1 enhances CNS inflammation and infarct volume following experimental stroke in mice in opposition to PD-1. J. Neuroinflammation 2013. 10: 111.
    • (2013) J. Neuroinflammation , vol.10 , pp. 111
    • Bodhankar, S.1    Chen, Y.2    Vandenbark, A.A.3    Murphy, S.J.4    Offner, H.5
  • 49
    • 0033180181 scopus 로고    scopus 로고
    • Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
    • Nishimura, H., Nose, M., Hiai, H., Minato, N. and Honjo, T., Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity 1999. 11: 141-151.
    • (1999) Immunity , vol.11 , pp. 141-151
    • Nishimura, H.1    Nose, M.2    Hiai, H.3    Minato, N.4    Honjo, T.5
  • 50
    • 84860123211 scopus 로고    scopus 로고
    • The inhibitory receptor PD-1 regulates IgA selection and bacterial composition in the gut
    • Kawamoto, S., Tran, T., Maruya, M., Suzuki, K., Doi, Y., Tsutsui, Y., Kato, L. et al., The inhibitory receptor PD-1 regulates IgA selection and bacterial composition in the gut. Science 2012. 336: 485-489.
    • (2012) Science , vol.336 , pp. 485-489
    • Kawamoto, S.1    Tran, T.2    Maruya, M.3    Suzuki, K.4    Doi, Y.5    Tsutsui, Y.6    Kato, L.7
  • 51
    • 34548131112 scopus 로고    scopus 로고
    • Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3- precursor cells in the absence of interleukin 10
    • Maynard, C., Harrington, L., Janowski, K., Oliver, J., Zindl, C., Rudensky, A. and Weaver, C., Regulatory T cells expressing interleukin 10 develop from Foxp3+ and Foxp3- precursor cells in the absence of interleukin 10. Nat. Immunol. 2007. 8: 931-941.
    • (2007) Nat. Immunol. , vol.8 , pp. 931-941
    • Maynard, C.1    Harrington, L.2    Janowski, K.3    Oliver, J.4    Zindl, C.5    Rudensky, A.6    Weaver, C.7
  • 52
    • 33845453812 scopus 로고    scopus 로고
    • Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knock in tiger mouse
    • Kamanaka, M., Kim, S., Wan, Y., Sutterwala, F., Lara-Tejero, M., Galan, J., Harhaj, E. et al., Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knock in tiger mouse. Immunity 2006. 25: 941-952.
    • (2006) Immunity , vol.25 , pp. 941-952
    • Kamanaka, M.1    Kim, S.2    Wan, Y.3    Sutterwala, F.4    Lara-Tejero, M.5    Galan, J.6    Harhaj, E.7
  • 53
    • 0030704726 scopus 로고    scopus 로고
    • A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
    • Groux, H., O'Garra, A., Bigler, M., Rouleau, M., Antonenko, S., de Vries, J. and Roncarolo, M., A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 1997. 389: 737-742.
    • (1997) Nature , vol.389 , pp. 737-742
    • Groux, H.1    O'Garra, A.2    Bigler, M.3    Rouleau, M.4    Antonenko, S.5    de Vries, J.6    Roncarolo, M.7
  • 55
    • 33749009709 scopus 로고    scopus 로고
    • Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction
    • Trautmann, L., Janbazian, L., Chomont, N., Said, E., Gimmig, S., Bessette, B., Boulassel, M. et al., Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction. Nat. Med. 2006. 12: 1198-1202.
    • (2006) Nat. Med. , vol.12 , pp. 1198-1202
    • Trautmann, L.1    Janbazian, L.2    Chomont, N.3    Said, E.4    Gimmig, S.5    Bessette, B.6    Boulassel, M.7
  • 56
    • 85047688548 scopus 로고    scopus 로고
    • Dysfunction of natural killer T cells in patients with active Mycobacterium tuberculosis infection
    • Kee, S., Kwon, Y., Park, Y., Cho, Y., Lee, S., Kim, T., Lee, S. et al., Dysfunction of natural killer T cells in patients with active Mycobacterium tuberculosis infection. Infect Immun. 2012. 80: 2100-2108.
    • (2012) Infect Immun. , vol.80 , pp. 2100-2108
    • Kee, S.1    Kwon, Y.2    Park, Y.3    Cho, Y.4    Lee, S.5    Kim, T.6    Lee, S.7
  • 57
    • 77954708517 scopus 로고    scopus 로고
    • Role played by the programmed death-1-programmed death ligand pathway during innate immunity against Mycobacterium tuberculosis
    • Alvarez, I., Pasquinelli, V., Jurado, J., Abbate, E., Musella, R., de la Barrera, S. and Garcia, V., Role played by the programmed death-1-programmed death ligand pathway during innate immunity against Mycobacterium tuberculosis. J. Infect Dis. 2010. 202: 524-532.
    • (2010) J. Infect Dis. , vol.202 , pp. 524-532
    • Alvarez, I.1    Pasquinelli, V.2    Jurado, J.3    Abbate, E.4    Musella, R.5    de la Barrera, S.6    Garcia, V.7
  • 58
    • 0031685190 scopus 로고    scopus 로고
    • Immunological studies on PD-1 deficient mice: implication of PD-1 as a negative regulator for B cell responses
    • Nishimura, H., Minato, N., Nakano, T. and Honjo, T., Immunological studies on PD-1 deficient mice: implication of PD-1 as a negative regulator for B cell responses. Int. Immunol. 1998. 10: 1563-1572.
    • (1998) Int. Immunol. , vol.10 , pp. 1563-1572
    • Nishimura, H.1    Minato, N.2    Nakano, T.3    Honjo, T.4
  • 59
    • 0029946887 scopus 로고    scopus 로고
    • Biochemical characterization and protein kinase C dependency of monokine-inducing activities of Toxoplasma gondii
    • Grunvald, E., Chiaramonte, M., Hieny, S., Wysocka, M., Trinchieri, G., Vogel, S., Gazzinelli, R. et al., Biochemical characterization and protein kinase C dependency of monokine-inducing activities of Toxoplasma gondii. Infect Immun. 1996. 64: 2010-2018.
    • (1996) Infect Immun. , vol.64 , pp. 2010-2018
    • Grunvald, E.1    Chiaramonte, M.2    Hieny, S.3    Wysocka, M.4    Trinchieri, G.5    Vogel, S.6    Gazzinelli, R.7
  • 60
    • 69049101205 scopus 로고    scopus 로고
    • A transmembrane domain-containing surface protein from Toxoplasma gondii augments replication in activated immune cells and establishment of a chronic infection
    • Pollard, A. M., Skariah, S., Mordue, D. G. and Knoll, L. J., A transmembrane domain-containing surface protein from Toxoplasma gondii augments replication in activated immune cells and establishment of a chronic infection. Infect Immun. 2009. 77: 3731-3739.
    • (2009) Infect Immun. , vol.77 , pp. 3731-3739
    • Pollard, A.M.1    Skariah, S.2    Mordue, D.G.3    Knoll, L.J.4
  • 61
    • 77950433922 scopus 로고    scopus 로고
    • Differential regulation of effector- and central-memory responses to Toxoplasma gondii infection by IL-12 revealed by tracking of Tgd057-specific CD8+ T cells
    • Wilson, D. C., Grotenbreg, G. M., Liu, K., Zhao, Y., Frickel, E. M., Gubbels, M. J., Ploegh, H. L. et al., Differential regulation of effector- and central-memory responses to Toxoplasma gondii infection by IL-12 revealed by tracking of Tgd057-specific CD8+ T cells. PLoS Pathog. 2010. 6: e1000815.
    • (2010) PLoS Pathog. , vol.6
    • Wilson, D.C.1    Grotenbreg, G.M.2    Liu, K.3    Zhao, Y.4    Frickel, E.M.5    Gubbels, M.J.6    Ploegh, H.L.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.