메뉴 건너뛰기




Volumn 23, Issue 3, 2013, Pages 139-151

Betahistine treatment in managing vertigo and improving vestibular compensation: Clarification

Author keywords

betahistine; histamine receptors; Vertigo; vestibular compensation

Indexed keywords

BETAHISTINE; HISTAMINE; HISTAMINE RECEPTOR;

EID: 84893575406     PISSN: 09574271     EISSN: None     Source Type: Journal    
DOI: 10.3233/VES-130496     Document Type: Review
Times cited : (56)

References (91)
  • 1
    • 0038574710 scopus 로고    scopus 로고
    • Double-blind, randomized, multicenter study comparing the effect of betahistine and flunarizine on the dizziness handicap in patients with recurrent vestibular vertigo
    • R. Albera, R. Ciuffolotti, M. Di Cicco, G. De Benedittis, I. Grazioli, G. Melzi et al., Double-blind, randomized, multicenter study comparing the effect of betahistine and flunarizine on the dizziness handicap in patients with recurrent vestibular vertigo, Acta Otolaryngol 123 (2003), 598-593.
    • (2003) Acta Otolaryngol , vol.123 , pp. 598-593
    • Albera, R.1    Ciuffolotti, R.2    Di Cicco, M.3    De Benedittis, G.4    Grazioli, I.5    Melzi, G.6
  • 2
    • 0020587209 scopus 로고
    • Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor
    • J.M. Arrang, M. Garbag and J.C. Schwartz, Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor, Nature 302 (1983), 832-837.
    • (1983) Nature , vol.302 , pp. 832-837
    • Arrang, J.M.1    Garbag, M.2    Schwartz, J.C.3
  • 3
    • 0021983475 scopus 로고
    • Actions of betahistine at histamine receptors in the brain
    • J.M. Arrang, M. Garbag, T.T. Quach et al., Actions of betahistine at histamine receptors in the brain, Eur J Pharmacol 111 (1985), 73-84.
    • (1985) Eur J Pharmacol , vol.111 , pp. 73-84
    • Arrang, J.M.1    Garbag, M.2    Quach, T.T.3
  • 4
    • 0023639903 scopus 로고
    • Autoregulation of histamine synthesis in brain mediated by presynaptic H3 receptors
    • J.M. Arrang, M. Garbag and J.C. Schwartz, Autoregulation of histamine synthesis in brain mediated by presynaptic H3 receptors, Neurosci 23 (1987), 149-157.
    • (1987) Neurosci , vol.23 , pp. 149-157
    • Arrang, J.M.1    Garbag, M.2    Schwartz, J.C.3
  • 5
    • 33845307950 scopus 로고    scopus 로고
    • Central histaminergic modulation of vestibular function-A review
    • F. Bergquist and M.B. Dutia, Central histaminergic modulation of vestibular function-a review, Acta Physiol Sin 58 (2006), 293-304.
    • (2006) Acta Physiol Sin , vol.58 , pp. 293-304
    • Bergquist, F.1    Dutia, M.B.2
  • 6
    • 33845288296 scopus 로고    scopus 로고
    • Histaminergic and glycinergic modulation of GABA release in the vestibular nuclei of normal and labyrinthectomized rats
    • F. Bergquist, A. Ruthven, M. Ludwig and M.B. Dutia, Histaminergic and glycinergic modulation of GABA release in the vestibular nuclei of normal and labyrinthectomized rats, J Physiol (Lond) 577 (2006), 857-868.
    • (2006) J Physiol (Lond) , vol.577 , pp. 857-868
    • Bergquist, F.1    Ruthven, A.2    Ludwig, M.3    Dutia, M.B.4
  • 13
    • 0034353582 scopus 로고    scopus 로고
    • A review of medical treatment for Menière's disease
    • J. Claes and P.H. van de Heyning, A review of medical treatment for Menière's disease, Acta Otolaryngol Suppl 544 (2000), 34-39.
    • (2000) Acta Otolaryngol Suppl , vol.544 , pp. 34-39
    • Claes, J.1    Heyning De Van, P.H.2
  • 14
    • 0034353583 scopus 로고    scopus 로고
    • Medical treatment in Menière's disease: Avoiding vestibular neurectomy and facilitating postoperative compensation
    • V. Coletti, Medical treatment in Menière's disease: Avoiding vestibular neurectomy and facilitating postoperative compensation, Acta Otolaryngol Suppl 544 (2000), 27-33.
    • (2000) Acta Otolaryngol Suppl , vol.544 , pp. 27-33
    • Coletti, V.1
  • 15
    • 0028936479 scopus 로고
    • Vestibular compensation: A review of the oculomotor, neural, and clinical consequences of unilateral vestibular loss
    • I.S. Curthoys and G.M. Halmagyi, Vestibular compensation: A review of the oculomotor, neural, and clinical consequences of unilateral vestibular loss, J Vest Res 5 (1995), 67-107.
    • (1995) J Vest Res , vol.5 , pp. 67-107
    • Curthoys, I.S.1    Halmagyi, G.M.2
  • 16
    • 33744940327 scopus 로고    scopus 로고
    • Molecular mechanisms of recovery from vestibular damage in mammals: Recent advances
    • C.L. Darlington and P.F. Smith, Molecular mechanisms of recovery from vestibular damage in mammals: Recent advances, Prog Neurobiol 623 (2000), 13-25.
    • (2000) Prog Neurobiol , vol.623 , pp. 13-25
    • Darlington, C.L.1    Smith, P.F.2
  • 18
    • 80051698484 scopus 로고    scopus 로고
    • The neurogenetic potential of the vestibular nuclei and the recovery time course in the adult cat are governed by different mechanisms depending on the nature of the vestibular damage
    • S. Dutheil, M. Lacour and B. Tighilet, The neurogenetic potential of the vestibular nuclei and the recovery time course in the adult cat are governed by different mechanisms depending on the nature of the vestibular damage, Plos One 6(8) (2011), e22262.
    • (2011) Plos One , vol.6 , Issue.8
    • Dutheil, S.1    Lacour, M.2    Tighilet, B.3
  • 19
    • 77957758457 scopus 로고    scopus 로고
    • Mechanisms of vestibular compensation: Recent advances
    • M.B. Dutia, Mechanisms of vestibular compensation: Recent advances, Curr Opin Otolaryng and Head Neck Surg 18 (2010), 420-424.
    • (2010) Curr Opin Otolaryng and Head Neck Surg , vol.18 , pp. 420-424
    • Dutia, M.B.1
  • 21
    • 0025924551 scopus 로고
    • Histamine in the treatment of vertigo
    • A.J.E. Fisher, Histamine in the treatment of vertigo, Acta Otolaryngol 479 (1991), 24-28.
    • (1991) Acta Otolaryngol , vol.479 , pp. 24-28
    • Fisher, A.J.E.1
  • 22
    • 0034964592 scopus 로고    scopus 로고
    • Binding affinity profile of betahistine and its metabolites for central histamine receptors of rodents
    • A. Fossati, D. Barone and C. Benvenuti, Binding affinity profile of betahistine and its metabolites for central histamine receptors of rodents, Pharmacol Res 43 (2001), 389-392.
    • (2001) Pharmacol Res , vol.43 , pp. 389-392
    • Fossati, A.1    Barone, D.2    Benvenuti, C.3
  • 23
    • 0017099031 scopus 로고
    • Betahistine dihydrochloride in Menière's disease
    • I.J.C. Frew and G.N. Menon, Betahistine dihydrochloride in Menière's disease, Postgrad Med J 52 (1976), 501-503.
    • (1976) Postgrad Med J , vol.52 , pp. 501-503
    • Frew, I.J.C.1    Menon, G.N.2
  • 24
    • 67649988392 scopus 로고    scopus 로고
    • Comparable efficacy and tolerability between twice daily and three times daily betahistine for Menière's disease
    • M.M. Ganança, H.H. Caovilla and F.F. Ganança, Comparable efficacy and tolerability between twice daily and three times daily betahistine for Menière's disease, Acta Otolaryngol 129(5) (2009), 487-492.
    • (2009) Acta Otolaryngol , vol.129 , Issue.5 , pp. 487-492
    • Ganança, M.M.1    Caovilla, H.H.2    Ganança, F.F.3
  • 26
    • 0024477922 scopus 로고
    • Effects of histamine H3-receptor ligands on various biochemical indices of histaminergic neuron activity in the brain
    • M. Garbag, M.D. Tuong, C. Gros and J.C. Schwartz, Effects of histamine H3-receptor ligands on various biochemical indices of histaminergic neuron activity in the brain, Eur J Pharmacol 164 (1989), 1-11.
    • (1989) Eur J Pharmacol , vol.164 , pp. 1-11
    • Garbag, M.1    Tuong, M.D.2    Gros, C.3    Schwartz, J.C.4
  • 27
    • 77956255306 scopus 로고    scopus 로고
    • Effects of betahistine at histamine H3 receptors: Mixed inverse agonism/agonism in vitro and partial inverse agonism in vivo
    • F. Gbahou, E. Davenas, S. Morisset and J.M. Arrang, Effects of betahistine at histamine H3 receptors: mixed inverse agonism/agonism in vitro and partial inverse agonism in vivo, J Pharmacol Exp Ther 334 (2010), 945-954.
    • (2010) J Pharmacol Exp Ther , vol.334 , pp. 945-954
    • Gbahou, F.1    Davenas, E.2    Morisset, S.3    Arrang, J.M.4
  • 28
    • 84867019250 scopus 로고    scopus 로고
    • Vestibular rehabilitation: Election treatment method for compensating vestibular impairment
    • M. Georgescu, S. Stoian, C.A.Mogoanta and G.V. Ciubotaru, Vestibular rehabilitation: election treatment method for compensating vestibular impairment, Rom J Morphol Embryol 53(3) (2012), 651-656.
    • (2012) Rom J Morphol Embryol , vol.53 , Issue.3 , pp. 651-656
    • Georgescu, M.1    Stoian, S.2    Mogoanta, C.A.3    Ciubotaru, G.V.4
  • 29
    • 0025328598 scopus 로고
    • Distribution properties, and functional characteristics of three classes of histamine receptors
    • S.J. Hill, Distribution, properties, and functional characteristics of three classes of histamine receptors, Pharmacol Rev 42 (1990), 45-83.
    • (1990) Pharmacol Rev , vol.42 , pp. 45-83
    • Hill, S.J.1
  • 30
    • 0027372455 scopus 로고
    • Effect of unilateral vestibular stimulation on histamine release from the hypothalamus of rats in vivo
    • A. Horii, N. Takeda, T. Matsunaga et al., Effect of unilateral vestibular stimulation on histamine release from the hypothalamus of rats in vivo, Neurophysiol 90 (1993), 1822-1826.
    • (1993) Neurophysiol , vol.90 , pp. 1822-1826
    • Horii, A.1    Takeda, N.2    Matsunaga, T.3
  • 31
    • 84862644826 scopus 로고    scopus 로고
    • Betahistine exerts a dose-dependent effect on cochlear stria vascularis blood flow in guinea pigs in vivo
    • F. Ihler, M. Bertlich, K. Sharaf, S. Strieth, M. Strupp and M. Canis, Betahistine exerts a dose-dependent effect on cochlear stria vascularis blood flow in guinea pigs in vivo, PloS One 7(6) (2012), e39086.
    • (2012) PloS One , vol.7 , Issue.6
    • Ihler, F.1    Bertlich, M.2    Sharaf, K.3    Strieth, S.4    Strupp, M.5    Canis, M.6
  • 32
    • 0032908697 scopus 로고    scopus 로고
    • Effects of the antihistaminergic drugs diphenhydramine and zolantidine on vestibular-induced hypothalamic neuronal activity in the guinea pig
    • A. Inokuchi, F. Liu, S. Yokomitsu, M. Ureshino and S. Komiyama, Effects of the antihistaminergic drugs diphenhydramine and zolantidine on vestibular-induced hypothalamic neuronal activity in the guinea pig, Eur Arch Otorhinolaryngol 256 (1999), S22-S266.
    • (1999) Eur Arch Otorhinolaryngol , vol.256
    • Inokuchi, A.1    Liu, F.2    Yokomitsu, S.3    Ureshino, M.4    Komiyama, S.5
  • 33
    • 0003323339 scopus 로고
    • Effects of histamine on rat medial vestibular nucleus neurons recorded intracellularly in vitro
    • D.J. Inverarity, A.R. Johnston, D.S. McQueen and M.B. Dutia, Effects of histamine on rat medial vestibular nucleus neurons recorded intracellularly in vitro, J Physiol (Lond) 459 (1993), 466P.
    • (1993) J Physiol (Lond) , vol.459
    • Inverarity, D.J.1    Johnston, A.R.2    McQueen, D.S.3    Dutia, M.B.4
  • 34
    • 0015034892 scopus 로고
    • Effects of diphenhydramine and dimenhydrinate on vestibular neuronal activity of cat: A search for the locus of their anti-motion sickness action
    • B.P. Jaju and S.C. Wang, Effects of diphenhydramine and dimenhydrinate on vestibular neuronal activity of cat: a search for the locus of their anti-motion sickness action, J Pharmacol Exp Therap 176 (1971), 718-724.
    • (1971) J Pharmacol Exp Therap , vol.176 , pp. 718-724
    • Jaju, B.P.1    Wang, S.C.2
  • 36
    • 33745914952 scopus 로고    scopus 로고
    • Menière's disease
    • A.L. James and M. Thorp, Menière's disease, Clin Evid 14 (2005), 659-665.
    • (2005) Clin Evid , vol.14 , pp. 659-665
    • James, A.L.1    Thorp, M.2
  • 38
    • 0030846758 scopus 로고    scopus 로고
    • The dosedependent effect of betahistine on vestibulo-ocular reflex: A double-blind, placebo-controlled study in patients with paroxysmal vertigo
    • H. Kingma, M. Bonink, A.Meulenbroeks et al., The dosedependent effect of betahistine on vestibulo-ocular reflex: a double-blind, placebo-controlled study in patients with paroxysmal vertigo, Acta Otolaryngol (Stockh) 117 (1997), 1-6.
    • (1997) Acta Otolaryngol (Stockh) , vol.117 , pp. 1-6
    • Kingma, H.1    Bonink, M.2    Meulenbroeks, A.3
  • 39
    • 0017049898 scopus 로고
    • Microiontophoresis of acetylcholine histamine and their antagonists on neurons in the medial and lateral vestibular nuclei of the cat
    • E.B. Kirsten and J.N. Sharma, Microiontophoresis of acetylcholine, histamine and their antagonists on neurons in the medial and lateral vestibular nuclei of the cat, Neuropharmacol 15 (1976), 743-753.
    • (1976) Neuropharmacol , vol.15 , pp. 743-753
    • Kirsten, E.B.1    Sharma, J.N.2
  • 41
    • 33749012296 scopus 로고    scopus 로고
    • Restoration of vestibular function: Basic aspects and practical advances for rehabilitation
    • M. Lacour, Restoration of vestibular function: basic aspects and practical advances for rehabilitation, Current Med Res and Opinion 22 (2006), 1651-1659.
    • (2006) Current Med Res and Opinion , vol.22 , pp. 1651-1659
    • Lacour, M.1
  • 42
    • 0035211581 scopus 로고    scopus 로고
    • Histamine and betahistine in the treatment of vertigo: Elucidation of mechanisms of action
    • M. Lacour and O. Sterkers, Histamine and betahistine in the treatment of vertigo: Elucidation of mechanisms of action, CNS Drugs 15 (2001), 853-870.
    • (2001) CNS Drugs , vol.15 , pp. 853-870
    • Lacour, M.1    Sterkers, O.2
  • 43
    • 75649119666 scopus 로고    scopus 로고
    • Plastic events in the vestibular nuclei during vestibular compensation: The brain orchestration of a deafferentation code
    • M. Lacour and B. Tighilet, Plastic events in the vestibular nuclei during vestibular compensation: the brain orchestration of a deafferentation code, Rest Neurol Neurosci 28 (2010), 19-35.
    • (2010) Rest Neurol Neurosci , vol.28 , pp. 19-35
    • Lacour, M.1    Tighilet, B.2
  • 45
    • 0030926643 scopus 로고    scopus 로고
    • Sensory strategies in human postural control before and after unilateralvestibular neurectomy
    • M. Lacour, J. Barthélémy, L. Borel, J. Magnan and M. Ouaknine, Sensory strategies in human postural control before and after unilateralvestibular neurectomy, Exp Brain Res 115 (1997), 300-310.
    • (1997) Exp Brain Res , vol.115 , pp. 300-310
    • Lacour, M.1    Barthélémy, J.2    Borel, L.3    Magnan, J.4    Ouaknine, M.5
  • 47
    • 66149105038 scopus 로고    scopus 로고
    • Tell me your vestibular deficit, and I'll tell you how you'll compensate
    • M. Lacour, S. Dutheil, C. Lopez, B. Tighilet and L. Borel, Tell me your vestibular deficit, and I'll tell you how you'll compensate, Ann NY Acad Sci 1164 (2009), 268-278.
    • (2009) Ann NY Acad Sci , vol.1164 , pp. 268-278
    • Lacour, M.1    Dutheil, S.2    Lopez, C.3    Tighilet, B.4    Borel, L.5
  • 49
    • 0031941664 scopus 로고    scopus 로고
    • The vascular mechanism of action of betahistine in the inner ear of the guinea pig
    • E.A. Laurikainen, J.M. Miller, A.L. Nattall and W.S. Quirk, The vascular mechanism of action of betahistine in the inner ear of the guinea pig, Eur Arch Otorhinolaryngol 255 (1998), 199-123.
    • (1998) Eur Arch Otorhinolaryngol , vol.255 , pp. 199-123
    • Laurikainen, E.A.1    Miller, J.M.2    Nattall, A.L.3    Quirk, W.S.4
  • 50
    • 79960204109 scopus 로고    scopus 로고
    • High-dosage betahistine dihydrochloride between 288 and 480 mg/day in patients with severe Menière's disease: A case series
    • F. Lezins, C. Adrion, U. Mansmann, K. Jahn and M. Strupp, High-dosage betahistine dihydrochloride between 288 and 480 mg/day in patients with severe Menière's disease: A case series, Eur Arch Otorhinolaryngol 268 (2011), 1237-1240.
    • (2011) Eur Arch Otorhinolaryngol , vol.268 , pp. 1237-1240
    • Lezins, F.1    Adrion, C.2    Mansmann, U.3    Jahn, K.4    Strupp, M.5
  • 51
    • 14044275765 scopus 로고    scopus 로고
    • The histamine H3 receptor: From gene cloning to H3 receptor drugs
    • R. Leurs, R.A. Bakker, H. Timmerman and I.J. de Esch, The histamine H3 receptor: From gene cloning to H3 receptor drugs, Nat Rev Drug Discov 4 (2005), 107-120.
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 107-120
    • Leurs, R.1    Bakker, R.A.2    Timmerman, H.3    De Esch, I.J.4
  • 52
    • 12944281502 scopus 로고    scopus 로고
    • Plasticity of histamine H3 receptor expression and binding in the vestibular nuclei after labyrinthectomy in rat
    • A.F. Lozada, A.A. Aarnisalo, K. Karlstedt, H. Stark and P. Panula, Plasticity of histamine H3, receptor expression and binding in the vestibular nuclei after labyrinthectomy in rat, BMC Neurosci 5 (2004), 32.
    • (2004) BMC Neurosci , vol.5 , pp. 32
    • Lozada, A.F.1    Aarnisalo, A.A.2    Karlstedt, K.3    Stark, H.4    Panula, P.5
  • 53
    • 77749343157 scopus 로고    scopus 로고
    • Functional organization of vestibular commissural connections in frog
    • D. Malinvaud, I. Vassias, I. Reichenberger et al., Functional organization of vestibular commissural connections in frog, J Neurosci 30 (2010), 3310-3325.
    • (2010) J Neurosci , vol.30 , pp. 3310-3325
    • Malinvaud, D.1    Vassias, I.2    Reichenberger, I.3
  • 54
    • 0015465093 scopus 로고
    • The effect of Serc (betahistine dihydrochloride) on the circulation of the inner ear in experimental animals
    • D.M. Martinez, The effect of Serc (betahistine dihydrochloride) on the circulation of the inner ear in experimental animals, Acta Otolaryngol Suppl 305 (1972), 29-47.
    • (1972) Acta Otolaryngol Suppl , vol.305 , pp. 29-47
    • Martinez, D.M.1
  • 55
    • 37349035647 scopus 로고    scopus 로고
    • Improving the quality of life in patients with vestibular disorders: The role of medical treatments and physical rehabilitation
    • E.Mira, Improving the quality of life in patients with vestibular disorders: the role of medical treatments and physical rehabilitation, Int J Clin Pract 62 (2008), 109-114.
    • (2008) Int J Clin Pract , vol.62 , pp. 109-114
    • Mira, E.1
  • 57
    • 0021366546 scopus 로고
    • Betahistine dihydrochloride in the treatment of vertigo of peripheral origin: A double blind placebocontrolled study
    • W.J. Oosterveld, Betahistine dihydrochloride in the treatment of vertigo of peripheral origin: a double blind placebocontrolled study, J Laryngol Otol 98 (1984), 37-41.
    • (1984) J Laryngol Otol , vol.98 , pp. 37-41
    • Oosterveld, W.J.1
  • 59
    • 0024603246 scopus 로고
    • Histamine-immunoreactive fibers in the rat brain
    • P. Panula, U. Pirvola, S. Auvinen and M.S. Atraksinen, Histamine-immunoreactive fibers in the rat brain, Neurosci 22 (1989), 585-610.
    • (1989) Neurosci , vol.22 , pp. 585-610
    • Panula, P.1    Pirvola, U.2    Auvinen, S.3    Atraksinen, M.S.4
  • 60
    • 84876410921 scopus 로고    scopus 로고
    • Histamine excites neurons of the inferior vestibular nucleus in rats by activation of H1 and H2 receptors
    • S.Y. Peng, Q.X. Zhuang, Y.C. He et al., Histamine excites neurons of the inferior vestibular nucleus in rats by activation of H1 and H2 receptors, Neurosci Lett 541 (2013), 87-92.
    • (2013) Neurosci Lett , vol.541 , pp. 87-92
    • Peng, S.Y.1    Zhuang, Q.X.2    He, Y.C.3
  • 61
    • 0025190343 scopus 로고
    • Histamine depolarizes rat medial vestibular nucleus neurons recorded intracellularly in vitro
    • K.D. Phelan, J. Nakamura and J.P. Gallagher, Histamine depolarizes rat medial vestibular nucleus neurons recorded intracellularly in vitro, Neurosci Lett 109 (1990), 287-292.
    • (1990) Neurosci Lett , vol.109 , pp. 287-292
    • Phelan, K.D.1    Nakamura, J.2    Gallagher, J.P.3
  • 62
    • 38249036485 scopus 로고
    • Histamine neuronal pathways and their function
    • H. Pollard and J.C. Schwartz, Histamine neuronal pathways and their function, Trends Neurosci 10 (1987), 86-9.
    • (1987) Trends Neurosci , vol.10 , pp. 86-89
    • Pollard, H.1    Schwartz, J.C.2
  • 63
    • 0028845945 scopus 로고
    • Antivertigo medications and drug-induced vertigo
    • O. Rascol, T.C. Hain, C. Brefel et al., Antivertigo medications and drug-induced vertigo, Drugs 50 (1995), 777-791.
    • (1995) Drugs , vol.50 , pp. 777-791
    • Rascol, O.1    Hain, T.C.2    Brefel, C.3
  • 64
    • 79953773354 scopus 로고    scopus 로고
    • Betahistine treatment improves the recovery of static symptoms in patients with unilateral vestibular loss
    • C. Redon, C. Lopez, L. Bernard-Demanze, M. Dumitrescu, J. Magnan, M. Lacour and L. Borel, Betahistine treatment improves the recovery of static symptoms in patients with unilateral vestibular loss, J Clin Pharmacol 51 (2011), 438-448.
    • (2011) J Clin Pharmacol , vol.51 , pp. 438-448
    • Redon, C.1    Lopez, C.2    Bernard-Demanze, L.3    Dumitrescu, M.4    Magnan, J.5    Lacour, M.6    Borel, L.7
  • 65
    • 0028874362 scopus 로고
    • Neuronal activity in the ipsilateral vestibular nucleus following unilateral labyrinthectomy in the alert guinea pig
    • L. Ris, C. Dewaele, M. Serafin et al., Neuronal activity in the ipsilateral vestibular nucleus following unilateral labyrinthectomy in the alert guinea pig, J Neurophysiol 74 (1995), 2087-2095.
    • (1995) J Neurophysiol , vol.74 , pp. 2087-2095
    • Ris, L.1    Dewaele, C.2    Serafin, M.3
  • 66
    • 0031730126 scopus 로고    scopus 로고
    • Neuronal activity in the vestibular nuclei after contralateral or bilateral labyrinthectomy in the alert guinea pig
    • L. Ris and E. Godaux, Neuronal activity in the vestibular nuclei after contralateral or bilateral labyrinthectomy in the alert guinea pig, J Neurophysiol 80 (1998), 2352-2367.
    • (1998) J Neurophysiol , vol.80 , pp. 2352-2367
    • Ris, L.1    Godaux, E.2
  • 67
    • 0017325153 scopus 로고
    • Iontophoretic studies of histamine and histamine antagonists in the feline vestibular nuclei
    • J. Satayavivad and E.B. Kirsten, Iontophoretic studies of histamine and histamine antagonists in the feline vestibular nuclei, Eur J Pharmacol 41 (1977), 17-26.
    • (1977) Eur J Pharmacol , vol.41 , pp. 17-26
    • Satayavivad, J.1    Kirsten, E.B.2
  • 68
    • 84861066218 scopus 로고    scopus 로고
    • Comparison of the therapeutic efficacy of a fixed low-dose combination of cinnarizine and dimenhydrinate with betahistine in vestibular neuritis: A randomized, double-blind, non-inferiority study
    • A.W. Scholtz, R. Steindl, N. Burchardi, I. Bognar-Steinberg and W. Baumann, Comparison of the therapeutic efficacy of a fixed low-dose combination of cinnarizine and dimenhydrinate with betahistine in vestibular neuritis: a randomized, double-blind, non-inferiority study, Clin Drug Invest 32(6) (2012), 387-399.
    • (2012) Clin Drug Invest , vol.32 , Issue.6 , pp. 387-399
    • Scholtz, A.W.1    Steindl, R.2    Burchardi, N.3    Bognar-Steinberg, I.4    Baumann, W.5
  • 69
    • 0014884509 scopus 로고
    • Properties and regional distribution of histidine decarboxylase in rat brain
    • J.C. Schwartz, C. Lampart and C. Rose, Properties and regional distribution of histidine decarboxylase in rat brain, J Neurochem 17 (1970), 1527-1534.
    • (1970) J Neurochem , vol.17 , pp. 1527-1534
    • Schwartz, J.C.1    Lampart, C.2    Rose, C.3
  • 70
    • 0027310555 scopus 로고
    • Medial vestibular nucleus in the guinea-pig: Histaminergic receptors. I. An in vitro study
    • M. Serafin, A. Khateb, N. Vibert et al., Medial vestibular nucleus in the guinea-pig: histaminergic receptors. I. An in vitro study, Exp Brain Res 93 (1993), 242-248.
    • (1993) Exp Brain Res , vol.93 , pp. 242-248
    • Serafin, M.1    Khateb, A.2    Vibert, N.3
  • 71
    • 0024399939 scopus 로고
    • Mechanisms of recovery following unilateral labyrinthectomy: A review
    • P.F. Smith and I.S. Curthoys, Mechanisms of recovery following unilateral labyrinthectomy: a review, Brain Res Rev 14 (1989), 155-180.
    • (1989) Brain Res Rev , vol.14 , pp. 155-180
    • Smith, P.F.1    Curthoys, I.S.2
  • 72
    • 0023850079 scopus 로고
    • Neuronal activity in the ipsilateral medial vestibular nucleus of the guinea pig following unilateral labyrinthectomy
    • P.F. Smith and I.S. Curthoys, Neuronal activity in the ipsilateral medial vestibular nucleus of the guinea pig following unilateral labyrinthectomy, Brain Res 444 (1988), 308-319.
    • (1988) Brain Res , vol.444 , pp. 308-319
    • Smith, P.F.1    Curthoys, I.S.2
  • 73
    • 0023835345 scopus 로고
    • Neuronal activity in the contralateral medial vestibular nucleus of the guinea pig following unilateral labyrinthectomy
    • P.F. Smith and I.S. Curthoys, Neuronal activity in the contralateral medial vestibular nucleus of the guinea pig following unilateral labyrinthectomy, Brain Res 444 (1988), 295-307.
    • (1988) Brain Res , vol.444 , pp. 295-307
    • Smith, P.F.1    Curthoys, I.S.2
  • 74
    • 77950200975 scopus 로고    scopus 로고
    • Neuropharmacology of vestibular system disorders
    • E. Soto and R. Vega, Neuropharmacology of vestibular system disorders, Curr Neuropharmacol 8 (2010), 26-40.
    • (2010) Curr Neuropharmacol , vol.8 , pp. 26-40
    • Soto, E.1    Vega, R.2
  • 75
    • 80052678088 scopus 로고    scopus 로고
    • Betahistine produces a postsynaptic inhibition on the excitability of the primary afferent neurons in the vestibular endorgans
    • E. Soto, H. Chavez, P. Valli, C. Benvenuti and R. Vega, Betahistine produces a postsynaptic inhibition on the excitability of the primary afferent neurons in the vestibular endorgans, Acta Otolaryngol Suppl 121 (2001), 19-24.
    • (2001) Acta Otolaryngol Suppl , vol.121 , pp. 19-24
    • Soto, E.1    Chavez, H.2    Valli, P.3    Benvenuti, C.4    Vega, R.5
  • 76
    • 80054776513 scopus 로고    scopus 로고
    • Effect of treatment with betahistine dihydrochloride on the postural stability in patients with different duration of benign paroxysmal positional vertigo
    • K. Stambolieva and G. Angov, Effect of treatment with betahistine dihydrochloride on the postural stability in patients with different duration of benign paroxysmal positional vertigo, Int Tinnitus J 16(1) (2010), 32-36.
    • (2010) Int Tinnitus J , vol.16 , Issue.1 , pp. 32-36
    • Stambolieva, K.1    Angov, G.2
  • 77
    • 42249105280 scopus 로고    scopus 로고
    • Vertigo and dizziness: Treatment of benign paroxysmal positioning vertigo, vestibular neuritis and Menière's disease
    • L. Candelise, ed, Oxford, Blackwell Publishing
    • M. Strupp, C. Cnyrim and T. Brandt, Vertigo and dizziness: treatment of benign paroxysmal positioning vertigo, vestibular neuritis and Menière's disease. In: Evidence-based neurology-management of neurological disorders, L. Candelise, ed, Oxford, Blackwell Publishing (2007), 59-69.
    • (2007) Evidence-based Neurology-management of Neurological Disorders , pp. 59-69
    • Strupp, M.1    Cnyrim, C.2    Brandt, T.3
  • 78
    • 42249098421 scopus 로고    scopus 로고
    • Long-term prophylactic treatment of attacks of vertigo in Menière's disease: Comparison of a high with a low dosage of betahistine in an open trial
    • M. Strupp, D. Hupert, C. Frenzel, J. Wagner, A. Hahn, K. Jahn, V.C. Zingler, U. Mansmann and T. Brandt, Long-term prophylactic treatment of attacks of vertigo in Menière's disease: Comparison of a high with a low dosage of betahistine in an open trial, Acta Otolaryngol 128 (2008), 520-524.
    • (2008) Acta Otolaryngol , vol.128 , pp. 520-524
    • Strupp, M.1    Hupert, D.2    Frenzel, C.3    Wagner, J.4    Hahn, A.5    Jahn, K.6    Zingler, V.C.7    Mansmann, U.8    Brandt, T.9
  • 79
    • 0029893428 scopus 로고    scopus 로고
    • Distribution of histaminergic axonal fibres in the vestibular nuclei of the cat
    • B. Tighilet and M. Lacour, Distribution of histaminergic axonal fibres in the vestibular nuclei of the cat, Neuroreport 7 (1996), 873-878.
    • (1996) Neuroreport , vol.7 , pp. 873-878
    • Tighilet, B.1    Lacour, M.2
  • 80
    • 0030790517 scopus 로고    scopus 로고
    • Histamine immunoreactivity changes in vestibular-lesioned and histaminergic-treated cats
    • B. Tighilet and M. Lacour, Histamine immunoreactivity changes in vestibular-lesioned and histaminergic-treated cats, Eur J Pharmacol 330 (1997), 65-77.
    • (1997) Eur J Pharmacol , vol.330 , pp. 65-77
    • Tighilet, B.1    Lacour, M.2
  • 81
    • 0028837330 scopus 로고
    • Betahistine dihydrochloride treatment facilitates vestibular compensation in the cat
    • B. Tighilet, J. Leonard and M. Lacour, Betahistine dihydrochloride treatment facilitates vestibular compensation in the cat, J Vest Res 5 (1995), 53-66.
    • (1995) J Vest Res , vol.5 , pp. 53-66
    • Tighilet, B.1    Leonard, J.2    Lacour, M.3
  • 82
    • 0037141768 scopus 로고    scopus 로고
    • Betahistine dihydrochloride interaction with the histaminergic system in the cat: Neurochemical and molecular mechanisms
    • B. Tighilet, S. Trottier, C. Mourre, C. Chotard and M. Lacour, Betahistine dihydrochloride interaction with the histaminergic system in the cat: neurochemical and molecular mechanisms, Eur J Pharmacol 446 (2002), 63-73.
    • (2002) Eur J Pharmacol , vol.446 , pp. 63-73
    • Tighilet, B.1    Trottier, S.2    Mourre, C.3    Chotard, C.4    Lacour, M.5
  • 83
    • 27644497244 scopus 로고    scopus 로고
    • Dose-and durationdependent effects of betahistine dihydrochloride treatment on histamine turnover in the cat
    • B. Tighilet, S. Trottier and M. Lacour, Dose-and durationdependent effects of betahistine dihydrochloride treatment on histamine turnover in the cat, Eur J Pharmacol 523 (2005), 54-63.
    • (2005) Eur J Pharmacol , vol.523 , pp. 54-63
    • Tighilet, B.1    Trottier, S.2    Lacour, M.3
  • 84
    • 33744900643 scopus 로고    scopus 로고
    • Changes in the histaminergic system during vestibular compensation in the cat
    • B. Tighilet, S. Trottier, C. Mourre and M. Lacour, Changes in the histaminergic system during vestibular compensation in the cat, J Physiol (Lond) 573 (2006), 723-739.
    • (2006) J Physiol (Lond) , vol.573 , pp. 723-739
    • Tighilet, B.1    Trottier, S.2    Mourre, C.3    Lacour, M.4
  • 85
    • 34347221881 scopus 로고    scopus 로고
    • Histaminergic ligands improve vestibular compensation in the cat: Behavioural, neurochemical and molecular evidence
    • B. Tighilet, C. Mourre, S. Trottier and M. Lacour, Histaminergic ligands improve vestibular compensation in the cat: behavioural, neurochemical and molecular evidence, Eur J Pharmacol 568 (2007), 149-163.
    • (2007) Eur J Pharmacol , vol.568 , pp. 149-163
    • Tighilet, B.1    Mourre, C.2    Trottier, S.3    Lacour, M.4
  • 87
    • 0030926072 scopus 로고    scopus 로고
    • Histamine release from the hypothalamus induced by gravity changes in rats and space motion sickness
    • A. Uno, N. Takeda, A. Horii, M. Morita, Y. Yamamoto, A. Yamatodani et al., Histamine release from the hypothalamus induced by gravity changes in rats and space motion sickness, Physiol Behav 61 (1997), 883-887.
    • (1997) Physiol Behav , vol.61 , pp. 883-887
    • Uno, A.1    Takeda, N.2    Horii, A.3    Morita, M.4    Yamamoto, Y.5    Yamatodani, A.6
  • 88
    • 0029036733 scopus 로고
    • Effects of histamine and betahistine on rat medial vestibular nucleus neurons: Possible mechanisms of action of antihistaminergic drugs in vertigo and motion sickness
    • J.J. Wang and M.B. Dutia, Effects of histamine and betahistine on rat medial vestibular nucleus neurons: possible mechanisms of action of antihistaminergic drugs in vertigo and motion sickness, Exp Brain Res 105 (1995), 18-24.
    • (1995) Exp Brain Res , vol.105 , pp. 18-24
    • Wang, J.J.1    Dutia, M.B.2
  • 90
    • 0027734009 scopus 로고
    • Recovery of head postural control following unilateral vestibular neurectomy in the cat: Neck muscle activity and neuronal correlates in the Deiters' nuclei
    • Y. Zennou-Azogui, L. Borel and M. Lacour, Recovery of head postural control following unilateral vestibular neurectomy in the cat: Neck muscle activity and neuronal correlates in the Deiters' nuclei, Acta Otolaryngol (Stockh) Suppl 509 (1993), 1-19.
    • (1993) Acta Otolaryngol (Stockh) Suppl , vol.509 , pp. 1-19
    • Zennou-Azogui, Y.1    Borel, L.2    Lacour, M.3
  • 91
    • 55749098774 scopus 로고    scopus 로고
    • Histamine excites rat lateral vestibular nuclear neurons through activation of post-synaptic H2 receptors
    • J. Zhang, X.H. Han, H.Z. Li, J.N. Zhu and J.J. Wang, Histamine excites rat lateral vestibular nuclear neurons through activation of post-synaptic H2 receptors, Neurosci Lett 448 (2008), 15-19.
    • (2008) Neurosci Lett , vol.448 , pp. 15-19
    • Zhang, J.1    Han, X.H.2    Li, H.Z.3    Zhu, J.N.4    Wang, J.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.