Phosphatidylinositol-3,4,5-triphosphate-dependent rac exchange factor 1 regulates epinephrine-induced exocytosis of weibel-palade bodies

Journal of Thrombosis and Haemostasis

Volumn 12, Issue 2, 2014, Pages 273-281

  van Hooren, K W E M ^a   van Breevoort, D ^a   Fernandez Borja, M ^a   Meijer, A B ^a,b   Eikenboom, J ^c   Bierings, R ^a   Voorberg, J ^a,d  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^d UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Endothelial cells; Human; PREX1 protein; Rac1 GTP binding protein; Von Willebrand factor; Weibel Palade bodies

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ADRENALIN; CYCLIC AMP; GLUTATHIONE TRANSFERASE; P21 ACTIVATED KINASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRIPHOSPHATE DEPENDENT RAC EXCHANGE FACTOR 1 PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; RAC1 PROTEIN; THROMBIN; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR;

ARTICLE; BETA CHAIN; CONTROLLED STUDY; DOWN REGULATION; EXOCYTOSIS; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEOMICS; RNA INTERFERENCE; STIMULATION; UMBILICAL VEIN ENDOTHELIAL CELL; WEIBEL PALADE BODY;

ENDOTHELIAL CELLS; HUMAN; PREX1 PROTEIN; RAC1 GTP BINDING PROTEIN; VON WILLEBRAND FACTOR; WEIBEL-PALADE BODIES;

CYCLIC AMP; EPINEPHRINE; EXOCYTOSIS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; PHOSPHATIDYLINOSITOL PHOSPHATES; RAC1 GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; VON WILLEBRAND FACTOR; WEIBEL-PALADE BODIES;

EID: 84893546754     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/jth.12460     Document Type: Article

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