Up-regulation of miR-200b in biliary atresia patients accelerates proliferation and migration of hepatic stallate cells by activating PI3K/Akt signaling

Cellular Signalling

Volumn 26, Issue 5, 2014, Pages 925-932

  Xiao, Yongtao ^a,b,c   Wang, Jun ^a,c   Chen, Yingwei ^b,c   Zhou, Kejun ^b,c   Wen, Jie ^b,c   Wang, Yang ^b,c   Zhou, Ying ^a,c   Pan, Weihua ^a,c   Cai, Wei ^a,b,c  

^a XINHUA HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Shanghai Institute of Pediatric Research   (China)

^c Key Laboratory of Nutrition and Metabolism   (China)

Author keywords

Biliary atresia; Hepatic stellate cells; Liver fibrosis; Migration; MiR 200b; Proliferation

Indexed keywords

BILIARY ATRESIA; HEPATIC STELLATE CELLS; LIVER FIBROSIS; MIGRATION; MIR-200B; PROLIFERATION;

BILIARY ATRESIA; CELL LINE; CELL MOVEMENT; CELL PROLIFERATION; CHROMONES; DNA-BINDING PROTEINS; DOWN-REGULATION; HEPATIC STELLATE CELLS; HUMANS; LIVER CIRRHOSIS; MATRIX METALLOPROTEINASE 2; MICRORNAS; MORPHOLINES; PHOSPHATIDYLINOSITOL 3-KINASE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

2 MORPHOLINO 8 PHENYLCHROMONE; FOG2 PROTEIN; GELATINASE A; MICRORNA; MICRORNA 200B; MICRORNA 8; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN; PROTEIN KINASE B; PROTEIN P85; UNCLASSIFIED DRUG;

ARTICLE; BILE DUCT ATRESIA; CELL ACTIVATION; CELL GROWTH; CELL IMMORTALIZATION; CELL MIGRATION; CELL PROLIFERATION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DOWN REGULATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER FIBROSIS; PATHOGENESIS; PROTEIN BINDING; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STELLATE CELL; UPREGULATION;

EID: 84893523352     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2014.01.003     Document Type: Article

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