Endothelial sirtuin 1 deficiency perpetrates nephrosclerosis through downregulation of matrix metalloproteinase-14: Relevance to fibrosis of vascular senescence

Journal of the American Society of Nephrology

Volumn 25, Issue 2, 2014, Pages 276-291

  Vasko, Radovan ^a,b   Xavier, Sandhya ^a   Chen, Jun ^a   Lin, Chi Hua Sarah ^a   Ratliff, Brian ^a   Rabadi, May ^a   Maizel, Julien ^a   Tanokuchi, Rina ^a   Zhang, Frank ^a   Cao, Jian ^c   Goligorsky, Michael S ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^c STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; COLLAGEN TYPE 1; COLLAGEN TYPE 3; CONCANAVALIN A; CREATININE; ENDOGLIN; EOTAXIN; FOLIC ACID; INTERLEUKIN 1; INTERLEUKIN 6; METALLOPROTEINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; SIRTUIN 1; TUMOR NECROSIS FACTOR ALPHA;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DETERIORATION; DOWN REGULATION; ENDOTHELIAL PROGENITOR CELL; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME DEFICIENCY; EXON; HETEROZYGOTE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VIVO STUDY; KIDNEY DISEASE; KIDNEY FUNCTION; KIDNEY INJURY; MALE; MOUSE; NEPHROSCLEROSIS; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENESCENCE; VASCULAR FIBROSIS; VASODILATATION;

ACUTE KIDNEY INJURY; ANIMALS; CELL AGING; CONCANAVALIN A; DOWN-REGULATION; ENDOTHELIUM, VASCULAR; EXONS; EXTRACELLULAR MATRIX; FIBROSIS; FOLIC ACID; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; KIDNEY; KIDNEY FAILURE, CHRONIC; MALE; MATRIX METALLOPROTEINASE 14; MICE; MICE, MUTANT STRAINS; MICE, TRANSGENIC; NEOVASCULARIZATION, PHYSIOLOGIC; NEPHROSCLEROSIS; REGENERATION; SIRTUIN 1; VASODILATION;

EID: 84893470726     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2013010069     Document Type: Article

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