TIMP-2 is released as an intact molecule following binding to MT1-MMP on the cell surface

Experimental Cell Research

Volumn 293, Issue 1, 2004, Pages 164-174

  Zucker, Stanley ^a,b   Hymowitz, Michelle ^a   Conner, Cathleen ^a   DeClerck, Yves ^c   Cao, Jian ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Degradation; Endocytosis; Matrix metalloproteinase (MMP); Plasma membrane; Receptor; Tissue inhibitor of metalloproteinases (TIMP); Trafficking

Indexed keywords

BAFILOMYCIN A1; CELL SURFACE RECEPTOR; COMPLEMENTARY DNA; CONCANAVALIN A; DYNAMIN; ENZYME INHIBITOR; ENZYME PRECURSOR; IODINE 125; MACROLIDE; MATRIX METALLOPROTEINASE 14; MEMBRANE-TYPE 1 MATRIX METALLOPROTEINASE; METALLOPROTEINASE; MUTANT PROTEIN; PROTEIN INHIBITOR; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ANIMAL; ANIMAL CELL; ARTICLE; BIOTINYLATION; CELL MEMBRANE; CELL STRAIN COS1; CELL SURFACE; CERCOPITHECUS; DRUG EFFECT; ENDOCYTOSIS; ENDOSOME; ENZYME ACTIVATION; EPITHELIUM CELL; FIBROSARCOMA; HUMAN; INCUBATION TIME; INTRACELLULAR SPACE; KINETICS; LYSOSOME; METABOLISM; MOLECULE; NONHUMAN; PATHOLOGY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN SECRETION; RECEPTOR BINDING; TEMPERATURE; TUMOR CELL LINE; WESTERN BLOTTING;

EID: 0346690071     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2003.10.007     Document Type: Article

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