Yeast Pre-rRNA Processing and Modification Occur Cotranscriptionally

Molecular Cell

Volumn 37, Issue 6, 2010, Pages 809-820

  Koš, Martin ^a   Tollervey, David ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

DNA; RNA; SYSBIO

Indexed keywords

RIBOSOME RNA; RNA 18S;

ARTICLE; CHEMICAL LABELING; KINETICS; MATHEMATICAL MODEL; NONHUMAN; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN MODIFICATION; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; RNA METHYLATION; RNA PROCESSING; YEAST;

BASE SEQUENCE; METHYLATION; MOLECULAR SEQUENCE DATA; RNA PRECURSORS; RNA, TRANSFER; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION, GENETIC;

EID: 77949563362     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2010.02.024     Document Type: Article

References (23)

1. Bellí G., Garí E., Aldea M., and Herrero E. Functional analysis of yeast essential genes using a promoter-substitution cassette and the tetracycline-regulatable dual expression system. Yeast 14 (1998) 1127-1138
2. Brand R.C., Klootwijk J., van Steenbergen T.J.M., de Kok A.J., and Planta R.J. Secondary methylation of yeast ribosomal precursor RNA. Eur. J. Biochem. 75 (1977) 311-318
3. Dez C., and Tollervey D. Ribosome synthesis meets the cell cycle. Curr. Opin. Microbiol. 7 (2004) 631-637
4. Dez C., Froment C., Noaillac-Depeyre J., Monsarrat B., Caizergues-Ferrer M., and Henry Y. Npa1p, a component of very early Pre-60S ribosomal particles, associates with a subset of small nucleolar RNPs required for peptidyl transferase center modification. Mol. Cell. Biol. 24 (2004) 6324-6337
5. French S.L., Osheim Y.N., Cioci F., Nomura M., and Beyer A.L. In exponentially growing Saccharomyces cerevisiae cells, rRNA synthesis is determined by the summed RNA polymerase I loading rate rather than by the number of active genes. Mol. Cell. Biol. 23 (2003) 1558-1568
6. Grandi P., Rybin V., Bassler J., Petfalski E., Strauss D., Marzioch M., Schafer T., Kuster B., Tschochner H., Tollervey D., et al. 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors. Mol. Cell 10 (2002) 105-115
7. Greenberg H., and Penman S. Methylation and processing of ribosomal RNA in HeLa cells. J. Mol. Biol. 21 (1966) 527-535
8. Henras A., Soudet J., Gérus M., Lebaron S., Caizergues-Ferrer M., Mougin A., and Henry Y. The post-transcriptional steps of eukaryotic ribosome biogenesis. Cell. Mol. Life Sci. 65 (2008) 2334-2359
9. Houseley J., and Tollervey D. The many pathways of RNA degradation. Cell 136 (2009) 763-776
10. Jund R., Chevallier M.R., and Lacroute F. Uracil transport in Saccharomyces cerevisiae. J. Membr. Biol. 36 (1977) 233-251
11. Lacroute F. Regulation of pyrimidine biosynthesis in Saccharomyces cerevisiae. J. Bacteriol. 95 (1968) 824-832
12. 6A dimethylation in the 3′-terminal loop of 18S rRNA is essential in yeast. J. Mol. Biol. 241 (1994) 492-497
13. Osheim Y.N., French S.L., Keck K.M., Champion E.A., Spasov K., Dragon F., Baserga S.J., and Beyer A.L. Pre-18S ribosomal RNA is structurally compacted into the SSU processome prior to being cleaved from nascent transcripts in Saccharomyces cerevisiae. Mol. Cell 16 (2004) 943-954
14. Osheim Y.N., French S.L., Sikes M.L., and Beyer A.L. Electron microscope visualization of RNA transcription and processing in Saccharomyces cerevisiae by Miller chromatin spreading. The Nucleus (2009), Humana Press, Totowa, NJ 55-69
15. Sambrook J., Fritsch E.F., and Maniatis T. Molecular Cloning (1989), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
16. Seron K., Blondel M.-O., Haguenauer-Tsapis R., and Volland C. Uracil-induced down-regulation of the yeast uracil permease. J. Bacteriol. 181 (1999) 1793-1800
17. Tollervey D. A yeast small nuclear RNA is required for normal processing of pre-ribosomal RNA. EMBO J. 6 (1987) 4169-4175
18. Trapman J., and Planta R.J. Detailed analysis of the ribosomal RNA synthesis in yeast. Biochim. Biophys. Acta 414 (1975) 115-125
19. Trapman J., Retèl J., and Planta R.J. Ribosomal precursor particles from yeast. Exp. Cell Res. 90 (1975) 95-104
20. Udem S.A., and Warner J.R. Ribosomal RNA synthesis in Saccharomyces cerevisiae. J. Mol. Biol. 65 (1972) 227-242
21. Udem S.A., and Warner J.R. The cytoplasmic maturation of a ribosomal precursor ribonucleic acid in yeast. J. Biol. Chem. 248 (1973) 1412-1416
22. Venema J., and Tollervey D. Ribosome synthesis in Saccharomyces cerevisiae. Annu. Rev. Genet. 33 (1999) 261-311
23. Warner J.R. The economics of ribosome biosynthesis in yeast. Trends Biochem. Sci. 24 (1999) 437-440