Shikonin inhibits the lipopolysaccharide-induced release of HMGB1 in RAW264.7 cells via IFN and NF-κB signaling pathways

International Immunopharmacology

Volumn 19, Issue 1, 2014, Pages 81-87

  Yang, Ying ^a   Wang, Jing ^a   Yang, Qiao ^b   Wu, Shanshan ^a   Yang, Zhenggang ^a   Zhu, Haihong ^a   Zheng, Min ^a   Liu, Weixia ^a   Wu, Wei ^a   He, Jiliang ^c   Chen, Zhi ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

High mobility group box 1; IFN ; Lipopolysaccharides; Macrophages; NF B; Shikonin

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; BETA INTERFERON; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE; SHIKONIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOPLASM; DOSE RESPONSE; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; MURINAE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; SUPERNATANT; WESTERN BLOTTING;

HIGH MOBILITY GROUP BOX 1; IFN-Β; LIPOPOLYSACCHARIDES; MACROPHAGES; NF-ΚB; SHIKONIN;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; HMGB1 PROTEIN; INTERFERON-BETA; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MICE; NAPHTHOQUINONES; NITRIC OXIDE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84893423960     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2014.01.003     Document Type: Article

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