Carbon monoxide from CORM-2 reduces HMGB1 release through regulation of IFN-β/JAK2/STAT-1/INOS/NO signaling but not COX-2 in TLR-activated macrophages

Shock

Volumn 34, Issue 6, 2010, Pages 608-614

  Tsoyi, Konstantin ^a   Nizamutdinova, Irina Tsoy ^a   Jang, Hwa Jin ^a   Mun, Lidiya ^a   Kim, Hye Jung ^a   Seo, Han Geuk ^a   Lee, Jae Heun ^a   Chang, Ki Churl ^a  

^a Gyeongsang National University School of Medicine   (South Korea)

Author keywords

CORM 2; COX 2; HMGB1; iNOS; JAK STAT pathway; sepsis

Indexed keywords

3,3 BIS(2 AMINOETHYL) 1 HYDROXY 2 OXOTRIAZENE; BETA INTERFERON; CARBON MONOXIDE; CARBON MONOXIDE RELEASING MOLECULE 2; CYCLOOXYGENASE 2; FLUDARABINE; HIGH MOBILITY GROUP B1 PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; JANUS KINASE 2; LIPOPOLYSACCHARIDE; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PEPTIDOGLYCAN; POLYINOSINIC POLYCYTIDYLIC ACID; SMALL INTERFERING RNA; STAT1 PROTEIN; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CECUM; CELL VIABILITY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; LUNG PARENCHYMA; MACROPHAGE; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SEPSIS; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CARBON MONOXIDE; CELL LINE; CELL SURVIVAL; CYCLOOXYGENASE 2; HMGB1 PROTEIN; INTERFERON-BETA; JANUS KINASE 2; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; ORGANOMETALLIC COMPOUNDS; PEPTIDOGLYCAN; POLY I-C; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

EID: 78649599278     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e3181e46f15     Document Type: Article

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