Linking genetic variants of the mineralocorticoid receptor and negative memory bias: Interaction with prior life adversity

Psychoneuroendocrinology

Volumn 40, Issue 1, 2014, Pages 181-190

  Vogel, Susanne ^a   Gerritsen, Lotte ^a,b   van Oostrom, Iris ^a   Arias Vásquez, Alejandro ^a   Rijpkema, Mark ^a   Joëls, Marian ^c   Franke, Barbara ^a   Tendolkar, Indira ^a,d   Fernández, Guillén ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^d UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

Gene life adversity interaction; Memory bias; Mineralocorticoid receptor; NR3C2

Indexed keywords

MINERALOCORTICOID RECEPTOR;

ADULT; ARTICLE; DEPRESSION; DISEASE PREDISPOSITION; FEMALE; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; LIFE EVENT; MAJOR CLINICAL STUDY; MALE; MEMORY BIAS; MOOD DISORDER; NR3C2 GENE; PRIORITY JOURNAL; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; YOUNG ADULT;

GENE×LIFE ADVERSITY INTERACTION; MEMORY BIAS; MINERALOCORTICOID RECEPTOR; NR3C2;

ADOLESCENT; ADULT; DEPRESSIVE DISORDER; FEMALE; GENE-ENVIRONMENT INTERACTION; GENETIC LINKAGE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LIFE CHANGE EVENTS; MALE; MEMORY; MOOD DISORDERS; NEGATIVISM; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, MINERALOCORTICOID; YOUNG ADULT;

EID: 84893391516     PISSN: 03064530     EISSN: 18733360     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2013.11.010     Document Type: Article

References (55)

1. Anacker C., Zunszain P.A., Carvalho L.A., Pariante C.M. The glucocorticoid receptor: pivot of depression and of antidepressant treatment?. Psychoneuroendocrino 2011, 36:415-425.
2. Beck A.T. The evolution of the cognitive model of depression and its neurobiological correlates. Am. J. Psychiatry 2008, 165:969-977.
3. Bogdan R., Williamson D.E., Hariri A.R. Mineralocorticoid receptor iso/val (rs5522) genotype moderates the association between previous childhood emotional neglect and amygdala reactivity. Am. J. Psychiatry 2012, 169:515-522.
4. Bouma E.M.C., Riese H., Nolte I.M., Oosterom E., Verhulst F.C., Ormel J., et al. No associations between single nucleotide polymorphisms in corticoid receptor genes and heart rate and cortisol responses to a standardized social stress test in adolescents: the TRAILS study. Behav. Genet. 2011, 41:253-261.
5. Bralten J., Arias-Vasquez A., Makkinje R., Veltman J.A., Brunner H.G., Fernandez G., et al. Association of the Alzheimer's gene SORL1 with hippocampal volume in young healthy adults. Am. J. Psychiatry 2011, 168:1083-1089.
6. Bremner J.D., Narayan M., Anderson E.R., Staib L.H., Miller H.L., Charney D.S. Hippocampal volume reduction in major depression. Am. J. Psychiatry 2000, 157:115-118.
7. Brinks V., Berger S., Gass P., de Kloet E.R., Oitzl M.S. Mineralocorticoid receptors in control of emotional arousal and fear memory. Horm. Behav. 2009, 56:232-238.
8. Brugha T., Bebbington P., Tennant C., Hurry J. The list of threatening experiences - a subset of 12 event categories with considerable long-term contextual threat. Psychol. Med. 1985, 15:189-194.
9. Caspi A., Sugden K., Moffitt T.E., Taylor A., Craig I.W., Harrington H., et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 2003, 301:386-389.
10. Chan S.W.Y., Goodwin G.M., Harmer C.J. Highly neurotic never-depressed students have negative biases in information processing. Psychol. Med. 2007, 37:1281-1291.
11. Collins P.Y., Patel V., Joestl S.S., March D., Insel T.R., Daar A.S., et al. Grand challenges in global mental health. Nature 2011, 475:27-30.
12. Deelen J., Uh H.-W., Monajemi R., van Heemst D., Thijssen P., Böhringer S., et al. Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways. AGE 2011, 1-15.
13. DeRijk R.H., de Kloet E.R. Corticosteroid receptor polymorphisms: determinants of vulnerability and resilience. Eur. J. Pharmacol. 2008, 583:303-311.
14. DeRijk R.H., de Kloet E.R., Zitman F.G., van Leeuwen N. Mineralocorticoid receptor gene variants as determinants of HPA axis regulation and behavior. Endocr. Dev. 2011, 20:137-148.
15. Franke B., Neale B., Faraone S. Genome-wide association studies in ADHD. Hum. Genet. 2009, 126:13-50.
16. Frodl T., Meisenzahl E., Zetzsche T., Bottlender R., Born C., Groll C., et al. Enlargement of the amygdala in patients with a first episode of major depression. Biol. Psychiatr. 2002, 51:708-714.
17. Gass P., Kretz O., Wolfer D.P., Berger S., Tronche F., Reichardt H.M., et al. Genetic disruption of mineralocorticoid receptor leads to impaired neurogenesis and granule cell degeneration in the hippocampus of adult mice. EMBO Rep. 2000, 1:447-451.
18. Geller D.S., Rodriguez-Soriano J., Boado A.V., Schifter S., Bayer M., Chang S.S., et al. Mutations in the mineralocorticoid receptor gene cause autosomal dominant pseudohypoaldosteronism type I. Nat. Genet. 1998, 19:279-281.
19. Germine L., Nakayama K., Duchaine B., Chabris C., Chatterjee G., Wilmer J. Is the web as good as the lab? Comparable performance from web and lab in cognitive/perceptual experiments. Psychon. Bull. Rev. 2012, 19:847-857.
20. Gerritsen L., Rijpkema M., van Oostrom I., Buitelaar J., Franke B., Fernández G., et al. Amygdala to hippocampal volume ratio is associated with negative memory bias in healthy subjects. Psychosom. Med. 2011, 42:335-343.
21. Gottesman I.I., Gould T.D. The endophenotype concept in psychiatry: etymology and strategic intentions. Am. J. Psychiatry 2003, 160:636-645.
22. Groeneweg F.L., Karst H., de Kloet E.R., Joëls M. Rapid non-genomic effects of corticosteroids and their role in the Central stress response. J. Endocrinol. 2011, 209:153-167.
23. Hammen C., Zupan B.A. Self-schemas, depression, and the processing of personal information in children. J. Exp. Child Psychol. 1984, 37:598-608.
24. Hasler G., Drevets W.C., Manji H.K., Charney D.S. Discovering endophenotypes for major depression. Neuropsychopharmacol 2004, 29:1765-1781.
25. Joels M., Karst H., DeRijk R., de Kloet E.R. The coming out of the brain mineralocorticoid receptor. Trends Neurosci. 2008, 31:1-7.
26. Karg K., Sen S. Gene×environment interaction models in psychiatric genetics. Curr. Top. Behav. Neurosci. 2012, 12:441-462.
27. Kendler K.S., Karkowski L.M., Prescott C.A. Causal relationship between stressful life events and the onset of major depression. Am. J. Psychiatry 1999, 156:837-841.
28. Kendler K.S., Neale M.C. Endophenotype: a conceptual analysis. Mol. Psychiatry 2010, 15:789-797.
29. Kessler R., Berglund P., Demler O., Jin R., Merikangas K., Walters E. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the national comorbidity survey replication. Arch. Gen. Psychiatry 2005, 62:593-602.
30. King M.J., MacDougall A.G., Ferris S.M., Levine B., MacQueen G.M., McKinnon M.C. A review of factors that moderate autobiographical memory performance in patients with major depressive disorder. J. Clin. Exp. Neuropsyc. 2010, 32:1122-1144.
31. Klengel T., Binder E.B. Gene-environment interactions in major depressive disorder. Can. J. Psychiat. 2013, 58:76-83.
32. Klok M.D., Alt S.R., Irurzun Lafitte A.J.M., Turner J.D., Lakke E.A.J.F., Huitinga I., et al. Decreased expression of mineralocorticoid receptor mrna and its splice variants in postmortem brain regions of patients with major depressive disorder. J. Psychiatr. Res. 2011, 45:871-878.
33. Klok M.D., Giltay E.J., Van der Does A.J.W., Geleijnse J.M., Antypa N., Penninx B.W.J.H., et al. A common and functional mineralocorticoid receptor haplotype enhances optimism and protects against depression in females. Transl. Psychiatry 2011, 1:e62.
34. Kriegeskorte N., Simmons W.K., Bellgowan P.S.F., Baker C.I. Circular analysis in systems neuroscience: the dangers of double dipping. Nat. Neurosci. 2009, 12:535-540.
35. Kuningas M., de Rijk R.H., Westendorp R.G.J., Jolles J., Eline Slagboom P., van Heemst D. Mental performance in old age dependent on cortisol and genetic variance in the mineralocorticoid and glucocorticoid receptors. Neuropsychopharmacology 2006, 32:1295-1301.
36. Leppanen J.M. Emotional information processing in mood disorders: a review of behavioral and neuroimaging findings. Curr. Opin. Psychiatry 2006, 19:34-39.
37. Mathers C.D., Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med. 2006, 3:e442.
38. Mathews A., MacLeod C. Cognitive vulnerability to emotional disorders. Annu. Rev. Clin. Psychol. 2005, 1:167-195.
39. Nossent A.Y., Hansen J.L., Doggen C., Quax P.H.A., Sheikh S.P., Rosendaal F.R. SNPs in microrna binding sites in 3'-UTRs of RAAS genes influence arterial blood pressure and risk of myocardial infarction. Am. J. Hypertens. 2011, 24:999-1006.
40. Otte C., Hinkelmann K., Moritz S., Yassouridis A., Jahn H., Wiedemann K., et al. Modulation of the mineralocorticoid receptor as add-on treatment in depression: a randomized, double-blind, placebo-controlled proof-of-concept study. J. Psychiatr. Res. 2010, 44:339-346.
41. Purcell S., Neale B., Todd-Brown K., Thomas L., Ferreira M.A.R., Bender D., et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 2007, 81:559-575.
42. Riepe F.G., Finkeldei J., de Sanctis L., Einaudi S., Testa A., Karges B., et al. Elucidating the underlying molecular pathogenesis of NR3C2 mutants causing autosomal dominant pseudohypoaldosteronism type 1. J. Clin. Endocrinol. Metab. 2006, 91:4552-4561.
43. Riepe F.G., Krone N., Morlot M., Peter M., Sippell W.G., Partsch C.J. Autosomal-dominant pseudohypoaldosteronism type 1 in a Turkish family is associated with a novel nonsense mutation in the human mineralocorticoid receptor gene. J. Clin. Endocrinol. Metab. 2004, 89:2150-2152.
44. Rosmalen J.G.M., Bos E.H., de Jonge P. Validation of the Long-term Difficulties Inventory (LDI) and the List of Threatening Experiences (LTE) as measures of stress in epidemiological population-based cohort studies. Psychol. Med. 2012, 42:2599-2608.
45. Schwender H., Ruczinski I., Ickstadt K. Testing SNPs and sets of SNPs for importance in association studies. Biostatistics 2011, 12:18-32.
46. Stein J.L., Medland S.E., Vasquez A.A., Hibar D.P., Senstad R.E., Winkler A.M., et al. Identification of common variants associated with human hippocampal and intracranial volumes. Nat. Genet. 2012, 44:552-561.
47. Supriyanto I., Sasada T., Fukutake M., Asano M., Ueno Y., Nagasaki Y., et al. Association of FKBP5 gene haplotypes with completed suicide in the Japanese population. Prog Neuro-Psychopharmacol. 2011, 35:252-256.
48. Symons C.S., Johnson B.T. The self-reference effect in memory: a meta-analysis. Psychol. Bull. 1997, 121:371-394.
49. van Leeuwen N. Mineralocorticoid receptor gene variants. Implications for stress, blood pressure and personality 2010, Ph.D. Thesis, University Leiden, Leiden.
50. van Leeuwen N., Bellingrath S., de Kloet E.R., Zitman F.G., DeRijk R.H., Kudielka B.M., et al. Human mineralocorticoid receptor (MR) gene haplotypes modulate MR expression and transactivation: implication for the stress response. Psychoneuroendocrinology 2011, 36:699-709.
51. van Oostrom I., Franke B., Arias Vasquez A., Rinck M., Tendolkar I., Verhagen M., et al. Never-depressed females with a family history of depression demonstrate affective bias. Psychiatry Res. 2013, 205:54-58.
52. van Oostrom I., Franke B., Rijpkema M., Gerritsen L., Arias-Vásquez A., Fernández G., et al. Interaction between BDNF Val66Met and childhood stressful life events is associated to affective memory bias in men but not women. Biol. Psychol. 2012, 89:214-219.
53. Velders F.P., Kuningas M., Kumari M., Dekker M.J., Uitterlinden A.G., Kirschbaum C., et al. Genetics of cortisol secretion and depressive symptoms: a candidate gene and genome wide association approach. Psychoneuroendocrinology 2011, 36:1053-1061.
54. Wilkinson P.O., Goodyer I.M. Childhood adversity and allostatic overload of the hypothalamic-pituitary-adrenal axis: a vulnerability model for depressive disorders. Development and Psychopathology 2011, 23:1017-1037.
55. Zhou M., Bakker E.H.M., Velzing E.H., Berger S., Oitzl M., Joels M., Krugers H.J. Both mineralocorticoid and glucocorticoid receptors regulate emotional memory in mice. Neurobiol. Learn. Mem. 2010, 94:530-537.