메뉴 건너뛰기




Volumn 63, Issue 2, 2014, Pages 417-426

Kenyan purple tea anthocyanins and coenzyme-Q10 ameliorate post treatment reactive encephalopathy associated with cerebral human African trypanosomiasis in murine model

Author keywords

Brain; Coenzyme Q10; Encephalopathy; Human African trypanosomiasis; Melarsoprol; Purple tea anthocyanins

Indexed keywords

ACONITASE 1; ACONITATE HYDRATASE; ANTHOCYANIN; ANTIOXIDANT; DIMINAZENE ACETURATE; GLUTATHIONE; MELARSOPROL; UBIDECARENONE; UNCLASSIFIED DRUG;

EID: 84893378759     PISSN: 13835769     EISSN: 18730329     Source Type: Journal    
DOI: 10.1016/j.parint.2014.01.001     Document Type: Article
Times cited : (18)

References (52)
  • 2
    • 0000240697 scopus 로고
    • Melarsoprol in the treatment of human trypanosomiasis
    • Friedheim E.A.H. Melarsoprol in the treatment of human trypanosomiasis. Am J Trop Med Hyg 1949, 29:173-180.
    • (1949) Am J Trop Med Hyg , vol.29 , pp. 173-180
    • Friedheim, E.A.H.1
  • 3
    • 0028366196 scopus 로고
    • The treatment of human African trypanosomiasis
    • Pepin J., Milrod F. The treatment of human African trypanosomiasis. Adv Parasitol 1994, 33:1-47.
    • (1994) Adv Parasitol , vol.33 , pp. 1-47
    • Pepin, J.1    Milrod, F.2
  • 4
    • 33646487124 scopus 로고    scopus 로고
    • Diagnostic and neuropathogenesis issues in human African trypanosomiasis
    • Kennedy P.G.E. Diagnostic and neuropathogenesis issues in human African trypanosomiasis. Int J Parasitol 2006, 36:505-512.
    • (2006) Int J Parasitol , vol.36 , pp. 505-512
    • Kennedy, P.G.E.1
  • 5
    • 0020668981 scopus 로고
    • Relapsed parasitaemia following chemotherapy of chronic Trypanosoma brucei infections in mice and its relation to cerebral trypanosomes
    • Jennings F.W., Gray G.D. Relapsed parasitaemia following chemotherapy of chronic Trypanosoma brucei infections in mice and its relation to cerebral trypanosomes. Contrib Microbiol Immunol 1983, 7:147-154.
    • (1983) Contrib Microbiol Immunol , vol.7 , pp. 147-154
    • Jennings, F.W.1    Gray, G.D.2
  • 6
    • 0033386196 scopus 로고    scopus 로고
    • The pathogenesis and modulation of the post-treatment reactive encephalopathy in a mouse model of human African trypanosomiasis
    • Kennedy P.G.E. The pathogenesis and modulation of the post-treatment reactive encephalopathy in a mouse model of human African trypanosomiasis. J Neuroimmunol 1999, 100:36-41.
    • (1999) J Neuroimmunol , vol.100 , pp. 36-41
    • Kennedy, P.G.E.1
  • 7
    • 0022641903 scopus 로고
    • Human African trypanosomiasis (T. b. gambiense): a study of 16 fatal cases of sleeping sickness with some observations on acute reactive arsenical encephalopathy
    • Adams J.H., Haller L., Boa F.Y., Dago F., Dago A., Konian K. Human African trypanosomiasis (T. b. gambiense): a study of 16 fatal cases of sleeping sickness with some observations on acute reactive arsenical encephalopathy. Neuropathol Appl Neurobiol 1986, 12:81-94.
    • (1986) Neuropathol Appl Neurobiol , vol.12 , pp. 81-94
    • Adams, J.H.1    Haller, L.2    Boa, F.Y.3    Dago, F.4    Dago, A.5    Konian, K.6
  • 8
    • 1642410384 scopus 로고    scopus 로고
    • Human African trypanosomiasis of the CNS: current issues and challenges
    • Kennedy P.G.E. Human African trypanosomiasis of the CNS: current issues and challenges. J Clin Invest 2004, 113:496-504.
    • (2004) J Clin Invest , vol.113 , pp. 496-504
    • Kennedy, P.G.E.1
  • 9
    • 0026474526 scopus 로고
    • Astrocyte activation correlates with cytokine production in central nervous system of Trypanosoma brucei brucei-infected mice
    • Hunter C.A., Jennings F.W., Kennedy P.G.E., Murray M. Astrocyte activation correlates with cytokine production in central nervous system of Trypanosoma brucei brucei-infected mice. Lab Invest 1992, 67:635-642.
    • (1992) Lab Invest , vol.67 , pp. 635-642
    • Hunter, C.A.1    Jennings, F.W.2    Kennedy, P.G.E.3    Murray, M.4
  • 10
    • 0025751547 scopus 로고
    • Immunopathology of experimental African sleeping sickness. Detection of cytokine mRNA in the brains of Trypanosoma brucei brucei infected mice
    • Hunter C.A., Gow J.W., Kennedy P.G.E., Jennings F.W., Murray M. Immunopathology of experimental African sleeping sickness. Detection of cytokine mRNA in the brains of Trypanosoma brucei brucei infected mice. Infect Immun 1991, 59:4636-4640.
    • (1991) Infect Immun , vol.59 , pp. 4636-4640
    • Hunter, C.A.1    Gow, J.W.2    Kennedy, P.G.E.3    Jennings, F.W.4    Murray, M.5
  • 11
    • 0036849018 scopus 로고    scopus 로고
    • Microglia as a source and target of cytokine
    • Hanisch U.K. Microglia as a source and target of cytokine. Glia 2002, 40:140-155.
    • (2002) Glia , vol.40 , pp. 140-155
    • Hanisch, U.K.1
  • 12
    • 0027051669 scopus 로고
    • The use of azathioprine to ameliorate post-treatment encephalopathy associated with African trypanosomiasis
    • Hunter C.A., Jennings F.W., Kennedy P.G.E., Murray M. The use of azathioprine to ameliorate post-treatment encephalopathy associated with African trypanosomiasis. Neuropathol Appl Neurobiol 1992, 18:619-625.
    • (1992) Neuropathol Appl Neurobiol , vol.18 , pp. 619-625
    • Hunter, C.A.1    Jennings, F.W.2    Kennedy, P.G.E.3    Murray, M.4
  • 13
    • 0030887855 scopus 로고    scopus 로고
    • A Substance P antagonist, RP-67,580 ameliorates a mouse meningoencephalitic response to Trypanosoma brucei brucei
    • Kennedy P.G.E., Rodgers J., Jennings F.W., Murray M., Leeman S.E., Burke J.M. A Substance P antagonist, RP-67,580 ameliorates a mouse meningoencephalitic response to Trypanosoma brucei brucei. Proc Natl Acad Sci U S A 1997, 94:4167-4170.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 4167-4170
    • Kennedy, P.G.E.1    Rodgers, J.2    Jennings, F.W.3    Murray, M.4    Leeman, S.E.5    Burke, J.M.6
  • 14
    • 0024321758 scopus 로고
    • Trial of prednisolone for prevention of melarsoprol-induced encephalopathy in gambiense sleeping sickness
    • Pepin J., Milord F., Guern C., Mpia B., Ethier L., Mansina D. Trial of prednisolone for prevention of melarsoprol-induced encephalopathy in gambiense sleeping sickness. Lancet 1989, 1:1246-1250.
    • (1989) Lancet , vol.1 , pp. 1246-1250
    • Pepin, J.1    Milord, F.2    Guern, C.3    Mpia, B.4    Ethier, L.5    Mansina, D.6
  • 15
    • 80053451058 scopus 로고    scopus 로고
    • Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasis
    • Rodgers J., Jones A., Gibaud S., Bradley B., McCabe C., Barrett M.P., et al. Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasis. PLoS Negl Trop Dis 2011, 5:e1308.
    • (2011) PLoS Negl Trop Dis , vol.5
    • Rodgers, J.1    Jones, A.2    Gibaud, S.3    Bradley, B.4    McCabe, C.5    Barrett, M.P.6
  • 17
    • 0037471583 scopus 로고    scopus 로고
    • Antioxidant activity of anthocyanins and their aglycons
    • Kahkonen M.P., Heinonen M. Antioxidant activity of anthocyanins and their aglycons. J Agric Food Chem 2003, 51:628-633.
    • (2003) J Agric Food Chem , vol.51 , pp. 628-633
    • Kahkonen, M.P.1    Heinonen, M.2
  • 18
    • 0035868503 scopus 로고    scopus 로고
    • A possible emerging role of phytochemicals in improving age-related neurological dysfunctions: a multiplicity of effects
    • Youdim K.A., Joseph J.A. A possible emerging role of phytochemicals in improving age-related neurological dysfunctions: a multiplicity of effects. Free Radic Biol Med 2001, 30:583-594.
    • (2001) Free Radic Biol Med , vol.30 , pp. 583-594
    • Youdim, K.A.1    Joseph, J.A.2
  • 19
    • 62549159534 scopus 로고    scopus 로고
    • Anthocyanins, antioxidative and antimicrobial properties of American cranberry (Vaccinium macrocarpon Ait.) and their press cakes
    • Viskelis P., Rubiskiene M., Jasutiene I., Sarkinas A., Daubaras R., Cesoniene L. Anthocyanins, antioxidative and antimicrobial properties of American cranberry (Vaccinium macrocarpon Ait.) and their press cakes. J Food Sci 2009, 74:157-161.
    • (2009) J Food Sci , vol.74 , pp. 157-161
    • Viskelis, P.1    Rubiskiene, M.2    Jasutiene, I.3    Sarkinas, A.4    Daubaras, R.5    Cesoniene, L.6
  • 20
    • 0025327523 scopus 로고
    • Ubiquinol-10 is an effective lipid-soluble antioxidant at physiological concentrations
    • Frei B., Kim M.C., Ames B.N. Ubiquinol-10 is an effective lipid-soluble antioxidant at physiological concentrations. Proc Natl Acad Sci U S A 1990, 87:4879-4883.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 4879-4883
    • Frei, B.1    Kim, M.C.2    Ames, B.N.3
  • 21
    • 33646864094 scopus 로고    scopus 로고
    • Complex-1 activity and 18F-DOPA uptake in genetically engineered mouse model of Parkinson's disease and the neuroprotective role of coenzyme-Q10
    • Sharma S.K., El Refaey H., Ebadi M. Complex-1 activity and 18F-DOPA uptake in genetically engineered mouse model of Parkinson's disease and the neuroprotective role of coenzyme-Q10. Brain Res Bull 2006, 70:22-32.
    • (2006) Brain Res Bull , vol.70 , pp. 22-32
    • Sharma, S.K.1    El Refaey, H.2    Ebadi, M.3
  • 23
    • 80054043780 scopus 로고    scopus 로고
    • Characterization of anthocyanins in Kenyan teas: extraction and identification
    • Kerio L.C., Wachira F.N., Wanyoko J.K., Rotich M.K. Characterization of anthocyanins in Kenyan teas: extraction and identification. Food Chem 2012, 131:31-38.
    • (2012) Food Chem , vol.131 , pp. 31-38
    • Kerio, L.C.1    Wachira, F.N.2    Wanyoko, J.K.3    Rotich, M.K.4
  • 24
    • 0000565214 scopus 로고    scopus 로고
    • Characterization of red radish anthocyanins
    • Guisti M.M., Wrolstad R.E. Characterization of red radish anthocyanins. J Food Sci 1996, 61:322-326.
    • (1996) J Food Sci , vol.61 , pp. 322-326
    • Guisti, M.M.1    Wrolstad, R.E.2
  • 25
  • 26
    • 33750331151 scopus 로고    scopus 로고
    • Animal models of CNS (second stage) sleeping sickness
    • AcademicPress, O. Zak, M.A. Sande (Eds.)
    • Gichuki C., Brun R. Animal models of CNS (second stage) sleeping sickness. Handbook of Animal Models of Infection 1999, 795-800. AcademicPress. O. Zak, M.A. Sande (Eds.).
    • (1999) Handbook of Animal Models of Infection , pp. 795-800
    • Gichuki, C.1    Brun, R.2
  • 27
    • 0017168578 scopus 로고
    • A rapid matching method for estimating the host's parasitaemia
    • Herbert W.J., Lumsden W.H.R. A rapid matching method for estimating the host's parasitaemia. Exp Parasitol 1976, 40:427-431.
    • (1976) Exp Parasitol , vol.40 , pp. 427-431
    • Herbert, W.J.1    Lumsden, W.H.R.2
  • 28
    • 0017702421 scopus 로고
    • An improved parasitological technique for the diagnosis of African trypanosomiasis
    • Murray M., Murray P.K., McIntyre W.I.M. An improved parasitological technique for the diagnosis of African trypanosomiasis. Trans R Soc Trop Med Hyg 1977, 71:325-332.
    • (1977) Trans R Soc Trop Med Hyg , vol.71 , pp. 325-332
    • Murray, M.1    Murray, P.K.2    McIntyre, W.I.M.3
  • 29
    • 0014901658 scopus 로고
    • The haematocrit centrifuge technique for the diagnosis of African trypanosomiasis
    • Woo P.T.K. The haematocrit centrifuge technique for the diagnosis of African trypanosomiasis. Acta Trop 1970, 27:384-386.
    • (1970) Acta Trop , vol.27 , pp. 384-386
    • Woo, P.T.K.1
  • 30
    • 34548851693 scopus 로고    scopus 로고
    • Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method
    • Rahman I., Kode A., Biswas S.K. Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method. Nat Protoc 2007, 1:3159-3165.
    • (2007) Nat Protoc , vol.1 , pp. 3159-3165
    • Rahman, I.1    Kode, A.2    Biswas, S.K.3
  • 31
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970, 227:680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 32
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications
    • Towbin H., Staehelin T., Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A 1979, 76:4350-4354.
    • (1979) Proc Natl Acad Sci U S A , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 33
    • 34147196050 scopus 로고    scopus 로고
    • Inhibitory effects of blueberry extract on the production of inflammatory mediators in lipopolysaccharide-activated BV2 microglia
    • Lau F.C., Bielinski D.F., Joseph J.A. Inhibitory effects of blueberry extract on the production of inflammatory mediators in lipopolysaccharide-activated BV2 microglia. J Neurosci Res 2007, 85:1010-1017.
    • (2007) J Neurosci Res , vol.85 , pp. 1010-1017
    • Lau, F.C.1    Bielinski, D.F.2    Joseph, J.A.3
  • 34
    • 21344453327 scopus 로고    scopus 로고
    • Anthocyanidins inhibit cyclooxygenase-2 expression in LPS-evoked macrophages: structure-activity relationship and molecular mechanisms involved
    • Hou D., Yanagita T., Uto T., Masuzaki S., Fujii M. Anthocyanidins inhibit cyclooxygenase-2 expression in LPS-evoked macrophages: structure-activity relationship and molecular mechanisms involved. Biochem Pharmacol 2005, 70:417-425.
    • (2005) Biochem Pharmacol , vol.70 , pp. 417-425
    • Hou, D.1    Yanagita, T.2    Uto, T.3    Masuzaki, S.4    Fujii, M.5
  • 35
    • 0036702860 scopus 로고    scopus 로고
    • Cyanidin 3-O-beta-d-glucoside suppresses nitric oxide production during a zymosan treatment in rats
    • Tsuda T., Horio F., Osawa T. Cyanidin 3-O-beta-d-glucoside suppresses nitric oxide production during a zymosan treatment in rats. J Nutr Sci Vitaminol 2002, 48:305-310.
    • (2002) J Nutr Sci Vitaminol , vol.48 , pp. 305-310
    • Tsuda, T.1    Horio, F.2    Osawa, T.3
  • 36
    • 0021710230 scopus 로고
    • African trypanosomiasis alters prostaglandin production by murine peritoneal macrophages
    • Fierer J., Salmon J.A., Askonas B.A. African trypanosomiasis alters prostaglandin production by murine peritoneal macrophages. Clin Exp Immunol 1984, 58:548-556.
    • (1984) Clin Exp Immunol , vol.58 , pp. 548-556
    • Fierer, J.1    Salmon, J.A.2    Askonas, B.A.3
  • 37
    • 33645549258 scopus 로고    scopus 로고
    • Anti-inflammatory effects of Co-Q10 and colorless carotenoids
    • Fuller B., Smith D., Howerton A., Kern D. Anti-inflammatory effects of Co-Q10 and colorless carotenoids. J Cosmet Dermatol 2005, 5:30-38.
    • (2005) J Cosmet Dermatol , vol.5 , pp. 30-38
    • Fuller, B.1    Smith, D.2    Howerton, A.3    Kern, D.4
  • 38
    • 0027491617 scopus 로고
    • The inactivation of Fe-S cluster containing hydro-lyases by superoxide
    • Flint D.H., Tuminello J.F., Emptage M.H. The inactivation of Fe-S cluster containing hydro-lyases by superoxide. J Biol Chem 1993, 268:22369-22376.
    • (1993) J Biol Chem , vol.268 , pp. 22369-22376
    • Flint, D.H.1    Tuminello, J.F.2    Emptage, M.H.3
  • 39
    • 0029858594 scopus 로고    scopus 로고
    • The tumour promoter arsenite stimulates AP-1 activity by inhibiting a JNK phosphatase
    • Cavigelli M., Li W.W., Lin A., Su B., Yoshioka K., Karin M. The tumour promoter arsenite stimulates AP-1 activity by inhibiting a JNK phosphatase. Eur Mol Biol Org J 1996, 15:6269-6279.
    • (1996) Eur Mol Biol Org J , vol.15 , pp. 6269-6279
    • Cavigelli, M.1    Li, W.W.2    Lin, A.3    Su, B.4    Yoshioka, K.5    Karin, M.6
  • 40
    • 84860153566 scopus 로고    scopus 로고
    • Induction of oxidative stress in Trypanosoma brucei by the anti-trypanosomal dihydroquinoline OSU-40
    • He S., Dayton A., Kuppusamy A., Werbovetz K.A., Drew M.E. Induction of oxidative stress in Trypanosoma brucei by the anti-trypanosomal dihydroquinoline OSU-40. Antimicrob Agents Chemother 2012, 56:2428-2434.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 2428-2434
    • He, S.1    Dayton, A.2    Kuppusamy, A.3    Werbovetz, K.A.4    Drew, M.E.5
  • 41
    • 79955514890 scopus 로고    scopus 로고
    • Potential role of some nutraceuticals in the regression of Alzheimer's disease in an experimental animal model
    • Ahmed H.H., Shousha W.G., Hussien R.M., Farrag A.R.H. Potential role of some nutraceuticals in the regression of Alzheimer's disease in an experimental animal model. Turk J Med Sci 2011, 41:455-466.
    • (2011) Turk J Med Sci , vol.41 , pp. 455-466
    • Ahmed, H.H.1    Shousha, W.G.2    Hussien, R.M.3    Farrag, A.R.H.4
  • 42
    • 77954141949 scopus 로고    scopus 로고
    • Coenzyme-Q10 treatment ameliorates acute cisplatin nephrotoxicity in mice
    • Fouad A.A., Al-Sultan A.I., Refaie S.M., Yacoubi M.T. Coenzyme-Q10 treatment ameliorates acute cisplatin nephrotoxicity in mice. Toxicology 2010, 274:49-56.
    • (2010) Toxicology , vol.274 , pp. 49-56
    • Fouad, A.A.1    Al-Sultan, A.I.2    Refaie, S.M.3    Yacoubi, M.T.4
  • 43
    • 34248161002 scopus 로고    scopus 로고
    • Coenzyme Q, oxidative stress and aging
    • Sohal R.S., Forster M.J. Coenzyme Q, oxidative stress and aging. Mitochondrion 2007, 7:103-111.
    • (2007) Mitochondrion , vol.7 , pp. 103-111
    • Sohal, R.S.1    Forster, M.J.2
  • 44
    • 56249128541 scopus 로고    scopus 로고
    • Mechanism of the neuroprotective role of coenzyme-Q10 with or without l-dopa in rotenone-induced parkinsonism
    • Abdin A.A., Hamouda H.E. Mechanism of the neuroprotective role of coenzyme-Q10 with or without l-dopa in rotenone-induced parkinsonism. Neuropharmacology 2008, 55:1340-1346.
    • (2008) Neuropharmacology , vol.55 , pp. 1340-1346
    • Abdin, A.A.1    Hamouda, H.E.2
  • 45
    • 0028631186 scopus 로고
    • Evidence for a protective effect of endogenous ubiquinol against oxidative damage to mitochondrial protein and DNA during lipid peroxidation
    • Forsmark-Andree P., Ernster L. Evidence for a protective effect of endogenous ubiquinol against oxidative damage to mitochondrial protein and DNA during lipid peroxidation. Mol Aspects Med 1994, 15:73-81.
    • (1994) Mol Aspects Med , vol.15 , pp. 73-81
    • Forsmark-Andree, P.1    Ernster, L.2
  • 46
    • 84893407803 scopus 로고    scopus 로고
    • Attenuation of t- Butylhydroperoxide induced oxidative stress in HEK 293 WT cells by tea catechins and anthocyanins
    • Kerio L.C., Bend J.R., Wachira F.N., Wanyoko J.K., Rotich M.K. Attenuation of t- Butylhydroperoxide induced oxidative stress in HEK 293 WT cells by tea catechins and anthocyanins. J Toxicol Environ Health 2011, 14:367-375.
    • (2011) J Toxicol Environ Health , vol.14 , pp. 367-375
    • Kerio, L.C.1    Bend, J.R.2    Wachira, F.N.3    Wanyoko, J.K.4    Rotich, M.K.5
  • 47
    • 0021877040 scopus 로고
    • Developmental cycles and biology of pathogenic trypanosomes
    • Vickerman K. Developmental cycles and biology of pathogenic trypanosomes. Br Med Bull 1985, 41:105-114.
    • (1985) Br Med Bull , vol.41 , pp. 105-114
    • Vickerman, K.1
  • 48
    • 84893423331 scopus 로고    scopus 로고
    • Pathogenicity of bloodstream and cerebrospinal fluid forms of Trypanosoma brucei rhodesiense in Swiss white mice
    • Ndung'u K., Ngotho M., Kinyua J., Kagira J., Guya S., Ndung'u J., et al. Pathogenicity of bloodstream and cerebrospinal fluid forms of Trypanosoma brucei rhodesiense in Swiss white mice. Afr J Health Sci 2008, 15:34-41.
    • (2008) Afr J Health Sci , vol.15 , pp. 34-41
    • Ndung'u, K.1    Ngotho, M.2    Kinyua, J.3    Kagira, J.4    Guya, S.5    Ndung'u, J.6
  • 51
    • 0002536960 scopus 로고
    • Hematology of African trypanosomiasis
    • CRC Press, Boca Raton, Florida, I. Tizard (Ed.)
    • Jenkins G.C., Facer C.A. Hematology of African trypanosomiasis. Immunology and Pathogenesis of Trypanosomiasis 1985, 13-44. CRC Press, Boca Raton, Florida. I. Tizard (Ed.).
    • (1985) Immunology and Pathogenesis of Trypanosomiasis , pp. 13-44
    • Jenkins, G.C.1    Facer, C.A.2
  • 52
    • 77953465939 scopus 로고    scopus 로고
    • Green tea-EGCG reduces GFAP associated neuronal loss in HIV-1 Tat transgenic mice
    • Rrapo E., Zhu Y., Tian J., Hou H., Smith A., Fernandez F., et al. Green tea-EGCG reduces GFAP associated neuronal loss in HIV-1 Tat transgenic mice. Am J Transl Res 2009, 1:72-79.
    • (2009) Am J Transl Res , vol.1 , pp. 72-79
    • Rrapo, E.1    Zhu, Y.2    Tian, J.3    Hou, H.4    Smith, A.5    Fernandez, F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.