Late stage infection in sleeping sickness

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Wolburg, Hartwig ^a   Mogk, Stefan ^a   Acker, Sven ^a   Frey, Claudia ^a   Meinert, Monika ^a   Schönfeld, Caroline ^a   Lazarus, Michael ^b   Urade, Yoshihiro ^b   Kubata, Bruno Kilunga ^c   Duszenko, Michael ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b OSAKA BIOSCIENCE INSTITUTE   (Japan)

^c African Union/New Partnership for Africa's   (Kenya)

Author keywords

[No Author keywords available]

Indexed keywords

AFRICAN TRYPANOSOMIASIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD VESSEL; BRAIN INFECTION; BRAIN VENTRICLE; CEREBROSPINAL FLUID; CHOROID PLEXUS; CONTROLLED STUDY; ELECTRON MICROSCOPY; EPITHELIUM CELL; NONHUMAN; PARASITE SURVIVAL; RAT; ANIMAL; BLOOD; BRAIN; CULTURE MEDIUM; ISOLATION AND PURIFICATION; PARASITOLOGY; PATHOLOGY; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY; TRYPANOSOMA BRUCEI; WISTAR RAT;

RODENTIA;

ANIMALS; BRAIN; CULTURE MEDIA; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; RATS; RATS, WISTAR; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMIASIS, AFRICAN;

EID: 84858971155     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0034304     Document Type: Article

References (57)

1. Cox F, (2004) History of sleeping sickness (African trypanosomiasis). Infectious disease clinics of North America 18: 231.
2. Steverding D, (2008) The history of African trypanosomiasis. Parasites & Vectors 1: 3.
3. WHO (2011) African trypanosomiasis (sleeping sickness).
4. Kibona SN, Matemba L, Kaboya JS, Lubega GW, (2006) Drug-resistance of Trypanosoma b. rhodesiense isolates from Tanzania. Tropical medicine & international health: TM & IH 11: 144-155.
5. Brun R, Blum J, Chappuis F, Burri C, (2010) Human African trypanosomiasis. The Lancet 375: 148-159.
6. Cross GA, Wirtz LE, Navarro M, (1998) Regulation of vsg expression site transcription and switching in Trypanosoma brucei. Molecular and biochemical parasitology 91: 77-91.
7. Turner CM, (1997) The rate of antigenic variation in fly-transmitted and syringe-passaged infections of Trypanosoma brucei. FEMS Microbiology Letters 153: 227-231.
8. Leggat PA, (2003) Essentials of Tropical Infectious Diseases 1st Ed.; Richard L. Guerrant, David H. Walker, Peter F. Weller (Eds.); Churchill Livingstone, Philadelphia, PA, 2001, xxiv+664 pages, with illus, hardcover, ISBN 0-443-07909-9 (US$ 145.00). Travel medicine and infectious disease 1: 137-138.
9. Greenwood BM, Whittle HC, (1980) The pathogenesis of sleeping sickness. Transactions of the Royal Society of Tropical Medicine and Hygiene 74: 716-725.
10. Kreier J, (1977) Parasitic Protozoa. 1: 205-208.
11. Bruce D, (1895) Preliminary Report on Tsetse Fly Disease or Nagana in Zululand Durban Bennet & Davis.
12. Castellani A, (1903) Some Observations on the Morphology of the Trypanosoma Found in Sleeping Sickness. British medical journal 1: 1431-1432.
13. Haag J, O'HUigin C, Overath P, (1998) The molecular phylogeny of trypanosomes: evidence for an early divergence of the Salivaria. Molecular and biochemical parasitology 91: 37-49.
14. Hayaishi O, Urade Y, Eguchi N, Huang ZL, (2004) Genes for prostaglandin d synthase and receptor as well as adenosine A2A receptor are involved in the homeostatic regulation of nrem sleep. Archives italiennes de biologie 142: 533-539.
15. Pentreath V, (1995) Trypanosomiasis and the nervous system:: Pathology and immunology. Transactions of the Royal Society of Tropical Medicine and Hygiene 89: 9-15.
16. Kubata BK, Duszenko M, Martin KS, Urade Y, (2007) Molecular basis for prostaglandin production in hosts and parasites. Trends Parasitol 23: 325-331.
17. Duszenko M, Figarella K, Macleod ET, Welburn SC, (2006) Death of a trypanosome: a selfish altruism. Trends Parasitol 22: 536-542.
18. Mulenga C, Mhlanga JD, Kristensson K, Robertson B, (2001) Trypanosoma brucei brucei crosses the blood-brain barrier while tight junction proteins are preserved in a rat chronic disease model. Neuropathol Appl Neurobiol 27: 77-85.
19. Schmidt H, (1983) The pathogenesis of trypanosomiasis of the CNS. Studies on parasitological and neurohistological findings in trypanosoma rhodesiense infected vervet monkeys. Virchows Archiv A, Pathological anatomy and histopathology 399: 333-343.
20. Poltera AA, Hochmann A, Rudin W, Lambert PH, (1980) Trypanosoma brucei brucei: a model for cerebral trypanosomiasis in mice-an immunological, histological and electronmicroscopic study. Clinical and experimental immunology 40: 496-507.
21. Schmidt H, Bafort JM, (1985) African trypanosomiasis: treatment-induced invasion of brain and encephalitis. The American journal of tropical medicine and hygiene 34: 64-68.
22. Rubin LL, Staddon JM, (1999) The cell biology of the blood-brain barrier. Annual review of neuroscience 22: 11-28.
23. Wolburg H, Paulus W, (2010) Choroid plexus: biology and pathology. Acta neuropathologica 119: 75-88.
24. Wolburg H, Wolburg-Buchholz K, Liebner S, Engelhardt B, (2001) Claudin-1, claudin-2 and claudin-11 are present in tight junctions of choroid plexus epithelium of the mouse. Neuroscience letters 307: 77-80.
25. Denninger V, Koopmann R, Muhammad K, Barth T, Bassarak B, et al. (2008) Kinetoplastida: model organisms for simple autophagic pathways? Methods Enzymol 451: 373-408.
26. Figarella K, Rawer M, Uzcategui NL, Kubata BK, Lauber K, et al. (2005) Prostaglandin D2 induces programmed cell death in Trypanosoma brucei bloodstream form. Cell Death Differ 12: 335-346.
27. Figarella K, Uzcategui NL, Beck A, Schoenfeld C, Kubata BK, et al. (2006) Prostaglandin-induced programmed cell death in Trypanosoma brucei involves oxidative stress. Cell Death Differ 13: 1802-1814.
28. Lentner C, (1981) Geigy Scientific Tables. Ciby-Geigy, Basle 1.
29. Frankmann S, (1987) (1987) A new approach to repeated sampling of csf from the anesthetized rat.
30. Hirumi H, Hirumi K, (1994) Axenic culture of African trypanosome bloodstream forms. Parasitol Today 10: 80-84.
31. Iadecola C, (2004) Neurovascular regulation in the normal brain and in Alzheimer's disease. Nature reviews Neuroscience 5: 347-360.
32. Kwee RM, Kwee TC, (2007) Virchow-Robin spaces at MR imaging. Radiographics: a review publication of the Radiological Society of North America, Inc 27: 1071-1086.
33. Zhang ET, Inman CB, Weller RO, (1990) Interrelationships of the pia mater and the perivascular (Virchow-Robin) spaces in the human cerebrum. Journal of anatomy 170: 111-123.
34. Morse DE, Low FN, (1972) The fine structure of the pia mater of the rat. The American journal of anatomy 133: 349-367.
35. Ransohoff RM, Kivisakk P, Kidd G, (2003) Three or more routes for leukocyte migration into the central nervous system. Nature reviews Immunology 3: 569-581.
36. Kristensson K, Nygard M, Bertini G, Bentivoglio M, (2010) African trypanosome infections of the nervous system: parasite entry and effects on sleep and synaptic functions. Prog Neurobiol 91: 152-171.
37. Onoe H, Ueno R, Fujita I, Nishino H, Oomura Y, et al. (1988) Prostaglandin D2, a cerebral sleep-inducing substance in monkeys. Proceedings of the National Academy of Sciences of the United States of America 85: 4082-4086.
38. Pentreath VW, Rees K, Owolabi OA, Philip KA, Doua F, (1990) The somnogenic T lymphocyte suppressor prostaglandin D2 is selectively elevated in cerebrospinal fluid of advanced sleeping sickness patients. Transactions of the Royal Society of Tropical Medicine and Hygiene 84: 795-799.
39. Ormerod WE, Hussein MS, (1986) The ventricular ependyma of mice infected with Trypanosoma brucei. Transactions of the Royal Society of Tropical Medicine and Hygiene 80: 626-633.
40. Ferguson MA, Low MG, Cross GA, (1985) Glycosyl-sn-1,2-dimyristylphosphatidylinositol is covalently linked to Trypanosoma brucei variant surface glycoprotein. The Journal of biological chemistry 260: 14547-14555.
41. Pentreath VW, Owolabi AO, Doua F, (1992) Survival of Trypanosoma brucei brucei in cerebrospinal fluid. Annals of tropical medicine and parasitology 86: 29-34.
42. Wastling SL, Welburn SC, (2011) Diagnosis of human sleeping sickness: sense and sensitivity. Trends in parasitology 27: 394-402.
43. Rodgers J, McCabe C, Gettinby G, Bradley B, Condon B, et al. (2011) Magnetic resonance imaging to assess blood-brain barrier damage in murine trypanosomiasis. The American journal of tropical medicine and hygiene 84: 344-350.
44. Lyck R, Reiss Y, Gerwin N, Greenwood J, Adamson P, et al. (2003) T-cell interaction with ICAM-1/ICAM-2 double-deficient brain endothelium in vitro: the cytoplasmic tail of endothelial ICAM-1 is necessary for transendothelial migration of T cells. Blood 102: 3675-3683.
45. Masocha W, Rottenberg ME, Kristensson K, (2007) Migration of African trypanosomes across the blood-brain barrier. Physiol Behav 92: 110-114.
46. Engelhardt B, Wolburg H, (2004) Mini-review: Transendothelial migration of leukocytes: through the front door or around the side of the house? European journal of immunology 34: 2955-2963.
47. Patzold U, Haller P, Baruth B, Liman W, Deicher H, (1980) Immune complexes in multiple sclerosis: relation to clinical pattern. Journal of neurology 222: 249-260.
48. Lambert PH, Berney M, Kazyumba G, (1981) Immune complexes in serum and in cerebrospinal fluid in African trypanosomiasis. Correlation with polyclonal B cell activation and with intracerebral immunoglobulin synthesis. The Journal of clinical investigation 67: 77-85.
49. Claes F, Vodnala SK, van Reet N, Boucher N, Lunden-Miguel H, et al. (2009) Bioluminescent imaging of Trypanosoma brucei shows preferential testis dissemination which may hamper drug efficacy in sleeping sickness. PLoS neglected tropical diseases 3: e486.
50. Wolburg H, Lippoldt A, (2002) Tight junctions of the blood-brain barrier: development, composition and regulation. Vascular pharmacology 38: 323-337.
51. Yang Y, Hill JW, Rosenberg GA, (2011) Multiple roles of metalloproteinases in neurological disorders. Progress in molecular biology and translational science 99: 241-263.
52. de Sousa KP, Atouguia J, Silva MS, (2010) Partial biochemical characterization of a metalloproteinase from the bloodstream forms of Trypanosoma brucei brucei parasites. The protein journal 29: 283-289.
53. Black SJ, Hewett RS, Sendashonga CN, (1982) Trypanosoma brucei variable surface antigen is released by degenerating parasites but not by actively dividing parasites. Parasite immunology 4: 233-244.
54. Lanham SM, (1968) Separation of trypanosomes from the blood of infected rats and mice by anion-exchangers. Nature 218: 1273-1274.
55. Paxinos GeW, C, (1998) The Rat Brain in Stereotaxic Coordinates Academic Press.
56. Wewer C, Seibt A, Wolburg H, Greune L, Schmidt MA, et al. (2011) Transcellular migration of neutrophil granulocytes through the blood-cerebrospinal fluid barrier after infection with Streptococcus suis. Journal of neuroinflammation 8: 51.
57. Osterauer R, Marschner L, Betz O, Gerberding M, Sawasdee B, et al. (2010) Turning snails into slugs: induced body plan changes and formation of an internal shell. Evolution & development 12: 474-483.