Modulation of pyridinium cationic lipid-DNA complex properties by pyridinium gemini surfactants and its impact on lipoplex transfection properties

Molecular Pharmaceutics

Volumn 11, Issue 2, 2014, Pages 545-559

  Sharma, Vishnu Dutt ^a   Lees, Julia ^a   Hoffman, Nicholas E ^b   Brailoiu, Eugen ^b   Madesh, Muniswamy ^b   Wunder, Stephanie L ^c   Ilies, Marc A ^a  

^a TEMPLE UNIVERSITY SCHOOL OF PHARMACY   (United States)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Temple University   (United States)

Author keywords

cationic lipid; gemini surfactant; lipoplex; pyridinium; synergy; transfection

Indexed keywords

LIPOPLEX; PLASMID DNA; PYRIDINIUM DERIVATIVE; SURFACTANT; CATION; DNA; LIPID;

ARTICLE; BILAYER MEMBRANE; CELL VIABILITY ASSAY; CHEMICAL COMPOSITION; CYTOTOXICITY TEST; ELECTRICITY; ELECTROPHORETIC MOBILITY; GENETIC TRANSFECTION; INTERNALIZATION; LIGHT SCATTERING; LIPID BILAYER; MOLECULAR DYNAMICS; MOLECULAR MECHANICS; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; ZETA POTENTIAL; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; GENE TRANSFER; HUMAN; TUMOR CELL LINE;

CATIONS; CELL LINE, TUMOR; CELL SURVIVAL; DNA; GENE TRANSFER TECHNIQUES; HUMANS; LIPIDS; MOLECULAR STRUCTURE; PYRIDINIUM COMPOUNDS; SURFACE-ACTIVE AGENTS; TRANSFECTION;

EID: 84893334943     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp4005035     Document Type: Article

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