Time-series pattern of gene expression profile in gentamycin-induced nephrotoxicity

Toxicology Mechanisms and Methods

Volumn 24, Issue 2, 2014, Pages 142-150

  Qiu, Yunliang ^a,b   Hong, Min ^a   Li, Hua ^a   Tang, Naping ^a   Ma, Jing ^a   Hsu, Ching Hung ^a   Dong, Wenxin ^b  

^a National Shanghai Center for New Drug Safety Evaluation and Research   (China)

^b China State Institute of Pharmaceutical Industry   (China)

Author keywords

Gene expression; Gentamycin; Microarray; Nephrotoxicity; Time series

Indexed keywords

GENTAMICIN; KIDNEY INJURY MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPSY; FEMALE; GENE EXPRESSION PROFILING; HISTOPATHOLOGY; IMMUNE RESPONSE; MALE; MICROARRAY ANALYSIS; NEPHROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; TIME SERIES ANALYSIS; URINALYSIS;

ANIMALS; ANTI-BACTERIAL AGENTS; BASE SEQUENCE; CELL ADHESION MOLECULES; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION PROFILING; GENTAMICINS; KIDNEY; MALE; PRINCIPAL COMPONENT ANALYSIS; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84893315882     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.3109/15376516.2013.869780     Document Type: Article

References (30)

1. Amin RP, Vickers AE, Sistare F, et al. (2004). Identification of putative gene based markers of renal toxicity. Environ Health Perspect 112: 465-79.
2. Bar-joseph Z, Gitter A, Simon I. (2012). Studying and modelling dynamic biological processes using time-series gene expression data. Nat Rev Genet 13:552-64.
3. Bonventre JV. (2009). Kidney injury molecule-1 (kim-1): a urinary biomarker and much more. Nephrol Dial Transplant 24:3265-8.
4. Boverhof DR, Burgoon LD, Tashiro C, et al. (2006). Comparative toxicogenomic analysis of the hepatotoxic effects of tcdd in sprague dawley rats and c57bl/6 mice. Toxicol Sci 94:398-416.
5. Hanna MH, Segar JL, Teesch LM, et al. (2013). Urinary metabolomic markers of aminoglycoside nephrotoxicity in newborn rats. Pediatr Res 73:585-91.
6. Hoitsma AJ, Wetzels JF, Koene RA. (1991). Drug-induced nephrotoxicity. Aetiology, clinical features and management. Drug Saf 6: 131-47.
7. Hosohata K, Ando H, Fujiwara Y, Fujimura A. (2011). Vanin-1: a potential biomarker for nephrotoxicant-induced renal injury. Toxicology 290:82-8.
8. Huang Q, Dunn II RT, Jayadev S, et al. (2001). Assessment of cisplatininduced nephrotoxicity by microarray technology. Toxicol Sci 63: 196-207.
9. Kondo C, Aoki M, Yamamoto E, et al. (2012). Predictive genomic biomarkers for drug-induced nephrotoxicity in mice. J Toxicol Sci 37: 723-37.
10. Liu J-R, Jin B, Xie Y-J, et al. (2009). Investigation on the characteristics of a new high frequency three-way proportional pressure reducing valve in variable valve system of automobile engine. Ijems 16:7-13.
11. Minowa Y, Kondo C, Uehara T, et al. (2012). Toxicogenomic multigene biomarker for predicting the future onset of proximal tubular injury in rats. Toxicology 297:47-56.
12. Morin JP, Viotte G, Vandewalle A, et al. (1980). Gentamicin-induced nephrotoxicity: a cell biology approach. Kidney Int 18:583-90.
13. Nuwaysir EF, Bittner M, Trent J, et al. (1999). Microarrays and toxicology: the advent of toxicogenomics. Mol Carcinog 24:153-9.
14. Ozaki N, Matheis KA, Gamber M, et al. (2010). Identification of genes involved in gentamicin-induced nephrotoxicity in rats - a toxicogenomic investigation. Exp Toxicol Pathol 62:555-66.
15. Patel MB, Deshpande S, Shah G. (2011). Evaluation of efficacy of vitamin E and n-acetyl cysteine in gentamicin-induced nephrotoxicity in rats. Ren Fail 33:341-7.
16. Quiros Y, Vicente-vicente L, Morales AI, et al. (2010). An integrative overview on the mechanisms underlying the renal tubular cytotoxicity of gentamicin. Toxicol Sci 119:245-56.
17. Rached E, Hoffmann D, Blumbach K, et al. (2008). Evaluation of putative biomarkers of nephrotoxicity after exposure to ochratoxin a in vivo and in vitro. Toxicol Sci 103:371-81.
18. Robinson JF, Pennings JL, Piersma AH. (2012). A review of toxicogenomic approaches in developmental toxicology. Methods Mol Biol 889:347-71.
19. Schreuder MF, Bueters RR, Huigen MC, et al. (2010). Effect of drugs on renal development. Clin J Am Soc Nephrol 6:212-17.
20. Simmons PT, Portier CJ. (2002). Toxicogenomics: the new frontier in risk analysis. Carcinogenesis 23:903-5.
21. Sinha V, Vence LM, Salahudeen AK. (2013). Urinary tubular proteinbased biomarkers in the rodent model of cisplatin nephrotoxicity: a comparative analysis of serum creatinine, renal histology, and urinary kim-1, ngal, and nag in the initiation, maintenance, and recovery phases of acute kidney injury. J Investig Med 61:564-8.
22. Suter L, Babiss LE, Wheeldon EB. (2004). Toxicogenomics in predictive toxicology in drug development. Chem Biol 11:161-71.
23. Uehara T, Kondo C, Morikawa Y, et al. (2013). Toxicogenomic biomarkers for renal papillary injury in rats. Toxicology 303:1-8.
24. Vaidya VS, Ozer JS, Dieterle F, et al. (2010). Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies. Nat Biotechnol 28:478-85.
25. Van vliet E. (2011). Current standing and future prospects for the technologies proposed to transform toxicity testing in the 21st century Altex 28 17-44.
26. Walker PD, Barri Y, Shah SV. (1999). Oxidant mechanisms in gentamicin nephrotoxicity. Ren Fail 21:433-42.
27. Wang EJ, Snyder RD, Fielden MR, et al. (2008). Validation of putative genomic biomarkers of nephrotoxicity in rats. Toxicology 246: 91-100.
28. Yaman I, Balikci E. (2010). Protective effects of Nigella sativa against gentamicin-induced nephrotoxicity in rats. Exp Toxicol Pathol 62: 183-90.
29. Yosef N, Regev A. (2011). Impulse control: temporal dynamics in gene transcription. Cell 144:886-96.
30. Zhang W, Roederer MW, Chen WQ, et al. (2012). Pharmacogenetics of drugs withdrawn from the market. Pharmacogenomics 13:223-31.