Mechanical stress induces pre-B-cell colony-enhancing factor/NAMPT expression via epigenetic regulation by miR-374a and miR-568 in human lung endothelium

American Journal of Respiratory Cell and Molecular Biology

Volumn 50, Issue 2, 2014, Pages 409-418

  Adyshev, Djanybek M ^a   Ramamoorthi Elangovan, Venkateswaran ^a   Moldobaeva, Nurgul ^a   Mapes, Brandon ^a   Sun, Xiaoguang ^a   Garcia, Joe G N ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

ARDS; Endothelial cells; MIRNA; PBEF NAMPT; Ventilator induced lung injury

Indexed keywords

ANTAGOMIR; LIPOPOLYSACCHARIDE; MICRORNA; MICRORNA 374A; MICRORNA 568; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ADULT RESPIRATORY DISTRESS SYNDROME; ARTICLE; BLOOD VESSEL PERMEABILITY; COMPARATIVE STUDY; CONTROLLED STUDY; ENDOTHELIUM CELL; EPIGENETICS; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; LUCIFERASE ASSAY; LUNG ENDOTHELIUM; MECHANICAL STRESS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA BINDING; RNA FOLDING; TRANSCRIPTION REGULATION; VENTILATOR INDUCED LUNG INJURY; WESTERN BLOTTING;

CYTOKINES; ENDOTHELIUM; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; LIPOPOLYSACCHARIDES; LUNG; MICRORNAS; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; RESPIRATORY DISTRESS SYNDROME, ADULT; RNA, MESSENGER; STRESS, MECHANICAL; VENTILATOR-INDUCED LUNG INJURY;

EID: 84893231063     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2013-0292OC     Document Type: Article

References (55)

1. Levitt JE, Matthay MA. Treatment of acute lung injury: historical perspective and potential future therapies. Semin Respir Crit Care Med 2006;27:426-437.
2. Leaver SK, Evans TW. Acute respiratory distress syndrome. BMJ 2007; 335:389-394.
3. Rubenfeld GD, Caldwell E, Peabody E, Weaver J, Martin DP, Neff M, Stern EJ, Hudson LD. Incidence and outcomes of acute lung injury. N Engl J Med 2005;353:1685-1693.
4. Ognjanovic S, Bao S, Yamamoto SY, Garibay-Tupas J, Samal B, Bryant- Greenwood GD. Genomic organization of the gene coding for human pre-b-cell colony enhancing factor and expression in human fetal membranes. J Mol Endocrinol 2001;26:107-117.
5. Rongvaux A, Shea RJ, Mulks MH, Gigot D, Urbain J, Leo O, Andris F. Pre-b-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis. Eur J Immunol 2002;32:3225-3234.
6. Sommer G, Garten A, Petzold S, Beck-Sickinger AG, Bluher M, Stumvoll M, Fasshauer M. Visfatin/PBEF/Nampt: structure, regulation and potential function of a novel adipokine. Clin Sci (Lond) 2008;115:13-23.
7. Ye SQ, Simon BA, Maloney JP, Zambelli-Weiner A, Gao L, Grant A, Easley RB, McVerry BJ, Tuder RM, Standiford T, et al. Pre-b-cell colony-enhancing factor as a potential novel biomarker in acute lung injury. Am J Respir Crit Care Med 2005;171:361-370.
8. Hug C, Lodish HF. Medicine. Visfatin: a new adipokine. Science 2005; 307:366-367.
9. Hong SB, Huang Y, Moreno-Vinasco L, Sammani S, Moitra J, Barnard JW, Ma SF, Mirzapoiazova T, Evenoski C, Reeves RR, et al. Essential role of pre-b-cell colony enhancing factor in ventilator-induced lung injury. Am J Respir Crit Care Med 2008;178:605-617.
10. Bajwa EK, Yu CL, Gong MN, Thompson BT, Christiani DC. Pre-b-cell colony-enhancing factor gene polymorphisms and risk of acute respiratory distress syndrome. Crit Care Med 2007;35:1290-1295.
11. Ye SQ, Zhang LQ, Adyshev D, Usatyuk PV, Garcia AN, Lavoie TL, Verin AD, Natarajan V, Garcia JG. Pre-b-cell-colony-enhancing factor is critically involved in thrombin-induced lung endothelial cell barrier dysregulation. Microvasc Res 2005;70:142-151.
12. Jia SH, Li Y, Parodo J, Kapus A, Fan L, Rotstein OD, Marshall JC. Pre-b cell colony-enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis. J Clin Invest 2004; 113:1318-1327.
13. Liu P, Li H, Cepeda J, Zhang LQ, Cui X, Garcia JG, Ye SQ. Critical role of PBEF expression in pulmonary cell inflammation and permeability. Cell Biol Int 2009;33:19-30.
14. Li H, Liu P, Cepeda J, Fang D, Easley RB, Simon BA, Zhang LQ, Ye SQ. Augmentation of pulmonary epithelial cell IL-8 expression and permeability by pre-b-cell colony enhancing factor. J Inflamm (Lond) 2008;5:15.
15. Dahl TB, Yndestad A, Skjelland M, Oie E, Dahl A, Michelsen A, Damas JK, Tunheim SH, Ueland T, Smith C, et al. Increased expression of visfatin in macrophages of human unstable carotid and coronary atherosclerosis: possible role in inflammation and plaque destabilization. Circulation 2007;115:972-980.
16. Tomankova T, Petrek M, Kriegova E. Involvement of microRNAs in physiological and pathological processes in the lung. Respir Res 2010;11:159.
17. Sokolov MV, Panyutin IV, Neumann RD. Unraveling the global microRNAome responses to ionizing radiation in human embryonic stem cells. PLoS ONE 2012;7:e31028.
18. Ji F, Lv X, Jiao J. The role of micrornas in neural stem cells and neurogenesis. J Genet Genomics 2013;40:61-66.
19. Zhou T, Garcia JG, Zhang W. Integrating microRNAs into a system biology approach to acute lung injury. Transl Res 2011;157: 180-190.
20. Ranjha R, Paul J. Micro-RNAs in inflammatory diseases and as a link between inflammation and cancer. Inflamm Res 2013;62: 343-355.
21. Kornfeld JW, Baitzel C, Konner AC, Nicholls HT, Vogt MC, Herrmanns K, Scheja L, Haumaitre C, Wolf AM, Knippschild U, et al. Obesityinduced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b. Nature 2013;494:111-115.
22. Li N, Zhong X, Lin X, Guo J, Zou L, Tanyi JL, Shao Z, Liang S, Wang LP, Hwang WT, et al. Lin-28 homologue A (LIN28A) promotes cell cycle progression via the regulation of cyclin-dependent kinase 2 (CDK2), cyclin D1 (CCND1), and cell division cycle 25 homolog A (CDC25A) expression in cancer. J Biol Chem 2012;287:17386-17397.
23. Grosso S, Doyen J, Parks SK, Bertero T, Paye A, Cardinaud B, Gounon P, Lacas-Gervais S, Noel A, Pouyssegur J, et al. MiR-210 promotes a hypoxic phenotype and increases radioresistance in human lung cancer cell lines. Cell Death Dis 2013;4:e544.
24. Creemers EE, Tijsen AJ, Pinto YM. Circulating microRNAs: Novel biomarkers and extracellular communicators in cardiovascular disease? Circ Res 2012;110:483-495.
25. Kohlstedt K, Trouvain C, Boettger T, Shi L, Fisslthaler B, Fleming I. The AMP-activated protein kinase regulates endothelial cell angiotensin-converting enzyme expression via p53 and the posttranscriptional regulation of microRNA-143/145. Circ Res 2013; 112:1150-1158.
26. Zhao JL, Rao DS, Boldin MP, Taganov KD, O'Connell RM, Baltimore D. NF-kappaB dysregulation in microRNA-146a-deficient mice drives the development of myeloid malignancies. Proc Natl Acad Sci USA 2011;108:9184-9189.
27. Persengiev SP. MiRNAs at the crossroad between hematopoietic malignancies and autoimmune pathogenesis. Discov Med 2012;13: 211-221.
28. Liu N, Landreh M, Cao K, Abe M, Hendriks GJ, Kennerdell JR, Zhu Y, Wang LS, Bonini NM. The microRNA miR-34 modulates ageing and neurodegeneration in drosophila. Nature 2011;482:519-523.
29. Garcia JG, Liu F, Verin AD, Birukova A, Dechert MA, Gerthoffer WT, Bamburg JR, English D. Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement. J Clin Invest 2001;108:689-701.
30. Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005;120:15-20.
31. Grimson A, Farh KK, Johnston WK, Garrett-Engele P, Lim LP, Bartel DP. MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol Cell 2007;27:91-105.
32. Betel D, Wilson M, Gabow A, Marks DS, Sander C. The microRNA.Org resource: targets and expression. Nucleic Acids Res 2008;36: D149-D153.
33. Maragkakis M, Reczko M, Simossis VA, Alexiou P, Papadopoulos GL, Dalamagas T, Giannopoulos G, Goumas G, Koukis E, Kourtis K, et al. Diana-micro t web server: elucidating microrna functions through target prediction. Nucleic Acids Res 2009;37:W273-W276.
34. Adyshev DM, Moldobaeva NK, Elangovan VR, Garcia JG, Dudek SM. Differential involvement of ezrin/radixin/moesin proteins in sphingosine 1-phosphate-induced human pulmonary endothelial cell barrier enhancement. Cell Signal 2011;23:2086-2096.
35. Mitra S, Sammani S, Wang T, Boone DL, Meyer NJ, Dudek SM, Moreno-Vinasco L, Garcia JG, Jacobson Jr. Role of growth arrest and DNA damage-inducible alpha in Akt phosphorylation and ubiquitination after mechanical stress-induced vascular injury. Am J Respir Crit Care Med 2011;184:1030-1040.
36. Gao L, Grant A, Halder I, Brower R, Sevransky J, Maloney JP, Moss M, Shanholtz C, Yates CR, Meduri GU, et al. Novel polymorphisms in the myosin light chain kinase gene confer risk for acute lung injury. Am J Respir Cell Mol Biol 2006;34:487-495.
37. Adyshev DM, Moldobaeva N, Mapes B, Elangovan V, Garcia JG. MicroRNA regulation of non-muscle myosin light chain kinase (nmmlck) expression in human lung endothelium. Am J Respir Cell Mol Biol 2013;49:58-66.
38. Bartel DP. Micrornas: target recognition and regulatory functions. Cell 2009;136:215-233.
39. Witkos TM, Koscianska E, Krzyzosiak WJ. Practical aspects of microRNA target prediction. Curr Mol Med 2011;11:93-109.
40. Place RF, Li LC, Pookot D, Noonan EJ, Dahiya R. MicroRNA-373 induces expression of genes with complementary promoter sequences. Proc Natl Acad Sci USA 2008;105:1608-1613.
41. Vasudevan S, Tong Y, Steitz JA. Switching from repression to activation: micrornas can up-regulate translation. Science 2007;318: 1931-1934.
42. Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, Kellis M. Systematic discovery of regulatory motifs in human promoters and 39 UTRs by comparison of several mammals. Nature 2005;434:338-345.
43. Barrett LW, Fletcher S, Wilton SD. Regulation of eukaryotic gene expression by the untranslated gene regions and other non-coding elements. Cell Mol Life Sci 2012;69:3613-3634.
44. Stark A, Brennecke J, Bushati N, Russell RB, Cohen SM. Animal MicroRNAs confer robustness to gene expression and have a significant impact on 39UTR evolution. Cell 2005;123:1133-1146.
45. Taganov KD, Boldin MP, Chang KJ, Baltimore D. NF-kappaBdependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci USA 2006;103:12481-12486.
46. O'Connell RM, Chaudhuri AA, Rao DS, Baltimore D. Inositol phosphatase SHIP1 is a primary target of miR-155. Proc Natl Acad Sci USA 2009;106:7113-7118.
47. Bazzoni F, Rossato M, Fabbri M, Gaudiosi D, Mirolo M, Mori L, Tamassia N, Mantovani A, Cassatella MA, Locati M. Induction and regulatory function of miR-9 in human monocytes and neutrophils exposed to proinflammatory signals. Proc Natl Acad Sci USA 2009; 106:5282-5287.
48. Moschos SA, Williams AE, Perry MM, Birrell MA, Belvisi MG, Lindsay MA. Expression profiling in vivo demonstrates rapid changes in lung microRNA levels following lipopolysaccharide-induced inflammation but not in the anti-inflammatory action of glucocorticoids. BMC Genomics 2007;8:240.
49. Chamorro-Jorganes A, Araldi E, Suarez Y. MicroRNAs as pharmacological targets in endothelial cell function and dysfunction. Pharmacol Res 2013;75:15-27.
50. Zhang R, Su B. Small but influential: the role of micrornas on gene regulatory network and 3'utr evolution. J Genet Genomics 2009;36:1-6.
51. Nielsen JA, Lau P, Maric D, Barker JL, Hudson LD. Integrating microRNA and mRNA expression profiles of neuronal progenitors to identify regulatory networks underlying the onset of cortical neurogenesis. BMC Neurosci 2009;10:98.
52. Bagga S, Bracht J, Hunter S, Massirer K, Holtz J, Eachus R, Pasquinelli AE. Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation. Cell 2005;122:553-563.
53. Liu Z, Wang D, Hu Y, Zhou G, Zhu C, Yu Q, Chi Y, Cao Y, Jia C, Zou Q. MicroRNA-146a negatively regulates PTGS2 expression induced by helicobacter pylori in human gastric epithelial cells. J Gastroenterol 2013;48:86-92.
54. Giraldez AJ, Mishima Y, Rihel J, Grocock RJ, Van Dongen S, Inoue K, Enright AJ, Schier AF. Zebrafish mir-430 promotes deadenylation and clearance of maternal mrnas. Science 2006;312:75-79.
55. Wu L, Fan J, Belasco JG. MicroRNAs direct rapid deadenylation of mRNA. Proc Natl Acad Sci USA 2006;103:4034-4039.