-
2
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
DOI 10.1056/NEJMoa043330
-
Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352(10):987-96. (Pubitemid 40349501)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.10
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den, B.M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.B.6
Belanger, K.7
Brandes, A.A.8
Marosi, C.9
Bogdahn, U.10
Curschmann, J.11
Janzer, R.C.12
Ludwin, S.K.13
Gorlia, T.14
Allgeier, A.15
Lacombe, D.16
Cairncross, J.G.17
Eisenhauer, E.18
Mirimanoff, R.O.19
-
3
-
-
32044464123
-
Epidermal growth factor receptor (EGFR) signaling in cancer
-
DOI 10.1016/j.gene.2005.10.018, PII S0378111905006347
-
Normanno N, De Luca A, Bianco C, et al. Epidermal growth factor receptor (EGFR) signaling in cancer. Gene. 2006;366:2-16. (Pubitemid 43199589)
-
(2006)
Gene
, vol.366
, Issue.1
, pp. 2-16
-
-
Normanno, N.1
De Luca, A.2
Bianco, C.3
Strizzi, L.4
Mancino, M.5
Maiello, M.R.6
Carotenuto, A.7
De Feo, G.8
Caponigro, F.9
Salomon, D.S.10
-
4
-
-
52649160344
-
EGFR family: Structure physiology signaling and therapeutic targets
-
Burgess AW. EGFR family: structure physiology signaling and therapeutic targets. Growth Factors. 2008;26:263-74.
-
(2008)
Growth Factors
, vol.26
, pp. 263-274
-
-
Burgess, A.W.1
-
5
-
-
0025790916
-
Genes for epidermal growth factor receptor, transforming growth factor alpha, and epidermal growth factor and their expression in human gliomas in vivo
-
Ekstrand AJ, James CD, Cavenee WK, et al. Genes for epidermal growth factor receptor, transforming growth factor alpha, and epidermal growth factor and their expression in human gliomas in vivo. Cancer Res. 1991;51:2164-72.
-
(1991)
Cancer Res
, vol.51
, pp. 2164-2172
-
-
Ekstrand, A.J.1
James, C.D.2
Cavenee, W.K.3
-
6
-
-
34250892787
-
EGFRvIII status defines distinct subtypes of glioblastoma: An analysis of 649 cases
-
abstract. Abstract PA-26
-
Pelloski CE, Zhang L, Lin E, et al. EGFRvIII status defines distinct subtypes of glioblastoma: an analysis of 649 cases [abstract]. Neuro-Oncol. 2006;8:462. Abstract PA-26.
-
(2006)
Neuro-Oncol
, vol.8
, pp. 462
-
-
Pelloski, C.E.1
Zhang, L.2
Lin, E.3
-
7
-
-
34250803209
-
Molecularly targeted therapy for malignant glioma
-
Sathornsumetree S, Reardon DA, Desjardins A, et al. Molecularly targeted therapy for malignant glioma. Cancer. 2007;110:13 - 24.
-
(2007)
Cancer
, vol.110
, pp. 13-24
-
-
Sathornsumetree, S.1
Reardon, D.A.2
Desjardins, A.3
-
8
-
-
34250189213
-
Epidermal growth factor receptor variant III status defines clinically distinct subtypes of glioblastoma
-
DOI 10.1200/JCO.2006.08.0705
-
Pelloski CE, Ballman KV, Furth AF, et al. Epidermal growth factor receptor variant III status defines clinically distinct subtypes of glioblastoma. J Clin Oncol. 2007;25:2288-94. (Pubitemid 46954657)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.16
, pp. 2288-2294
-
-
Pelloski, C.E.1
Ballman, K.V.2
Furth, A.F.3
Zhang, L.4
Lin, E.5
Sulman, E.P.6
Bhat, K.7
McDonald, J.M.8
Yung, W.K.A.9
Colman, H.10
Woo, S.Y.11
Heimberger, A.B.12
Suki, D.13
Prados, M.D.14
Chang, S.M.15
Barker II, F.G.16
Buckner, J.C.17
James, C.D.18
Aldape, K.19
-
9
-
-
0035479296
-
EGFR overexpression and radiation response in glioblastoma multiforme
-
DOI 10.1016/S0360-3016(01)01609-1, PII S0360301601016091
-
Barker 2nd FG, Simmons ML, Chang SM, et al. EGFR overexpression and radiation response in glioblastoma multiforme. Int J Radiat Oncol Biol Phys. 2001;51:410-8. (Pubitemid 32888171)
-
(2001)
International Journal of Radiation Oncology Biology Physics
, vol.51
, Issue.2
, pp. 410-418
-
-
Barker II, F.G.1
Simmons, M.L.2
Chang, S.M.3
Prados, M.D.4
Larson, D.A.5
Sneed, P.K.6
Wara, W.M.7
Berger, M.S.8
Chen, P.9
Israel, M.A.10
Aldape, K.D.11
-
10
-
-
26044467362
-
Amplification of genes encoding KIT, PDGFRalpha and VEGFR2 receptor tyrosine kinases is frequent in glioblastoma multiforme
-
DOI 10.1002/path.1823
-
Joensuu H, Puputti M, Sihto H, et al. Amplification of genes encoding KIT, PDGFRα and VEGFR2 receptor tyrosine kinases is frequent in glioblastoma multiforme. J Pathol. 2005;207:224-31. (Pubitemid 41404153)
-
(2005)
Journal of Pathology
, vol.207
, Issue.2
, pp. 224-231
-
-
Joensuu, H.1
Puputti, M.2
Sihto, H.3
Tynninen, O.4
Nupponen, N.N.5
-
11
-
-
9044248587
-
Association of loss of heterozygosity on chromosome 17p with high platelet-derived growth factor alpha receptor expression in human malignant gliomas
-
Hermanson M, Funa K, Koopmann J, et al. Association of loss of heterozygosity on chromosome 17p with high platelet-derived growth factor α receptor expression in human malignant gliomas. Cancer Res. 1996;56:164-71. (Pubitemid 26010396)
-
(1996)
Cancer Research
, vol.56
, Issue.1
, pp. 164-171
-
-
Hermanson, M.1
Funa, K.2
Koopmann, J.3
Maintz, D.4
Waha, A.5
Westermark, B.6
Heldin, C.-H.7
Wiestler, O.D.8
Louis, D.N.9
Von Deimling, A.10
Nister, M.11
-
12
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
Verhaak RG, Hoadley KA, Purdom E, et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell. 2010;17:98-110.
-
(2010)
Cancer Cell
, vol.17
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
-
13
-
-
34547757537
-
Exogenous Platelet-Derived Growth Factor (PDGF) induces human astrocytoma cell line proliferation
-
Ranza E, Facoetti A, Morbini P, et al. Exogenous platelet-derived growth factor (PDGF) induces human astrocytoma cell line proliferation. Anticancer Res. 2007;27:2161-6. (Pubitemid 47228049)
-
(2007)
Anticancer Research
, vol.27
, Issue.4 B
, pp. 2161-2166
-
-
Ranza, E.1
Facoetti, A.2
Morbini, P.3
Benericetti, E.4
Nano, R.5
-
14
-
-
0026446102
-
Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
-
Plate KH, Breier G, Weich HA, et al. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature. 1992;359:845-8.
-
(1992)
Nature
, vol.359
, pp. 845-848
-
-
Plate, K.H.1
Breier, G.2
Weich, H.A.3
-
15
-
-
14644415949
-
Biology and clinical development of vascular endothelial growth factor-targeted therapy in renal cell carcinoma
-
DOI 10.1200/JCO.2005.01.186
-
Rini BI, Small EJ. Biology and clinical development of vascular endothelial growth factor-targeted therapy in renal cell carcinoma. J Clin Oncol. 2005;23(5):1028-43. (Pubitemid 46202321)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.5
, pp. 1028-1043
-
-
Rini, B.I.1
Small, E.J.2
-
16
-
-
0033818764
-
Angiogenesis in malignant primary and metastatic brain tumors
-
Reijneveld JC, Voest EE, Taphoorn MJ. Angiogenesis in malignant primary and metastatic brain tumors. J Neurol. 2000;247:597-608.
-
(2000)
J Neurol
, vol.247
, pp. 597-608
-
-
Reijneveld, J.C.1
Voest, E.E.2
Taphoorn, M.J.3
-
17
-
-
34249113455
-
Integrin inhibitors reaching the clinic
-
DOI 10.1200/JCO.2006.09.8376
-
Stupp R, Ruegg C. Integrin inhibitors reaching the clinic. J Clin Oncol. 2007;25:1637-8. (Pubitemid 46797938)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.13
, pp. 1637-1638
-
-
Stupp, R.1
Ruegg, C.2
-
18
-
-
0026574125
-
Role of integrin alpha 4 beta 7/alpha 4 beta P inlymphocyte adherence to fibronectin and VCAM-1 and in homotypic cell clustering
-
Ruegg C, Postigo AA, Sikorski EE, et al. Role of integrin alpha 4 beta 7/alpha 4 beta P inlymphocyte adherence to fibronectin and VCAM-1 and in homotypic cell clustering. J Cell Biol. 1992;117: 179-89.
-
(1992)
J Cell Biol
, vol.117
, pp. 179-189
-
-
Ruegg, C.1
Postigo, A.A.2
Sikorski, E.E.3
-
19
-
-
35348866157
-
Integrins: Molecular determinants of glioma invasion
-
DOI 10.1016/j.jocn.2007.06.019, PII S0967586807003797
-
D'Abaco GM, Kaye AH. Integrins: molecular determinants of glioma invasion. J Clin Neurosci. 2007;14:1041-8. (Pubitemid 47588943)
-
(2007)
Journal of Clinical Neuroscience
, vol.14
, Issue.11
, pp. 1041-1048
-
-
D'Abaco, G.M.1
Kaye, A.H.2
-
20
-
-
3042823868
-
The prognostic significance of phosphatidylinositol 3-kinase pathway activation in human gliomas
-
DOI 10.1200/JCO.2004.07.193
-
Chakravarti A, Zhai G, Suzuki Y, et al. The prognostic significance of phosphatidylinositol 3-kinase pathway activation in human gliomas. J Clin Oncol. 2004;22:1926-33. (Pubitemid 41095185)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.10
, pp. 1926-1933
-
-
Chakravarti, A.1
Zhai, G.2
Suzuki, Y.3
Sarkesh, S.4
Black, P.M.5
Muzikansky, A.6
Loeffler, J.S.7
-
21
-
-
0030799909
-
Somatic mutations of PTEN in glioblastoma multiforme
-
Wang SI, Puc J, Li J, et al. Somatic mutations of PTEN in glioblastoma multiforme. Cancer Res. 1997;57:4183-6. (Pubitemid 27413419)
-
(1997)
Cancer Research
, vol.57
, Issue.19
, pp. 4183-4186
-
-
Wang, S.I.1
Puc, J.2
Li, J.3
Bruce, J.N.4
Cairns, P.5
Sidransky, D.6
Parsons, R.7
-
22
-
-
0038615946
-
Analysis of the phosphatidylinositol 3′-kinase signaling pathway in glioblastoma patients in vivo
-
Choe G, Horvath S, Cloughesy TF, et al. Analysis of the phosphatidylinositol 3′-kinase signaling pathway in glioblastoma patients in vivo. Cancer Res. 2003;63:2742-6. (Pubitemid 36667143)
-
(2003)
Cancer Research
, vol.63
, Issue.11
, pp. 2742-2746
-
-
Choe, G.1
Horvath, S.2
Cloughesy, T.F.3
Crosby, K.4
Seligson, D.5
Palotie, A.6
Inge, L.7
Smith, B.L.8
Sawyers, C.L.9
Mischel, P.S.10
-
23
-
-
0025790389
-
Enhanced protein kinase C activity correlates with the growth rate of malignant gliomas in vitro
-
Couldwell WT, Uhm JH, Antel JP, et al. Enhanced protein kinase C activity correlates with the growth rate of malignant gliomas in vitro. Neurosurgery. 1991;29:880-7.
-
(1991)
Neurosurgery
, vol.29
, pp. 880-887
-
-
Couldwell, W.T.1
Uhm, J.H.2
Antel, J.P.3
-
24
-
-
0025363850
-
Role of nuclear protein kinase C in the mitogenic response to platelet-derived growth factor
-
Fields AP, Tyler G, Kraft AS, et al. Role of nuclear protein kinase C in the mitogenic response to platelet-derived growth factor. J Cell Sci. 1990;96:107-14.
-
(1990)
J Cell Sci
, vol.96
, pp. 107-114
-
-
Fields, A.P.1
Tyler, G.2
Kraft, A.S.3
-
25
-
-
0032478610
-
Requirement of Ras-GTP-Raf complexes for activation of Raf-1 by protein kinase C
-
DOI 10.1126/science.280.5360.109
-
Marais R, Light Y, Mason C, et al. Requirement of Ras-GTP-Raf complexes for activation of Raf-1 by protein kinase C. Science. 1998;280:109-12. (Pubitemid 28169093)
-
(1998)
Science
, vol.280
, Issue.5360
, pp. 109-112
-
-
Marais, R.1
Light, Y.2
Mason, C.3
Paterson, H.4
Olson, M.F.5
Marshall, C.J.6
-
26
-
-
0028073606
-
Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation
-
Freed E, Symons M, Macdonald SG, et al. Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation. Science. 1994;265:1713-6. (Pubitemid 24314903)
-
(1994)
Science
, vol.265
, Issue.5179
, pp. 1713-1716
-
-
Freed, E.1
Symons, M.2
Macdonald, S.G.3
McCormick, F.4
Ruggieri, R.5
-
27
-
-
0026754369
-
Activation of the MAP kinase pathway by the protein kinase raf
-
Howe L, Leevers S, Gómez N, et al. Activation of the MAP kinase pathway by the protein kinase raf. Cell. 1992;71:335-42.
-
(1992)
Cell
, vol.71
, pp. 335-342
-
-
Howe, L.1
Leevers, S.2
Gómez, N.3
-
28
-
-
8844252330
-
Mutation analysis of the Ras pathway genes NRAS, HRAS, KRAS and BRAF in glioblastomas
-
DOI 10.1007/s00401-004-0929-9
-
Knobbe CB, Reifenberger J, Reifenberger G. Mutation analysis of the Ras pathway genes NRAS, HRAS, KRAS and BRAF in glioblastomas. Acta Neuropathol (Berl). 2004;108:467-70. (Pubitemid 39534587)
-
(2004)
Acta Neuropathologica
, vol.108
, Issue.6
, pp. 467-470
-
-
Knobbe, C.B.1
Reifenberger, J.2
Reifenberger, G.3
-
29
-
-
33745307617
-
Ras, PI(3)K and mTOR signalling controls tumour cell growth
-
DOI 10.1038/nature04869, PII NATURE04869
-
Shaw RJ, Cantley LC. Ras, PI(3)K and mTOR signalling controls tumour cell growth. Nature. 2006;441:424-30. (Pubitemid 44050136)
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 424-430
-
-
Shaw, R.J.1
Cantley, L.C.2
-
30
-
-
33746046387
-
Prognostic associations of activated mitogen-activated protein kinase and Akt pathways in glioblastoma
-
DOI 10.1158/1078-0432.CCR-05-2202
-
Pelloski CE, Lin E, Zhang L, et al. Prognostic associations of activated mitogen-activated protein kinase and Akt pathways in glioblastoma. Clin Cancer Res. 2006;12:3935-41. (Pubitemid 44078078)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.13
, pp. 3935-3941
-
-
Pelloski, C.E.1
Lin, E.2
Zhang, L.3
Yung, W.K.A.4
Colman, H.5
Liu, J.-L.6
Woo, S.Y.7
Heimberger, A.B.8
Suki, D.9
Prados, M.10
Chang, S.11
Barker III, F.G.12
Fuller, G.N.13
Aldape, K.D.14
-
31
-
-
70149112112
-
Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients
-
Lu KV, Zhu S, Cvrljevic A, et al. Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients. Cancer Res. 2009;69:6889-98.
-
(2009)
Cancer Res
, vol.69
, pp. 6889-6898
-
-
Lu, K.V.1
Zhu, S.2
Cvrljevic, A.3
-
32
-
-
60149089005
-
Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy
-
Du J, Bernasconi P, Clauser KR, et al. Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy. Nat Biotechnol. 2009;27:77-83.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 77-83
-
-
Du, J.1
Bernasconi, P.2
Clauser, K.R.3
-
33
-
-
58149147368
-
Single-agent and combination therapeutic strategies to inhibit hepatocyte growth factor/MET signaling in cancer
-
Toschi L, Janne PA. Single-agent and combination therapeutic strategies to inhibit hepatocyte growth factor/MET signaling in cancer. Clin Cancer Res. 2008;14:5941-6.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5941-5946
-
-
Toschi, L.1
Janne, P.A.2
-
34
-
-
58949099258
-
Prognostic significance of c-Met expression in glioblastomas
-
Kong DS, Song SY, Kim DH, et al. Prognostic significance of c-Met expression in glioblastomas. Cancer. 2009;115:140-8.
-
(2009)
Cancer
, vol.115
, pp. 140-148
-
-
Kong, D.S.1
Song, S.Y.2
Kim, D.H.3
-
35
-
-
0035862199
-
The human histone deacetylase family
-
DOI 10.1006/excr.2000.5080
-
Gray S, Ekström T. The human histone deacetylase family. Exp Cell Res. 2001;262:75-83. (Pubitemid 32980246)
-
(2001)
Experimental Cell Research
, vol.262
, Issue.2
, pp. 75-83
-
-
Gray, S.G.1
Ekstrom, T.J.2
-
36
-
-
0034596309
-
Histone deacetylase inhibitors: Inducers of differentiation or apoptosis of transformed cells
-
Marks PA, Richon VM, Rifkind RA. Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells. J Natl Cancer Inst. 2000;92:1210-6. (Pubitemid 30627729)
-
(2000)
Journal of the National Cancer Institute
, vol.92
, Issue.15
, pp. 1210-1216
-
-
Marks, P.A.1
Richon, V.M.2
Rifkind, R.A.3
-
37
-
-
0029294663
-
Trichostatin A and trapoxin: Novel chemical probes for the role of histone acetylation in chromatin structure and function
-
Yoshida M, Horinouchi S, Beppu T. Trichostatin A and trapoxin: novel chemical probes for the role of histone acetylation in chromatin structure and function. Bioessays. 1995;17:423-30.
-
(1995)
Bioessays
, vol.17
, pp. 423-430
-
-
Yoshida, M.1
Horinouchi, S.2
Beppu, T.3
-
38
-
-
31544481156
-
Targeted molecular therapy of malignant gliomas
-
Kesari S, Ramakrishna N, Sauvageot C, et al. Targeted molecular therapy of malignant gliomas. Curr Oncol Rep. 2006;8:58-70. (Pubitemid 43154265)
-
(2006)
Current Oncology Reports
, vol.8
, Issue.1
, pp. 58-70
-
-
Kesari, S.1
Ramakrishna, N.2
Sauvageot, C.3
Stiles, C.D.4
Wen, P.Y.5
-
39
-
-
2342613652
-
The proteasome: A suitable antineoplastic target
-
Adams J. The proteasome: a suitable antineoplastic target. Nat Rev Cancer. 2004;4:349-60. (Pubitemid 38579481)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.5
, pp. 349-360
-
-
Adams, J.1
-
40
-
-
0036341291
-
Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo
-
Fulda S, Wick W, Weller M, et al. Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo. Nat Med. 2002;8:808-15.
-
(2002)
Nat Med
, vol.8
, pp. 808-815
-
-
Fulda, S.1
Wick, W.2
Weller, M.3
-
41
-
-
40149099894
-
Yes and PI3K Bind CD95 to Signal Invasion of Glioblastoma
-
DOI 10.1016/j.ccr.2008.02.003, PII S1535610808000433
-
Kleber S, Sancho-Martinez I, Wiestler B, et al. Yes and PI3K bind CD95 to signal invasion of glioblastoma. Cancer Cell. 2008;13: 235-48. (Pubitemid 351324880)
-
(2008)
Cancer Cell
, vol.13
, Issue.3
, pp. 235-248
-
-
Kleber, S.1
Sancho-Martinez, I.2
Wiestler, B.3
Beisel, A.4
Gieffers, C.5
Hill, O.6
Thiemann, M.7
Mueller, W.8
Sykora, J.9
Kuhn, A.10
Schreglmann, N.11
Letellier, E.12
Zuliani, C.13
Klussmann, S.14
Teodorczyk, M.15
Grone, H.-J.16
Ganten, T.M.17
Sultmann, H.18
Tuttenberg, J.19
Von, D.A.20
Regnier-Vigouroux, A.21
Herold-Mende, C.22
Martin-Villalba, A.23
more..
-
43
-
-
23144438578
-
Chaperone proteins and brain tumors: Potential targets and possible therapeutics
-
Graner MW, Bigner DD. Chaperone proteins and brain tumors: potential targets and possible therapeutics. Neuro Oncol. 2005;7: 260-78.
-
(2005)
Neuro Oncol
, vol.7
, pp. 260-278
-
-
Graner, M.W.1
Bigner, D.D.2
-
44
-
-
33646735616
-
Cooperative inhibitory effect of ZD1839 (Iressa) in combination with 17-AAG on glioma cell growth
-
Premkumar D, Arnold B, Pollack I. Cooperative inhibitory effect of ZD1839 (Iressa) in combination with 17-AAG on glioma cell growth. Mol Carcinog. 2006;45:288-301.
-
(2006)
Mol Carcinog
, vol.45
, pp. 288-301
-
-
Premkumar, D.1
Arnold, B.2
Pollack, I.3
-
45
-
-
77957944911
-
Pre-clinical and clinical evaluation of PARP inhibitors as tumour-specific radiosensitizers
-
Powell C, Mikropoulos C, Kaye SB, et al. Pre-clinical and clinical evaluation of PARP inhibitors as tumour-specific radiosensitizers. Cancer Treat Rev. 2010;36:566-75.
-
(2010)
Cancer Treat Rev
, vol.36
, pp. 566-575
-
-
Powell, C.1
Mikropoulos, C.2
Kaye, S.B.3
-
46
-
-
84864859391
-
PARP-1 protein expression in glioblastoma multiforme
-
Galia A, Calogero AE, Condorelli R, et al. PARP-1 protein expression in glioblastoma multiforme. Eur J Histochem. 2012;56(1):e9.
-
(2012)
Eur J Histochem
, vol.56
, Issue.1
-
-
Galia, A.1
Calogero, A.E.2
Condorelli, R.3
-
47
-
-
84880045561
-
RTOG 0913: A phase 1 study of daily everolimus (RAD001) in combination with radiation therapy and temozolomide in patients with newly diagnosed glioblastoma
-
Chinnaiyan P, Won M, Wen PY, et al. RTOG 0913: a phase 1 study of daily everolimus (RAD001) in combination with radiation therapy and temozolomide in patients with newly diagnosed glioblastoma. Int J Radiat Oncol Biol Phys. 2013;86(5):880-4.
-
(2013)
Int J Radiat Oncol Biol Phys
, vol.86
, Issue.5
, pp. 880-884
-
-
Chinnaiyan, P.1
Won, M.2
Wen, P.Y.3
-
48
-
-
84875239034
-
RTOG 0211: A phase 1/2 study of radiation therapy with concurrent gefitinib for newly diagnosed glioblastoma patients
-
Chakravarti A, Wang M, Robins HI, et al. RTOG 0211: a phase 1/2 study of radiation therapy with concurrent gefitinib for newly diagnosed glioblastoma patients. Int J Radiat Oncol Biol Phys. 2013;85(5):1206-11.
-
(2013)
Int J Radiat Oncol Biol Phys
, vol.85
, Issue.5
, pp. 1206-1211
-
-
Chakravarti, A.1
Wang, M.2
Robins, H.I.3
-
49
-
-
84869189499
-
EORTC 26083 phase I/II trial of dasatinib in combination with CCNU in patients with recurrent glioblastoma
-
Franceschi E, Stupp R, van den Bent MJ, et al. EORTC 26083 phase I/II trial of dasatinib in combination with CCNU in patients with recurrent glioblastoma. Neuro Oncol. 2012;12(12):1503-10.
-
(2012)
Neuro Oncol
, vol.12
, Issue.12
, pp. 1503-1510
-
-
Franceschi, E.1
Stupp, R.2
Van Den Bent, M.J.3
-
50
-
-
84864400820
-
Phase I/II study of oral erlotinib for treatment of relapsed/refractory glioblastoma multiforme and anaplastic astrocytoma
-
Kesavabhotla K, Schlaff CD, Shin B, et al. Phase I/II study of oral erlotinib for treatment of relapsed/refractory glioblastoma multiforme and anaplastic astrocytoma. J Exp Ther Oncol. 2012;10(1):71-81.
-
(2012)
J Exp Ther Oncol
, vol.10
, Issue.1
, pp. 71-81
-
-
Kesavabhotla, K.1
Schlaff, C.D.2
Shin, B.3
-
51
-
-
84868561843
-
Phase I study of vorinostat in combination with temozolomide in patients with high-grade gliomas: North American Brain Tumor Consortium Study 04-03
-
Lee EQ, Puduvalli VK, Reid JM, et al. Phase I study of vorinostat in combination with temozolomide in patients with high-grade gliomas: North American Brain Tumor Consortium Study 04-03. Clin Cancer Res. 2012;18(21):6032-9.
-
(2012)
Clin Cancer Res
, vol.18
, Issue.21
, pp. 6032-6039
-
-
Lee, E.Q.1
Puduvalli, V.K.2
Reid, J.M.3
-
52
-
-
84863879018
-
A phase II trial with bevacizumab and irinotecan for patients with primary brain tumors and progression after standard therapy
-
Moller S, Grunnet K, Hansen S, et al. A phase II trial with bevacizumab and irinotecan for patients with primary brain tumors and progression after standard therapy. Acta Oncol. 2012;51(6): 797-804.
-
(2012)
Acta Oncol
, vol.51
, Issue.6
, pp. 797-804
-
-
Moller, S.1
Grunnet, K.2
Hansen, S.3
-
53
-
-
84859544365
-
A phase I study of LY317615 (enzastaurin) and temozolomide in patients with gliomas (EORTC trial 26054)
-
Rampling R, Sanson M, Gorlia T, et al. A phase I study of LY317615 (enzastaurin) and temozolomide in patients with gliomas (EORTC trial 26054). Neuro Oncol. 2012;14(3):344-50.
-
(2012)
Neuro Oncol
, vol.14
, Issue.3
, pp. 344-350
-
-
Rampling, R.1
Sanson, M.2
Gorlia, T.3
-
54
-
-
84875530192
-
A phase I study of temozolomide and everolimus (RAD001) in patients with newly diagnosed and progressive glioblastoma either receiving or not receiving enzyme-inducing anticonvulsants: An NCIC CTG study
-
Mason WP, Macneil M, Kavan P, et al. A phase I study of temozolomide and everolimus (RAD001) in patients with newly diagnosed and progressive glioblastoma either receiving or not receiving enzyme-inducing anticonvulsants: an NCIC CTG study. Invest New Drugs. 2012;30(6):2344-51.
-
(2012)
Invest New Drugs
, vol.30
, Issue.6
, pp. 2344-2351
-
-
Mason, W.P.1
Macneil, M.2
Kavan, P.3
-
55
-
-
84863595655
-
A phase II study of the Ras-MAPK signaling pathway inhibitor TLN-4601 in patients with glioblastoma at first progression
-
Mason WP, Belanger K, Nicholas G, et al. A phase II study of the Ras-MAPK signaling pathway inhibitor TLN-4601 in patients with glioblastoma at first progression. J Neurooncol. 2012;107(2):343-9.
-
(2012)
J Neurooncol
, vol.107
, Issue.2
, pp. 343-349
-
-
Mason, W.P.1
Belanger, K.2
Nicholas, G.3
-
56
-
-
84861312289
-
Phase II study of carboplatin, irinotecan, and bevacizumab for bevacizumab naïve, recurrent glioblastoma
-
Reardon DA, Desjardins A, Peters KB, et al. Phase II study of carboplatin, irinotecan, and bevacizumab for bevacizumab naïve, recurrent glioblastoma. J Neurooncol. 2012;107(1):155-64.
-
(2012)
J Neurooncol
, vol.107
, Issue.1
, pp. 155-164
-
-
Reardon, D.A.1
Desjardins, A.2
Peters, K.B.3
-
57
-
-
84863011588
-
Phase II and pharmacogenomics study of enzastaurin plus temozolomide during and following radiation therapy in patients with newly diagnosed glioblastoma multiforme and gliosarcoma
-
Butowski N, Chang SM, Lamborn KR, et al. Phase II and pharmacogenomics study of enzastaurin plus temozolomide during and following radiation therapy in patients with newly diagnosed glioblastoma multiforme and gliosarcoma. Neuro Oncol. 2011;13(12):1331-8.
-
(2011)
Neuro Oncol
, vol.13
, Issue.12
, pp. 1331-1338
-
-
Butowski, N.1
Chang, S.M.2
Lamborn, K.R.3
-
58
-
-
83055173043
-
Cilengitide in patients with recurrent glioblastoma: The results of NABTC 03-02, a phase II trial with measures of treatment delivery
-
Gilbert MR, Kuhn J, Lamborn KR, et al. Cilengitide in patients with recurrent glioblastoma: the results of NABTC 03-02, a phase II trial with measures of treatment delivery. J Neurooncol. 2012;106(1): 147-53.
-
(2012)
J Neurooncol
, vol.106
, Issue.1
, pp. 147-153
-
-
Gilbert, M.R.1
Kuhn, J.2
Lamborn, K.R.3
-
59
-
-
80855145598
-
Phase 2 study of carboplatin, irinotecan and bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy
-
Reardon DA, Desjardins A, Peters KB, et al. Phase 2 study of carboplatin, irinotecan and bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy. Cancer. 2011;117(23): 5351-8.
-
(2011)
Cancer
, vol.117
, Issue.23
, pp. 5351-5358
-
-
Reardon, D.A.1
Desjardins, A.2
Peters, K.B.3
-
60
-
-
79959213028
-
The addition of bevacizumab to standard radiation therapy and temozolomide followed by bevacizumab, temozolomide and irinotecan for newly diagnosed glioblastoma
-
Vredenburgh JJ, Desjardins A, Reardon DA, et al. The addition of bevacizumab to standard radiation therapy and temozolomide followed by bevacizumab, temozolomide and irinotecan for newly diagnosed glioblastoma. Clin Cancer Res. 2011;17(12):4119-24.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.12
, pp. 4119-4124
-
-
Vredenburgh, J.J.1
Desjardins, A.2
Reardon, D.A.3
-
61
-
-
79959956310
-
A phase I/II trial of the histone deacetylase inhibitor romidepsin for adults with recurrent malignant glioma: North American Brain Tumor Consortium Study 03-03
-
Iwamoto FM, Lamborn KR, Kuhn JG, et al. A phase I/II trial of the histone deacetylase inhibitor romidepsin for adults with recurrent malignant glioma: North American Brain Tumor Consortium Study 03-03. Neuro Oncol. 2011;13(5):509-16.
-
(2011)
Neuro Oncol
, vol.13
, Issue.5
, pp. 509-516
-
-
Iwamoto, F.M.1
Lamborn, K.R.2
Kuhn, J.G.3
-
62
-
-
79955766450
-
A phase II study evaluating the efficacy and safety of AMG 102 (rilotumumab) in patients with recurrent glioblastoma
-
Wen PY, Schiff D, Cloughesy TF, et al. A phase II study evaluating the efficacy and safety of AMG 102 (rilotumumab) in patients with recurrent glioblastoma. Neuro Oncol. 2011;13(4):437-46.
-
(2011)
Neuro Oncol
, vol.13
, Issue.4
, pp. 437-446
-
-
Wen, P.Y.1
Schiff, D.2
Cloughesy, T.F.3
-
63
-
-
79951602633
-
Targeted therapy for high-grade glioma with the TGF-β2 inhibitor trabedersen: Results of a randomized and controlled phase IIb study
-
Bogdahn U, Hau P, Stockhammer G, et al. Targeted therapy for high-grade glioma with the TGF-β2 inhibitor trabedersen: results of a randomized and controlled phase IIb study. Neuro Oncol. 2011;13(1):132-42.
-
(2011)
Neuro Oncol
, vol.13
, Issue.1
, pp. 132-142
-
-
Bogdahn, U.1
Hau, P.2
Stockhammer, G.3
-
64
-
-
81855206303
-
A phase I trial of tipifarnib with radiation therapy, with and without temozolomide, for patients with newly diagnosed glioblastoma
-
Nghiemphu PL, Wen PY, Lamborn KR, et al. A phase I trial of tipifarnib with radiation therapy, with and without temozolomide, for patients with newly diagnosed glioblastoma. Int J Radiat Oncol Phys. 2011;81(5):1422-7.
-
(2011)
Int J Radiat Oncol Phys
, vol.81
, Issue.5
, pp. 1422-1427
-
-
Nghiemphu, P.L.1
Wen, P.Y.2
Lamborn, K.R.3
-
65
-
-
78349245231
-
Combination of temsirolimus (CCI-779) with chemoradiation in newly diagnosed glioblastoma multiforme (GBM) (NCCTG trial N027D) is associated with increased infectious risks
-
Sarkaria JN, Galanis E, Wu W, et al. Combination of temsirolimus (CCI-779) with chemoradiation in newly diagnosed glioblastoma multiforme (GBM) (NCCTG trial N027D) is associated with increased infectious risks. Clin Cancer Res. 2010;16(22):5573-80.
-
(2010)
Clin Cancer Res
, vol.16
, Issue.22
, pp. 5573-5580
-
-
Sarkaria, J.N.1
Galanis, E.2
Wu, W.3
-
66
-
-
80052820448
-
North Central Cancer Treatment Group Phase I trial N057K of everolimus (RAD001) and temozolomide in combination with radiation therapy in patients with newly diagnosed glioblastoma multiforme
-
Sarkaria JN, Galanis E, Wu W, et al. North Central Cancer Treatment Group Phase I trial N057K of everolimus (RAD001) and temozolomide in combination with radiation therapy in patients with newly diagnosed glioblastoma multiforme. Int J Radiat Oncol Biol Phys. 2011;81(2):468-75.
-
(2011)
Int J Radiat Oncol Biol Phys
, vol.81
, Issue.2
, pp. 468-475
-
-
Sarkaria, J.N.1
Galanis, E.2
Wu, W.3
-
67
-
-
78049306732
-
Safety and efficacy of erlotinib in first-relapse glioblastoma: A phase II open-label study
-
Yung WK, Vredenburgh JJ, Cloughesy TF, et al. Safety and efficacy of erlotinib in first-relapse glioblastoma: a phase II open-label study. Neuro Oncol. 2010;12(10):1061-70.
-
(2010)
Neuro Oncol
, vol.12
, Issue.10
, pp. 1061-1070
-
-
Yung, W.K.1
Vredenburgh, J.J.2
Cloughesy, T.F.3
-
68
-
-
79955582712
-
Phase II evaluation of gefitinib in patients with newly diagnosed grade 4 astrocytoma: Mayo/North Central Cancer Treatment Group Study N0074
-
Uhm JH, Ballman KV, Wu W, et al. Phase II evaluation of gefitinib in patients with newly diagnosed grade 4 astrocytoma: Mayo/North Central Cancer Treatment Group Study N0074. Int J Radiat Oncol Biol Phys. 2011;80(2):347-53.
-
(2011)
Int J Radiat Oncol Biol Phys
, vol.80
, Issue.2
, pp. 347-353
-
-
Uhm, J.H.1
Ballman, K.V.2
Wu, W.3
-
69
-
-
77954720781
-
Phase II study of Cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma
-
Batchelor TT, Duda DG, di Tomaso E, et al. Phase II study of Cediranib, an oral pan-vascular endothelial growth factor receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma. J Clin Oncol. 2010;28(17):2817-23.
-
(2010)
J Clin Oncol
, vol.28
, Issue.17
, pp. 2817-2823
-
-
Batchelor, T.T.1
Duda, D.G.2
Di Tomaso, E.3
-
70
-
-
77954924659
-
Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma
-
Stupp R, Hegi ME, Neyns B, et al. Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma. J Clin Oncol. 2010;28(16): 2712-8.
-
(2010)
J Clin Oncol
, vol.28
, Issue.16
, pp. 2712-2718
-
-
Stupp, R.1
Hegi, M.E.2
Neyns, B.3
-
71
-
-
77955633497
-
A Phase II study of anti-epidermal growth factor receptor radioimmunotherapy in the treatment of glioblastoma multiforme
-
Li L, Quang TS, Gracely EJ, et al. A Phase II study of anti-epidermal growth factor receptor radioimmunotherapy in the treatment of glioblastoma multiforme. J Neurosurg. 2010;113(2):192-8.
-
(2010)
J Neurosurg
, vol.113
, Issue.2
, pp. 192-198
-
-
Li, L.1
Quang, T.S.2
Gracely, E.J.3
-
72
-
-
79952194923
-
Phase 1 clinical trial of bortezomib in adults with recurrent malignant glioma
-
Phuphanich S, Supko JG, Carson KA, et al. Phase 1 clinical trial of bortezomib in adults with recurrent malignant glioma. J Neurooncol. 2010;100(1):95-103.
-
(2010)
J Neurooncol
, vol.100
, Issue.1
, pp. 95-103
-
-
Phuphanich, S.1
Supko, J.G.2
Carson, K.A.3
-
73
-
-
77957069911
-
Enzastaurin plus temozolomide with radiation therapy in glioblastoma multiforme: A phase I study
-
Butowski N, Chang SM, Lamborn KR, et al. Enzastaurin plus temozolomide with radiation therapy in glioblastoma multiforme: a phase I study. Neuro Oncol. 2010;12(6):608-13.
-
(2010)
Neuro Oncol
, vol.12
, Issue.6
, pp. 608-613
-
-
Butowski, N.1
Chang, S.M.2
Lamborn, K.R.3
-
74
-
-
75849133697
-
A phase I/II trial of enzastaurin in patients with recurrent high-grade gliomas
-
Kreisl TN, Kotliarova S, Butman JA, et al. A phase I/II trial of enzastaurin in patients with recurrent high-grade gliomas. Neuro Oncol. 2010;12(2):181-9.
-
(2010)
Neuro Oncol
, vol.12
, Issue.2
, pp. 181-189
-
-
Kreisl, T.N.1
Kotliarova, S.2
Butman, J.A.3
-
75
-
-
75749122223
-
A phase II trial of erlotinib in patients with recurrent malignant gliomas and nonprogressive glioblastoma multiforme postradiation therapy
-
Raizer JJ, Abrey LE, Lassman AB, et al. A phase II trial of erlotinib in patients with recurrent malignant gliomas and nonprogressive glioblastoma multiforme postradiation therapy. Neuro Oncol. 2010;12(1):95-103.
-
(2010)
Neuro Oncol
, vol.12
, Issue.1
, pp. 95-103
-
-
Raizer, J.J.1
Abrey, L.E.2
Lassman, A.B.3
-
76
-
-
75749110539
-
A phase I trial of erlotinib in patients with nonprogressive glioblastoma multiforme postradiation therapy, and recurrent malignant gliomas and meningiomas
-
Raizer JJ, Abrey LE, Lassman AB, et al. A phase I trial of erlotinib in patients with nonprogressive glioblastoma multiforme postradiation therapy, and recurrent malignant gliomas and meningiomas. Neuro Oncol. 2010;12(1):87-94.
-
(2010)
Neuro Oncol
, vol.12
, Issue.1
, pp. 87-94
-
-
Raizer, J.J.1
Abrey, L.E.2
Lassman, A.B.3
-
77
-
-
79959812904
-
Phase II study of metronomic chemotherapy with bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy
-
Reardon DA, Desjardins A, Peters K, et al. Phase II study of metronomic chemotherapy with bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy. J Neurooncol. 2011;103(2):371-9.
-
(2011)
J Neurooncol
, vol.103
, Issue.2
, pp. 371-379
-
-
Reardon, D.A.1
Desjardins, A.2
Peters, K.3
-
78
-
-
79951984402
-
Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme
-
Lai A, Tran A, Nghiemphu PL, et al. Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme. J Clin Oncol. 2011;29(2):142-8.
-
(2011)
J Clin Oncol
, vol.29
, Issue.2
, pp. 142-148
-
-
Lai, A.1
Tran, A.2
Nghiemphu, P.L.3
-
79
-
-
78149254368
-
Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma
-
Sampson JH, Heimberger AB, Archer GE, et al. Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma. J Clin Oncol. 2010;28(31): 4722-9.
-
(2010)
J Clin Oncol
, vol.28
, Issue.31
, pp. 4722-4729
-
-
Sampson, J.H.1
Heimberger, A.B.2
Archer, G.E.3
-
80
-
-
84856806386
-
A clinical trial of bevacizumab, temozolomide, and radiation for newly diagnosed glioblastoma
-
Narayana A, Gruber D, Kunnakkat S, et al. A clinical trial of bevacizumab, temozolomide, and radiation for newly diagnosed glioblastoma. J Neurosurg. 2012;116(2):341-5.
-
(2012)
J Neurosurg
, vol.116
, Issue.2
, pp. 341-345
-
-
Narayana, A.1
Gruber, D.2
Kunnakkat, S.3
-
81
-
-
84857373272
-
Bevacizumab and daily temozolomide for recurrent glioblastoma
-
Desjardins A, Reardon DA, Coan A, et al. Bevacizumab and daily temozolomide for recurrent glioblastoma. Cancer. 2012;118(5): 1302-12.
-
(2012)
Cancer
, vol.118
, Issue.5
, pp. 1302-1312
-
-
Desjardins, A.1
Reardon, D.A.2
Coan, A.3
-
82
-
-
84868193304
-
A safety run-in and randomized phase 2 study of cilengitide combined with chemoradiation for newly diagnosed glioblastoma (NABTT 0306)
-
Nabors LB, Mikkelsen T, Hegi ME, et al. A safety run-in and randomized phase 2 study of cilengitide combined with chemoradiation for newly diagnosed glioblastoma (NABTT 0306). Cancer. 2012;118(22):5601-7.
-
(2012)
Cancer
, vol.118
, Issue.22
, pp. 5601-5607
-
-
Nabors, L.B.1
Mikkelsen, T.2
Hegi, M.E.3
-
83
-
-
84866759977
-
Phase II study of single-agent bevacizumab in Japanese patients with recurrent malignant glioma
-
Nagane M, Nishikawa R, Narita Y, et al. Phase II study of single-agent bevacizumab in Japanese patients with recurrent malignant glioma. Jpn J Clin Oncol. 2012;42(10):887-95.
-
(2012)
Jpn J Clin Oncol
, vol.42
, Issue.10
, pp. 887-895
-
-
Nagane, M.1
Nishikawa, R.2
Narita, Y.3
-
84
-
-
77949891455
-
Phase III study of enzastaurin compared with lomustine in the treatment of recurrent intracranial glioblastoma
-
Wick W, Puduvalli VK, Chamberlain MC, et al. Phase III study of enzastaurin compared with lomustine in the treatment of recurrent intracranial glioblastoma. J Clin Oncol. 2010;28(7):1168-74.
-
(2010)
J Clin Oncol
, vol.28
, Issue.7
, pp. 1168-1174
-
-
Wick, W.1
Puduvalli, V.K.2
Chamberlain, M.C.3
-
85
-
-
77953617053
-
Phase II trial of erlotinib with temozolomide and radiation in patients with newly diagnosed glioblastoma multiforme
-
Peereboom DM, Shepard DR, Ahluwalia MS, et al. Phase II trial of erlotinib with temozolomide and radiation in patients with newly diagnosed glioblastoma multiforme. J Neurooncol. 2010;98(1):93-9.
-
(2010)
J Neurooncol
, vol.98
, Issue.1
, pp. 93-99
-
-
Peereboom, D.M.1
Shepard, D.R.2
Ahluwalia, M.S.3
-
86
-
-
71649094684
-
Metronomic chemotherapy with daily, oral etoposide plus bevacizumab for recurrent malignant glioma: A phase II study
-
Reardon DA, Desjardins A, Vredenburgh JJ, et al. Metronomic chemotherapy with daily, oral etoposide plus bevacizumab for recurrent malignant glioma: a phase II study. Br J Cancer. 2009;101(12):1986-94.
-
(2009)
Br J Cancer
, vol.101
, Issue.12
, pp. 1986-1994
-
-
Reardon, D.A.1
Desjardins, A.2
Vredenburgh, J.J.3
-
87
-
-
70350236627
-
An epidermal growth factor receptor variant III-targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme
-
Sampson JH, Archer GE, Mitchell DA, et al. An epidermal growth factor receptor variant III-targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme. Mol Cancer Ther. 2009;8(10):2773-9.
-
(2009)
Mol Cancer Ther
, vol.8
, Issue.10
, pp. 2773-2779
-
-
Sampson, J.H.1
Archer, G.E.2
Mitchell, D.A.3
-
88
-
-
70350461699
-
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
-
Friedman HS, Prados MD, Wen PY, et al. Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma. J Clin Oncol. 2009;27(28):4733-40.
-
(2009)
J Clin Oncol
, vol.27
, Issue.28
, pp. 4733-4740
-
-
Friedman, H.S.1
Prados, M.D.2
Wen, P.Y.3
-
89
-
-
70249128040
-
Talampanel with standard radiation and temozolomide in patients with newly diagnosed glioblastoma: A multicenter phase II trial
-
Grossman SA, Ye X, Chamberlain M, et al. Talampanel with standard radiation and temozolomide in patients with newly diagnosed glioblastoma: a multicenter phase II trial. J Clin Oncol. 2009;27(25):4155-61.
-
(2009)
J Clin Oncol
, vol.27
, Issue.25
, pp. 4155-4161
-
-
Grossman, S.A.1
Ye, X.2
Chamberlain, M.3
-
90
-
-
71349088046
-
A phase I/II trial of GW572016 (lapatinib) in recurrent glioblastoam multiforme: Clinical outcomes, pharmacokinetics and molecular correlation
-
Thiessen B, Stewart C, Tsao M, et al. A phase I/II trial of GW572016 (lapatinib) in recurrent glioblastoam multiforme: clinical outcomes, pharmacokinetics and molecular correlation. Cancer Chemother Pharmacol. 2010;65(2):353-61.
-
(2010)
Cancer Chemother Pharmacol
, vol.65
, Issue.2
, pp. 353-361
-
-
Thiessen, B.1
Stewart, C.2
Tsao, M.3
-
91
-
-
65349141942
-
Phase II trial of vorinostat in recurrent glioblastoma multiforme: A north central cancer treatment group study
-
Galanis E, Jaeckle KA, Maurer MJ, et al. Phase II trial of vorinostat in recurrent glioblastoma multiforme: a north central cancer treatment group study. J Clin Oncol. 2009;27(12):2052-8.
-
(2009)
J Clin Oncol
, vol.27
, Issue.12
, pp. 2052-2058
-
-
Galanis, E.1
Jaeckle, K.A.2
Maurer, M.J.3
-
92
-
-
59949083263
-
Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma
-
Kreisl TN, Kim L, Moore K, et al. Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma. J Clin Oncol. 2009;27(5): 740-5.
-
(2009)
J Clin Oncol
, vol.27
, Issue.5
, pp. 740-745
-
-
Kreisl, T.N.1
Kim, L.2
Moore, K.3
-
93
-
-
67349138194
-
Phase I trial using proteasome inhibitor botezomib and concurrent temozolomide and radiotherapy for central nervous system malignancies
-
Kubicek GJ, Werner-Wasik M, Machtay M, et al. Phase I trial using proteasome inhibitor botezomib and concurrent temozolomide and radiotherapy for central nervous system malignancies. Int J Radiat Oncol Biol Phys. 2009;74(2):433-9.
-
(2009)
Int J Radiat Oncol Biol Phys
, vol.74
, Issue.2
, pp. 433-439
-
-
Kubicek, G.J.1
Werner-Wasik, M.2
Machtay, M.3
-
94
-
-
59149086517
-
Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme and gliosarcoma
-
Prados MD, Chang SM, Butowski N, et al. Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme and gliosarcoma. J Clin Oncol. 2009;27(4):579-84.
-
(2009)
J Clin Oncol
, vol.27
, Issue.4
, pp. 579-584
-
-
Prados, M.D.1
Chang, S.M.2
Butowski, N.3
-
95
-
-
57149108506
-
Randomized phase II study of cilengitide, an integrin-targeting arginine-glycine-aspartic acid peptide, in recurrent glioblastoma multiforme
-
Reardon DA, Fink KL, Mikkelsen T, et al. Randomized phase II study of cilengitide, an integrin-targeting arginine-glycine-aspartic acid peptide, in recurrent glioblastoma multiforme. J Clin Oncol. 2008;26(34):5610-7.
-
(2008)
J Clin Oncol
, vol.26
, Issue.34
, pp. 5610-5617
-
-
Reardon, D.A.1
Fink, K.L.2
Mikkelsen, T.3
-
96
-
-
57149118473
-
Phase I/II trial of erlotinib and temozolomide with radiation therapy in the treatment of newly diagnosed glioblastoma multiforme: North Central Cancer Treatment Group Study N0177
-
Brown PD, Krishnan S, Sarkaria JN, et al. Phase I/II trial of erlotinib and temozolomide with radiation therapy in the treatment of newly diagnosed glioblastoma multiforme: North Central Cancer Treatment Group Study N0177. J Clin Oncol. 2008;26(34):5603-9.
-
(2008)
J Clin Oncol
, vol.26
, Issue.34
, pp. 5603-5609
-
-
Brown, P.D.1
Krishnan, S.2
Sarkaria, J.N.3
-
97
-
-
50649118313
-
Ras pathway activation in gliomas: A strategic target for intranasal administration of perillyl alcohol
-
Warsz
-
da Fonseca CO, Linden R, Futuro D, et al. Ras pathway activation in gliomas: a strategic target for intranasal administration of perillyl alcohol. Arch Immunol Ther Exp (Warsz). 2008;56(4):267-76.
-
(2008)
Arch Immunol Ther Exp
, vol.56
, Issue.4
, pp. 267-276
-
-
Da Fonseca, C.O.1
Linden, R.2
Futuro, D.3
-
98
-
-
60549100910
-
Phase II preradiation R115777 (tipifarnib) in newly diagnosed GBM with residual enhancing disease
-
Lustig R, Mikkelsen T, Lesser G, et al. Phase II preradiation R115777 (tipifarnib) in newly diagnosed GBM with residual enhancing disease. Neuro Oncol. 2008;10(6):1004-9.
-
(2008)
Neuro Oncol
, vol.10
, Issue.6
, pp. 1004-1009
-
-
Lustig, R.1
Mikkelsen, T.2
Lesser, G.3
-
99
-
-
50649103493
-
Phase II study of carboplatin and erlotinib (Tarceva, OSI-774) in patients with recurrent glioblastoma
-
De Groot JF, Gilbert MR, Aldape K, et al. Phase II study of carboplatin and erlotinib (Tarceva, OSI-774) in patients with recurrent glioblastoma. J Neurooncol. 2008;90(1):89-97.
-
(2008)
J Neurooncol
, vol.90
, Issue.1
, pp. 89-97
-
-
De Groot, J.F.1
Gilbert, M.R.2
Aldape, K.3
-
100
-
-
54049094871
-
Phase I safety study of escalating doses of atrasentan in adults with recurrent malignant glioma
-
Phuphanich S, Carson KA, Grossman SA, et al. Phase I safety study of escalating doses of atrasentan in adults with recurrent malignant glioma. Neuro Oncol. 2008;10(4):617-23.
-
(2008)
Neuro Oncol
, vol.10
, Issue.4
, pp. 617-623
-
-
Phuphanich, S.1
Carson, K.A.2
Grossman, S.A.3
-
101
-
-
45249097586
-
Phase II pilot study of bevacizumab in combination with temozolomide and regional radiation therapy for up-front treatment of patients with newly diagnosed glioblastoma multiforme: Interim analysis of safety and tolerability
-
Lai A, Filka E, McGibbon B, et al. Phase II pilot study of bevacizumab in combination with temozolomide and regional radiation therapy for up-front treatment of patients with newly diagnosed glioblastoma multiforme: interim analysis of safety and tolerability. Int J Radiat Oncol Biol Phys. 2008;71(5):1372-80.
-
(2008)
Int J Radiat Oncol Biol Phys
, vol.71
, Issue.5
, pp. 1372-1380
-
-
Lai, A.1
Filka, E.2
McGibbon, B.3
-
102
-
-
38849208347
-
Antitumor activity of rapamycin in a phase I trial for patients with recurrent PTEN-deficient glioblastoma
-
Cloughesy TF, Yoshimoto K, Nghiemphu P, et al. Antitumor activity of rapamycin in a phase I trial for patients with recurrent PTEN-deficient glioblastoma. PLoS Med. 2008;5(1):e8.
-
(2008)
PLoS Med
, vol.5
, Issue.1
-
-
Cloughesy, T.F.1
Yoshimoto, K.2
Nghiemphu, P.3
-
103
-
-
45349101800
-
188Re in adult recurrent high-grade glioma
-
Casaco A, Lopez G, Garcia I, et al. Phase I single-dose study of intracavitary-administered Nimotuzumab labeled with 188 Re in adult recurrent high-grade glioma. Cancer Biol Ther. 2008;7(3):333-9. (Pubitemid 351847044)
-
(2008)
Cancer Biology and Therapy
, vol.7
, Issue.3
, pp. 333-339
-
-
Casaco, P.A.1
Lopez, G.2
Garcia, I.3
Rodriguez, J.A.4
Fernandez, R.5
Figueredo, J.6
Torres, L.7
Perera, A.8
Batista, J.9
Leyva, R.10
Pena, Y.11
Amador, Z.12
Gonzalez, A.13
Estupinan, B.14
Coca, M.15
Hernandez, A.16
Puig, M.17
Iglesias, M.18
Hernandez, A.19
Ramos, M.20
Rodriquez, L.21
Suarez, N.22
more..
-
104
-
-
36049037819
-
Bevacizumab plus irinotecan in recurrent glioblastoma multiforme
-
DOI 10.1200/JCO.2007.12.2440
-
Vredenburgh JJ, Desjardins A, Herndon 2nd JE, et al. Bevacizumab plus irinotecan in recurrent glioblastoma multiforme. J Clin Oncol. 2007;25(30):4722-9. (Pubitemid 350086473)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.30
, pp. 4722-4729
-
-
Vredenburgh, J.J.1
Desjardins, A.2
Herndon II, J.E.3
Marcello, J.4
Reardon, D.A.5
Quinn, J.A.6
Rich, J.N.7
Sathornsumetee, S.8
Gururangan, S.9
Sampson, J.10
Wagner, M.11
Bailey, L.12
Bigner, D.D.13
Friedman, A.H.14
Friedman, H.S.15
-
105
-
-
34547445550
-
Phase I Trial of Tipifarnib (R115777) Concurrent With Radiotherapy in Patients with Glioblastoma Multiforme
-
DOI 10.1016/j.ijrobp.2007.02.043, PII S0360301607005378
-
Moyal EC, Laprie A, Delannes M, et al. Phase I trial of tipirafinib (R115777) concurrent with radiotherapy in patients with glioblastoma multiforme. Int J Radiat Oncol Biol Phys. 2007;68(5):1396-401. (Pubitemid 47176810)
-
(2007)
International Journal of Radiation Oncology Biology Physics
, vol.68
, Issue.5
, pp. 1396-1401
-
-
Cohen-Jonathan, M.E.1
Laprie, A.2
Delannes, M.3
Poublanc, M.4
Catalaa, I.5
Dalenc, F.6
Berchery, D.7
Sabatier, J.8
Bousquet, P.9
De Porre, P.10
Alaux, B.11
Toulas, C.12
-
106
-
-
34247218483
-
Gefitinib in patients with progressive high-grade gliomas: A multicentre phase II study by Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO)
-
DOI 10.1038/sj.bjc.6603669, PII 6603669
-
Franceschi E, Cavallo G, Lonardi S, et al. Gefitinib in patients with progressive high-grade gliomas: a multicenter phase II study by Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO). Br J Cancer. 2007;96:1047-51. (Pubitemid 46608313)
-
(2007)
British Journal of Cancer
, vol.96
, Issue.7
, pp. 1047-1051
-
-
Franceschi, E.1
Cavallo, G.2
Lonardi, S.3
Magrini, E.4
Tosoni, A.5
Grosso, D.6
Scopece, L.7
Blatt, V.8
Urbini, B.9
Pession, A.10
Tallini, G.11
Crino, L.12
Brandes, A.A.13
-
107
-
-
33747058029
-
Phase II trial of tipifarnib in patients with recurrent malignant glioma either receiving or not receiving enzyme-inducing antiepileptic drugs: A North American Brain Tumor Consortium study
-
DOI 10.1200/JCO.2006.06.2323
-
Cloughesy TF, Wen PY, Robins HI, et al. Phase II trial of tipifarnib in patients with recurrent malignant glioma either receiving or not receiving enzyme-inducing antiepileptic drugs: a North American Brain Tumor Consortium Study. J Clin Oncol. 2006;24(22):3651-6. (Pubitemid 46630540)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.22
, pp. 3651-3656
-
-
Cloughesy, T.F.1
Wen, P.Y.2
Robins, H.I.3
Chang, S.M.4
Groves, M.D.5
Fink, K.L.6
Junck, L.7
Schiff, D.8
Abrey, L.9
Gilbert, M.R.10
Lieberman, F.11
Kuhn, J.12
DeAngelis, L.M.13
Mehta, M.14
Raizer, J.J.15
Yung, W.K.A.16
Aldape, K.17
Wright, J.18
Lamborn, K.R.19
Prados, M.D.20
more..
-
108
-
-
33745793404
-
Randomized, double-blind, placebo-controlled trial of marimastat in glioblastoma multiforme patients following surgery and irradiation
-
DOI 10.1007/s11060-005-9098-5
-
Levin VA, Phuphanich S, Yung WK, et al. Randomized, double-blind, placebo-controlled trial of marimastat in glioblastoma multiforme patients following surgery and irradiation. J Neurooncol. 2006;78(3):295-302. (Pubitemid 44018824)
-
(2006)
Journal of Neuro-Oncology
, vol.78
, Issue.3
, pp. 295-302
-
-
Levin, V.A.1
Phuphanich, S.2
Yung, W.K.A.3
Forsyth, P.A.4
Del, M.R.5
Perry, J.R.6
Fuller, G.N.7
Baillet, M.8
-
109
-
-
33745183568
-
Phase I trial of erlotinib with radiation therapy in patients with glioblastoma multiforme: Results of North Central Cancer Treatment Group protocol N0177
-
Krishnan S, Brown PD, Ballman KV, et al. Phase I trial of erlotinib with radiation therapy in patients with glioblastoma multiforme: results of North Central Cancer Treatment Group protocol N0177. Int J Radiat Oncol Biol Phys. 2006;65(4):1192-9.
-
(2006)
Int J Radiat Oncol Biol Phys
, vol.65
, Issue.4
, pp. 1192-1199
-
-
Krishnan, S.1
Brown, P.D.2
Ballman, K.V.3
-
110
-
-
33646434844
-
Treatment of high-grade glioma patients with the humanized anti-epidermal growth factor receptor (EGFR) antibody h0R3: Report from a phase I/II trial
-
Ramos TC, Figueredo J, Catala M, et al. Treatment of high-grade glioma patients with the humanized anti-epidermal growth factor receptor (EGFR) antibody h0R3: report from a phase I/II trial. Cancer Biol Ther. 2006;5(4):375-9.
-
(2006)
Cancer Biol Ther
, vol.5
, Issue.4
, pp. 375-379
-
-
Ramos, T.C.1
Figueredo, J.2
Catala, M.3
-
111
-
-
31544474851
-
Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma
-
DOI 10.1215/S1522851705000451
-
Prados MD, Lamborn KR, Chang S, et al. Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma. Neuro Oncol. 2006;8(1):67-78. (Pubitemid 43154453)
-
(2006)
Neuro-Oncology
, vol.8
, Issue.1
, pp. 67-78
-
-
Prados, M.D.1
Lamborn, K.R.2
Chang, S.3
Burton, E.4
Butowski, N.5
Malec, M.6
Kapadia, A.7
Rabbit, J.8
Page, M.S.9
Fedoroff, A.10
Xie, D.11
Kelley, S.K.12
-
112
-
-
21044431575
-
Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme
-
DOI 10.1007/s10637-005-1444-0
-
Chang SM, Wen P, Cloughesy T, et al. Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme. Invest New Drugs. 2005;23(4):357-61. (Pubitemid 40980358)
-
(2005)
Investigational New Drugs
, vol.23
, Issue.4
, pp. 357-361
-
-
Chang, S.M.1
Wen, P.2
Cloughesy, T.3
Greenberg, H.4
Schiff, D.5
Conrad, C.6
Fink, K.7
Robins, H.I.8
De Angelis, L.9
Raizer, J.10
Hess, K.11
Aldape, K.12
Lamborn, K.R.13
Kuhn, J.14
Dancey, J.15
Prados, M.D.16
-
113
-
-
23944453425
-
Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: A north central cancer treatment group study
-
DOI 10.1200/JCO.2005.23.622
-
Galanis E, Buckner JC, Maurer MJ, et al. Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: a North Central Cancer Treatment Group Study. J Clin Oncol. 2005;23(23):5294-304. (Pubitemid 46206983)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.23
, pp. 5294-5304
-
-
Galanis, E.1
Buckner, J.C.2
Maurer, M.J.3
Kreisberg, J.I.4
Ballman, K.5
Boni, J.6
Peralba, J.M.7
Jenkins, R.B.8
Dakhil, S.R.9
Morton, R.F.10
Jaeckle, K.A.11
Scheithauer, B.W.12
Dancey, J.13
Hidalgo, M.14
Walsh, D.J.15
-
114
-
-
21444450373
-
Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib
-
DOI 10.1093/jnci/dji161
-
Haas-Kogan DA, Prados MD, Tihan T, et al. Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib. J Natl Cancer Inst. 2005;97(12):880-7. (Pubitemid 41417939)
-
(2005)
Journal of the National Cancer Institute
, vol.97
, Issue.12
, pp. 880-887
-
-
Haas-Kogan, D.A.1
Prados, M.D.2
Tihan, T.3
Eberhard, D.A.4
Jelluma, N.5
Arvold, N.D.6
Baumber, R.7
Lamborn, K.R.8
Kapadia, A.9
Malec, M.10
Berger, M.S.11
Stokoe, D.12
-
115
-
-
1842500007
-
Phase II trial of gefitinib in recurrent glioblastoma
-
DOI 10.1200/JCO.2004.08.110
-
Rich JN, Reardon DA, Peery T, et al. Phase II trial of gefitinib in recurrent glioblastoma. J Clin Oncol. 2004;22(1):133-42. (Pubitemid 41095125)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.1
, pp. 133-142
-
-
Rich, J.N.1
Reardon, D.A.2
Peery, T.3
Dowell, J.M.4
Quinn, J.A.5
Penne, K.L.6
Wikstrand, C.J.7
Van Duyn, L.B.8
Dancey, J.E.9
McLendon, R.E.10
Kao, J.C.11
Stenzel, T.T.12
Rasheed, B.K.A.13
Tourt-Uhlig, S.E.14
Herndon II, J.E.15
Vredenburgh, J.J.16
Sampson, J.H.17
Friedman, A.H.18
Bigner, D.D.19
Friedman, H.S.20
more..
-
116
-
-
0036499078
-
Phase II trial of temozolomide plus the matrix metalloproteinase inhibitor, marimastat, in recurrent and progressive glioblastoma multiforme
-
DOI 10.1200/JCO.20.5.1383
-
Groves MD, Puduvalli VK, Hess KR, et al. Phase II trial of temozolomide plus the matrix metalloproteinase inhibitor, marimastat, in recurrent and progressive glioblastoma multiforme. J Clin Oncol. 2002;20(5):1383-8. (Pubitemid 34177446)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.5
, pp. 1383-1388
-
-
Groves, M.D.1
Puduvalli, V.K.2
Hess, K.R.3
Jaeckle, K.A.4
Peterson, P.5
Yung, W.K.A.6
Levin, V.A.7
-
117
-
-
0029931490
-
Multiple infusions of anti-epidermal growth factor recedptor (EGFR) monoclonal antibody (EMD 55,900) in patients with recurrent malignant gliomas
-
Stragliotto G, Vega F, Stasiecki P, et al. Multiple infusions of anti-epidermal growth factor recedptor (EGFR) monoclonal antibody (EMD 55,900) in patients with recurrent malignant gliomas. Eur J Cancer. 1996;32A(4):636-40.
-
(1996)
Eur J Cancer
, vol.32 A
, Issue.4
, pp. 636-640
-
-
Stragliotto, G.1
Vega, F.2
Stasiecki, P.3
-
118
-
-
0029005809
-
Epidermal growth factor receptor 425 monoclonal antibodies radiolabeled with iodine-125 in the adjuvant treatment of high-grade astrocytomas
-
Snelling L, Miyamoto CT, Bender H, et al. Epidermal growth factor receptor 425 monoclonal antibodies radiolabeled with iodine-125 in the adjuvant treatment of high-grade astrocytomas. Hybridoma. 1995;14(2):111-4.
-
(1995)
Hybridoma
, vol.14
, Issue.2
, pp. 111-114
-
-
Snelling, L.1
Miyamoto, C.T.2
Bender, H.3
-
119
-
-
0026599333
-
Malignant astrocytomas treated with iodine-125 labeled monoclonal antibody 425 against epidermal growth factor receptor: A phase II trial
-
Brady LW, Miyamoto C, Woo DV, et al. Malignant astrocytomas treated with iodine-125 labeled monoclonal antibody 425 against epidermal growth factor receptor: a phase II trial. Int J Radiat Oncol Biol Phys. 1992;22(1):225-30.
-
(1992)
Int J Radiat Oncol Biol Phys
, vol.22
, Issue.1
, pp. 225-230
-
-
Brady, L.W.1
Miyamoto, C.2
Woo, D.V.3
-
120
-
-
84883261716
-
Sorafenib plus daily low-dose temozolomide for relapsed glioblastoma: A phase II study
-
Zustovich F, Landi L, Lombardi G, et al. Sorafenib plus daily low-dose temozolomide for relapsed glioblastoma: a phase II study. Anticancer Res. 2013;33(8):3487-94.
-
(2013)
Anticancer Res
, vol.33
, Issue.8
, pp. 3487-3494
-
-
Zustovich, F.1
Landi, L.2
Lombardi, G.3
-
121
-
-
84876766342
-
Phase II study of bevacizumab and temsirolimus combination therapy for recurrent glioblastoma multiforme
-
Lassen U, Sorensen M, Gaziel TB, et al. Phase II study of bevacizumab and temsirolimus combination therapy for recurrent glioblastoma multiforme. Anticancer Res. 2013;33(4):1657-60.
-
(2013)
Anticancer Res
, vol.33
, Issue.4
, pp. 1657-1660
-
-
Lassen, U.1
Sorensen, M.2
Gaziel, T.B.3
-
122
-
-
84874038379
-
A phase I/II trial of pazopanib in combination with lapatinib in adult patients with relapsed malignant glioma
-
Reardon DA, Groves MD, Wen PY, et al. A phase I/II trial of pazopanib in combination with lapatinib in adult patients with relapsed malignant glioma. Clin Cancer Res. 2013;19(4):900-8.
-
(2013)
Clin Cancer Res
, vol.19
, Issue.4
, pp. 900-908
-
-
Reardon, D.A.1
Groves, M.D.2
Wen, P.Y.3
-
123
-
-
84875740755
-
NABTT 0502: A phase II and pharmacokinetic study of erlotinib and sorafenib for patients with progressive or recurrent glioblastoma multiforme
-
Peereboom DM, Ahluwalia MS, Ye X, et al. NABTT 0502: a phase II and pharmacokinetic study of erlotinib and sorafenib for patients with progressive or recurrent glioblastoma multiforme. Neuro Oncol. 2013;15(4):490-6.
-
(2013)
Neuro Oncol
, vol.15
, Issue.4
, pp. 490-496
-
-
Peereboom, D.M.1
Ahluwalia, M.S.2
Ye, X.3
-
124
-
-
84879300467
-
Phase II open-label study of nintedanib in patients with recurrent glioblastoma multiforme
-
Muhic A, Poulsen HS, Sorensen M, et al. Phase II open-label study of nintedanib in patients with recurrent glioblastoma multiforme. J Neurooncol. 2013;111(2):205-12.
-
(2013)
J Neurooncol
, vol.111
, Issue.2
, pp. 205-212
-
-
Muhic, A.1
Poulsen, H.S.2
Sorensen, M.3
-
125
-
-
84872050000
-
Targeted therapy with bevacizumab and erlotinib tailored to the molecular profile of patients with recurrent glioblastoma. Preliminary experience
-
Wien
-
D'Alessandri QG, Montano N, Cenci T, et al. Targeted therapy with bevacizumab and erlotinib tailored to the molecular profile of patients with recurrent glioblastoma. Preliminary experience. Acta Neurochir (Wien). 2013;155(1):33-40.
-
(2013)
Acta Neurochir
, vol.155
, Issue.1
, pp. 33-40
-
-
D'Alessandri, Q.G.1
Montano, N.2
Cenci, T.3
-
126
-
-
84869155416
-
A phase I/II trial of vandetanib for patients with recurrent malignant glioma
-
Kreisl TN, McNeill KA, Sul J, et al. A phase I/II trial of vandetanib for patients with recurrent malignant glioma. Neuro Oncol. 2012;14(12):1519-26.
-
(2012)
Neuro Oncol
, vol.14
, Issue.12
, pp. 1519-1526
-
-
Kreisl, T.N.1
McNeill, K.A.2
Sul, J.3
-
127
-
-
84869188311
-
Phase I/II study of sorafenib in combination with temsirolimus for recurrent glioblastoma or gliosarcoma: North American Brain Tumor Consortium study 05-02
-
Lee EQ, Kuhn J, Lamborn KR, et al. Phase I/II study of sorafenib in combination with temsirolimus for recurrent glioblastoma or gliosarcoma: North American Brain Tumor Consortium study 05-02. Neuro Oncol. 2012;14(12):1511-8.
-
(2012)
Neuro Oncol
, vol.14
, Issue.12
, pp. 1511-1518
-
-
Lee, E.Q.1
Kuhn, J.2
Lamborn, K.R.3
-
128
-
-
84871816644
-
Continuous daily sunitinib for recurrent glioblastoma
-
Kreisl TN, Smith P, Sul J, et al. Continuous daily sunitinib for recurrent glioblastoma. J Neurooncol. 2013;111(1):41-8.
-
(2013)
J Neurooncol
, vol.111
, Issue.1
, pp. 41-48
-
-
Kreisl, T.N.1
Smith, P.2
Sul, J.3
-
129
-
-
84871818807
-
A phase II study of conventional radiation therapy and thalidomide for supratentorial, newly-diagnosed glioblastoma (RTOG 9806)
-
Alexander BM, Wang M, Yung WK, et al. A phase II study of conventional radiation therapy and thalidomide for supratentorial, newly-diagnosed glioblastoma (RTOG 9806). J Neurooncol. 2013;111(1):33-9.
-
(2013)
J Neurooncol
, vol.111
, Issue.1
, pp. 33-39
-
-
Alexander, B.M.1
Wang, M.2
Yung, W.K.3
-
130
-
-
84867854266
-
A dose escalation trial for the combination of erlotinib and sirolimus for recurrent malignant gliomas
-
Nghiemphu PL, Lai A, Green RM, et al. A dose escalation trial for the combination of erlotinib and sirolimus for recurrent malignant gliomas. J Neurooncol. 2012;110(2):245-50.
-
(2012)
J Neurooncol
, vol.110
, Issue.2
, pp. 245-250
-
-
Nghiemphu, P.L.1
Lai, A.2
Green, R.M.3
-
131
-
-
84866364645
-
A prospective phase II single-institution trial of sunitinib for recurrent malignant glioma
-
Pan E, Yu D, Yue B, et al. A prospective phase II single-institution trial of sunitinib for recurrent malignant glioma. J Neurooncol. 2012;110(1):111-8.
-
(2012)
J Neurooncol
, vol.110
, Issue.1
, pp. 111-118
-
-
Pan, E.1
Yu, D.2
Yue, B.3
-
132
-
-
84859628071
-
Phase II study of concurrent radiation therapy, temozolomide, and bevacizumab followed by bevacizumab/everolimus as first-line treatment for patients with glioblastoma
-
Hainsworth JD, Shih KC, Shepard GC, et al. Phase II study of concurrent radiation therapy, temozolomide, and bevacizumab followed by bevacizumab/everolimus as first-line treatment for patients with glioblastoma. Clin Adv Hematol Oncol. 2012;10(4): 240-6.
-
(2012)
Clin Adv Hematol Oncol
, vol.10
, Issue.4
, pp. 240-246
-
-
Hainsworth, J.D.1
Shih, K.C.2
Shepard, G.C.3
-
133
-
-
84863796631
-
Phase I study of AEE788, a novel multitarget inhibitor of ErbB and VEGF-receptor-family tyrosine kinases, in recurrent glioblastoma patients
-
Reardon DA, Conrad CA, Cloughesy T, et al. Phase I study of AEE788, a novel multitarget inhibitor of ErbB and VEGF-receptor-family tyrosine kinases, in recurrent glioblastoma patients. Cancer Chemother Pharmacol. 2012;69(6):1507-18.
-
(2012)
Cancer Chemother Pharmacol
, vol.69
, Issue.6
, pp. 1507-1518
-
-
Reardon, D.A.1
Conrad, C.A.2
Cloughesy, T.3
-
134
-
-
84859538161
-
Phase II trial of vorinostat in combination with bortezomib in recurrent glioblastoma: A north central cancer treatment group study
-
Friday BB, Anderson SK, Buckner J, et al. Phase II trial of vorinostat in combination with bortezomib in recurrent glioblastoma: a north central cancer treatment group study. Neuro Oncol. 2012;14(2):215-21.
-
(2012)
Neuro Oncol
, vol.14
, Issue.2
, pp. 215-221
-
-
Friday, B.B.1
Anderson, S.K.2
Buckner, J.3
-
135
-
-
84863321033
-
Phase 2 trial of irinotecan and thalidomide in adults with recurrent anaplastic glioma
-
Giglio P, Dhamne M, Hess KR, et al. Phase 2 trial of irinotecan and thalidomide in adults with recurrent anaplastic glioma. Cancer. 2012;118(14):3599-606.
-
(2012)
Cancer
, vol.118
, Issue.14
, pp. 3599-3606
-
-
Giglio, P.1
Dhamne, M.2
Hess, K.R.3
-
136
-
-
84856238982
-
Phase I trial of vorinostat combined with bevacizumab and CPT-11 in recurrent glioblastoma
-
Chinnaiyan P, Chowdhary S, Potthast L, et al. Phase I trial of vorinostat combined with bevacizumab and CPT-11 in recurrent glioblastoma. Neuro Oncol. 2012;14(1):93-100.
-
(2012)
Neuro Oncol
, vol.14
, Issue.1
, pp. 93-100
-
-
Chinnaiyan, P.1
Chowdhary, S.2
Potthast, L.3
-
137
-
-
82955232920
-
Phase I study of sunitinib and irinotecan for patients with recurrent malignant glioma
-
Reardon DA, Vredenburgh JJ, Coan A, et al. Phase I study of sunitinib and irinotecan for patients with recurrent malignant glioma. J Neurooncol. 2011;105(3):621-7.
-
(2011)
J Neurooncol
, vol.105
, Issue.3
, pp. 621-627
-
-
Reardon, D.A.1
Vredenburgh, J.J.2
Coan, A.3
-
138
-
-
79960111080
-
Phase II study of aflibercept in recurrent malignant glioma: A North American Brain Tumor Consortium study
-
De Groot JF, Lamborn KR, Chang SM, et al. Phase II study of aflibercept in recurrent malignant glioma: a North American Brain Tumor Consortium study. J Clin Oncol. 2011;29(19):2689-95.
-
(2011)
J Clin Oncol
, vol.29
, Issue.19
, pp. 2689-2695
-
-
De Groot, J.F.1
Lamborn, K.R.2
Chang, S.M.3
-
139
-
-
79959841782
-
Phase I trial with biomarker studies of vatalanib (PTK787) in patients with newly diagnosed glioblastoma treated with enzyme inducing anti-epileptic drugs and standard radiation and temozolomide
-
Gerstner ER, Eichler AF, Plotkin SR, et al. Phase I trial with biomarker studies of vatalanib (PTK787) in patients with newly diagnosed glioblastoma treated with enzyme inducing anti-epileptic drugs and standard radiation and temozolomide. J Neurooncol. 2011;103(2):325-32.
-
(2011)
J Neurooncol
, vol.103
, Issue.2
, pp. 325-332
-
-
Gerstner, E.R.1
Eichler, A.F.2
Plotkin, S.R.3
-
140
-
-
78650148102
-
A phase I factorial design study of dose-dense temozolomide alone and in combination with thalidomide, isotretinoin, and/or celecoxib as postchemoradiation adjuvant therapy for newly diagnosed glioblastoma
-
Gilbert MR, Gonzalez J, Hunter K, et al. A phase I factorial design study of dose-dense temozolomide alone and in combination with thalidomide, isotretinoin, and/or celecoxib as postchemoradiation adjuvant therapy for newly diagnosed glioblastoma. Neuro Oncol. 2010;12(11):1167-72.
-
(2010)
Neuro Oncol
, vol.12
, Issue.11
, pp. 1167-1172
-
-
Gilbert, M.R.1
Gonzalez, J.2
Hunter, K.3
-
141
-
-
78650102866
-
Phase II trial of bevacizumab and erlotinib in patients with recurrent malignant glioma
-
Sathornsumetee S, Dejardins A, Vredenburgh JJ, et al. Phase II trial of bevacizumab and erlotinib in patients with recurrent malignant glioma. Neuro Oncol. 2010;12(12):1300-10.
-
(2010)
Neuro Oncol
, vol.12
, Issue.12
, pp. 1300-1310
-
-
Sathornsumetee, S.1
Dejardins, A.2
Vredenburgh, J.J.3
-
142
-
-
77955363593
-
Concurrent radiotherapy and temozolomide followed by temozolomide and sorafenib in the first-line treatment of patients with glioblastoma multiforme
-
Hainsworth JD, Ervin T, Friedman E, et al. Concurrent radiotherapy and temozolomide followed by temozolomide and sorafenib in the first-line treatment of patients with glioblastoma multiforme. Cancer. 2010;116(15):3663-9.
-
(2010)
Cancer
, vol.116
, Issue.15
, pp. 3663-3669
-
-
Hainsworth, J.D.1
Ervin, T.2
Friedman, E.3
-
143
-
-
77954748580
-
Cetuximab, bevacizumab, and irinotecan for patients with primary glioblastoma and progression after radiation therapy and temozolomide: A phase II trial
-
Hasselbalch B, Lassen U, Hansen S, et al. Cetuximab, bevacizumab, and irinotecan for patients with primary glioblastoma and progression after radiation therapy and temozolomide: a phase II trial. Neuro Oncol. 2010;12(5):508-16.
-
(2010)
Neuro Oncol
, vol.12
, Issue.5
, pp. 508-516
-
-
Hasselbalch, B.1
Lassen, U.2
Hansen, S.3
-
144
-
-
77749332056
-
A phase 1 trial of ABT-510 concurrent with standard chemoradiation for patients with newly diagnosed glioblastoma
-
Nabors LB, Fiveash JB, Markert JM, et al. A phase 1 trial of ABT-510 concurrent with standard chemoradiation for patients with newly diagnosed glioblastoma. Arch Neurol. 2010;67(3):313-9.
-
(2010)
Arch Neurol
, vol.67
, Issue.3
, pp. 313-319
-
-
Nabors, L.B.1
Fiveash, J.B.2
Markert, J.M.3
-
145
-
-
78149492402
-
Phase II trial of pazopanib (GW786034), an oral multi-targeted angiogenesis inhibitor, for adults with recurrent glioblastoma (North American Brain Tumor Consortium Study 06-02)
-
Iwamoto FM, Lamborn KR, Robins HI, et al. Phase II trial of pazopanib (GW786034), an oral multi-targeted angiogenesis inhibitor, for adults with recurrent glioblastoma (North American Brain Tumor Consortium Study 06-02). Neuro Oncol. 2010;12(8):8555-61.
-
(2010)
Neuro Oncol
, vol.12
, Issue.8
, pp. 8555-8561
-
-
Iwamoto, F.M.1
Lamborn, K.R.2
Robins, H.I.3
-
146
-
-
77955922743
-
Phase I study of vandetanib with radiotherapy and temozolomide for newly diagnosed glioblastoma
-
Drappatz J, Norden AD, Wong ET, et al. Phase I study of vandetanib with radiotherapy and temozolomide for newly diagnosed glioblastoma. Int J Radiat Oncol Biol Phys. 2010;78(1):85-90.
-
(2010)
Int J Radiat Oncol Biol Phys
, vol.78
, Issue.1
, pp. 85-90
-
-
Drappatz, J.1
Norden, A.D.2
Wong, E.T.3
-
147
-
-
72449155176
-
EORTC study 26041-22041: Phase I/II study on concomitant and adjuvant temozolomide (TMZ) and radiotherapy (RT) with PTK787/ZK222584 (PTK/ZK) in newly diagnosed glioblastoma
-
Brandes AA, Stupp R, Hau P, et al. EORTC study 26041-22041: phase I/II study on concomitant and adjuvant temozolomide (TMZ) and radiotherapy (RT) with PTK787/ZK222584 (PTK/ZK) in newly diagnosed glioblastoma. Eur J Cancer. 2010;46(2):348-54.
-
(2010)
Eur J Cancer
, vol.46
, Issue.2
, pp. 348-354
-
-
Brandes, A.A.1
Stupp, R.2
Hau, P.3
-
148
-
-
71649102124
-
Multicentre phase II studies evaluating imatinib plus hydroxyurea in patients with progressive glioblastoma
-
Reardon DA, Dresemann G, Taillibert S, et al. Multicentre phase II studies evaluating imatinib plus hydroxyurea in patients with progressive glioblastoma. Br J Cancer. 2009;101(12):1995-2004.
-
(2009)
Br J Cancer
, vol.101
, Issue.12
, pp. 1995-2004
-
-
Reardon, D.A.1
Dresemann, G.2
Taillibert, S.3
-
149
-
-
70349694368
-
Phase II study of neoadjuvant imatinib in glioblastoma: Evaluation of clinical and molecular effects of the treatment
-
Razis E, Selviaridis P, Labropoulos S, et al. Phase II study of neoadjuvant imatinib in glioblastoma: evaluation of clinical and molecular effects of the treatment. Clin Cancer Res. 2009;15(19): 6258-66.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.19
, pp. 6258-6266
-
-
Razis, E.1
Selviaridis, P.2
Labropoulos, S.3
-
150
-
-
75049085049
-
Imatinib in combination with hydroxyurea versus hydroxyurea alone as oral therapy in patients with progressive pretreated glioblastoma resistant to standard dose temozolomide
-
Dresemann G, Weller M, Rosenthal MA, et al. Imatinib in combination with hydroxyurea versus hydroxyurea alone as oral therapy in patients with progressive pretreated glioblastoma resistant to standard dose temozolomide. J Neurooncol. 2010;96(3):393-402.
-
(2010)
J Neurooncol
, vol.96
, Issue.3
, pp. 393-402
-
-
Dresemann, G.1
Weller, M.2
Rosenthal, M.A.3
-
151
-
-
75049084471
-
Phase 2 trial of erlotinib plus sirolimus in adults with recurrent glioblastoma
-
Reardon DA, Desjardin A, Vredenburgh JJ, et al. Phase 2 trial of erlotinib plus sirolimus in adults with recurrent glioblastoma. J Neurooncol. 2010;96(2):219-30.
-
(2010)
J Neurooncol
, vol.96
, Issue.2
, pp. 219-230
-
-
Reardon, D.A.1
Desjardin, A.2
Vredenburgh, J.J.3
-
152
-
-
65649146868
-
Phase I pharmacokinetic study of the vascular endothelial growth factor receptor tyrosine kinase inhibitor vatalanib (PTK787) plus imatinib and hydroxyurea for malignant glioma
-
Reardon DA, Egorin MJ, Desjardins A, et al. Phase I pharmacokinetic study of the vascular endothelial growth factor receptor tyrosine kinase inhibitor vatalanib (PTK787) plus imatinib and hydroxyurea for malignant glioma. Cancer. 2009;115(10):2188-98.
-
(2009)
Cancer
, vol.115
, Issue.10
, pp. 2188-2198
-
-
Reardon, D.A.1
Egorin, M.J.2
Desjardins, A.3
-
153
-
-
59349089499
-
A pilot study of everolimus and gefitinib in the treatment of recurrent glioblastoma (GBM)
-
Kreisl TN, Lassman AB, Mischel PS, et al. A pilot study of everolimus and gefitinib in the treatment of recurrent glioblastoma (GBM). J Neurooncol. 2009;92(1):99-105.
-
(2009)
J Neurooncol
, vol.92
, Issue.1
, pp. 99-105
-
-
Kreisl, T.N.1
Lassman, A.B.2
Mischel, P.S.3
-
154
-
-
53349117686
-
A phase II study of thalidomide and irinotecan for treatment of glioblastoma multiforme
-
Fadul CE, Kingman LS, Meyer LP, et al. A phase II study of thalidomide and irinotecan for treatment of glioblastoma multiforme. J Neurooncol. 2008;90(2):229-35.
-
(2008)
J Neurooncol
, vol.90
, Issue.2
, pp. 229-235
-
-
Fadul, C.E.1
Kingman, L.S.2
Meyer, L.P.3
-
155
-
-
57649110848
-
A pilot safety study of lenalidomide and radiotherapy for patients with newly diagnosed glioblastoma multiforme
-
Drappatz J, Wong ET, Schiff D, et al. A pilot safety study of lenalidomide and radiotherapy for patients with newly diagnosed glioblastoma multiforme. Int J Radiat Oncol Phys. 2009;73(1):222-7.
-
(2009)
Int J Radiat Oncol Phys
, vol.73
, Issue.1
, pp. 222-227
-
-
Drappatz, J.1
Wong, E.T.2
Schiff, D.3
-
156
-
-
55849093794
-
Phase II study of temozolomide, thalidomide, and celecoxib for newly diagnosed glioblastoma in adults
-
Kesari S, Schiff D, Henson JW, et al. Phase II study of temozolomide, thalidomide, and celecoxib for newly diagnosed glioblastoma in adults. Neuro Oncol. 2008;10(3):300-8.
-
(2008)
Neuro Oncol
, vol.10
, Issue.3
, pp. 300-308
-
-
Kesari, S.1
Schiff, D.2
Henson, J.W.3
-
157
-
-
45349093651
-
Safety and pharmacokinetics of dose-intensive imatinib mesylate plus temozolomide: Phase 1 trial in adults with malignant glioma
-
Reardon DA, Desjardins A, Vredenburgh JJ, et al. Safety and pharmacokinetics of dose-intensive imatinib mesylate plus temozolomide: phase 1 trial in adults with malignant glioma. Neuro Oncol. 2008;10(3):330-40.
-
(2008)
Neuro Oncol
, vol.10
, Issue.3
, pp. 330-340
-
-
Reardon, D.A.1
Desjardins, A.2
Vredenburgh, J.J.3
-
158
-
-
44849144705
-
Phase II trial of irinotecan and thalidomide in adults with recurrent glioblastoma multiforme
-
Puduvalli VK, Giglio P, Groves MD, et al. Phase II trial of irinotecan and thalidomide in adults with recurrent glioblastoma multiforme. Neuro Oncol. 2008;10(2):216-22.
-
(2008)
Neuro Oncol
, vol.10
, Issue.2
, pp. 216-222
-
-
Puduvalli, V.K.1
Giglio, P.2
Groves, M.D.3
-
159
-
-
37249075870
-
A phase I trial of lenalidomide in patients with recurrent primary central nervous system tumors
-
DOI 10.1158/1078-0432.CCR-07-1546
-
Fine HA, Kim L, Albert PS, et al. A phase I trial of lenalidomide in patients with recurrent primary central nervous system tumors. Clin Cancer Res. 2007;13(23):7101-6. (Pubitemid 350276894)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.23
, pp. 7101-7106
-
-
Fine, H.A.1
Kim, L.2
Albert, P.S.3
Duic, J.P.4
Ma, H.5
Zhang, W.6
Tohnya, T.7
Figg, W.D.8
Royce, C.9
-
160
-
-
34247166361
-
A phase I study of cisplatin, temozolomide and thalidomide in patients with malignant brain tumors
-
Zustovich F, Cartei G, Ceravolo R, et al. A phase I study of cisplatin, temozolomide and thalidomide in patients with malignant brain tumors. Anticancer Res. 2007;27(2):1019-24. (Pubitemid 46587016)
-
(2007)
Anticancer Research
, vol.27
, Issue.2
, pp. 1019-1024
-
-
Zustovich, F.1
Cartei, G.2
Ceravolo, R.3
Zovato, S.4
Della, P.A.5
Pastorelli, D.6
Mattiazzi, M.7
Bertorelle, R.8
Gardiman, M.P.9
-
161
-
-
34247476830
-
Phase II study of imatinib mesylate and hydroxyurea for recurrent grade III malignant gliomas
-
DOI 10.1007/s11060-006-9302-2
-
Desjardins A, Quinn JA, Vredenburgh JJ, et al. Phase II study of imatinib mesylate and hydroxyurea for recurrent grade III malignant gliomas. J Neurooncol. 2007;83(1):53-60. (Pubitemid 46647165)
-
(2007)
Journal of Neuro-Oncology
, vol.83
, Issue.1
, pp. 53-60
-
-
Desjardins, A.1
Quinn, J.A.2
Vredenburgh, J.J.3
Sathornsumetee, S.4
Friedman, A.H.5
Herndon, J.E.6
McLendon, R.E.7
Provenzale, J.M.8
Rich, J.N.9
Sampson, J.H.10
Gururangan, S.11
Dowell, J.M.12
Salvado, A.13
Friedman, H.S.14
Reardon, D.A.15
-
162
-
-
33846495120
-
A North American brain tumor consortium (NABTC 99-04) phase II trial of temozolomide plus thalidomide for recurrent glioblastoma multiforme
-
DOI 10.1007/s11060-006-9225-y
-
Groves MD, Puduvalli VK, Chang SM, et al. A North American brain tumor consortium (NABTC 99-04) phase II trial of temozolomide plus thalidomide for recurrent glioblastoma multiforme. J Neurooncol. 2007;81(3):271-7. (Pubitemid 46165331)
-
(2007)
Journal of Neuro-Oncology
, vol.81
, Issue.3
, pp. 271-277
-
-
Groves, M.D.1
Puduvalli, V.K.2
Chang, S.M.3
Conrad, C.A.4
Gilbert, M.R.5
Tremont-Lukats, I.W.6
Liu, T.-J.7
Peterson, P.8
Schiff, D.9
Cloughesy, T.F.10
Wen, P.Y.11
Greenberg, H.12
Abrey, L.E.13
DeAngelis, L.M.14
Hess, K.R.15
Lamborn, K.R.16
Prados, M.D.17
Yung, A.W.K.18
-
163
-
-
33748376520
-
Phase I/II study of imatinib mesylate for recurrent malignant gliomas: North American Brain Tumor Consortium Study 99-08
-
DOI 10.1158/1078-0432.CCR-06-0773
-
Wen PY, Yung WK, Lamborn KR, et al. Phase I/II study of imatinib mesylate for recurrent malignant gliomas: North American Brain Tumor Consortium Study 99-08. Clin Cancer Res. 2006;12(16): 4899-907. (Pubitemid 44338577)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.16
, pp. 4899-4907
-
-
Wen, P.Y.1
Yung, W.K.A.2
Lamborn, K.R.3
Dahia, P.L.4
Wang, Y.5
Peng, B.6
Abrey, L.E.7
Raizer, J.8
Cloughesy, T.F.9
Fink, K.10
Gilbert, M.11
Chang, S.12
Junck, L.13
Schiff, D.14
Lieberman, F.15
Fine, H.A.16
Mehta, M.17
Robins, H.I.18
DeAngelis, L.M.19
Groves, M.D.20
Puduvalli, V.K.21
Levin, V.22
Conrad, C.23
Maher, E.A.24
Aldape, K.25
Hayes, M.26
Letvak, L.27
Egorin, M.J.28
Capdeville, R.29
Kaplan, R.30
Murgo, A.J.31
Stiles, C.32
Prados, M.D.33
more..
-
164
-
-
32944478030
-
Phase 1 trial of gefitinib plus sirolimus in adults with recurrent malignant glioma
-
DOI 10.1158/1078-0432.CCR-05-2215
-
Reardon DA, Quinn JA, Vredenburgh JJ, et al. Phase I trial of gefitinib plus sirolimus in adults with recurrent malignant glioma. Clin Cancer Res. 2006;12(3 Pt 1):860-8. (Pubitemid 43259869)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.3 I
, pp. 860-868
-
-
Reardon, D.A.1
Quinn, J.A.2
Vredenburgh, J.J.3
Gururangan, S.4
Friedman, A.H.5
Desjardins, A.6
Sathornsumetee, S.7
Herndon II, J.E.8
Dowell, J.M.9
McLendon, R.E.10
Provenzale, J.M.11
Sampson, J.H.12
Smith, R.P.13
Swaisland, A.J.14
Ochs, J.S.15
Lyons, P.16
Tourt-Uhlig, S.17
Bigner, D.D.18
Friedman, H.S.19
Rich, J.N.20
more..
-
165
-
-
33644830094
-
Phase II study of imatinib mesylate plus hydroxyurea in adults with recurrent glioblastoma multiforme
-
Reardon DA, Egorin MJ, Quinn JA, et al. Phase II study of imatinib mesylate plus hydroxyurea in adults with recurrent glioblastoma multiforme. J Clin Oncol. 2005;23(36):9359-68.
-
(2005)
J Clin Oncol
, vol.23
, Issue.36
, pp. 9359-9368
-
-
Reardon, D.A.1
Egorin, M.J.2
Quinn, J.A.3
-
166
-
-
4544289953
-
Phase II study of temozolomide and thalidomide with radiation therapy for newly diagnosed glioblastoma multiforme
-
DOI 10.1016/j.ijrobp.2004.04.023, PII S0360301604006571
-
Chang SM, Lamborn KR, Malec M, et al. Phase II study of temozolomide and thalidomide with radiation therapy for newly diagnosed glioblastoma multiforme. Int J Radiat Oncol Biol Phys. 2004;60(2):353-7. (Pubitemid 39233451)
-
(2004)
International Journal of Radiation Oncology Biology Physics
, vol.60
, Issue.2
, pp. 353-357
-
-
Chang, S.M.1
Lamborn, K.R.2
Malec, M.3
Larson, D.4
Wara, W.5
Sneed, P.6
Rabbitt, J.7
Page, M.8
Nicholas, M.K.9
Prados, M.D.10
-
167
-
-
1842536794
-
Combined thalidomide and temozolomide treatment in patients with glioblastoma multiforme
-
DOI 10.1023/B:NEON.0000021803.01170.03
-
Baumann F, Bjeljac M, Kollias SS, et al. Combined thalidomide and temozolomide treatment in patients with glioblastoma multiforme. J Neurooncol. 2004;67(1-2):191-200. (Pubitemid 38418268)
-
(2004)
Journal of Neuro-Oncology
, vol.67
, Issue.1-2
, pp. 191-200
-
-
Baumann, F.1
Bjeljac, M.2
Kollias, S.S.3
Baumert, B.G.4
Brandner, S.5
Rousson, V.6
Yonekawa, Y.7
Bernays, R.L.8
-
168
-
-
3543132551
-
Thalidomide prolongs disease stabilization after conventional therapy in patients with recurrent glioblastoma
-
Morabito A, Fanelli M, Carillio G, et al. Thalidomide prolongs disease stabilization after conventional therapy in patients with recurrent glioblastoma. Oncol Rep. 2004;11(1):93-5.
-
(2004)
Oncol Rep
, vol.11
, Issue.1
, pp. 93-95
-
-
Morabito, A.1
Fanelli, M.2
Carillio, G.3
-
169
-
-
0037811745
-
Phase II trial of thalidomide and carmustine for patients with recurrent high-grade gliomas
-
DOI 10.1200/JCO.2003.08.045
-
Fine HA, Wen PY, Maher EA, et al. Phase II trial of thalidomide and carmustine for patients with recurrent high-grade gliomas. J Clin Oncol. 2003;21(12):2299-304. (Pubitemid 46621867)
-
(2003)
Journal of Clinical Oncology
, vol.21
, Issue.12
, pp. 2299-2304
-
-
Fine, H.A.1
Wen, P.Y.2
Maher, E.A.3
Viscosi, E.4
Batchelor, T.5
Lakhani, N.6
Figg, W.D.7
Purow, B.W.8
Borkowf, C.B.9
-
170
-
-
0035191268
-
Phase II study of Thalidomide in the treatment of recurrent glioblastoma multiforme
-
DOI 10.1023/A:1012554328801
-
Marx GM, Pavlakis N, McCowatt S, et al. Phase II study of thalidomide in the treatment of recurrent glioblastoma multiforme. J Neurooncol. 2001;54(1):31-8. (Pubitemid 33089257)
-
(2001)
Journal of Neuro-Oncology
, vol.54
, Issue.1
, pp. 31-38
-
-
Marx, G.M.1
Pavlakis, N.2
McCowatt, S.3
Boyle, F.M.4
Levi, J.A.5
Bell, D.R.6
Cook, R.7
Biggs, M.8
Little, N.9
Wheeler, H.R.10
-
171
-
-
0033954292
-
Phase II trial of the antiangiogenic agent thalidomide in patients with recurrent high-grade gliomas
-
Fine HA, Figg WD, Jaeckle K, et al. Phase II trial of the antiangiogenic agent thalidomide in patients with recurrent high-grade gliomas. J Clin Oncol. 2000;18(4):708-15. (Pubitemid 30106600)
-
(2000)
Journal of Clinical Oncology
, vol.18
, Issue.4
, pp. 708-715
-
-
Fine, H.A.1
Figg, W.D.2
Jaeckle, K.3
Wen, P.Y.4
Kyritsis, A.P.5
Loeffler, J.S.6
Levin, V.A.7
Black, P.M.8
Kaplan, R.9
Pluda, J.M.10
Yung, W.K.A.11
-
172
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Cancer Genome Atlas Research Network
-
Cancer Genome Atlas Research Network. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature. 2008;455:1061-8.
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
173
-
-
0036141447
-
Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling
-
Chakravarti A, Loeffler JS, Dyson NJ. Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling. Cancer Res. 2002;62(1):200-7. (Pubitemid 34074005)
-
(2002)
Cancer Research
, vol.62
, Issue.1
, pp. 200-207
-
-
Chakravarti, A.1
Loeffler, J.S.2
Dyson, N.J.3
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