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Volumn 124, Issue , 2014, Pages 187-193

Interactions of ruthenium complexes containing indoloquinoline moiety with human telomeric G-quadruplex DNA

Author keywords

G quadruplex; Indoloquinoline; Ruthenium complex; Telomere

Indexed keywords

1 ,10-PHENANTHROLINE; CIRCULAR DICHROISM SPECTRA; G-QUADRUPLEX STRUCTURE; G-QUADRUPLEXES; INDOLOQUINOLINE; RUTHENIUM COMPLEXES; STACKING INTERACTION; TELOMERES;

EID: 84893168275     PISSN: 13861425     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.saa.2013.12.096     Document Type: Article
Times cited : (19)

References (55)
  • 2
    • 34249907843 scopus 로고    scopus 로고
    • Non-B DNA conformations, mutagenesis and disease
    • DOI 10.1016/j.tibs.2007.04.003, PII S0968000407000916
    • R.D. Wells Non-B DNA conformations, mutagenesis and disease Trends Biochem. Sci. 32 2007 271 278 (Pubitemid 46874927)
    • (2007) Trends in Biochemical Sciences , vol.32 , Issue.6 , pp. 271-278
    • Wells, R.D.1
  • 3
    • 66149136847 scopus 로고    scopus 로고
    • Discovery of the role of non-B DNA structures in mutagenesis and human genomic disorders
    • R.D. Wells Discovery of the role of non-B DNA structures in mutagenesis and human genomic disorders J. Biol. Chem. 14 2009 8997 9009
    • (2009) J. Biol. Chem. , vol.14 , pp. 8997-9009
    • Wells, R.D.1
  • 4
    • 45749103733 scopus 로고    scopus 로고
    • Four-stranded nucleic acids: Structure, function and targeting of G-quadruplexes
    • J.L. Huppert Four-stranded nucleic acids: structure, function and targeting of G-quadruplexes Chem. Soc. Rev. 37 2008 1375 1384
    • (2008) Chem. Soc. Rev. , vol.37 , pp. 1375-1384
    • Huppert, J.L.1
  • 5
    • 84867744921 scopus 로고    scopus 로고
    • DNA secondary structures: Stability and function of G-quadruplex structures
    • M.L. Bochman, K. Paeschke, and V.A. Zakian DNA secondary structures: stability and function of G-quadruplex structures Nat. Rev. Genet. 13 2012 770 780
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 770-780
    • Bochman, M.L.1    Paeschke, K.2    Zakian, V.A.3
  • 6
    • 0025731583 scopus 로고
    • Structure and function of telomeres
    • E.H. Blackburn Structure and function of telomeres Nature 350 1991 569 573 (Pubitemid 21912269)
    • (1991) Nature , vol.350 , Issue.6319 , pp. 569-573
    • Blackburn, E.H.1
  • 8
    • 0032030327 scopus 로고    scopus 로고
    • DNA tetraplex formation in the control region of c-myc
    • DOI 10.1093/nar/26.5.1167
    • T. Simonsson, P. Pecinka, and M. Kubista DNA tetraplex formation in the control region of c-myc Nucleic Acids Res. 26 1998 1167 1172 (Pubitemid 28291685)
    • (1998) Nucleic Acids Research , vol.26 , Issue.5 , pp. 1167-1172
    • Simonsson, T.1    Pecinka, P.2    Kubista, M.3
  • 9
    • 0023788886 scopus 로고
    • Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis
    • D. Sen, and W. Gilbert Formation of parallel four-stranded complexes by guanine-rich motifs in DNA and its implications for meiosis Nature 334 1988 364 366
    • (1988) Nature , vol.334 , pp. 364-366
    • Sen, D.1    Gilbert, W.2
  • 11
    • 80053083464 scopus 로고    scopus 로고
    • Contribution of telomere G-quadruplex stabilization to the inhibition of telomerase-mediated telomere extension by chemical ligands
    • C.Y. Chen, Q. Wang, J.Q. Liu, Y.H. Hao, and Z. Tan Contribution of telomere G-quadruplex stabilization to the inhibition of telomerase-mediated telomere extension by chemical ligands J. Am. Chem. Soc. 133 2011 15036 15044
    • (2011) J. Am. Chem. Soc. , vol.133 , pp. 15036-15044
    • Chen, C.Y.1    Wang, Q.2    Liu, J.Q.3    Hao, Y.H.4    Tan, Z.5
  • 14
    • 80052532707 scopus 로고    scopus 로고
    • G4-DNA formation in the HRAS promoter and rational design of decoy oligonucleotides for cancer therapy
    • A. Membrino1, S. Cogoi1, E.B. Pedersen, and L.E. Xodo G4-DNA formation in the HRAS promoter and rational design of decoy oligonucleotides for cancer therapy PLoS ONE 6 2011 e24421
    • (2011) PLoS ONE , vol.6 , pp. 24421
    • Membrino, A.1    Cogoi, S.2    Pedersen, E.B.3    Xodo, L.E.4
  • 15
    • 35848942604 scopus 로고    scopus 로고
    • Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: Small molecule regulation of c-kit oncogene expression
    • DOI 10.1021/ja075881p
    • M. Bejugam, S. Sewitz, P.S. Shirude, R. Rodriguez, R. Shahid, and S. Balasubramanian Trisubstituted isoalloxazines as a new class of G-quadruplex binding ligands: small molecule regulation of c-kit oncogene expression J. Am. Chem. Soc. 129 2007 12926 12927 (Pubitemid 350058320)
    • (2007) Journal of the American Chemical Society , vol.129 , Issue.43 , pp. 12926-12927
    • Bejugam, M.1    Sewitz, S.2    Shirude, P.S.3    Rodriguez, R.4    Shahid, R.5    Balasubramanian, S.6
  • 16
    • 84871549886 scopus 로고    scopus 로고
    • Convenient method for the synthesis of a flexible cyclic polyamide for selective targeting of c-myb G-quadruplex DNA
    • Q. Zhang, X.J. Cui, S. Lin, J. Zhou, and Y. Gu Convenient method for the synthesis of a flexible cyclic polyamide for selective targeting of c-myb G-quadruplex DNA Org. Lett. 14 2012 6126 6129
    • (2012) Org. Lett. , vol.14 , pp. 6126-6129
    • Zhang, Q.1    Cui, X.J.2    Lin, S.3    Zhou, J.4    Gu, Y.5
  • 18
    • 67349242330 scopus 로고    scopus 로고
    • Metal complexes as structure-selective binding agents for nucleic acids
    • F.R. Keene, J.A. Smith, and J.G. Collins Metal complexes as structure-selective binding agents for nucleic acids Coord. Chem. Rev. 253 2009 2021 2035
    • (2009) Coord. Chem. Rev. , vol.253 , pp. 2021-2035
    • Keene, F.R.1    Smith, J.A.2    Collins, J.G.3
  • 19
    • 84855536627 scopus 로고    scopus 로고
    • Selective G-quadruplex DNA stabilizing agents based on bisquinolinium and bispyridinium derivatives of 1,8-naphthyridine
    • V. Dhamodharan, S. Harikrishna, C. Jagadeeswaran, K. Halder, and P.I. Pradeepkumar Selective G-quadruplex DNA stabilizing agents based on bisquinolinium and bispyridinium derivatives of 1,8-naphthyridine J. Org. Chem. 77 2012 229 242
    • (2012) J. Org. Chem. , vol.77 , pp. 229-242
    • Dhamodharan, V.1    Harikrishna, S.2    Jagadeeswaran, C.3    Halder, K.4    Pradeepkumar, P.I.5
  • 21
    • 84859788948 scopus 로고    scopus 로고
    • Dimeric 1,3-phenylene-bis(piperazinyl benzimidazole)s: Synthesis and structure-activity investigations on their binding with human telomeric G-quadruplex DNA and telomerase inhibition properties
    • A.K. Jain, A. Paul, B. Maji, K. Muniyappa, and S. Bhattacharya Dimeric 1,3-phenylene-bis(piperazinyl benzimidazole)s: Synthesis and structure-activity investigations on their binding with human telomeric G-quadruplex DNA and telomerase inhibition properties J. Med. Chem. 55 2012 2981 2993
    • (2012) J. Med. Chem. , vol.55 , pp. 2981-2993
    • Jain, A.K.1    Paul, A.2    Maji, B.3    Muniyappa, K.4    Bhattacharya, S.5
  • 22
    • 84862587840 scopus 로고    scopus 로고
    • Spectroscopic, molecular modeling and NMR-spectroscopic investigation of the binding mode of the natural alkaloids berberine and sanguinarine to human telomeric G-quadruplex DNA
    • I. Bessi, C. Bazzicalupi, C. Richter, H.R.A. Jonker, K. Saxena, C. Sissi, M. Chioccioli, S. Bianco, A.R. Bilia, H. Schwalbe, and P. Gratteri Spectroscopic, molecular modeling and NMR-spectroscopic investigation of the binding mode of the natural alkaloids berberine and sanguinarine to human telomeric G-quadruplex DNA ACS Chem. Biol. 7 2012 1109 1119
    • (2012) ACS Chem. Biol. , vol.7 , pp. 1109-1119
    • Bessi, I.1    Bazzicalupi, C.2    Richter, C.3    Jonker, H.R.A.4    Saxena, K.5    Sissi, C.6    Chioccioli, M.7    Bianco, S.8    Bilia, A.R.9    Schwalbe, H.10    Gratteri, P.11
  • 23
    • 84864598071 scopus 로고    scopus 로고
    • Interaction between the heme and a G-quartet in a heme-DNA complex
    • K. Saito, H. Tai, H. Hemmi, N. Kobayashi, and Y. Yamamoto Interaction between the heme and a G-quartet in a heme-DNA complex Inorg. Chem. 51 2012 8168 8176
    • (2012) Inorg. Chem. , vol.51 , pp. 8168-8176
    • Saito, K.1    Tai, H.2    Hemmi, H.3    Kobayashi, N.4    Yamamoto, Y.5
  • 24
    • 31544441946 scopus 로고    scopus 로고
    • Senescence and telomere shortening induced by novel potent G-quadruplex interactive agents, quindoline derivatives, in human cancer cell lines
    • DOI 10.1038/sj.onc.1209067, PII 1209067
    • J.M. Zhou, X.F. Zhu, Y.J. Lu, Z.S. Huang, Y.P. Mei, Y. Wang, W.L. Huang, Z.C. Liu, and L.Q. Gu Senescence and telomere shortening induced by novel potent G-quadruplex interactive agents, quindoline derivatives, in human cancer cell lines Oncogene 25 2006 503 511 (Pubitemid 43164461)
    • (2006) Oncogene , vol.25 , Issue.4 , pp. 503-511
    • Zhou, J.-M.1    Zhu, X.-F.2    Lu, Y.-J.3    Deng, R.4    Huang, Z.-S.5    Mei, Y.-P.6    Wang, Y.7    Huang, W.-L.8    Liu, Z.-C.9    Gu, L.-Q.10    Zeng, Y.-X.11
  • 25
    • 80051910937 scopus 로고    scopus 로고
    • Inhibition of cell proliferation by quindoline derivative (SYUIQ-05) through its preferential interaction with c-myc promoter G-quadruplex
    • T.M. Ou, J. Lin, Y.J. Lu, J.Q. Hou, S.H. Chen, Z. Li, Y.P. Li, L.Q. Gu, and Z.S. Huang Inhibition of cell proliferation by quindoline derivative (SYUIQ-05) through its preferential interaction with c-myc promoter G-quadruplex J. Med. Chem. 54 2011 5671 5679
    • (2011) J. Med. Chem. , vol.54 , pp. 5671-5679
    • Ou, T.M.1    Lin, J.2    Lu, Y.J.3    Hou, J.Q.4    Chen, S.H.5    Li, Z.6    Li, Y.P.7    Gu, L.Q.8    Huang, Z.S.9
  • 26
    • 80455123924 scopus 로고    scopus 로고
    • Solution structure of a 2:1 quindoline-c-MYC G-Quadruplex: Insights into G-Quadruplex-Interactive Small Molecule Drug Design
    • J.X. Dai, M. Carver, L.H. Hurley, and D.Z. Yang Solution structure of a 2:1 quindoline-c-MYC G-Quadruplex: Insights into G-Quadruplex-Interactive Small Molecule Drug Design J. Am. Chem. Soc. 133 2011 17673 17680
    • (2011) J. Am. Chem. Soc. , vol.133 , pp. 17673-17680
    • Dai, J.X.1    Carver, M.2    Hurley, L.H.3    Yang, D.Z.4
  • 27
    • 79952735877 scopus 로고    scopus 로고
    • Studies on the binding of 5-N-methylated quindoline derivative to human telomeric G-quadruplex
    • W. Xu, J.H. Tan, S.B. Chen, J.Q. Hou, D. Li, Z.S. Huang, and L.Q. Gu Studies on the binding of 5-N-methylated quindoline derivative to human telomeric G-quadruplex Biochem. Biophys. Res. Commun. 406 2011 454 458
    • (2011) Biochem. Biophys. Res. Commun. , vol.406 , pp. 454-458
    • Xu, W.1    Tan, J.H.2    Chen, S.B.3    Hou, J.Q.4    Li, D.5    Huang, Z.S.6    Gu, L.Q.7
  • 32
    • 84863659642 scopus 로고    scopus 로고
    • Polypyridyl complexes of Ruthenium(II): Stabilization of G-quadruplex DNA and inhibition of telomerase activity
    • D. Liu, Y.N. Liu, C. Wang, S. Shi, D.D. Sun, F. Gao, Q.L. Zhang, and J. Liu Polypyridyl complexes of Ruthenium(II): stabilization of G-quadruplex DNA and inhibition of telomerase activity ChemPlusChem 77 2012 551 562
    • (2012) ChemPlusChem , vol.77 , pp. 551-562
    • Liu, D.1    Liu, Y.N.2    Wang, C.3    Shi, S.4    Sun, D.D.5    Gao, F.6    Zhang, Q.L.7    Liu, J.8
  • 33
    • 84870860613 scopus 로고    scopus 로고
    • Chiral ruthenium(II) polypyridyl complexes: Stabilization of G-quadruplex DNA, inhibition of telomerase activity and cellular uptake
    • Q.Q. Yu, Y.N. Liu, C. Wang, D.D. Sun, X.C. Yang, Y.Y. Liu, and J. Liu Chiral ruthenium(II) polypyridyl complexes: stabilization of G-quadruplex DNA, inhibition of telomerase activity and cellular uptake PLoS ONE 7 2012 e50902
    • (2012) PLoS ONE , vol.7 , pp. 50902
    • Yu, Q.Q.1    Liu, Y.N.2    Wang, C.3    Sun, D.D.4    Yang, X.C.5    Liu, Y.Y.6    Liu, J.7
  • 34
    • 84859299618 scopus 로고    scopus 로고
    • Stabilization of G-quadruplex DNA, inhibition of telomerase activity and live cell imaging studies of chiral ruthenium(II) complexes
    • D.D. Sun, Y.N. Liu, D. Liu, R. Zhang, X.C. Yang, and J. Liu Stabilization of G-quadruplex DNA, inhibition of telomerase activity and live cell imaging studies of chiral ruthenium(II) complexes Chem. Eur. J. 18 2012 4285 4295
    • (2012) Chem. Eur. J. , vol.18 , pp. 4285-4295
    • Sun, D.D.1    Liu, Y.N.2    Liu, D.3    Zhang, R.4    Yang, X.C.5    Liu, J.6
  • 35
    • 84870489071 scopus 로고    scopus 로고
    • A naked-eye on-off-on molecular "light switch" based on a reversible "conformational switch" of G-quadruplex DNA
    • J.L. Yao, X. Gao, W.L. Sun, X.Z. Fan, S. Shi, and T.M. Yao A naked-eye on-off-on molecular "light switch" based on a reversible "conformational switch" of G-quadruplex DNA Inorg. Chem. 51 2012 12591 12593
    • (2012) Inorg. Chem. , vol.51 , pp. 12591-12593
    • Yao, J.L.1    Gao, X.2    Sun, W.L.3    Fan, X.Z.4    Shi, S.5    Yao, T.M.6
  • 36
    • 23844438712 scopus 로고    scopus 로고
    • Not so crystal clear: The structure of the human telomere G-quadruplex in solution differs from that present in a crystal
    • DOI 10.1093/nar/gki782
    • J. Li, J.J. Correia, L. Wang, J.O. Trent, and J.B. Chaires Not so crystal clear: the structure of the human telomere G-quadruplex in solution differs from that present in a crystal Nucleic Acids Res. 33 2005 4649 4659 (Pubitemid 41222579)
    • (2005) Nucleic Acids Research , vol.33 , Issue.14 , pp. 4649-4659
    • Li, J.1    Correia, J.J.2    Wang, L.3    Trent, J.O.4    Chaires, J.B.5
  • 37
    • 79960840968 scopus 로고    scopus 로고
    • Binding properties of human telomeric quadruplex multimers: A new route for drug design
    • A. Cummaro, I. Fotticchia, M. Franceschin, C. Giancola, and L. Petraccone Binding properties of human telomeric quadruplex multimers: a new route for drug design Biochimie 93 2011 1392 1400
    • (2011) Biochimie , vol.93 , pp. 1392-1400
    • Cummaro, A.1    Fotticchia, I.2    Franceschin, M.3    Giancola, C.4    Petraccone, L.5
  • 38
    • 47249157340 scopus 로고    scopus 로고
    • Binding of berberine to human telomeric quadruplex - Spectroscopic, calorimetric and molecular modeling studies
    • DOI 10.1111/j.1742-4658.2008.06541.x
    • A. Arora, C. Balasubramanian, N. Kumar, S. Agrawal, R.P. Ojha, and S. Maiti Binding of berberine to human telomeric quadruplex-spectroscopic, calorimetric and molecular modeling studies FEBS J. 275 2008 3971 3983 (Pubitemid 351990958)
    • (2008) FEBS Journal , vol.275 , Issue.15 , pp. 3971-3983
    • Arora, A.1    Balasubramanian, C.2    Kumar, N.3    Agrawal, S.4    Ojha, R.P.5    Maiti, S.6
  • 39
    • 68049109541 scopus 로고    scopus 로고
    • Reduced or diminished stabilization of the telomere G-quadruplex and inhibition of telomerase by small chemical ligands under molecular crowding condition
    • C. Zhao, K.W. Zheng, Y.H. Hao, and Z. Tan Reduced or diminished stabilization of the telomere G-quadruplex and inhibition of telomerase by small chemical ligands under molecular crowding condition J. Am. Chem. Soc. 131 2009 10430 10438
    • (2009) J. Am. Chem. Soc. , vol.131 , pp. 10430-10438
    • Zhao, C.1    Zheng, K.W.2    Hao, Y.H.3    Tan, Z.4
  • 40
    • 0024804717 scopus 로고
    • Voltammetric studies of the interaction of metal chelates with DNA. 2. Tris-chelated complexes of cobalt(III) and iron(II) with 1,10-phenanthroline and 2,2'-bipyridine
    • M.T. Carter, M. Rodriguez, and A. Bard Voltammetric studies of the interaction of metal chelates with DNA. 2. Tris-chelated complexes of cobalt(III) and iron(II) with 1,10-phenanthroline and 2,2′-bipyridine J. Am. Chem. Soc. 111 1989 8901 8911 (Pubitemid 20050086)
    • (1989) Journal of the American Chemical Society , vol.111 , Issue.24 , pp. 8901-8911
    • Carter, M.T.1    Rodriguez, M.2    Bard, A.J.3
  • 41
    • 78649553630 scopus 로고    scopus 로고
    • Studies on synthesis, characterization, and G-quadruplex binding of Ru(II) complexes containing two dppz ligands
    • J. Sun, Y. An, L. Zhang, H.Y. Chen, Y. Han, Y.J. Wang, Z.W. Mao, and L.N. Ji Studies on synthesis, characterization, and G-quadruplex binding of Ru(II) complexes containing two dppz ligands J. Inorg. Biochem. 105 2011 149 154
    • (2011) J. Inorg. Biochem. , vol.105 , pp. 149-154
    • Sun, J.1    An, Y.2    Zhang, L.3    Chen, H.Y.4    Han, Y.5    Wang, Y.J.6    Mao, Z.W.7    Ji, L.N.8
  • 42
    • 33746809014 scopus 로고    scopus 로고
    • Development of a fluorescent intercalator displacement assay (G4-FID) for establishing quadruplex-DNA affinity and selectivity of putative ligands
    • DOI 10.1016/j.bmcl.2006.06.067, PII S0960894X06007335
    • D. Monchaud, C. Allain, and M.P. Teulade-Fichou Development of a fluorescent intercalator displacement assay (G4-FID) for establishing quadruplex-DNA affinity and selectivity of putative ligands Bioorg. Med. Chem. Lett. 16 2006 4842 4845 (Pubitemid 44175856)
    • (2006) Bioorganic and Medicinal Chemistry Letters , vol.16 , Issue.18 , pp. 4842-4845
    • Monchaud, D.1    Allain, C.2    Teulade-Fichou, M.-P.3
  • 43
    • 79960700683 scopus 로고    scopus 로고
    • Fluorescence intercalator displacement assay for screening G4 ligands towards a variety of G-quadruplex structures
    • P.L.T. Tran, E. Largy, F. Hamon, M.P. Teulade-Fichou, and J.L. Mergny Fluorescence intercalator displacement assay for screening G4 ligands towards a variety of G-quadruplex structures Biochimie 93 2011 1288 1296
    • (2011) Biochimie , vol.93 , pp. 1288-1296
    • Tran, P.L.T.1    Largy, E.2    Hamon, F.3    Teulade-Fichou, M.P.4    Mergny, J.L.5
  • 45
    • 77956556862 scopus 로고    scopus 로고
    • Two metals are better than one: Investigations on the interactions between dinuclear metal complexes and quadruplex DNA
    • K. Suntharalingam, A.J.P. White, and R. Vilar Two metals are better than one: investigations on the interactions between dinuclear metal complexes and quadruplex DNA Inorg. Chem. 49 2010 8371 8380
    • (2010) Inorg. Chem. , vol.49 , pp. 8371-8380
    • Suntharalingam, K.1    White, A.J.P.2    Vilar, R.3
  • 46
    • 33751020853 scopus 로고    scopus 로고
    • Quadruplex DNA: Sequence, topology and structure
    • DOI 10.1093/nar/gkl655
    • S. Burge, G.N. Parkinson, P. Hazel, A.K. Todd, and S. Neidle Survey and summary quadruplex DNA: sequence, topology and structure Nucleic Acids Res. 34 2006 5402 5415 (Pubitemid 44742430)
    • (2006) Nucleic Acids Research , vol.34 , Issue.19 , pp. 5402-5415
    • Burge, S.1    Parkinson, G.N.2    Hazel, P.3    Todd, A.K.4    Neidle, S.5
  • 48
    • 39149132124 scopus 로고    scopus 로고
    • Circular dichroism to determine binding mode and affinity of ligand-DNA interactions
    • N.C. Garbett, P.A. Ragazzon, and J.B. Chaires Circular dichroism to determine binding mode and affinity of ligand-DNA interactions Nat. Protoc. 2 2007 3166 3172
    • (2007) Nat. Protoc. , vol.2 , pp. 3166-3172
    • Garbett, N.C.1    Ragazzon, P.A.2    Chaires, J.B.3
  • 49
    • 0035793647 scopus 로고    scopus 로고
    • Fluorescence resonance energy transfer as a probe for G-quartet formation by a telomeric repeat
    • J.L. Mergny, and J.C. Maurizot Fluorescence resonance energy transfer as a probe for G-quartet formation by a telomeric repeat ChemBioChem 2 2001 124 132
    • (2001) ChemBioChem , vol.2 , pp. 124-132
    • Mergny, J.L.1    Maurizot, J.C.2
  • 50
    • 0029670262 scopus 로고    scopus 로고
    • Molecular beacons: Probes that fluoresce upon hybridization
    • S. Tyagi, and F.R. Kramer Molecular beacons: probes that fluoresce upon hybridization Nat. Biotechnol. 14 1996 303 308
    • (1996) Nat. Biotechnol. , vol.14 , pp. 303-308
    • Tyagi, S.1    Kramer, F.R.2
  • 54
    • 54549117013 scopus 로고    scopus 로고
    • 5-N-methylated quindoline derivatives as telomeric G-quadruplex stabilizing ligands: Effects of 5-N positive charge on quadruplex binding affinity and cell proliferation
    • Y.J. Lu, T.M. Ou, J.H. Tan, J.Q. Hou, W.Y. Shao, D. Peng, N. Sun, X.D. Wang, W.B. Wu, X.Z. Bu, Z.S. Huang, D.L. Ma, K.Y. Wong, and L.Q. Gu 5-N-methylated quindoline derivatives as telomeric G-quadruplex stabilizing ligands: effects of 5-N positive charge on quadruplex binding affinity and cell proliferation J. Med. Chem. 51 2008 6381 6392
    • (2008) J. Med. Chem. , vol.51 , pp. 6381-6392
    • Lu, Y.J.1    Ou, T.M.2    Tan, J.H.3    Hou, J.Q.4    Shao, W.Y.5    Peng, D.6    Sun, N.7    Wang, X.D.8    Wu, W.B.9    Bu, X.Z.10    Huang, Z.S.11    Ma, D.L.12    Wong, K.Y.13    Gu, L.Q.14


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