Coupling bioorthogonal chemistries with artificial metabolism: Intracellular biosynthesis of azidohomoalanine and its incorporation into recombinant proteins

Molecules

Volumn 19, Issue 1, 2014, Pages 1004-1022

  Ma, Ying ^a   Biava, Hernán ^a   Contestabile, Roberto ^b   Budisa, Nediljko ^a   Di Salvo, Martino Luigi ^b  

^a TECHNISCHE UNIVERSITÄT BERLIN   (Germany)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Artificial metabolism metabolic engineering; Bioorthogonality; Click chemistry; Genetic code expansion; L Azidohomoalanine; L methionine; O Acetyl L homoserine sulfhydrylase; Posttranslational modifications

Indexed keywords

ALANINE; AZIDOHOMOALANINE; BACTERIAL PROTEIN; BARSTAR PROTEIN, BACILLUS AMYLOLIQUEFACIENS; DRUG DERIVATIVE; RECOMBINANT PROTEIN;

ARTICLE; BIOSYNTHESIS; CLICK CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; ESCHERICHIA COLI; FERMENTATION; GENETIC ENGINEERING; METABOLISM; PROTEIN PROCESSING;

ALANINE; BACTERIAL PROTEINS; CLICK CHEMISTRY; ESCHERICHIA COLI; FERMENTATION; GENETIC ENGINEERING; METABOLIC NETWORKS AND PATHWAYS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84893091826     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules19011004     Document Type: Article

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