Effects of the root bark of Paeonia suffruticosa on mitochondria-mediated neuroprotection in an MPTP-induced model of Parkinson's disease

Food and Chemical Toxicology

Volumn 65, Issue , 2014, Pages 293-300

  Kim, Hyo Geun ^a   Park, Gunhyuk ^a   Piao, Ying ^b   Kang, Min Seo ^c   Pak, Youngmi Kim ^b   Hong, Seon Pyo ^a   Oh, Myung Sook ^a  

^a Kyung Hee University   (South Korea)

^b Kyung Hee University Hospital   (South Korea)

^c NONE   (China)

Author keywords

Mitochondria dysfunction; MPTP; Paeonia suffruticosa; Parkinson's disease

Indexed keywords

CASPASE 3; CYTOCHROME C; DOPAMINE; HISTONE H2AX; MITOCHONDRIAL TRANSCRIPTION FACTOR A; PAEONIA SUFFRUTICOSA EXTRACT; PROTEIN KINASE B; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; PHOSPHOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BARK; BRADYKINESIA; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOPAMINERGIC NERVE CELL; DRUG MECHANISM; DRUG SCREENING; EMBRYO; ENZYME ACTIVATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LOCOMOTION; MALE; MESENCEPHALON; MITOCHONDRION; MOUSE; NERVE INJURY; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PLANT ROOT; PROTEIN EXPRESSION; SUBSTANTIA NIGRA PARS COMPACTA; BRAIN MITOCHONDRION; CONTROLLED STUDY; NERVE CELL LESION; PAEONIA SUFFRUTICOSA; PROTEIN FUNCTION; PROTEIN SECRETION; RAT;

PAEONIA SUFFRUTICOSA;

MITOCHONDRIA DYSFUNCTION; MPTP; PAEONIA SUFFRUTICOSA; PARKINSON'S DISEASE;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DISEASE MODELS, ANIMAL; FEMALE; MALE; MICE; MICE, INBRED C57BL; NEUROPROTECTIVE AGENTS; PAEONIA; PARKINSONIAN DISORDERS; PLANT EXTRACTS; PLANT ROOTS; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84893074970     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.12.037     Document Type: Article

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