Ropinirole protects against 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-induced neurotoxicity in mice via anti-apoptotic mechanism

Pharmacology Biochemistry and Behavior

Volumn 104, Issue 1, 2013, Pages 163-168

  Park, Gunhyuk ^a   Park, Young Joon ^b   Yang, Hyun Ok ^c   Oh, Myung Sook ^a  

^a Kyung Hee University   (South Korea)

^b Pharmaceutical Research Institute   (South Korea)

^c Korea Institute of Science and Technology   (South Korea)

Author keywords

Apoptosis; Bradykinesia; MPTP; Neuroprotection; Parkinson's disease; Ropinirole

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; CASPASE 3; NUCLEAR RESPIRATORY FACTOR 1; PROTEIN BAX; PROTEIN BCL 2; ROPINIROLE; TRANSCRIPTION FACTOR AP 1; TYROSINE 3 MONOOXYGENASE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRADYKINESIA; CONTROLLED STUDY; CORPUS STRIATUM; CYTOSOL; DRUG STRUCTURE; IMMUNOHISTOCHEMISTRY; MALE; MOTOR COORDINATION; MOUSE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; ROTAROD TEST; SUBSTANTIA NIGRA PARS COMPACTA; WESTERN BLOTTING;

ANIMALS; ANTIPARKINSON AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BEHAVIOR, ANIMAL; CASPASE 3; CYTOCHROMES C; DNA-BINDING PROTEINS; DOPAMINE AGONISTS; DOPAMINERGIC NEURONS; HIGH MOBILITY GROUP PROTEINS; INDOLES; MALE; MICE; MICE, INBRED C57BL; MPTP POISONING; NEUROPROTECTIVE AGENTS; NUCLEAR RESPIRATORY FACTOR 1; PARKINSONIAN DISORDERS; PROTO-ONCOGENE PROTEINS C-BCL-2; SUBSTANTIA NIGRA;

MUS;

EID: 84873703967     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2013.01.017     Document Type: Article

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