-
2
-
-
0032535245
-
Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators
-
Morimoto RI. 1998. Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators. Genes Dev. 12:3788-3796.
-
(1998)
Genes Dev.
, vol.12
, pp. 3788-3796
-
-
Morimoto, R.I.1
-
3
-
-
16844366162
-
Polo-like kinase 1 phosphorylates heat shock transcription factor 1 and mediates its nuclear translocation during heat stress
-
Kim SA, Yoon JH, Lee SH, Ahn SG. 2005. Polo-like kinase 1 phosphorylates heat shock transcription factor 1 and mediates its nuclear translocation during heat stress. J. Biol. Chem. 280:12653-12657.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 12653-12657
-
-
Kim, S.A.1
Yoon, J.H.2
Lee, S.H.3
Ahn, S.G.4
-
4
-
-
0028352287
-
Yeast heat shock transcription factor contains a flexible linker between the DNAbinding and trimerization domains: implications for DNA binding by trimeric proteins
-
Flick KE, Gonzalez L, Jr, Harrison CJ, Nelson HC. 1994. Yeast heat shock transcription factor contains a flexible linker between the DNAbinding and trimerization domains: implications for DNA binding by trimeric proteins. J. Biol. Chem. 269:12475-12481.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 12475-12481
-
-
Flick, K.E.1
Gonzalez Jr., L.2
Harrison, C.J.3
Nelson, H.C.4
-
5
-
-
0032031725
-
Molecular chaperones as HSF1-specific transcriptional repressors
-
Shi Y, Mosser DD, Morimoto RI. 1998. Molecular chaperones as HSF1-specific transcriptional repressors. Genes Dev. 12:654-666.
-
(1998)
Genes Dev.
, vol.12
, pp. 654-666
-
-
Shi, Y.1
Mosser, D.D.2
Morimoto, R.I.3
-
6
-
-
18244384703
-
Analysis of phosphorylation of human heat shock factor 1 in cells experiencing a stress
-
doi:10.1186/1471-2091-6-4
-
Guettouche T, Boellmann F, Lane WS, Voellmy R. 2005. Analysis of phosphorylation of human heat shock factor 1 in cells experiencing a stress. BMC Biochem. 6:4. doi:10.1186/1471-2091-6-4.
-
(2005)
BMC Biochem.
, vol.6
, pp. 4
-
-
Guettouche, T.1
Boellmann, F.2
Lane, W.S.3
Voellmy, R.4
-
7
-
-
78649721996
-
Protein kinase A binds and activates heat shock factor 1
-
doi:10.1371/journal.pone.0013830
-
Murshid A, Chou SD, Prince T, Zhang Y, Bharti A, Calderwood SK. 2010. Protein kinase A binds and activates heat shock factor 1. PLoS One 5:e13830. doi:10.1371/journal.pone.0013830.
-
(2010)
PLoS One
, vol.5
-
-
Murshid, A.1
Chou, S.D.2
Prince, T.3
Zhang, Y.4
Bharti, A.5
Calderwood, S.K.6
-
8
-
-
17844386323
-
Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1
-
Holmberg CI, Hietakangas V, Mikhailov A, Rantanen JO, Kallio M, Meinander A, Hellman J, Morrice N, MacKintosh C, Morimoto RI. Eriksson JE, Sistonen L. 2001. Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1. EMBO J. 20:3800-3810.
-
(2001)
EMBO J.
, vol.20
, pp. 3800-3810
-
-
Holmberg, C.I.1
Hietakangas, V.2
Mikhailov, A.3
Rantanen, J.O.4
Kallio, M.5
Meinander, A.6
Hellman, J.7
Morrice, N.8
MacKintosh, C.9
Morimoto, R.I.10
Eriksson, J.E.11
Sistonen, L.12
-
9
-
-
0037385213
-
Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMOmodification of heat shock factor 1
-
Hietakangas V, Ahlskog JK, Jakobsson AM, Hellesuo M, Sahlberg NM, Holmberg CI, Mikhailov A, Palvimo JJ, Pirkkala L, Sistonen L. 2003. Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMOmodification of heat shock factor 1. Mol. Cell. Biol. 23:2953-2968.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 2953-2968
-
-
Hietakangas, V.1
Ahlskog, J.K.2
Jakobsson, A.M.3
Hellesuo, M.4
Sahlberg, N.M.5
Holmberg, C.I.6
Mikhailov, A.7
Palvimo, J.J.8
Pirkkala, L.9
Sistonen, L.10
-
10
-
-
30444440554
-
PDSM, a motif for phosphorylation-dependent SUMO modification
-
Hietakangas V, Anckar J, Blomster HA, Fujimoto M, Palvimo JJ, Nakai A, Sistonen L. 2006. PDSM, a motif for phosphorylation-dependent SUMO modification. Proc. Natl. Acad. Sci. U. S. A. 103:45-50.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 45-50
-
-
Hietakangas, V.1
Anckar, J.2
Blomster, H.A.3
Fujimoto, M.4
Palvimo, J.J.5
Nakai, A.6
Sistonen, L.7
-
11
-
-
31344444419
-
Inhibition of DNA binding by differential sumoylation of heat shock factors
-
Anckar J, Hietakangas V, Denessiouk K, Thiele DJ, Johnson MS, Sistonen L. 2006. Inhibition of DNA binding by differential sumoylation of heat shock factors. Mol. Cell. Biol. 26:955-964.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 955-964
-
-
Anckar, J.1
Hietakangas, V.2
Denessiouk, K.3
Thiele, D.J.4
Johnson, M.S.5
Sistonen, L.6
-
12
-
-
84884211458
-
Prolyl isomerase Pin1 downregulates tumor suppressor RUNX3 in breast cancer
-
Tsang N, Wu YH, Lim JS, Wee Ong C, Salto-Tellez M, Ito K, Ito Y, Chen LF. 2012 Prolyl isomerase Pin1 downregulates tumor suppressor RUNX3 in breast cancer. Oncogene 32:1488-1496.
-
(2012)
Oncogene
, vol.32
, pp. 1488-1496
-
-
Tsang, N.1
Wu, Y.H.2
Lim, J.S.3
Wee Ong, C.4
Salto-Tellez, M.5
Ito, K.6
Ito, Y.7
Chen, L.F.8
-
13
-
-
84863611032
-
Pin1 protein regulates Smad protein signaling and pulmonary fibrosis
-
Shen ZJ, Braun RK, Hu J, Xie Q, Chu H, Love RB, Stodola LA, Rosenthal LA, Szakaly RJ, Sorkness RL, Malter JS. 2012. Pin1 protein regulates Smad protein signaling and pulmonary fibrosis. J. Biol. Chem. 287:23294-23305.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 23294-23305
-
-
Shen, Z.J.1
Braun, R.K.2
Hu, J.3
Xie, Q.4
Chu, H.5
Love, R.B.6
Stodola, L.A.7
Rosenthal, L.A.8
Szakaly, R.J.9
Sorkness, R.L.10
Malter, J.S.11
-
14
-
-
18344387559
-
Phosphorylation-specific prolyl isomerization: is there an underlying theme?
-
Wulf G, Finn G, Suizu F, Lu KP. 2005. Phosphorylation-specific prolyl isomerization: is there an underlying theme? Nat. Cell Biol. 7:435-441.
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 435-441
-
-
Wulf, G.1
Finn, G.2
Suizu, F.3
Lu, K.P.4
-
15
-
-
80053299231
-
Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins
-
Liou YC, Zhou XZ, Lu KP. 2011. Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins. Trends Biochem. Sci. 36:501-514.
-
(2011)
Trends Biochem. Sci.
, vol.36
, pp. 501-514
-
-
Liou, Y.C.1
Zhou, X.Z.2
Lu, K.P.3
-
16
-
-
79951539518
-
Prolyl isomerase pin1 protects mice from endotoxin shock
-
doi:10.1371/journal.pone.0014656
-
Akiyama H, Misawa T, Ono M, Uchida C, Uchida T. 2011. Prolyl isomerase pin1 protects mice from endotoxin shock. PLoS One 6:e14656. doi:10.1371/journal.pone.0014656.
-
(2011)
PLoS One
, vol.6
-
-
Akiyama, H.1
Misawa, T.2
Ono, M.3
Uchida, C.4
Uchida, T.5
-
17
-
-
37549031354
-
A suppressive role of the prolyl isomerase Pin1 in cellular apoptosis mediated by the death-associated protein Daxx
-
Ryo A, Hirai A, Nishi M, Liou YC, Perrem K, Lin SC, Hirano H, Lee SW, Aoki I. 2007. A suppressive role of the prolyl isomerase Pin1 in cellular apoptosis mediated by the death-associated protein Daxx. J. Biol. Chem. 282:36671-36681.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 36671-36681
-
-
Ryo, A.1
Hirai, A.2
Nishi, M.3
Liou, Y.C.4
Perrem, K.5
Lin, S.C.6
Hirano, H.7
Lee, S.W.8
Aoki, I.9
-
18
-
-
0042476570
-
Pin1 regulates the timing of mammalian primordial germ cell proliferation
-
Atchison FW, Capel B, Means AR. 2003. Pin1 regulates the timing of mammalian primordial germ cell proliferation. Development 130:3579-3586.
-
(2003)
Development
, vol.130
, pp. 3579-3586
-
-
Atchison, F.W.1
Capel, B.2
Means, A.R.3
-
19
-
-
0031467707
-
HSF1 granules: a novel stressinduced nuclear compartment of human cells
-
Cotto, J., Fox, S. and Morimoto, R. 1997 HSF1 granules: a novel stressinduced nuclear compartment of human cells. J. Cell Sci. 110(Pt 23):2925-2934.
-
(1997)
J. Cell Sci
, vol.110
, Issue.PART 23
, pp. 2925-2934
-
-
Cotto, J.1
Fox, S.2
Morimoto, R.3
-
20
-
-
0347432388
-
Stress-induced transcription of satellite III repeats
-
Jolly C, Metz A, Govin J, Vigneron M, Turner BM, Khochbin S, Vourc'h C. 2004 Stress-induced transcription of satellite III repeats. J. Cell Biol. 164:25-33.
-
(2004)
J. Cell Biol
, vol.164
, pp. 25-33
-
-
Jolly, C.1
Metz, A.2
Govin, J.3
Vigneron, M.4
Turner, B.M.5
Khochbin, S.6
Vourc'h, C.7
-
21
-
-
0037018158
-
In vivo binding of active heat shock transcription factor 1 to human chromosome 9 heterochromatin during stress
-
Jolly C, Konecny L, Grady DL, Kutskova YA, Cotto JJ, Morimoto RI, Vourc'h C. 2002 In vivo binding of active heat shock transcription factor 1 to human chromosome 9 heterochromatin during stress. J. Cell Biol. 156:775-781.
-
(2002)
J. Cell Biol
, vol.156
, pp. 775-781
-
-
Jolly, C.1
Konecny, L.2
Grady, D.L.3
Kutskova, Y.A.4
Cotto, J.J.5
Morimoto, R.I.6
Vourc'h, C.7
-
22
-
-
0008233581
-
Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent
-
Ranganathan R, Lu KP, Hunter T, Noel JP. 1997. Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent. Cell 89:875-886.
-
(1997)
Cell
, vol.89
, pp. 875-886
-
-
Ranganathan, R.1
Lu, K.P.2
Hunter, T.3
Noel, J.P.4
-
23
-
-
0040017910
-
Function of WW domains as phosphoserine- or phosphothreonine-binding modules
-
Lu PJ, Zhou XZ, Shen M, Lu KP. 1999. Function of WW domains as phosphoserine- or phosphothreonine-binding modules. Science 283:1325-1328.
-
(1999)
Science
, vol.283
, pp. 1325-1328
-
-
Lu, P.J.1
Zhou, X.Z.2
Shen, M.3
Lu, K.P.4
-
24
-
-
0031055277
-
Hyperphosphorylation of heat shock transcription factor 1 is correlated with transcriptional competence and slow dissociation of active factor trimers
-
Xia W, Voellmy R. 1997. Hyperphosphorylation of heat shock transcription factor 1 is correlated with transcriptional competence and slow dissociation of active factor trimers. J. Biol. Chem. 272:4094-4102.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 4094-4102
-
-
Xia, W.1
Voellmy, R.2
-
25
-
-
17744372861
-
Roles of the heat shock transcription factors in regulation of the heat shock response and beyond
-
Pirkkala L, Nykanen P, Sistonen L. 2001. Roles of the heat shock transcription factors in regulation of the heat shock response and beyond. FASEB J. 15:1118-1131.
-
(2001)
FASEB J.
, vol.15
, pp. 1118-1131
-
-
Pirkkala, L.1
Nykanen, P.2
Sistonen, L.3
-
26
-
-
11144243412
-
Modulation of neurodegeneration by molecular chaperones
-
Muchowski PJ, Wacker JL. 2005. Modulation of neurodegeneration by molecular chaperones. Nat. Rev. Neurosci. 6:11-22.
-
(2005)
Nat. Rev. Neurosci.
, vol.6
, pp. 11-22
-
-
Muchowski, P.J.1
Wacker, J.L.2
-
27
-
-
33344470452
-
Pin1 mediates neural-specific activation of the mitochondrial apoptotic machinery
-
Becker EB, Bonni A. 2006. Pin1 mediates neural-specific activation of the mitochondrial apoptotic machinery. Neuron 49:655-662.
-
(2006)
Neuron
, vol.49
, pp. 655-662
-
-
Becker, E.B.1
Bonni, A.2
-
28
-
-
0033600242
-
The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein
-
Lu PJ, Wulf G, Zhou XZ, Davies P, Lu KP. 1999. The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein. Nature 399:784-788.
-
(1999)
Nature
, vol.399
, pp. 784-788
-
-
Lu, P.J.1
Wulf, G.2
Zhou, X.Z.3
Davies, P.4
Lu, K.P.5
-
29
-
-
10744223839
-
CHIP activates HSF1 and confers protection against apoptosis and cellular stress
-
Dai Q, Zhang C, Wu Y, McDonough H, Whaley RA, Godfrey V, Li HH, Madamanchi N, Xu W, Neckers L, Cyr D, Patterson C. 2003. CHIP activates HSF1 and confers protection against apoptosis and cellular stress. EMBO J. 22:5446-5458.
-
(2003)
EMBO J.
, vol.22
, pp. 5446-5458
-
-
Dai, Q.1
Zhang, C.2
Wu, Y.3
McDonough, H.4
Whaley, R.A.5
Godfrey, V.6
Li, H.H.7
Madamanchi, N.8
Xu, W.9
Neckers, L.10
Cyr, D.11
Patterson, C.12
-
30
-
-
1642569697
-
DAXX interacts with heat shock factor 1 during stress activation and enhances its transcriptional activity
-
Boellmann F, Guettouche T, Guo Y, Fenna M, Mnayer L, Voellmy R. 2004. DAXX interacts with heat shock factor 1 during stress activation and enhances its transcriptional activity. Proc. Natl. Acad. Sci. U. S. A. 101:4100-4105.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 4100-4105
-
-
Boellmann, F.1
Guettouche, T.2
Guo, Y.3
Fenna, M.4
Mnayer, L.5
Voellmy, R.6
-
31
-
-
0031866191
-
HSP90 interacts with and regulates the activity of heat shock factor 1 in Xenopus oocytes
-
Ali A, Bharadwaj S, O'Carroll R, Ovsenek N. 1998. HSP90 interacts with and regulates the activity of heat shock factor 1 in Xenopus oocytes. Mol. Cell. Biol. 18:4949-4960.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 4949-4960
-
-
Ali, A.1
Bharadwaj, S.2
O'Carroll, R.3
Ovsenek, N.4
-
32
-
-
60749101582
-
Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1
-
Westerheide SD, Anckar J, Stevens SM, Jr, Sistonen L, Morimoto RI. 2009. Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1. Science 323:1063-1066.
-
(2009)
Science
, vol.323
, pp. 1063-1066
-
-
Westerheide, S.D.1
Anckar, J.2
Stevens, S.M.3
Sistonen, L.4
Morimoto, R.I.5
-
33
-
-
84871750894
-
mTOR is essential for the proteotoxic stress response, HSF1 activation and heat shock protein synthesis
-
doi:10.1371/journal.pone.0039679
-
Chou SD, Prince T, Gong J, Calderwood SK. 2012. mTOR is essential for the proteotoxic stress response, HSF1 activation and heat shock protein synthesis. PLoS One 7:e39679. doi:10.1371/journal.pone.0039679.
-
(2012)
PLoS One
, vol.7
-
-
Chou, S.D.1
Prince, T.2
Gong, J.3
Calderwood, S.K.4
-
34
-
-
0029916122
-
A human peptidyl-prolyl isomerase essential for regulation of mitosis
-
Lu KP, Hanes SD, Hunter T. 1996. A human peptidyl-prolyl isomerase essential for regulation of mitosis. Nature 380:544-547.
-
(1996)
Nature
, vol.380
, pp. 544-547
-
-
Lu, K.P.1
Hanes, S.D.2
Hunter, T.3
-
35
-
-
33645300736
-
The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production
-
Pastorino L, Sun A, Lu PJ, Zhou XZ, Balastik M, Finn G, Wulf G, Lim J, Li SH, Li X, Xia W, Nicholson LK, Lu KP. 2006. The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production. Nature 440:528-534.
-
(2006)
Nature
, vol.440
, pp. 528-534
-
-
Pastorino, L.1
Sun, A.2
Lu, P.J.3
Zhou, X.Z.4
Balastik, M.5
Finn, G.6
Wulf, G.7
Lim, J.8
Li, S.H.9
Li, X.10
Xia, W.11
Nicholson, L.K.12
Lu, K.P.13
-
36
-
-
84872507367
-
The SIRT1 modulators AROS and DBC1 regulate HSF1 activity and the heat shock response
-
doi:10.1371/journal.pone.0054364
-
Raynes R, Pombier KM, Nguyen K, Brunquell J, Mendez JE, Westerheide SD. 2013. The SIRT1 modulators AROS and DBC1 regulate HSF1 activity and the heat shock response. PLoS One 8:e54364. doi:10.1371/journal.pone.0054364.
-
(2013)
PLoS One
, vol.8
-
-
Raynes, R.1
Pombier, K.M.2
Nguyen, K.3
Brunquell, J.4
Mendez, J.E.5
Westerheide, S.D.6
-
37
-
-
84862930510
-
HSF-1 regulators DDL-1/2 link insulin-like signaling to heat-shock responses and modulation of longevity
-
Chiang WC, Ching TT, Lee HC, Mousigian C, Hsu AL. 2012. HSF-1 regulators DDL-1/2 link insulin-like signaling to heat-shock responses and modulation of longevity. Cell 148:322-334.
-
(2012)
Cell
, vol.148
, pp. 322-334
-
-
Chiang, W.C.1
Ching, T.T.2
Lee, H.C.3
Mousigian, C.4
Hsu, A.L.5
-
38
-
-
77956672926
-
Loss of Hsp110 leads to age-dependent tau hyperphosphorylation and early accumulation of insoluble amyloid beta
-
Eroglu B, Moskophidis D, Mivechi NF. 2010. Loss of Hsp110 leads to age-dependent tau hyperphosphorylation and early accumulation of insoluble amyloid beta. Mol. Cell. Biol. 30:4626-4643.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 4626-4643
-
-
Eroglu, B.1
Moskophidis, D.2
Mivechi, N.F.3
|